{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2023,5,27]],"date-time":"2023-05-27T03:10:07Z","timestamp":1685157007247},"reference-count":17,"publisher":"Akademiai Kiado Zrt.","issue":"43","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2009,10,1]]},"abstract":"<jats:p>A funkcion\u00e1lis gasztroenterol\u00f3giai vizsg\u00e1latok (intraoesophagealis pH-m\u00e9r\u00e9s, nyel\u0151cs\u0151-manometria, szcintigr\u00e1fia, impedanciavizsg\u00e1lat) egyre ink\u00e1bb n\u00e9lk\u00fcl\u00f6zhetetlenek az endoszk\u00f3posan negat\u00edv fels\u0151 gastrointestinalis panaszokkal rendelkez\u0151 betegek diagnosztik\u00e1j\u00e1ban \u00e9s adekv\u00e1t kezel\u00e9s\u00e9ben.<jats:italic>Betegek \u00e9s m\u00f3dszer:<\/jats:italic>Munk\u00e1nkban n\u00e9gy olyan t\u00edpusos esetet ismertet\u00fcnk, amikor e vizsg\u00e1latok seg\u00edts\u00e9g\u00e9vel siker\u00fclt a korrekt diagn\u00f3zist fel\u00e1ll\u00edtani, \u00e9s ennek alapj\u00e1n a megfelel\u0151 ter\u00e1pi\u00e1s strat\u00e9gi\u00e1t kialak\u00edtani. K\u00f6z\u00fcl\u00fck k\u00e9t fiatal beteg gastrooesophagealis reflux t\u00fcnetegy\u00fcttes miatt, k\u00e9t beteg pedig nyel\u00e9si panaszok miatt ker\u00fclt vizsg\u00e1latokra. Az intraoesophagealis pH-m\u00e9r\u00e9st Zinetics t\u00f6bbsz\u00f6r haszn\u00e1latos, 24 \u00f3r\u00e1s intraoesophagealis egy-, illetve k\u00e9tcsatorn\u00e1s kat\u00e9terrel, a nyel\u0151cs\u0151-manometri\u00e1t Zinetics n\u00e9gycsatorn\u00e1s EMC-kat\u00e9terrel, folyad\u00e9kperf\u00fazi\u00f3s m\u00f3dszerrel v\u00e9gezt\u00fck.<jats:italic>Esetismertet\u00e9sek:<\/jats:italic>Refluxt\u00fcnetekkel rendelkez\u0151 betegeink k\u00f6z\u00fcl egyik\u00fckn\u00e9l als\u00f3 oesophagussphincter-inkompetencia talaj\u00e1n kialakult 24 \u00f3r\u00e1s pH-m\u00e9r\u00e9ssel igazolt k\u00f3ros gastrooesophagealis savas refluxot \u00e9szlelt\u00fcnk hiatus hernia \u00e9s megtartott nyel\u0151cs\u0151-perisztaltika mellett az oesophagealis \u00e9s extraoesophagealis t\u00fcnetek h\u00e1tter\u00e9ben. Mivel teljes panaszmentess\u00e9ge protonpumpag\u00e1tl\u00f3 kezel\u00e9ssel sem volt biztos\u00edthat\u00f3, antirefluxm\u0171t\u00e9tet indik\u00e1ltunk. M\u00e1sik beteg\u00fcnkn\u00e9l norm\u00e1lis oesophagus-pH-m\u00e9r\u00e9si \u00e9s a manometri\u00e1s eredm\u00e9ny alapj\u00e1n hiperszenzit\u00edv oesophagust v\u00e9lem\u00e9nyezt\u00fcnk, a protonpumpag\u00e1tl\u00f3 adagj\u00e1t dupl\u00e1j\u00e1ra emelt\u00fck. Jelenleg mindk\u00e9t beteg\u00fcnk panaszmentes. M\u00e1sik k\u00e9t beteg\u00fcnk nyel\u00e9si k\u00e9ptelens\u00e9gr\u0151l, jelent\u0151s fogy\u00e1sr\u00f3l panaszkodott. A nyel\u0151cs\u0151-manometria alapj\u00e1n mindkett\u0151j\u00fckn\u00e9l nem relax\u00e1l\u00f3 als\u00f3 oesophagealis sphinctert, hipomotilis nyel\u0151cs\u00f6vet, achalasi\u00e1nak megfelel\u0151 k\u00e9pet \u00e9szlelt\u00fcnk. Endoszk\u00f3pos nyel\u0151cs\u0151-ballondilat\u00e1ci\u00f3t k\u00f6vet\u0151en a betegek nyel\u00e9se rendez\u0151d\u00f6tt, t\u00e1pl\u00e1lkoz\u00e1sra k\u00e9pess\u00e9 v\u00e1ltak.<jats:italic>K\u00f6vetkeztet\u00e9sek:<\/jats:italic>Eseteink j\u00f3l p\u00e9ld\u00e1zz\u00e1k a 24 \u00f3r\u00e1s pH-m\u00e9r\u00e9s \u00e9s a manometria szerep\u00e9nek jelent\u0151s\u00e9g\u00e9t a gastrooesophagealis refluxbetegs\u00e9g \u00e9s a nyel\u00e9si nehez\u00edtetts\u00e9g, az extraoesophagealis manifeszt\u00e1ci\u00f3k, a nem cardialis eredet\u0171 mellkasi f\u00e1jdalom diagnosztik\u00e1j\u00e1ban. E vizsg\u00e1latok fontos szerepet j\u00e1tszanak a helyes ter\u00e1pi\u00e1s strat\u00e9gia kialak\u00edt\u00e1s\u00e1ban, a m\u0171t\u00e9ti vagy endoszk\u00f3pos operat\u00edv kezel\u00e9s indik\u00e1l\u00e1s\u00e1ban \u00e9s e beavatkoz\u00e1sok ut\u00e1n a betegek k\u00f6vet\u00e9s\u00e9ben.<\/jats:p>","DOI":"10.1556\/oh.2009.28735","type":"journal-article","created":{"date-parts":[[2009,10,8]],"date-time":"2009-10-08T01:08:05Z","timestamp":1254964085000},"page":"1978-1982","source":"Crossref","is-referenced-by-count":0,"title":["The value of twenty-four hour intraoesophageal pH monitoring and manometry in the management of patients with upper gastrointestinal symptoms"],"prefix":"10.1556","volume":"150","author":[{"given":"Lilla","family":"Lakner","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Zolt\u00e1n","family":"D\u00f6br\u00f6nte","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"425","reference":[{"key":"atypb1","doi-asserted-by":"crossref","first-page":"173","DOI":"10.1159\/000081626","volume":"70","year":"2004","journal-title":"Digestion"},{"key":"atypb3","doi-asserted-by":"crossref","first-page":"24","DOI":"10.1159\/000200911","volume":"51","year":"1992","journal-title":"Digestion"},{"key":"atypb4","doi-asserted-by":"crossref","first-page":"17","DOI":"10.1159\/000076372","volume":"69","year":"2004","journal-title":"Digestion"},{"key":"atypb5","doi-asserted-by":"crossref","first-page":"9","DOI":"10.1159\/000076371","volume":"69","year":"2004","journal-title":"Digestion"},{"key":"atypb6","doi-asserted-by":"crossref","first-page":"1798","DOI":"10.1053\/gast.1997.v112.pm9178669","volume":"112","year":"1997","journal-title":"Gastroenterology"},{"key":"atypb8","doi-asserted-by":"crossref","first-page":"218","DOI":"10.1159\/000146083","volume":"77","year":"2008","journal-title":"Digestion"},{"key":"atypb9","doi-asserted-by":"crossref","first-page":"235","DOI":"10.1007\/s11894-008-0049-0","volume":"10","year":"2008","journal-title":"Curr. 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