{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,11,25]],"date-time":"2025-11-25T06:07:32Z","timestamp":1764050852806,"version":"3.45.0"},"reference-count":10,"publisher":"Journal of the ASEAN Federation of Endocrine Societies (JAFES)","issue":"2","license":[{"start":{"date-parts":[[2025,11,7]],"date-time":"2025-11-07T00:00:00Z","timestamp":1762473600000},"content-version":"unspecified","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc\/4.0"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["J ASEAN Fed Endocr Soc"],"abstract":"<jats:p>Reninoma is a rare cause of renin-induced hypertension commonly seen in young adults and adolescents. Here, we describe a case of reninoma presenting with hypertension in the young. Further investigation revealed elevated renin and aldosterone levels. Computed tomography of the kidneys showed a right-sided renal mass. A diagnosis of reninoma was made, and the patient underwent nephron-sparing surgery, which rendered her normotensive post-operatively.<\/jats:p>","DOI":"10.15605\/jafes.040.02.20","type":"journal-article","created":{"date-parts":[[2025,11,25]],"date-time":"2025-11-25T05:59:00Z","timestamp":1764050340000},"page":"165-168","source":"Crossref","is-referenced-by-count":0,"title":["Reninoma"],"prefix":"10.15605","volume":"40","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-8514-7604","authenticated-orcid":false,"given":"Gaayathri","family":"Krishnan","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Lim Jing","family":"Li","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Tee Hwee","family":"Ching","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-7918-0929","authenticated-orcid":false,"given":"Serena","family":"Khoo","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"6244","published-online":{"date-parts":[[2025,11,7]]},"reference":[{"key":"79247","doi-asserted-by":"crossref","unstructured":"1. Wang B, Ding L, Xu S, et al. A case of atypical reninoma with mild hypertension and normal plasma renin activity but elevated plasma renin concentration. BMC Endocr Disord. 2022;22(1):71. https:\/\/pubmed.ncbi.nlm.nih.gov\/35303838 https:\/\/pmc.ncbi.nlm.nih.gov\/articles\/PMC8932068 https:\/\/doi.org\/10.1186\/s12902-022-00977-w","DOI":"10.1186\/s12902-022-00977-w"},{"key":"79249","doi-asserted-by":"crossref","unstructured":"2. Wong L, Hsu TH, Perlroth MG, Hofmann LV, Haynes CM, Katznelson L. Reninoma: Case report and literature review. J Hypertens. 2008;26(2):368-73. https:\/\/pubmed.ncbi.nlm.nih.gov\/18192852 https:\/\/doi.org\/10.1097\/HJH.0b013e3282f283f3","DOI":"10.1097\/HJH.0b013e3282f283f3"},{"key":"79251","doi-asserted-by":"crossref","unstructured":"3. Shera AH, Baba AA, Bakshi IH, Lone IA. Recurrent malignant juxtaglomerular cell tumor: A rare cause of malignant hypertension in a child. J Indian Assoc Pediatr Surg. 2011;16(4):152-4. https:\/\/pubmed.ncbi.nlm.nih.gov\/22121315 https:\/\/pmc.ncbi.nlm.nih.gov\/articles\/PMC3221159 https:\/\/doi.org\/10.4103\/0971-9261.86876","DOI":"10.4103\/0971-9261.86876"},{"key":"79253","doi-asserted-by":"crossref","unstructured":"4. Diker-Cohen T, Abraham SB, Rauschecker M, et al. Reninoma presenting in pregnancy. J Clin Endocrinol Metab. 2014;99(8):2625-6. https:\/\/pubmed.ncbi.nlm.nih.gov\/24848711 https:\/\/pmc.ncbi.nlm.nih.gov\/articles\/PMC4121021 https:\/\/doi.org\/10.1210\/jc.2014-1730","DOI":"10.1210\/jc.2014-1730"},{"key":"79255","doi-asserted-by":"crossref","unstructured":"5. Bealer SL. Systemic angiotensin II alters intrinsic heart rate through central mechanisms. Brain Res Bull. 2002;58(1):61-5. https:\/\/pubmed.ncbi.nlm.nih.gov\/12121814 https:\/\/doi.org\/10.1016\/s0361-9230(02)00756-6","DOI":"10.1016\/S0361-9230(02)00756-6"},{"key":"79257","doi-asserted-by":"crossref","unstructured":"6. Rosei CA, Giacomelli L, Salvetti M, et al. Advantages of renin inhibition in a patient with reninoma. Int J Cardiol. 2015;187:240-2. https:\/\/pubmed.ncbi.nlm.nih.gov\/25838223 https:\/\/doi.org\/10.1016\/j.ijcard.2015.03.280","DOI":"10.1016\/j.ijcard.2015.03.280"},{"key":"79259","doi-asserted-by":"crossref","unstructured":"7. Liu K, Wang B, Ma X, et al. Minimally invasive surgery-based multidisciplinary clinical management of reninoma: A single-center study. Med Sci Monit. 2019;25:1600-10. https:\/\/pubmed.ncbi.nlm.nih.gov\/30822300 https:\/\/pmc.ncbi.nlm.nih.gov\/articles\/PMC6407327 https:\/\/doi.org\/10.12659\/MSM.913826","DOI":"10.12659\/MSM.913826"},{"key":"79261","doi-asserted-by":"crossref","unstructured":"8. Wolley M, Gordon RD, Stowasser M. Reninoma: The importance of renal vein renin ratios for lateralisation and diagnosis. Am J Nephrol. 2014;39(1):16-9. https:\/\/pubmed.ncbi.nlm.nih.gov\/24401674 https:\/\/doi.org\/10.1159\/000357410","DOI":"10.1159\/000357410"},{"key":"79263","doi-asserted-by":"crossref","unstructured":"9. Vidal-Petiot E, Bens M, Choudat L, et al. A case report of reninoma: Radiological and pathological features of the tumour and characterization of tumour-derived juxtaglomerular cells in culture. J Hypertens. 2015;33(8):1709-15. https:\/\/pubmed.ncbi.nlm.nih.gov\/26132761 https:\/\/doi.org\/10.1097\/HJH.0000000000000592.","DOI":"10.1097\/HJH.0000000000000592"},{"key":"79265","doi-asserted-by":"crossref","unstructured":"10. Zhang R, Xu M, Xie XY. The role of real-time contrast-enhanced ultrasound in guiding radiofrequency ablation of reninoma: Case report and literature review. Front Oncol. 2021;11:585257. https:\/\/pubmed.ncbi.nlm.nih.gov\/33686368 https:\/\/pmc.ncbi.nlm.nih.gov\/articles\/PMC7935754 https:\/\/doi.org\/10.3389\/fonc.2021.585257","DOI":"10.3389\/fonc.2021.585257"}],"container-title":["Journal of the ASEAN Federation of Endocrine Societies"],"original-title":[],"link":[{"URL":"https:\/\/asean-endocrinejournal.org\/index.php\/JAFES\/article\/download\/4941\/5295","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/asean-endocrinejournal.org\/index.php\/JAFES\/article\/download\/4941\/5295","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,11,25]],"date-time":"2025-11-25T05:59:04Z","timestamp":1764050344000},"score":1,"resource":{"primary":{"URL":"https:\/\/asean-endocrinejournal.org\/index.php\/JAFES\/article\/view\/4941"}},"subtitle":["A Rare Cause of Surgically Curable Hypertension and Secondary Hyperaldosteronism"],"short-title":[],"issued":{"date-parts":[[2025,11,7]]},"references-count":10,"journal-issue":{"issue":"2","published-online":{"date-parts":[[2025,11,21]]}},"URL":"https:\/\/doi.org\/10.15605\/jafes.040.02.20","relation":{},"ISSN":["2308-118X","0857-1074"],"issn-type":[{"type":"electronic","value":"2308-118X"},{"type":"print","value":"0857-1074"}],"subject":[],"published":{"date-parts":[[2025,11,7]]}}}