{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2024,7,25]],"date-time":"2024-07-25T14:43:16Z","timestamp":1721918596909},"reference-count":13,"publisher":"Akademiai Kiado Zrt.","issue":"24","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Orvosi Hetilap"],"published-print":{"date-parts":[[2013,6]]},"abstract":"<jats:p> Introduction: Rational use of antibiotics is an important tool in combating antibiotic resistance. Aim: The aim of the authors was to evaluate the quality of ambulatory antibiotic use in Hungary. Method: Crude antibiotic sales data for the period between 1996 and 2010 were converted into DDD (Defined Daily Dose) per 1000 inhabitants and per year. The recently developed and validated drug-specific quality indicators were used to evaluate antibiotic use. Results: Beside constant quantity (18.0\u00b11.8 DDD\/1000 inhabitants\/day), the authors detected major changes in the composition of antibiotic use. Ratios of the consumption of broad to narrow spectrum beta-lactams and macrolides increased eight-fold (1996: 2.2 vs. 2010: 15.8) and consumption of fluoroquinolones tripled. Out of the ten surveyed drug-specific quality indicators, Hungary belonged to the European elite in case of three, while considering the remaining seven, Hungary ranked among the weak or weakest European countries. Conclusion: In quantity Hungary an ambulatory antibiotic use resembles to Scandinavian countries while it mimics antibiotic consumption patterns of southern countries. Orv. Hetil., 2013, 154, 947\u2013956. <\/jats:p>","DOI":"10.1556\/oh.2013.29632","type":"journal-article","created":{"date-parts":[[2013,6,11]],"date-time":"2013-06-11T01:05:28Z","timestamp":1370912728000},"page":"947-956","source":"Crossref","is-referenced-by-count":8,"title":["Evaluation of ambulatory antibiotic use in Hungary using drug-specific quality indicators"],"prefix":"10.1556","volume":"154","author":[{"given":"M\u00e1ria","family":"Matuz","sequence":"first","affiliation":[{"name":"Szegedi Tudom\u00e1nyegyetem, Gy\u00f3gyszer\u00e9sz-tudom\u00e1nyi Kar Klinikai Gy\u00f3gyszer\u00e9szeti Int\u00e9zet Szeged Szikra u. 8. 6725"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ria","family":"Benk\u0151","sequence":"additional","affiliation":[{"name":"Szegedi Tudom\u00e1nyegyetem, Gy\u00f3gyszer\u00e9sz-tudom\u00e1nyi Kar Klinikai Gy\u00f3gyszer\u00e9szeti Int\u00e9zet Szeged Szikra u. 8. 6725"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Edit","family":"Hajd\u00fa","sequence":"additional","affiliation":[{"name":"Szegedi Tudom\u00e1nyegyetem, Szent-Gy\u00f6rgyi Albert Klinikai K\u00f6zpont I. 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