{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2023,9,13]],"date-time":"2023-09-13T20:37:01Z","timestamp":1694637421143},"reference-count":45,"publisher":"Akademiai Kiado Zrt.","issue":"49","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2009,12,1]]},"abstract":"<jats:p>A m\u00e1j\u00e1t\u00fcltet\u00e9sek sz\u00e1m\u00e1t korl\u00e1tozza a be\u00fcltet\u00e9sre alkalmas donorszervek mennyis\u00e9ge. A szervhi\u00e1ny megold\u00e1s\u00e1ra az egyik lehet\u0151s\u00e9g az \u00fagynevezett margin\u00e1lis donorok (extended donor criteria) elfogad\u00e1sa a m\u00e1j\u00e1t\u00fcltet\u00e9si programban.<jats:italic>C\u00e9lkit\u0171z\u00e9s:<\/jats:italic>A magyar m\u00e1j\u00e1t\u00fcltet\u00e9si program szervdon\u00e1ci\u00f3s jellemz\u0151inek vizsg\u00e1lata, k\u00fcl\u00f6n\u00f6s tekintettel a margin\u00e1lis donorokra.<jats:italic>M\u00f3dszer:<\/jats:italic>Donor- \u00e9s recipiensadatok retrospekt\u00edv feldolgoz\u00e1sa 2003. janu\u00e1r \u00e9s 2008. december k\u00f6z\u00f6tt. A margin\u00e1lisdonor-krit\u00e9riumrendszert nemzetk\u00f6zi aj\u00e1nl\u00e1sok alapj\u00e1n \u00e1ll\u00edtottuk fel.<jats:italic>Eredm\u00e9nyek:<\/jats:italic>A vizsg\u00e1lt peri\u00f3dus alatt \u00f6sszesen 1078 donort jelentettek a klinik\u00e1n. Nyolcsz\u00e1zharminc\u00f6t esetben (77,4%) alkalmatlannak \u00edt\u00e9lt\u00e9k a donorm\u00e1jat a transzplant\u00e1ci\u00f3ra, 243 esetben (22,6%) volt be\u00fcltet\u00e9sre alkalmas a donorm\u00e1j. A be\u00fcltetett m\u00e1jgraftok k\u00f6z\u00fcl 40 (16%) sz\u00e1rmazott margin\u00e1lis, 203 (84%) nem margin\u00e1lis donorb\u00f3l. Margin\u00e1lis m\u00e1jgraftok be\u00fcltet\u00e9se eset\u00e9n nem volt k\u00fcl\u00f6nbs\u00e9g a beteg- \u00e9s graftt\u00fal\u00e9l\u00e9sben, a posztoperat\u00edv graftfunkci\u00f3t jelz\u0151 param\u00e9terekben \u00e9s az \u00e1ltal\u00e1nos sz\u00f6v\u0151dm\u00e9nyek gyakoris\u00e1g\u00e1ban. A korai hepatitis C-rekurrencia gyakoribb volt margin\u00e1lis graft be\u00fcltet\u00e9se eset\u00e9n.<jats:italic>K\u00f6vetkeztet\u00e9sek:<\/jats:italic>A m\u00e1j\u00e1t\u00fcltet\u00e9sre v\u00e1r\u00f3 betegek sz\u00e1ma haz\u00e1nkban is folyamatosan n\u00f6vekszik. Margin\u00e1lis m\u00e1jgraftok alkalmaz\u00e1sa eset\u00e9n a betegek morbidit\u00e1sa \u00e9s mortalit\u00e1sa nem k\u00fcl\u00f6nb\u00f6zik sz\u00e1mottev\u0151en a standard donorokb\u00f3l sz\u00e1rmaz\u00f3 m\u00e1jgraftok be\u00fcltet\u00e9se ut\u00e1n tapasztalt eredm\u00e9nyekt\u0151l. Hepatitis C-v\u00edrus eset\u00e9n nem javasolt margin\u00e1lis m\u00e1jgraft be\u00fcltet\u00e9se. A donorok fels\u0151 \u00e9letkori hat\u00e1r\u00e1nak kiterjeszt\u00e9se megfontoland\u00f3.<\/jats:p>","DOI":"10.1556\/oh.2009.28743","type":"journal-article","created":{"date-parts":[[2009,12,2]],"date-time":"2009-12-02T06:12:03Z","timestamp":1259734323000},"page":"2228-2236","source":"Crossref","is-referenced-by-count":5,"title":["The role of marginal donors in liver transplantation. 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