{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2023,10,2]],"date-time":"2023-10-02T21:22:56Z","timestamp":1696281776873},"reference-count":14,"publisher":"Akademiai Kiado Zrt.","issue":"29","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Orvosi Hetilap"],"published-print":{"date-parts":[[2014,7]]},"abstract":"<jats:p>Introduction: At present, there is no obligatory guideline for the prevention of early-onset neonatal group B streptococcal disease in Hungary. Aim: The aim of the present study was to gain insight into the spontaneously developed preventive strategy of the domestic obstetric divisions and departments in Hungary. Method: Standardized questionnaire was sent out to each of the 71 obstetric divisions and departments in Hungary. Results: Overall, 20 (27.4%) of the chairpersons replied, and thus, 39.9% of the total number of live births in Hungary were included in the study. Despite missing public health guidelines, each of the divisions and departments developed their own strategy to prevent neonatal group B streptococcal disease. In 95% of cases, bacterial culture of the lower vagina was the method of identifying pregnant women at risk. In 5% of the cases intrapartum antibiotic prophylaxis was based on risk assessment only. Of the departments using culture-based prophylaxis, 58% departments sampled women after completion of 36th gestational weeks. Antibiotic of choice was penicillin or ampicillin in 100% of cases. Of the study participants, 80% reported on multiple administration of colonized pregnant women after onset of labor or rupture of the membranes. Conclusions: The authors concluded that the rate of participation in the study was low. However, prevention of early-onset neonatal group B streptococcal infection is a priority of obstetric care in Hungary. Lack of a nation-wide public health policy did not prevent obstetric institutions in this country to develop their own prevention strategy. In the majority of cases and institutions, the policy is consistent with the widely accepted international standards. Orv. Hetil., 2014, 155(29), 1167\u20131172.<\/jats:p>","DOI":"10.1556\/oh.2014.29932","type":"journal-article","created":{"date-parts":[[2014,7,13]],"date-time":"2014-07-13T01:01:02Z","timestamp":1405213262000},"page":"1167-1172","source":"Crossref","is-referenced-by-count":1,"title":["Prevention of neonatal group B streptococcal sepsis in Hungary in 2012. Preliminary data of a nation-wide survey"],"prefix":"10.1556","volume":"155","author":[{"given":"Istv\u00e1n","family":"Sziller","sequence":"first","affiliation":[{"name":"Szent Imre Egyetemi Oktat\u00f3k\u00f3rh\u00e1z Sz\u00fcl\u00e9szeti \u00e9s N\u0151gy\u00f3gy\u00e1szati Oszt\u00e1ly Budapest T\u00e9t\u00e9nyi \u00fat 12\u201316. 1115"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Mikl\u00f3s","family":"Szab\u00f3","sequence":"additional","affiliation":[{"name":"Semmelweis Egyetem, \u00c1ltal\u00e1nos Orvostudom\u00e1nyi Kar I. Gyermekklinika Budapest"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Andrea","family":"Valek","sequence":"additional","affiliation":[{"name":"Orsz\u00e1gos Csecsem\u0151- \u00e9s Gyermekeg\u00e9szs\u00e9g\u00fcgyi Int\u00e9zet Budapest"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Barbara","family":"Rig\u00f3","sequence":"additional","affiliation":[{"name":"Maternity Sz\u00fcl\u00e9szeti \u00e9s N\u0151gy\u00f3gy\u00e1szati Mag\u00e1nklinika Budapest"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"N\u00e1ndor","family":"\u00c1cs","sequence":"additional","affiliation":[{"name":"Semmelweis Egyetem, \u00c1ltal\u00e1nos Orvostudom\u00e1nyi Kar II. Sz\u00fcl\u00e9szeti \u00e9s N\u0151gy\u00f3gy\u00e1szati Klinika Budapest"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"425","reference":[{"key":"1","doi-asserted-by":"crossref","unstructured":"<i>Schuchat, A.:<\/i> Group B streptococcus. Lancet, 1999, <i>353<\/i>(9146), 51\u201356.","DOI":"10.1016\/S0140-6736(98)07128-1"},{"key":"2","doi-asserted-by":"crossref","unstructured":"<i>Boyer, K. M., Gadzala, C. A., Kelly, P. D., et al.:<\/i> Selective intrapartum chemoprophylaxis of neonatal group B streptococcal early-onset disease. III. Interruption of mother-to-infant transmission. J. Infect. Dis., 1983, <i>148<\/i>(5), 810\u2013816.","DOI":"10.1093\/infdis\/148.5.810"},{"key":"3","unstructured":"<i>Verani, J. R., McGee, L., Schrag, S. J.; Division of Bacterial Diseases, National Center for Immunization and Respiratory Diseases, Centers for Disease Control and Prevention (CDC):<\/i> Prevention of perinatal group B streptococcal disease \u2013 revised guidelines from CDC, 2010. MMWR Recomm. Rep., 2010, <i>59<\/i>(RR-10), 1\u201336."},{"key":"4","doi-asserted-by":"crossref","unstructured":"<i>Critchfield, A. S., Lievense, S. P., Raker, C. A., et al.:<\/i> Group B streptococcus prophylaxis in patients who report a penicillin allergy: a follow-up study. Am. J. Obstet. Gynecol., 2011, <i>204<\/i>(2), 150.e1\u2013150.e8.","DOI":"10.1016\/j.ajog.2010.08.063"},{"key":"5","doi-asserted-by":"crossref","unstructured":"<i>Schrag, S. J., Zell, E. R., Lynfield, R., et al.:<\/i> A population-based comparison of strategies to prevent early-onset group B streptococcal disease in neonates. N. Engl. J. Med., 2002, <i>347<\/i>(4), 233\u2013239.","DOI":"10.1056\/NEJMoa020205"},{"key":"6","doi-asserted-by":"crossref","unstructured":"<i>Lin, F. Y., Brenner, R. A., Johnson, Y. R., et al.:<\/i> The effectiveness of risk-based intrapartum chemoprophylaxis for the prevention of early-onset neonatal group B streptococcal disease. Am. J. Obstet. Gynecol., 2001, <i>184<\/i>(6), 1204\u20131210.","DOI":"10.1067\/mob.2001.113875"},{"key":"7","unstructured":"<i>Shah, V., Ohlsson, A.:<\/i> With the Canadian Task Force on Preventive Health Care: Prevention of early-onset group B streptococcal (GBS) infection in the newborn. Systematic review and recommendations. (CTFPHC) Technical Report 01-6. May, 2001. Canadian Task Force, London, ON, Canada, 2001."},{"key":"8","unstructured":"<i>Royal College of Obstetricians and Gynaecologists (RCOG):<\/i> Prevention of early onset neonatal group B streptococcal disease. RCOG Green-top Guideline, No. 36. July 2012. <a href=\"http:\/\/www.rcog.org.uk\/files\/rcog-corp\/GTG36_GBS.pdf\">http:\/\/www.rcog.org.uk\/files\/rcog-corp\/GTG36_GBS.pdf<\/a>"},{"key":"9","doi-asserted-by":"crossref","unstructured":"<i>Fairlie, T., Zell, E. R., Schrag, S.:<\/i> Effectiveness of intrapartum antibiotic prophylaxis for prevention of early-onset group B streptococcal disease. Obstet. Gynecol., 2013, <i>121<\/i>(3), 570\u2013577.","DOI":"10.1097\/AOG.0b013e318280d4f6"},{"key":"10","doi-asserted-by":"crossref","unstructured":"<i>Stoll, B. J., Hansen, N. I., S\u00e1nchez, P. J., et al.:<\/i> Early onset neonatal sepsis: the burden of group B streptococcal and E. coli disease continues. Pediatrics, 2011, <i>127<\/i>(5), 817\u2013826.","DOI":"10.1542\/peds.2010-2217d"},{"key":"11","unstructured":"<i>Papp, Z. (ed.):<\/i> Textbook of obstetrics and gynecology. 4th edition. [A sz\u00fcl\u00e9szet-n\u0151gy\u00f3gy\u00e1szat tank\u00f6nyve. Negyedik kiad\u00e1s.] Medicina K\u00f6nyvkiad\u00f3, Budapest, 2009. [Hungarian]"},{"key":"12","unstructured":"<i>Sziller, I., Bard\u00f3czy, Zs., Moln\u00e1r, Gy., et al.:<\/i> Sexually transmitted infection and preterm birth. [Szexu\u00e1lis \u00faton terjed\u0151 fert\u0151z\u00e9sek \u00e9s korasz\u00fcl\u00e9s.] Magy. Venerol. Arch., 1997, <i>1<\/i>(3), 7\u201311. [Hungarian]"},{"key":"13","doi-asserted-by":"crossref","unstructured":"<i>Horv\u00e1th, B., Grasselly, M., B\u00f6decs, T., et al.:<\/i> Screening pregnant women for group B streptococcus infection between 30 and 32 weeks of pregnancy in a population at high risk for premature birth. Int. J. Gynaecol. Obstet., 2013, <i>122<\/i>(1), 9\u201312.","DOI":"10.1016\/j.ijgo.2013.01.027"},{"key":"14","unstructured":"<i>Horv\u00e1th, B., Grasselly, M., Lakatos, F., et al.:<\/i> Intrapartum chemoprophylaxis to colonized patients with labor complications for group B streptococcal (GBS) neonatal infection. [Sz\u00fcl\u00e9s alatt alkalmazott antibiotikus kezel\u00e9s az \u00fajsz\u00fcl\u00f6ttkori B csoport\u00fa Streptococcus fert\u0151z\u00e9sek megel\u0151z\u00e9s\u00e9re.] Orv. Hetil., 1998, <i>139<\/i>(48), 2899\u20132901. 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