{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,9,23]],"date-time":"2025-09-23T14:13:18Z","timestamp":1758636798064},"reference-count":15,"publisher":"Akademiai Kiado Zrt.","issue":"21","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Orvosi Hetilap"],"published-print":{"date-parts":[[2014,5]]},"abstract":"<jats:p>Compression of the rostral ventrolateral medulla oblongata is one of the rarely identified causes of refractory hypertension. In patients with severe, intractable hypertension caused by neurovascular compression, neurosurgical decompression should be considered. The authors present the history of a 20-year-old man with severe hypertension. After excluding other possible causes of secondary hypertension, the underlying cause of his high blood pressure was identified by the demonstration of neurovascular compression shown by magnetic resonance angiography and an increased sympathetic activity (sinus tachycardia) during the high blood pressure episodes. Due to frequent episodes of hypertensive crises, surgical decompression was recommended, which was performed with the placement of an isograft between the brainstem and the left vertebral artery. In the first six months after the operation, the patient\u2019s blood pressure could be kept in the normal range with significantly reduced doses of antihypertensive medication. Repeat magnetic resonance angiography confirmed the cessation of brainstem compression. After six months periodically increased blood pressure returned, but in smaller extent and less frequent. Based on the result of magnetic resonance angiography performed 22 months after surgery, re-operation was considerd. According to previous literature data long-term success can only be achieved in one third of patients after surgical decompression. In the majority of patients surgery results in a significant decrease of blood pressure, an increased efficiency of antihypertensive therapy as well as a decrease in the frequency of highly increased blood pressure episodes. Thus, a significant improvement of the patient\u2019s quality of life can be achieved. The case of this patient is an example of the latter scenario. Orv. Hetil., 2014, 155(21), 838\u2013842.<\/jats:p>","DOI":"10.1556\/oh.2014.29908","type":"journal-article","created":{"date-parts":[[2014,5,19]],"date-time":"2014-05-19T01:00:47Z","timestamp":1400461247000},"page":"838-842","source":"Crossref","is-referenced-by-count":1,"title":["Neurovascular compression of the medulla oblongata, case report. The rare cause of secondary hypertension"],"prefix":"10.1556","volume":"155","author":[{"given":"Judit","family":"N\u00e1das","sequence":"first","affiliation":[{"name":"Bajcsy-Zsilinszky K\u00f3rh\u00e1z III. Belgy\u00f3gy\u00e1szati Oktat\u00f3 Oszt\u00e1ly Budapest Magl\u00f3di \u00fat 89\u201391. 1106"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"S\u00e1ndor","family":"Czirj\u00e1k","sequence":"additional","affiliation":[{"name":"Orsz\u00e1gos Idegtudom\u00e1nyi Int\u00e9zet Budapest"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"P\u00e9ter","family":"Igaz","sequence":"additional","affiliation":[{"name":"Semmelweis Egyetem, \u00c1ltal\u00e1nos Orvostudom\u00e1nyi Kar II. Belgy\u00f3gy\u00e1szati Klinika Budapest"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Erika","family":"V\u00f6r\u00f6s","sequence":"additional","affiliation":[{"name":"Szegedi Tudom\u00e1nyegyetem, \u00c1ltal\u00e1nos Orvostudom\u00e1nyi Kar Radiol\u00f3giai Klinika Szeged"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Gy\u00f6rgy","family":"Jermendy","sequence":"additional","affiliation":[{"name":"Bajcsy-Zsilinszky K\u00f3rh\u00e1z III. Belgy\u00f3gy\u00e1szati Oktat\u00f3 Oszt\u00e1ly Budapest Magl\u00f3di \u00fat 89\u201391. 1106"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"K\u00e1roly","family":"R\u00e1cz","sequence":"additional","affiliation":[{"name":"Semmelweis Egyetem, \u00c1ltal\u00e1nos Orvostudom\u00e1nyi Kar II. 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M.:<\/i> Clinical observations on etiology of essential hypertension. Surg. Forum, 1979, <i>30,<\/i> 431\u2013432."},{"key":"4","doi-asserted-by":"crossref","unstructured":"<i>Gardner, W. J., Miklos, M. V.:<\/i> Response of trigeminal neuralgia to \u201cdecompression\u201d of sensory root. Discussion of cause of trigeminal neuralgia. J. Am. Med. Assoc., 1959, <i>170<\/i>(15), 1773\u20131776.","DOI":"10.1001\/jama.1959.03010150017004"},{"key":"5","doi-asserted-by":"crossref","unstructured":"<i>Pickering, T. G.:<\/i> Neurovascular compression of the medulla: can it cause neurogenic hypertension? J. Clin. Hypertens., 2007, <i>9<\/i>(1), 63\u201366.","DOI":"10.1111\/j.1524-6175.2007.05980.x"},{"key":"6","doi-asserted-by":"crossref","unstructured":"<i>Boogaarts, H. D., Menovsky, T., de Vries, J., et al.:<\/i> Primary hypertension and neurovascular compression: a meta-analysis of magnetic resonance imaging studies. J. 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