{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,6,6]],"date-time":"2026-06-06T07:00:22Z","timestamp":1780729222664,"version":"3.54.1"},"reference-count":39,"publisher":"American Academy of Implant Dentistry","issue":"2","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2018,4]]},"abstract":"<jats:p>Our purpose was to evaluate the occurrence of complications and the degree of bone loss in a cohort of patients treated with fixed prostheses supported by immediately loaded dental implants. The primary aim was to compare partial versus full-arch fixed dental prostheses. We then tested the effect of sinus lifting. In the present retrospective cohort study, the patients had their implants restored with fixed dental prostheses supported by dental implants positioned in the posterior maxilla and mandible. When necessary, the maxillary sinuses were grafted with particulate autogenous bone. Patients were then ranked according to the following predictors: length of prosthesis, crown-to-implant ratio, number of crowns to number of implants ratio, and presence of sinus lifting. Outcomes were evaluated for up to 2 years regarding the peri-implant marginal bone loss and implant\/prosthesis survival rates. Fifty-eight subjects (209 implants) were rehabilitated with 25 fixed full-arch prostheses and 33 partial fixed dental implant bridges (16 supported by implants placed in grafted sinus). The mean marginal bone loss for implants supporting partial fixed dental prostheses amounted to 0.81 mm, whereas that for implants within the group of full-arch fixed dental prostheses was 1.21 mm; the comparison of the levels in the 2 groups showed a significant difference (<jats:italic>P<\/jats:italic> = .0055). A statistically significant difference (<jats:italic>P<\/jats:italic> = .0006) was found between the bone loss around maxillary implants (1.53 mm) and the bone loss around mandibular implants (1.10 mm). Two implants and 4 prostheses failed; 2-year survival rates of partial and of full-arch fixed dental prostheses, respectively, were 94.1% and 96%. Bone loss in full-arch prostheses appeared to be higher than in that of partial prosthesis. Implant-supported prostheses in the maxillae exhibited a bone loss higher than that registered in mandibles.<\/jats:p>","DOI":"10.1563\/aaid-joi-d-17-00152","type":"journal-article","created":{"date-parts":[[2017,11,28]],"date-time":"2017-11-28T12:04:44Z","timestamp":1511870684000},"page":"87-93","source":"Crossref","is-referenced-by-count":10,"title":["The Influence of Prosthesis Design on the Outcomes of Tooth Implants Immediately Placed and Loaded by Means of One-Piece Titanium Machined Restoration"],"prefix":"10.1563","volume":"44","author":[{"given":"Paolo","family":"Toti","sequence":"first","affiliation":[{"name":"Department of Surgical, Medical, Molecular and Critical Area Pathology, University of Pisa, Pisa, Italy."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Simone","family":"Marconcini","sequence":"additional","affiliation":[{"name":"Department of Surgical, Medical, Molecular and Critical Area Pathology, University of Pisa, Pisa, Italy."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Giammarinaro","family":"Enrica","sequence":"additional","affiliation":[{"name":"Department of Surgical, Medical, Molecular and Critical Area Pathology, University of Pisa, Pisa, Italy."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Giorgio","family":"Pedretti","sequence":"additional","affiliation":[{"name":"AMT MEDICAL SRL Headquarters, Gordona, Italy."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Antonio","family":"Barone","sequence":"additional","affiliation":[{"name":"Unit of Oral Surgery and Implantology, Department of Surgery, University-Hospital of Geneva, University of Geneva, Geneva, Switzerland."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ugo","family":"Covani","sequence":"additional","affiliation":[{"name":"Department of Surgical, Medical, Molecular and Critical Area Pathology, University of Pisa, Pisa, Italy."},{"name":"Tuscan Dental Institute, Fortis Dental Center, Forte dei Marmi, Italy."}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"434","reference":[{"key":"i1548-1336-44-2-87-b01","series-title":"J Periodontol","first-page":"322","article-title":"The causes of early implant bone loss: myth or science?","volume":"73","author":"Oh \n              TJ,","year":"2002","unstructured":"Oh \n              TJ, \n            \n            \n              Yoon \n              J, \n            \n            \n              Misch \n              CE, \n            \n            \n              Wang \n              HL. \n            \n          \n          The causes of early implant bone loss: myth or science?\n          J Periodontol. 2002;73:322\u2013333."},{"key":"i1548-1336-44-2-87-b02","series-title":"J Periodontol","first-page":"1998","article-title":"Gene clustering analysis in human osseous remodeling","volume":"12","author":"Sbordone \n              L,","year":"2009","unstructured":"Sbordone \n              L, \n            \n            \n              Sbordone \n              C, \n            \n            \n              Filice \n              N, \n            \n            \n              Menchini-Fabris \n              G, \n            \n            \n              Baldoni \n              M, \n            \n            \n              Toti \n              P. \n            \n          \n          Gene clustering analysis in human osseous remodeling. 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J Periodontal Res. 1997;32:166\u2013171."},{"key":"i1548-1336-44-2-87-b08","series-title":"Clin Oral Investig","first-page":"769","article-title":"Implant angulation: 2-year retrospective analysis on the influence of dental implant angle insertion on marginal bone resorption in maxillary and mandibular osseous onlay grafts","volume":"19","author":"Ramaglia \n              L,","year":"2015","unstructured":"Ramaglia \n              L, \n            \n            \n              Toti \n              P, \n            \n            \n              Sbordone \n              C, \n            \n            \n              Guidetti \n              F, \n            \n            \n              Martuscelli \n              R, \n            \n            \n              Sbordone \n              L. \n            \n          \n          Implant angulation: 2-year retrospective analysis on the influence of dental implant angle insertion on marginal bone resorption in maxillary and mandibular osseous onlay grafts. Clin Oral Investig. 2015;19:769\u2013779."},{"key":"i1548-1336-44-2-87-b09","series-title":"J Craniomaxillofac Surg","first-page":"421","article-title":"Healing of donor defect after mandibular parasymphyseal block harvesting: a 6-year computerized tomographic follow-up","volume":"40","author":"Sbordone \n              C,","year":"2012","unstructured":"Sbordone \n              C, \n            \n            \n              Toti \n              P, \n            \n            \n              Guidetti \n              F, \n            \n            \n              Martuscelli \n              R, \n            \n            \n              Califano \n              L, \n            \n            \n              Sbordone \n              L. \n            \n          \n          Healing of donor defect after mandibular parasymphyseal block harvesting: a 6-year computerized tomographic follow-up. 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Clin Oral Implants Res. 1990;1:33\u201340."},{"key":"i1548-1336-44-2-87-b14","series-title":"Cochrane Database Syst Rev","article-title":"Interventions for replacing missing teeth: different times for loading dental implants","volume":"21","author":"Esposito \n              M,","year":"2009","unstructured":"Esposito \n              M, \n            \n            \n              Grusovin \n              MG, \n            \n            \n              Achille \n              H, \n            \n            \n              Coulthard \n              P, \n            \n            \n              Worthington \n              HV. \n            \n          \n          Interventions for replacing missing teeth: different times for loading dental implants. Cochrane Database Syst Rev. 2009;21:CD003878."},{"key":"i1548-1336-44-2-87-b15","series-title":"Clin Implant Dent Relat Res","first-page":"806","article-title":"A randomized controlled clinical trial of edentulous patients treated with immediately loaded implant-supported mandibular fixed prostheses","volume":"16","author":"Alfadda \n              SA.","year":"2014","unstructured":"Alfadda \n              SA. \n            \n          \n          A randomized controlled clinical trial of edentulous patients treated with immediately loaded implant-supported mandibular fixed prostheses. Clin Implant Dent Relat Res. 2014:16:806\u2013816."},{"key":"i1548-1336-44-2-87-b16","series-title":"Int J Prosthodont","first-page":"207","article-title":"Immediate versus delayed loading of dental implants in edentulous patients' maxillae: a 6-year prospective study","volume":"27","author":"Tealdo \n              T,","year":"2014","unstructured":"Tealdo \n              T, \n            \n            \n              Menini \n              M, \n            \n            \n              Bevilacqua \n              M, \n            \n            et al. \n          Immediate versus delayed loading of dental implants in edentulous patients' maxillae: a 6-year prospective study. Int J Prosthodont. 2014;27:207\u2013214."},{"key":"i1548-1336-44-2-87-b17","series-title":"Clin Implant Dent Relat Res","first-page":"926","article-title":"Immediate versus conventional loading of post-extraction implants in the edentulous jaws","volume":"16","author":"Testori \n              T,","year":"2014","unstructured":"Testori \n              T, \n            \n            \n              Zuffetti \n              F, \n            \n            \n              Capelli \n              M, \n            \n            \n              Galli \n              F, \n            \n            \n              Weinstein \n              RL, \n            \n            \n              Del Fabbro \n              M. \n            \n          \n          Immediate versus conventional loading of post-extraction implants in the edentulous jaws. 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Clin Oral Implants Res. 2008;19:983\u2013990."},{"key":"i1548-1336-44-2-87-b23","series-title":"Int J Oral Maxillofac Implants","first-page":"668","article-title":"Implants and sinus-inlay graft in a 1-stage procedure in severely atrophied maxillae: prosthodontic aspects in a 3-year follow-up study","volume":"16","author":"Smedberg \n              JI,","year":"2001","unstructured":"Smedberg \n              JI, \n            \n            \n              Johansson \n              P, \n            \n            \n              Ekenb\u00e4ck \n              D, \n            \n            \n              Wannfors \n              D. \n            \n          \n          Implants and sinus-inlay graft in a 1-stage procedure in severely atrophied maxillae: prosthodontic aspects in a 3-year follow-up study. Int J Oral Maxillofac Implants. 2001;16:668\u2013674."},{"key":"i1548-1336-44-2-87-b24","series-title":"J Prosthet Dent","first-page":"567","article-title":"Criteria for success of osseointegrated endosseous implants","volume":"62","author":"Smith \n              DE,","year":"1989","unstructured":"Smith \n              DE, \n            \n            \n              Zarb \n              GA. \n            \n          \n          Criteria for success of osseointegrated endosseous implants. 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Int J Oral Maxillofac Implants. 2006;21:914\u2013918."},{"key":"i1548-1336-44-2-87-b26","series-title":"Clin Oral Implants Res","first-page":"546","article-title":"Immediate non-occlusal vs. early loading of dental implants in partially edentulous patients: a multicentre randomized clinical trial. Peri-implant bone and soft tissue levels","volume":"19","author":"Galli \n              F,","year":"2008","unstructured":"Galli \n              F, \n            \n            \n              Capelli \n              M, \n            \n            \n              Zuffetti \n              F, \n            \n            \n              Esposito \n              M, \n            \n            \n              Testori \n              T. \n            \n          \n          Immediate non-occlusal vs. early loading of dental implants in partially edentulous patients: a multicentre randomized clinical trial. Peri-implant bone and soft tissue levels. Clin Oral Implants Res. 2008;19:546\u2013552."},{"key":"i1548-1336-44-2-87-b27","series-title":"Int J Oral Maxillofac Implants","first-page":"329","article-title":"The efficacy of full-arch immediately restored implant-supported reconstructions in extraction and healed sites: a 36-month retrospective evaluation","volume":"25","author":"Artzi \n              Z,","year":"2010","unstructured":"Artzi \n              Z, \n            \n            \n              Kohen \n              J, \n            \n            \n              Carmeli \n              G, \n            \n            \n              Karmon \n              B, \n            \n            \n              Lor \n              A, \n            \n            \n              Ormianer \n              Z. \n            \n          \n          The efficacy of full-arch immediately restored implant-supported reconstructions in extraction and healed sites: a 36-month retrospective evaluation. Int J Oral Maxillofac Implants. 2010;25:329\u2013335."},{"key":"i1548-1336-44-2-87-b28","series-title":"Int J Oral Maxillofac Implants","first-page":"1116","article-title":"Immediate versus conventional loading for the maxilla with implants placed into fresh and healed extraction sites to support a full-arch fixed prosthesis: nonrandomized controlled clinical study","volume":"28","author":"Penarrocha-Oltra \n              D,","year":"2013","unstructured":"Penarrocha-Oltra \n              D, \n            \n            \n              Covani \n              U, \n            \n            \n              Aparicio \n              A, \n            \n            \n              Ata-Ali \n              J, \n            \n            \n              Penarrocha-Diago \n              M, \n            \n            \n              Penarrocha-Diago \n              M. \n            \n          \n          Immediate versus conventional loading for the maxilla with implants placed into fresh and healed extraction sites to support a full-arch fixed prosthesis: nonrandomized controlled clinical study. 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Clin Oral Implants Res. 2010;21:459\u2013465."},{"key":"i1548-1336-44-2-87-b31","series-title":"Int J Oral Maxillofac Implants","first-page":"428","article-title":"A clinical study of edentulous patients rehabilitated according to the \u201call on four\u201d immediate function protocol","volume":"27","author":"Crespi \n              R,","year":"2012","unstructured":"Crespi \n              R, \n            \n            \n              Vinci \n              R, \n            \n            \n              Cappar\u00e9 \n              P, \n            \n            \n              Romanos \n              GE, \n            \n            \n              Gherlone \n              E. \n            \n          \n          A clinical study of edentulous patients rehabilitated according to the \u201call on four\u201d immediate function protocol. Int J Oral Maxillofac Implants. 2012;27:428\u2013434."},{"key":"i1548-1336-44-2-87-b32","series-title":"Int J Oral Maxillofac Implants","first-page":"1177","article-title":"de Ara\u00fajo Nobre M, Lopes A. Immediate rehabilitation of completely edentulous arches with a four-implant prosthesis concept in difficult conditions: an open cohort study with a mean follow-up of 2 years","volume":"27","author":"Malo \n              P,","year":"2012","unstructured":"Malo \n              P, \n            \n          \n          de Ara\u00fajo Nobre M, Lopes A. Immediate rehabilitation of completely edentulous arches with a four-implant prosthesis concept in difficult conditions: an open cohort study with a mean follow-up of 2 years. Int J Oral Maxillofac Implants. 2012;27:1177\u20131190."},{"key":"i1548-1336-44-2-87-b33","series-title":"Clin Implant Dent Relat Res","first-page":"102","article-title":"Retrospective study of short and extra-short implants placed in posterior regions: influence of crown-to-implant ratio on marginal bone loss","volume":"17","author":"Anitua \n              E,","year":"2015","unstructured":"Anitua \n              E, \n            \n            \n              Pi\u00f1as \n              L, \n            \n            \n              Orive \n              G. \n            \n          \n          Retrospective study of short and extra-short implants placed in posterior regions: influence of crown-to-implant ratio on marginal bone loss. Clin Implant Dent Relat Res. 2015;17:102\u2013110."},{"key":"i1548-1336-44-2-87-b34","series-title":"Clin Oral Implants Res","first-page":"240","article-title":"Influence of crown-implant ratio on implant success rates and crestal bone levels: a 36-month follow-up prospective study","volume":"25","author":"Malchiodi \n              L,","year":"2014","unstructured":"Malchiodi \n              L, \n            \n            \n              Cucchi \n              A, \n            \n            \n              Ghensi \n              P, \n            \n            \n              Consonni \n              D, \n            \n            \n              Nocini \n              PF. \n            \n          \n          Influence of crown-implant ratio on implant success rates and crestal bone levels: a 36-month follow-up prospective study. 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Clin Oral Implants Res. 2004;15:625\u2013642."},{"issue":"Suppl 4","key":"i1548-1336-44-2-87-b37","series-title":"Clin Oral Implants Res","first-page":"59","article-title":"Survival and complication rates of implant-supported fixed partial dentures with cantilevers: a systematic review","volume":"20","author":"Zurdo \n              J,","year":"2009","unstructured":"Zurdo \n              J, \n            \n            \n              Romao \n              C, \n            \n            \n              Wennstrom \n              JL. \n            \n          \n          Survival and complication rates of implant-supported fixed partial dentures with cantilevers: a systematic review. 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Clin Implant Dent Relat Res. 2012;14:88\u201399."},{"key":"i1548-1336-44-2-87-b39","series-title":"Clin Implant Dent Relat Res","first-page":"434","article-title":"Immediate rehabilitation of the extremely atrophic mandible with fixed full-prosthesis supported by four implants","volume":"14","author":"Weinstein \n              R,","year":"2012","unstructured":"Weinstein \n              R, \n            \n            \n              Agliardi \n              E, \n            \n            \n              Fabbro \n              MD, \n            \n            \n              Romeo \n              D, \n            \n            \n              Francetti \n              L. \n            \n          \n          Immediate rehabilitation of the extremely atrophic mandible with fixed full-prosthesis supported by four implants. 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