{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,28]],"date-time":"2026-08-28T08:21:47Z","timestamp":1787905307680,"version":"build-2784847793"},"reference-count":9,"publisher":"Journal of the ASEAN Federation of Endocrine Societies (JAFES)","issue":"2","license":[{"start":{"date-parts":[[2026,8,22]],"date-time":"2026-08-22T00:00:00Z","timestamp":1787356800000},"content-version":"unspecified","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc\/4.0"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["J ASEAN Fed Endocr Soc"],"abstract":"<jats:p>Recurrent syncope and behavioral changes in the older population may suggest several disease entities associated with aging. Hypoglycemia is an often-missed potentially correctable underlying cause that should also be considered in the differential diagnosis. We present a case of a 62-year-old Filipino woman who presented with recurrent syncopal attacks, behavioral changes and unintentional weight gain, associated with endogenous hyperinsulinemic hypoglycemia with no pancreatic mass seen on abdominal CT scan. A pancreatic head tumor was visualized through endoscopic ultrasound. Surgical removal of the mass resulted in resolution of her symptoms and restoration of her physical and functional well-being. This case is being reported to highlight that surgery cured her of the disease and she remains asymptomatic and well 13 years after her surgery.<\/jats:p>","DOI":"10.15605\/jafes.041.02.6285","type":"journal-article","created":{"date-parts":[[2026,8,28]],"date-time":"2026-08-28T08:16:05Z","timestamp":1787904965000},"source":"Crossref","is-referenced-by-count":0,"title":["Recurrent Syncope, Behavioral Changes and Weight Gain in an Elderly Filipino Woman"],"prefix":"10.15605","volume":"41","author":[{"given":"Edwin","family":"Canete","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mark Anthony","family":"Sandoval","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"6244","published-online":{"date-parts":[[2026,8,22]]},"reference":[{"key":"86915","unstructured":"1. Vaidakis D, Karoubalis J, Pappa T, Piaditis G, Zografos GN. Pancreatic insulinoma: Current issues and trends. Hepatobiliary Pancreat Dis Int. 2010;9(3):234-41. https:\/\/pubmed.ncbi.nlm.nih.gov\/20525548"},{"key":"86916","doi-asserted-by":"crossref","unstructured":"2. Service FJ, McMahon MM, O'Brien PC, Ballard DJ. Functioning insulinoma \u2013 incidence, recurrence, and long-term survival of patients: A 60-year study. Mayo Clin Proc. 1991;66(7):711-9. https:\/\/pubmed.ncbi.nlm.nih.gov\/1677058 DOI: 10.1016\/s0025-6196(12)62083-7","DOI":"10.1016\/S0025-6196(12)62083-7"},{"key":"86917","unstructured":"3. Boukhman MP, Karam JH, Shaver J, Siperstein AE, Duh QY, Clark OH. Insulinoma \u2013 experience from 1950 to 1995. West J Med. 1998;169(2):98-104. https:\/\/pubmed.ncbi.nlm.nih.gov\/9735690 https:\/\/www.ncbi.nlm.nih.gov\/pmc\/articles\/PMC1305178"},{"key":"86918","doi-asserted-by":"crossref","unstructured":"4. Cryer PE, Axelrod L, Grossman AB, et al. Evaluation and management of adult hypoglycemic disorders: An Endocrine Society Clinical Practice Guideline. J Clin Endocrinol Metab. 2009;94(3):709-28. https:\/\/pubmed.ncbi.nlm.nih.gov\/19088155 https:\/\/doi.org\/10.1210\/jc.2008-1410","DOI":"10.1210\/jc.2008-1410"},{"key":"86919","unstructured":"5. Giannis D, Moris D, Karachaliou GS, et al. Insulinomas: From diagnosis to treatment. A review of the literature. J BUON. 2020;25(3):1302-14. https:\/\/pubmed.ncbi.nlm.nih.gov\/32862570"},{"key":"86920","doi-asserted-by":"crossref","unstructured":"6. Christ E, Antwi K, Fani M, Wild D. Innovative imaging of insulinoma: The end of sampling? A review. Endocr Relat Cancer. 2020;27(4):R79-92. https:\/\/pubmed.ncbi.nlm.nih.gov\/31951592 https:\/\/www.ncbi.nlm.nih.gov\/pmc\/articles\/PMC7040495 https:\/\/doi.org\/10.1530\/ERC-19-0476","DOI":"10.1530\/ERC-19-0476"},{"key":"86921","doi-asserted-by":"crossref","unstructured":"7. Alogakos M, Nakanishi H, Athanasiadis DI, et al. Enucleation for insulinoma: Consolidating evidence through systematic review and meta-analysis. Surg Endosc. 2025;39(10):6352-65. https:\/\/pubmed.ncbi.nlm.nih.gov\/40897878 https:\/\/www.ncbi.nlm.nih.gov\/pmc\/articles\/PMC12500762 https:\/\/doi.org\/10.1007\/s00464-025-12099-0","DOI":"10.1007\/s00464-025-12099-0"},{"key":"86922","doi-asserted-by":"crossref","unstructured":"8. Topsakal \u015e, Yaylal\u0131 GF, Yarar Z, et al. Multicenter study on the clinical characteristics, diagnosis, and treatment outcomes of insulinoma: Insights from 15 medical centres. Clin Endocrinol. 2025;103(1):57-65. https:\/\/pubmed.ncbi.nlm.nih.gov\/40275816 https:\/\/www.ncbi.nlm.nih.gov\/pmc\/articles\/PMC12134450 https:\/\/doi.org\/10.1111\/cen.15255","DOI":"10.1111\/cen.15255"},{"key":"86923","doi-asserted-by":"crossref","unstructured":"9. Peltola E, Hannula P, Huhtala H, et al. Long-term morbidity and mortality in patients diagnosed with an insulinoma. Eur J Endocrinol. 2021;185(4):577-586. https:\/\/pubmed.ncbi.nlm.nih.gov\/34374651 https:\/\/www.ncbi.nlm.nih.gov\/pmc\/articles\/PMC8784472 https:\/\/doi.org\/10.1530\/EJE-21-0230","DOI":"10.1530\/EJE-21-0230"}],"container-title":["Journal of the ASEAN Federation of Endocrine Societies"],"original-title":[],"link":[{"URL":"https:\/\/asean-endocrinejournal.org\/index.php\/JAFES\/article\/download\/6285\/5351","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/asean-endocrinejournal.org\/index.php\/JAFES\/article\/download\/6285\/5351","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,8,28]],"date-time":"2026-08-28T08:16:10Z","timestamp":1787904970000},"score":1,"resource":{"primary":{"URL":"https:\/\/asean-endocrinejournal.org\/index.php\/JAFES\/article\/view\/6285"}},"subtitle":["Successful Diagnosis and Management of Insulinoma With 13-Year Disease-Free Follow-up"],"short-title":[],"issued":{"date-parts":[[2026,8,22]]},"references-count":9,"journal-issue":{"issue":"2","published-online":{"date-parts":[[2026,8,6]]}},"URL":"https:\/\/doi.org\/10.15605\/jafes.041.02.6285","relation":{},"ISSN":["2308-118X","0857-1074"],"issn-type":[{"value":"2308-118X","type":"electronic"},{"value":"0857-1074","type":"print"}],"subject":[],"published":{"date-parts":[[2026,8,22]]}}}