{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2022,4,12]],"date-time":"2022-04-12T17:30:14Z","timestamp":1649784614145},"reference-count":56,"publisher":"Akademiai Kiado Zrt.","issue":"1","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2010,1,1]]},"abstract":"<jats:p>A legut\u00f3bbi \u00e9vtizedek sor\u00e1n az iparosodott t\u00e1rsadalmakban folyamatosan emelkedik a diabetes \u00e9s az obesitas incidenci\u00e1ja, \u00e9s ezzel p\u00e1rhuzamosan egyre gyakrabban l\u00e9pnek fel alv\u00e1szavarok, r\u00f6videbb az alv\u00e1ssal t\u00f6lt\u00f6tt id\u0151, n\u0151 a kr\u00f3nikus alv\u00e1shi\u00e1ny gyakoris\u00e1ga. Egyre t\u00f6bb adat t\u00e1masztja al\u00e1 azt a felt\u00e9telez\u00e9st, amely szerint az elh\u00edz\u00e1s \u00e9s a cukorbetegs\u00e9g, valamint az alv\u00e1szavarok k\u00f6z\u00f6tt egy \u00f6nront\u00f3 k\u00f6r teremt kapcsolatot: az alv\u00e1s-\u00e9brenl\u00e9t zavarok hatnak az endokrin \u00e9s az anyagcsere-\u00e1llapotra, ugyanakkor a metabolikus elt\u00e9r\u00e9sek befoly\u00e1solj\u00e1k az alv\u00e1s szab\u00e1lyoz\u00e1s\u00e1t. Az alv\u00e1szavarok k\u00f6z\u00fcl az alv\u00e1sf\u00fcgg\u0151 l\u00e9gz\u00e9szavarok, azon bel\u00fcl is az obstrukt\u00edv alv\u00e1si apnoe mutat legink\u00e1bb \u00f6sszef\u00fcgg\u00e9st a k\u00f3ros sz\u00e9nhidr\u00e1t-anyagcser\u00e9vel. A cukorbetegekn\u00e9l magasabb az alv\u00e1si apnoe prevalenci\u00e1ja \u00e9s a k\u00f6z\u00e9ps\u00falyos, illetve s\u00falyos alv\u00e1si apno\u00e9ban szenved\u0151k ar\u00e1nya az \u00e1tlagpopul\u00e1ci\u00f3hoz k\u00e9pest. A centr\u00e1lis obesitas az alv\u00e1si apno\u00e9nak \u00e9s a cukorbetegs\u00e9gnek is fontos rizik\u00f3faktora, de az obesitast\u00f3l f\u00fcggetlen, k\u00f6zvetlen kapcsolatot is siker\u00fclt igazolni a diabetes \u00e9s az apnoe k\u00f6z\u00f6tt. A diabeteses neuropathia \u00e9s a metabolikus szindr\u00f3ma \u00f6sszef\u00fcgg\u00e9st mutat az apnoe el\u0151fordul\u00e1s\u00e1val \u00e9s s\u00falyoss\u00e1g\u00e1val. Kapcsolat mutathat\u00f3 ki az apno\u00e9s epiz\u00f3dok k\u00f6vetkezt\u00e9ben fell\u00e9p\u0151 intermitt\u00e1l\u00f3 hypoxia \u00e9s az inzulinrezisztencia k\u00f6z\u00f6tt, aminek k\u00f6vetkezt\u00e9ben megn\u0151het a diabetesrizik\u00f3, vagy a megl\u00e9v\u0151 diabetes glykaemi\u00e1s kontrollja romolhat. A diabetol\u00f3gus \u00e9s az alv\u00e1sdiagnosztik\u00e1ban j\u00e1rtas szakorvosok \u00f6sszehangolt, prevent\u00edv munk\u00e1j\u00e1val a betegek \u00e9letmin\u0151s\u00e9ge \u00e9s a betegs\u00e9g kimenetele jav\u00edthat\u00f3.<\/jats:p>","DOI":"10.1556\/oh.2010.28676","type":"journal-article","created":{"date-parts":[[2009,12,23]],"date-time":"2009-12-23T20:36:09Z","timestamp":1261600569000},"page":"8-16","source":"Crossref","is-referenced-by-count":4,"title":["Links between diabetes mellitus and sleep disorders: focusing on obstructive sleep apnea"],"prefix":"10.1556","volume":"151","author":[{"given":"Orsolya \u00c1gnes","family":"V\u00e9ber","sequence":"first","affiliation":[{"name":"1 Semmelweis Egyetem, \u00c1ltal\u00e1nos Orvostudom\u00e1nyi Kar I. 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