{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,9,29]],"date-time":"2025-09-29T03:55:15Z","timestamp":1759118115993},"reference-count":39,"publisher":"Akademiai Kiado Zrt.","issue":"23","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Orvosi Hetilap"],"published-print":{"date-parts":[[2013,6]]},"abstract":"<jats:p>Background: The prevalence of Helicobacter pylori infection in developed countries is decreasing. The time-frame of this process is largely unknown. Aim: The aim of the authors was to evaluate the changes in the prevalence of Helicobacter pylori infection in their endoscopic centre. Methods: This retrospective study included 4647 patients examined between 1997 and 2012. Helicobacter pylori was determined from antral and corpus biopsies by the modified Giemsa stain and rapid urease test. The prevalence of the infection was calculated yearly for the period studied, for age decades from 18 to 85 years, birth cohorts of 10 years from 1920 to 1994 and according to diagnosis. Results: The overall prevalence of Helicobacter pylori infection was 54.7%, which decreased from 71.3% in 1997 to 32.76% in 2011. Functional dyspepsia was found in 37.9%, duodenal ulcer in 25.3%, gastric ulcer in 3.8% and reflux disease in 24.2% of the patients. The mean prevalence of infection was 62.5% in birth cohorts of 10 years between 1920 and 1959, 57.4% in those between 1960 and 1969, and decreased to 39.0% and 26.7% in birth cohorts between 1970 and 1979) and between 1980 and 1989, respectively. According to age cohorts, the prevalence was 21.8% 34.9%, 46.5%, 63.7%, 63.2% and 59.2% in patients aged 18\u201319 years, 20\u201329 years, 30\u201339 years, 40\u201349 years, 50\u201359 years and 60\u201369 years, respectively. The proportion of H. pylori positive duodenal ulcers decreased from 95.9% in 1998 to 59.1% in 2011 (p = 0.001). Conclusions: The prevalence of Helicobacter pylori infection in the 9th district of Budapest is decreasing, especially in cohorts born in the late 1960s and 1970s, nearly 1.5 decades before the discovery of the bacterium. Orv. Hetil., 2013, 154, 900\u2013907.<\/jats:p>","DOI":"10.1556\/oh.2013.29630","type":"journal-article","created":{"date-parts":[[2013,6,3]],"date-time":"2013-06-03T01:00:52Z","timestamp":1370221252000},"page":"900-907","source":"Crossref","is-referenced-by-count":8,"title":["Changing prevalence of<i>Helicobacter pylori<\/i>infection in the 9th district of Budapest. A retrospective endoscopic study, 1997\u20132012"],"prefix":"10.1556","volume":"154","author":[{"given":"Gy\u00f6rgy Mikl\u00f3s","family":"Buz\u00e1s","sequence":"first","affiliation":[{"name":"Ferencv\u00e1rosi Eg\u00e9szs\u00e9g\u00fcgyi Szolg\u00e1lat KKNP Kft. Gasztroenterol\u00f3gia Budapest Mester u. 45. 1095"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"G\u00e1bor","family":"Lotz","sequence":"additional","affiliation":[{"name":"Semmelweis Egyetem, \u00c1ltal\u00e1nos Orvostudom\u00e1nyi Kar II. Patol\u00f3giai Int\u00e9zet Budapest"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ferenc","family":"Schneider","sequence":"additional","affiliation":[{"name":"Sejtdiagnosztika Kft. Budapest"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jol\u00e1n","family":"J\u00f3zan","sequence":"additional","affiliation":[{"name":"Semmelweis Egyetem, \u00c1ltal\u00e1nos Orvostudom\u00e1nyi Kar \u00c9lettani Int\u00e9zet Budapest"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"425","reference":[{"key":"atypb1","doi-asserted-by":"crossref","first-page":"54","DOI":"10.1093\/aje\/kwr288","volume":"175","year":"2012","journal-title":"Am. J. 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