{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,31]],"date-time":"2026-08-31T21:38:12Z","timestamp":1788212292506,"version":"build-2803163510"},"reference-count":53,"publisher":"American Academy of Implant Dentistry","issue":"5","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2015,10]]},"abstract":"\n The purpose of this study was to compare the efficacy between the use of bovine bone graft material and platelet-rich fibrin (PRF) mixture (test group) and bovine bone graft material and collagen membrane combination (control group) in 2-stage maxillary sinus augmentation. According to specific inclusion\/exclusion criteria, patients treated between 2008 and 2012 were selected. Panoramic radiographs were used for radiologic assessments. To evaluate the relationship between sinus-graft height and each implant, the bone level (BL) was divided by implant length (IL). To evaluate the change in the height of grafted sinus, the grafted sinus floor above the lowest part of the original sinus height (GSH) was divided by the original sinus height (OSH). Samples taken during implant surgery were used for histologic and histomorphometric analyses. Twenty-five patients, 32 augmentation surgeries, and 66 one-stage implants were included in the study. No implant loss or complication was observed in either group. There were no statistical differences according to new bone formation (\n P<\/jats:italic>\n = .61) and biomaterial remnant (\n P<\/jats:italic>\n = .87). During the evaluation period, the test group showed statistically less change in the BL\/IL ratio (\n P<\/jats:italic>\n = .022). The difference of GSH\/OSH ratio was found to be insignificant between groups (\n P<\/jats:italic>\n = .093). It was observed that the grafted sinus covering the implant apex and sinus floor was above the original sinus height in both groups. It may be concluded from this study that both combinations can be successfully used for sinus augmentation. Further studies evaluating different graft materials and PRF combinations in the early phases of healing would be beneficial.\n <\/jats:p>","DOI":"10.1563\/aaid-joi-d-13-00129","type":"journal-article","created":{"date-parts":[[2013,9,16]],"date-time":"2013-09-16T15:06:26Z","timestamp":1379343986000},"page":"586-595","source":"Crossref","is-referenced-by-count":45,"title":["Sinus Augmentation With Platelet-Rich Fibrin in Combination With Bovine Bone Graft Versus Bovine Bone Graft in Combination With Collagen Membrane"],"prefix":"10.1563","volume":"41","author":[{"given":"Nilufer","family":"Bolukbasi","sequence":"first","affiliation":[{"name":"Department of Oral Implantology, Faculty of Dentistry, Istanbul University, Istanbul, Turkey."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Selim","family":"Ersanl\u0131","sequence":"additional","affiliation":[{"name":"Department of Oral Implantology, Faculty of Dentistry, Istanbul University, Istanbul, Turkey."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Nurullah","family":"Keklikoglu","sequence":"additional","affiliation":[{"name":"Department of Histology and Embryology, Istanbul University, Istanbul, Turkey."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Cansu","family":"Basegmez","sequence":"additional","affiliation":[{"name":"Department of Oral Implantology, Faculty of Dentistry, Istanbul University, Istanbul, Turkey."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Tayfun","family":"Ozdemir","sequence":"additional","affiliation":[{"name":"Department of Oral Implantology, Faculty of Dentistry, Istanbul University, Istanbul, Turkey."}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"434","reference":[{"issue":"suppl 1","key":"i1548-1336-41-5-586-b01","series-title":"Clin Implant Dent Relat Res","first-page":"S104","article-title":"Short implants in the severely resorbed maxilla: a 2-year retrospective study","volume":"7","author":"Renouard\n F,","year":"2005","unstructured":"Renouard\n F, \n \n Nisand\n D.\n \n \n Short implants in the severely resorbed maxilla: a 2-year retrospective study. 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J Thromb Haemost. 2005;3:1894\u20131904."},{"key":"i1548-1336-41-5-586-b39","series-title":"J Indian Soc Periodontol","first-page":"108","article-title":"Use of platelet rich fibrin in a fenestration defect around an implant","volume":"16","author":"Vijayalakshmi\n R,","year":"2012","unstructured":"Vijayalakshmi\n R, \n \n Rajmohan\n CS, \n \n Deepalakshmi\n D, \n \n Sivakami\n G.\n \n \n Use of platelet rich fibrin in a fenestration defect around an implant. J Indian Soc Periodontol. 2012;16:108\u2013112."},{"key":"i1548-1336-41-5-586-b40","series-title":"Part III: leucocyte activation: a new feature for platelet concentrates? Oral Surg Oral Med Oral Pathol Oral Radiol Endod","first-page":"e51","article-title":"Platelet-rich fibrin (PRF): a second-generation platelet concentrate","volume":"101","author":"Dohan\n DM,","year":"2006","unstructured":"Dohan\n DM, \n \n Choukroun\n J, \n \n Diss\n A, \n et al\n . Platelet-rich fibrin (PRF): a second-generation platelet concentrate. Part III: leucocyte activation: a new feature for platelet concentrates? Oral Surg Oral Med Oral Pathol Oral Radiol Endod. 2006;101:e51\u2013e55."},{"key":"i1548-1336-41-5-586-b41","series-title":"Growth Factors","first-page":"63","article-title":"Slow release of growth factors and thrombospondin-1 in Choukroun's platelet-rich fibrin (PRF): a gold standard to achieve for all surgical platelet concentrates technologies","volume":"27","year":"2009","unstructured":"Dohan Ehrenfest DM, de Peppo GM, Doglioli P, Sammartino G. Slow release of growth factors and thrombospondin-1 in Choukroun's platelet-rich fibrin (PRF): a gold standard to achieve for all surgical platelet concentrates technologies. 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Oral Surg Oral Med Oral Pathol Oral Radiol Endod. 2011;111:e6\u2013e11."},{"issue":"suppl","key":"i1548-1336-41-5-586-b44","series-title":"Int J Oral Maxillofac Implants","first-page":"S49","article-title":"Which hard tissue augmentation techniques are the most successful in furnishing bony support for implant placement?","volume":"22","author":"Aghaloo\n TL,","year":"2007","unstructured":"Aghaloo\n TL, \n \n Moy\n PK.\n \n \n Which hard tissue augmentation techniques are the most successful in furnishing bony support for implant placement?\n Int J Oral Maxillofac Implants. 2007;22 (suppl):S49\u2013S70. 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