{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2022,4,4]],"date-time":"2022-04-04T18:46:18Z","timestamp":1649097978646},"reference-count":33,"publisher":"Akademiai Kiado Zrt.","issue":"33","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2010,8,1]]},"abstract":"<jats:p>A szepszishez t\u00e1rsul\u00f3 encephalopathia a sziszt\u00e9m\u00e1s gyullad\u00e1sos reakci\u00f3 korai szakasz\u00e1ban jelentkez\u0151, gyakori, de klinikai szempontb\u00f3l elhanyagolt t\u00fcnete. A sziszt\u00e9m\u00e1s szepszis okozta diff\u00faz agyi m\u0171k\u00f6d\u00e9szavar, \u00fajabb elnevez\u00e9s szerint a szepszishez t\u00e1rsul\u00f3 encephalopathia (sepsis-associated encephalopathy \u2013 SAE) v\u00e1ltozatos megjelen\u00e9s\u0171 lehet: az \u00e1tmeneti, reverz\u00edbilis encephalopathi\u00e1val jellemezhet\u0151 form\u00e1t\u00f3l eg\u00e9szen a visszaford\u00edthatatlan agyi k\u00e1rosod\u00e1ssal j\u00e1r\u00f3 s\u00falyos form\u00e1ig terjedhet a klinikai spektrum. A jelen k\u00f6zlem\u00e9nyben a hazai \u00e9s a nemzetk\u00f6zi szakirodalom \u00e1ttekint\u00e9se alapj\u00e1n \u00f6ssze k\u00edv\u00e1ntuk foglalni a k\u00f3rk\u00e9p k\u00f3r\u00e9lettani h\u00e1tter\u00e9t, a leggyakrabban el\u0151fordul\u00f3 klinikai t\u00fcneteket \u00e9s a kezel\u00e9s lehets\u00e9ges m\u00f3djait. Fel k\u00edv\u00e1ntuk h\u00edvni a figyelmet arra, hogy szepszisben a k\u00fcl\u00f6nb\u00f6z\u0151 s\u00falyoss\u00e1g\u00fa tudatzavar az egyik legkor\u00e1bbi figyelmeztet\u0151 t\u00fcnet, ez\u00e9rt a szepszis szempontj\u00e1b\u00f3l vesz\u00e9lyeztetett betegekben felismer\u00e9se nagy klinikai jelent\u0151s\u00e9g\u0171.<\/jats:p>","DOI":"10.1556\/oh.2010.28932","type":"journal-article","created":{"date-parts":[[2010,8,8]],"date-time":"2010-08-08T01:01:47Z","timestamp":1281229307000},"page":"1340-1346","source":"Crossref","is-referenced-by-count":0,"title":["Sepsis-associated encephalopathy"],"prefix":"10.1556","volume":"151","author":[{"given":"Szil\u00e1rd","family":"Szatm\u00e1ri","sequence":"first","affiliation":[{"name":"1 Debreceni Egyetem, Orvos- \u00e9s Eg\u00e9szs\u00e9gtudom\u00e1nyi Centrum Aneszteziol\u00f3giai \u00e9s Intenz\u00edv Ter\u00e1pi\u00e1s Tansz\u00e9k Debrecen M\u00f3ricz Zs. krt. 22. 4032"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Tam\u00e1s","family":"V\u00e9gh","sequence":"additional","affiliation":[{"name":"1 Debreceni Egyetem, Orvos- \u00e9s Eg\u00e9szs\u00e9gtudom\u00e1nyi Centrum Aneszteziol\u00f3giai \u00e9s Intenz\u00edv Ter\u00e1pi\u00e1s Tansz\u00e9k Debrecen M\u00f3ricz Zs. krt. 22. 4032"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Csaba","family":"Antek","sequence":"additional","affiliation":[{"name":"1 Debreceni Egyetem, Orvos- \u00e9s Eg\u00e9szs\u00e9gtudom\u00e1nyi Centrum Aneszteziol\u00f3giai \u00e9s Intenz\u00edv Ter\u00e1pi\u00e1s Tansz\u00e9k Debrecen M\u00f3ricz Zs. krt. 22. 4032"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Istv\u00e1n","family":"Tak\u00e1cs","sequence":"additional","affiliation":[{"name":"2 Debreceni Egyetem, Orvos- \u00e9s Eg\u00e9szs\u00e9gtudom\u00e1nyi Centrum Seb\u00e9szeti Int\u00e9zet Debrecen"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"P\u00e9ter","family":"S\u00edr\u00f3","sequence":"additional","affiliation":[{"name":"1 Debreceni Egyetem, Orvos- \u00e9s Eg\u00e9szs\u00e9gtudom\u00e1nyi Centrum Aneszteziol\u00f3giai \u00e9s Intenz\u00edv Ter\u00e1pi\u00e1s Tansz\u00e9k Debrecen M\u00f3ricz Zs. krt. 22. 4032"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"B\u00e9la","family":"F\u00fclesdi","sequence":"additional","affiliation":[{"name":"1 Debreceni Egyetem, Orvos- \u00e9s Eg\u00e9szs\u00e9gtudom\u00e1nyi Centrum Aneszteziol\u00f3giai \u00e9s Intenz\u00edv Ter\u00e1pi\u00e1s Tansz\u00e9k Debrecen M\u00f3ricz Zs. krt. 22. 4032"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"425","reference":[{"key":"atypb1","doi-asserted-by":"crossref","first-page":"474","DOI":"10.1097\/00003246-199005000-00002","volume":"18","year":"1990","journal-title":"Crit. 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