{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2022,4,3]],"date-time":"2022-04-03T22:33:28Z","timestamp":1649025208478},"reference-count":8,"publisher":"Akademiai Kiado Zrt.","issue":"43","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2009,10,1]]},"abstract":"<jats:p>A szerz\u0151k egy 35 \u00e9ves n\u0151beteg k\u00f3rt\u00f6rt\u00e9net\u00e9t ismertetik, akin\u00e9l 29 \u00e9ves kor\u00e1ban szeronegat\u00edv rheumatoid arthritist igazoltak a reumatol\u00f3giai oszt\u00e1lyon. A betegs\u00e9g remisszi\u00f3j\u00e1t sikeres gravidit\u00e1s k\u00f6vette, majd k\u00e9t \u00e9vvel k\u00e9s\u0151bb kiz\u00e1r\u00f3lag axi\u00e1lis t\u00fcneteket mutat\u00f3 spondylarthritist diagnosztiz\u00e1ltak. A major hisztokompatibilit\u00e1si komplex vizsg\u00e1lata sor\u00e1n a hagyom\u00e1nyos szerol\u00f3giai m\u00f3dszerekkel a HLA B27 spondylarthritis ankylopoetic\u00e1ra jellemz\u0151, valamint HLA DR1 rheumatoid arthritisre jellemz\u0151 haplot\u00edpust mutattak ki. A HLA DRB-polimorfizmus vizsg\u00e1lata sor\u00e1n a rheumatoid arthritis l\u00e9trej\u00f6tt\u00e9ben \u00e9s k\u00f3rlefoly\u00e1s\u00e1ban szerepet j\u00e1tsz\u00f3 HLA DR B1 0101 all\u00e9l jelenl\u00e9t\u00e9t igazolt\u00e1k. A betegben teh\u00e1t ritka kombin\u00e1ci\u00f3k\u00e9nt a spondylarthritis ankylopoetica \u00e9s a rheumatoid arthritis l\u00e9trej\u00f6tt\u00e9ben is szerepet j\u00e1tsz\u00f3 HLA-form\u00e1ci\u00f3 egyar\u00e1nt megtal\u00e1lhat\u00f3 volt.<\/jats:p>","DOI":"10.1556\/oh.2009.28661","type":"journal-article","created":{"date-parts":[[2009,10,8]],"date-time":"2009-10-08T01:08:05Z","timestamp":1254964085000},"page":"2000-2003","source":"Crossref","is-referenced-by-count":0,"title":["Two faces of an illness: ankylosing spondylitis developed after rheumatoid arthritis"],"prefix":"10.1556","volume":"150","author":[{"given":"Eszter","family":"Varga","sequence":"first","affiliation":[{"name":"1 Vas Megyei Markusovszky K\u00f3rh\u00e1z Nonprofit Zrt. 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