{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,6,2]],"date-time":"2026-06-02T17:50:31Z","timestamp":1780422631372,"version":"3.54.1"},"reference-count":49,"publisher":"Akademiai Kiado Zrt.","issue":"40","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Orvosi Hetilap"],"published-print":{"date-parts":[[2013,10]]},"abstract":"<jats:p> Twin studies play a role in examining the contribution of genetic variations and environmental factors responsible for the determination of phenotypic variables and of genetic linkage between genotypes. Hungarian twin studies, supported by three twin registries (among them two twin-database), date back to 1970s. Studies mainly focused on various congenital abnormalities, the effect of contraceptive pills and folic acid on the frequency of twin pregnancies, as well as psychosexual and alcohol consumptional behaviors. Monogenic Mendelian inheritance of lactose (mal)absorption was demonstrated for the first time. Hungarian Twin Registry was founded in 2007, which contributed to the current understanding on the background of several disorders, e.g. metabolic syndrome and atherosclerosis. As part of an international twin study, among others, arterial stiffness, central blood pressure, carotid intima\/media thickness, venous biomechanics, body composition, lung function and smoking characteristics were also assessed. Absence of genetic background in non-alcoholic fatty liver disease and high inheritance of carotid plaque characteristics were demonstrated for the first time. The review also aims to summarize future plans of the Hungarian Twin Registry. Orv. Hetil., 2013, 154, 1579\u20131586. <\/jats:p>","DOI":"10.1556\/oh.2013.29707","type":"journal-article","created":{"date-parts":[[2013,9,30]],"date-time":"2013-09-30T01:09:36Z","timestamp":1380503376000},"page":"1579-1586","source":"Crossref","is-referenced-by-count":6,"title":["Hungarian twin studies: results of four decades"],"prefix":"10.1556","volume":"154","author":[{"given":"\u00c1d\u00e1m Domonkos","family":"T\u00e1rnoki","sequence":"first","affiliation":[{"name":"Semmelweis Egyetem, \u00c1ltal\u00e1nos Orvostudom\u00e1nyi Kar Radiol\u00f3giai \u00e9s Onkoter\u00e1pi\u00e1s Klinika Budapest \u00dcll\u0151i \u00fat 78\/A 1082"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"D\u00e1vid L\u00e1szl\u00f3","family":"T\u00e1rnoki","sequence":"additional","affiliation":[{"name":"Semmelweis Egyetem, \u00c1ltal\u00e1nos Orvostudom\u00e1nyi Kar Radiol\u00f3giai \u00e9s Onkoter\u00e1pi\u00e1s Klinika Budapest \u00dcll\u0151i \u00fat 78\/A 1082"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Tam\u00e1s","family":"Horv\u00e1th","sequence":"additional","affiliation":[{"name":"Bajcsy-Zsilinszky K\u00f3rh\u00e1z \u00e9s Rendel\u0151int\u00e9zet III. 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