{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,7,11]],"date-time":"2025-07-11T00:40:11Z","timestamp":1752194411356,"version":"3.41.2"},"reference-count":24,"publisher":"American Academy of Implant Dentistry","issue":"3","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2022,6]]},"abstract":"<jats:p>\n          <jats:italic>Actinomyces<\/jats:italic> species are members of normal oral flora that may give rise to a rare disease\u2014oral actinomycosis. Presented herein is a case of early implant failure associated with actinomycosis in an otherwise healthy 43-year-old female and the treatment adopted after explantation. Clinically, 1 month after the implant placement, the peri-implant soft tissues were hyperplastic and associated with an excessive tissue reaction, bleeding, suppuration, deep probing depth, and implant mobility of #19 and #20 implants. Both implants were removed and all granulomatous tissues were thoroughly debrided. Histopathological examination revealed signs of acute ulcerative inflammatory reaction and <jats:italic>Actinomyces<\/jats:italic> colonies. The patient was prescribed short-term oral penicillins. Six months after explantation, the deficient bone was augmented using a combination of absorbable collagen membrane, autogenous block bone, and xenograft. The patient was followed for 1 year; and subsequently, 2 implants were re-inserted at the same positions. The patient was followed and no recurrences were observed. Implant failure due to actinomycosis is an extremely rare condition, and a definitive diagnosis is therefore essential for successful treatment.<\/jats:p>","DOI":"10.1563\/aaid-joi-d-20-00301","type":"journal-article","created":{"date-parts":[[2021,6,6]],"date-time":"2021-06-06T13:10:24Z","timestamp":1622985024000},"page":"226-236","source":"Crossref","is-referenced-by-count":1,"title":["An Unusual Case of Early Dental Implant Failure in an Otherwise-Healthy Patient due to Actinomycosis"],"prefix":"10.1563","volume":"48","author":[{"given":"Hanife Merva","family":"Parlak","sequence":"first","affiliation":[{"name":"Hacettepe University Faculty of Dentistry, Periodontology Department, Ankara, Turkey."}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Abdullah C.","family":"Akman","sequence":"additional","affiliation":[{"name":"Hacettepe University Faculty of Dentistry, Periodontology Department, Ankara, Turkey."}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Elnur","family":"Comerdov","sequence":"additional","affiliation":[{"name":"Hacettepe University Faculty of Dentistry, Periodontology Department, Ankara, Turkey."}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Kemal","family":"Kosemehmetoglu","sequence":"additional","affiliation":[{"name":"Hacettepe University Faculty of Medicine, Department of Pathology, Ankara, Turkey."}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ahmet Cagkan","family":"Inkaya","sequence":"additional","affiliation":[{"name":"Hacettepe University Faculty of Medicine, Department of Infectious Diseases and Clinical Microbiology, Ankara, Turkey."}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"H. Gencay","family":"Keceli","sequence":"additional","affiliation":[{"name":"Hacettepe University Faculty of Dentistry, Periodontology Department, Ankara, Turkey."}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"434","reference":[{"key":"i1548-1336-48-3-226-b01","series-title":"Infect Di\u015f Clin Microbiol","first-page":"158","article-title":"Splenic actinomycosis in a patient with chronic granulomatous disease: a case report and review of the literature","volume":"1","author":"Ayaz","year":"2019","unstructured":"Ayaz\n              CM,\n            \n            \n              Hasanl\u0131\n              N,\n            \n            \n              Demirci-Duarte\n              S,\n            \n            et al.\n          \n          Splenic actinomycosis in a patient with chronic granulomatous disease: a case report and review of the literature.\n\t\t\t\t\tInfect Di\u015f Clin 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disease","volume":"10","author":"Boyanova","year":"2015","unstructured":"Boyanova\n              L,\n            \n            \n              Kolarov\n              R,\n            \n            \n              Mateva\n              L,\n            \n            \n              Markovska\n              R,\n            \n            \n              Mitov\n              I.\n            \n          \n          Actinomycosis: a frequently forgotten disease.\n\t\t\t\t\tFuture Microbiol.\n\t\t\t\t\t2015;10:613\u2013628."},{"key":"i1548-1336-48-3-226-b04","series-title":"J Oral Implantol","first-page":"206","article-title":"Implant failure associated with actinomycosis in a medically compromised patient","volume":"39","author":"Sun","year":"2013","unstructured":"Sun\n              CX,\n            \n            \n              Henkin\n              JM,\n            \n            \n              Ririe\n              C,\n            \n            \n              Javadi\n              E.\n      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lesions","volume":"8","author":"Acar","year":"2017","unstructured":"Acar\n              B,\n            \n            \n              \u00c7a\u011flayan\n              F,\n            \n            \n              \u0130nkaya\n              A\u00c7,\n            \n            \n              Kurtulan\n              O.\n            \n          \n          Actinomyces-associated lesions located in the gingiva: case report of rare gingival lesions.\n\t\t\t\t\tContemp Clin Dent.\n\t\t\t\t\t2017;8:182\u2013184."}],"container-title":["Journal of Oral 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