{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,2,11]],"date-time":"2025-02-11T05:21:23Z","timestamp":1739251283353,"version":"3.37.0"},"reference-count":43,"publisher":"Akademiai Kiado Zrt.","issue":"29","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2009,7,1]]},"abstract":"<jats:p>A h\u00e9tk\u00f6znapi klinikai gyakorlatban a k\u00f6zponti idegrendszer gomb\u00e1s fert\u0151z\u00e9sei gyakoribb\u00e1 v\u00e1ltak. Ennek legink\u00e1bb ismert okai a kortikoszteroidok, immunszuppressz\u00edv gy\u00f3gyszerek, citosztatikumok, antibiotikumok egyre sz\u00e9lesebb k\u00f6r\u0171 alkalmaz\u00e1sa, az AIDS elterjed\u00e9se, az \u00e9letben tarthat\u00f3 korasz\u00fcl\u00f6ttek mind nagyobb sz\u00e1ma. A szerz\u0151k a diagnosztikus probl\u00e9m\u00e1k illusztr\u00e1l\u00e1s\u00e1ra eseteket mutatnak be.<jats:italic>Esetismertet\u00e9s:<\/jats:italic>1. Multifok\u00e1lis haemorrhagi\u00e1s agyi infarktus generaliz\u00e1lt aspergillosis k\u00f6vetkezt\u00e9ben, k\u00f6penysejtes malignus lymphom\u00e1ban. 2. \u00c9retlen korasz\u00fcl\u00f6ttben kialakult cerebralis microabscessusok sziszt\u00e9m\u00e1s candidiasis talaj\u00e1n. 3. A comb t\u00e9rfoglal\u00f3 daganat\u00e1t ut\u00e1nz\u00f3, az agyban radiol\u00f3giailag metaszt\u00e1zisnak t\u0171n\u0151 t\u00e1lyogot, a t\u00fcd\u0151ben gyullad\u00e1st okoz\u00f3 lethalis actinomycosis. 4. Idegseb\u00e9szeti sz\u00f6vetmint\u00e1b\u00f3l diagnosztiz\u00e1lt nocardiosis. A visszat\u00e9r\u0151, migr\u00e1l\u00f3 pneumonia, majd agyi t\u00e1lyogok miatt hosszasan kezelt beteg a megfelel\u0151 ter\u00e1pi\u00e1ra gy\u00f3gyult.<jats:italic>Megbesz\u00e9l\u00e9s:<\/jats:italic>Fel kell k\u00e9sz\u00fcln\u00fcnk a vesz\u00e9lyeztetett betegek gomb\u00e1s infekci\u00f3j\u00e1nak kialakul\u00e1s\u00e1ra \u2013 els\u0151sorban aspergillosisra \u00e9s candidiasisra \u2013, ezek jelent\u0151s r\u00e9sze a k\u00f6zponti idegrendszerre is r\u00e1terjed. Az actinomycosis \u00e9s a nocardiosis kezel\u00e9sre jobban reag\u00e1l, felismer\u00e9s\u00fck, kezel\u00e9s\u00fck \u00e9letment\u0151.<jats:italic>K\u00f6vetkeztet\u00e9sek:<\/jats:italic>Ter\u00e1pi\u00e1s kil\u00e1t\u00e1saink javulnak, ha a nagy rizik\u00f3j\u00fa betegek jelent\u0151s mortalit\u00e1st okoz\u00f3 mycosisainak lehet\u0151s\u00e9g\u00e9vel sz\u00e1molva, azokat id\u0151ben \u2013 m\u00e9g az idegrendszeri r\u00e9szv\u00e9tel el\u0151tt \u2013 k\u00f3rism\u00e9zz\u00fck \u00e9s kezelj\u00fck.<\/jats:p>","DOI":"10.1556\/oh.2009.28657","type":"journal-article","created":{"date-parts":[[2009,7,10]],"date-time":"2009-07-10T01:15:38Z","timestamp":1247188538000},"page":"1367-1374","source":"Crossref","is-referenced-by-count":2,"title":["Manifestations of systemic mycoses and related infections in the central nervous system"],"prefix":"10.1556","volume":"150","author":[{"given":"Bal\u00e1zs","family":"Tahin","sequence":"first","affiliation":[{"name":"1 Vas Megyei Markusovszky K\u00f3rh\u00e1z Nonprofit Zrt. 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