{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2024,7,6]],"date-time":"2024-07-06T00:18:24Z","timestamp":1720225104897},"reference-count":0,"publisher":"Codon Publications","issue":"4","license":[{"start":{"date-parts":[[2024,7,1]],"date-time":"2024-07-01T00:00:00Z","timestamp":1719792000000},"content-version":"unspecified","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Allergol Immunopathol"],"abstract":"<jats:p>Background:\u00a0Dermatophagoides pteronyssinus\u00a0and\u00a0Dermatophagoides farinae\u00a0belong to the family\u00a0Pyroglyphidae\u00a0(subfamily: \u201cDermatophagoidinae\u201d) and have the respective allergenic proteins of Der p1, Der p2, and Der p23 and Der f1 and Der f2.\u00a0Euroglyphus maynei, belongs to the family\u00a0Pyroglyphidae\u00a0(subfamily: \u201cPyroglyphinae\u201d) and its main allergenic protein is Eur m1, a source of sensitization. Sensitization to\u00a0D. pteronyssinus\u00a0and\u00a0D. farinae\u00a0is assessed through skin tests, while sensitization to\u00a0E. maynei\u00a0is assessed less frequently.\nObjective: This experimental work aims to analyze the prevalence of sensitization to\u00a0E. maynei\u00a0in patients with respiratory allergies treated at M. Albanesi Allergy and Immunology Unit in Bari, Italy, and the sequence homology of major allergenic proteins of\u00a0E. maynei\u00a0with\u00a0D. farinae\u00a0and\u00a0D. pteronyssinus\u00a0was analyzed.\nMethods: In this real-life study, 65 patients were enrolled. In particular, patients with respiratory allergy were subjected to skin prick tests for common respiratory allergens, including\u00a0Euroglyphus maynei. The sequence homology analysis was performed between the major allergenic proteins of\u00a0E. maynei\u00a0and those of\u00a0D. pteronyssinus\u00a0and\u00a0D. farinae.\nResults: Sensitization to\u00a0E. maynei\u00a0accounts for 41.5% of patients. All patients with\u00a0E. maynei\u00a0sensitization had concomitant sensitization to\u00a0D. farinae\u00a0and\u00a0D. pteronyssinus. The analysis of sequence homology of Der p1 and Der f1 proteins with the sequence of Eur m1 protein demonstrated an identity of 84.4% and 86%, respectively.\nConclusions: Nearly 50% of house dust mites-sensitized patients have a concomitant sensitization to\u00a0E. maynei. The cross-sensitization could be due to Der f1, Der p1, and Eur m1 similarity.<\/jats:p>","DOI":"10.15586\/aei.v52i4.1089","type":"journal-article","created":{"date-parts":[[2024,7,1]],"date-time":"2024-07-01T14:40:22Z","timestamp":1719844822000},"page":"1-8","source":"Crossref","is-referenced-by-count":0,"title":["Frequency of\u00a0Euroglyphus maynei\u00a0sensitization in respiratory allergies: a real-life study with bioinformatic analysis and geographical exploration of allergen prevalence"],"prefix":"10.15586","volume":"52","author":[{"given":"Stefano","family":"Palazzo","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Alessandro","family":"Cinquantasei","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Concetta","family":"De Chirico","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Marco","family":"Zurlo","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Vincenzo","family":"Aresta","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Nada","family":"Chaoul","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Marcello","family":"Albanesi","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"6228","published-online":{"date-parts":[[2024,7,1]]},"container-title":["Allergologia et Immunopathologia"],"original-title":[],"link":[{"URL":"https:\/\/www.all-imm.com\/index.php\/aei\/article\/download\/1089\/1593","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/www.all-imm.com\/index.php\/aei\/article\/download\/1089\/1594","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/www.all-imm.com\/index.php\/aei\/article\/download\/1089\/1595","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/www.all-imm.com\/index.php\/aei\/article\/download\/1089\/1593","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2024,7,5]],"date-time":"2024-07-05T07:09:19Z","timestamp":1720163359000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.all-imm.com\/index.php\/aei\/article\/view\/1089"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2024,7,1]]},"references-count":0,"journal-issue":{"issue":"4","published-online":{"date-parts":[[2024,7,1]]}},"URL":"https:\/\/doi.org\/10.15586\/aei.v52i4.1089","relation":{},"ISSN":["0301-0546"],"issn-type":[{"value":"0301-0546","type":"electronic"}],"subject":[],"published":{"date-parts":[[2024,7,1]]}}}