{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,2,1]],"date-time":"2026-02-01T19:34:39Z","timestamp":1769974479961,"version":"3.49.0"},"reference-count":31,"publisher":"American Academy of Implant Dentistry","issue":"5","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2024,10]]},"abstract":"<jats:p>Guided bone regeneration involving the use of titanium mesh and platelet-rich fibrin could be a feasible approach in cases of severely atrophic ridges. The purpose of this case report was to present an esthetic and functional rehabilitation in the anterior maxilla with the installation of dental implants in conjunction with guided bone regeneration using titanium mesh and advanced platelet-rich fibrin (A-PRF). A 60-year-old patient presented bone atrophy and partial edentulism in the anterior maxilla. After clinical and cone beam computed tomography assessment, guided bone regeneration was planned using a titanium mesh and A-PRF with xenograft bone. After 8 months of healing, the dental implants were placed with the aid of a surgical guide to obtain accurate 3-dimensional positioning. Prosthetic rehabilitation was carried out with individualized crowns. After 2 years of follow-up, radiographic analysis demonstrated a good quality and density of the bone tissue adjacent to the dental implants. No radiolucent areas were observed, and there were no clinical signs of failure. In cases of severe atrophy, using a titanium mesh and A-PRF proved to be a feasible alternative for bone reconstruction prior to dental implant placement. This approach can aid dental professionals in achieving an ideal implant positioning for rehabilitation with individualized crowns.<\/jats:p>","DOI":"10.1563\/aaid-joi-d-23-00154","type":"journal-article","created":{"date-parts":[[2024,8,19]],"date-time":"2024-08-19T11:31:10Z","timestamp":1724067070000},"page":"514-518","source":"Crossref","is-referenced-by-count":1,"title":["Bone Regeneration in the Anterior Maxilla With Titanium Mesh and Advanced-Platelet-Rich Fibrin: A Case Report With 2-Year Follow-up"],"prefix":"10.1563","volume":"50","author":[{"given":"Carlos Roberto Garcia","family":"Ara\u00fajo","sequence":"first","affiliation":[{"name":"Department of Implant Dentistry, Faculdade S\u00e3o Leopoldo Mandic, Instituto S\u00e3o Leopoldo Mandic, Campinas, Brazil"},{"name":"IMPLA, Belo Horizonte, Brazil"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Roberto Carlos de","family":"Ara\u00fajo","sequence":"additional","affiliation":[{"name":"IMPLA, Belo Horizonte, Brazil"},{"name":"Department of Dental Prosthesis, Faculdade S\u00e3o Leopoldo Mandic, Instituto S\u00e3o Leopoldo Mandic, Campinas, Brazil"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Cristiano Garcia","family":"Ara\u00fajo","sequence":"additional","affiliation":[{"name":"IMPLA, Belo Horizonte, Brazil"},{"name":"Department of Dental Prosthesis, Faculdade S\u00e3o Leopoldo Mandic, Instituto S\u00e3o Leopoldo Mandic, Campinas, Brazil"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ana Paula","family":"Carvalho","sequence":"additional","affiliation":[{"name":"Department of Dental Clinics, Oral Pathology, and Oral Surgery, School of Dentistry, Federal University of Minas, Brazil"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Lu\u00eds Ot\u00e1vio Miranda","family":"Cota","sequence":"additional","affiliation":[{"name":"Department of Dental Clinics, Oral Pathology, and Oral Surgery, School of Dentistry, Federal University of Minas, Brazil"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Paulo Ant\u00f4nio","family":"Martins-J\u00fanior","sequence":"additional","affiliation":[{"name":"Department of Child and Adolescent Oral Health, School of Dentistry, Federal University of Minas Gerais, Brazil"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Andr\u00e9 Antonio","family":"Pelegrine","sequence":"additional","affiliation":[{"name":"Department of Implant Dentistry, Faculdade S\u00e3o Leopoldo Mandic, Instituto S\u00e3o Leopoldo Mandic, Campinas, Brazil"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"434","reference":[{"key":"i1548-1336-50-5-514-b01","series-title":"Clin Implant Dent Relat Res","first-page":"123","article-title":"Stability and crestal bone behavior following simultaneous placement of multiple dental implants (two or more) with the bone splitting technique: a clinical and radiographic evaluation","volume":"19","author":"Gehrke","year":"2017","unstructured":"Gehrke\n              SA,\n            \n            \n              Mat\u00e9 S\u00e1nchez de Val\n              JE,\n            \n            \n              Ram\u00edrez Fern\u00e1ndez\n              MP,\n            \n            \n              Shibli\n              JA,\n            \n            \n              Rossetti\n              PH,\n            \n            \n              Calvo Guirado\n              JL.\n            \n          \n          Stability and crestal bone behavior following simultaneous placement of multiple dental implants (two or more) with the bone splitting technique: a clinical and radiographic evaluation. 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Oral Maxillofac Surg Clin North Am. 2019;31:331\u2013338."},{"key":"i1548-1336-50-5-514-b03","series-title":"Materials (Basel)","first-page":"1120","article-title":"Innovative concepts and recent breakthrough for engineered graft and constructs for bone regeneration: a literature systematic review","volume":"15","author":"Inchinglo","year":"2022","unstructured":"Inchinglo\n              F,\n            \n            \n              Hazballa\n              D,\n            \n            \n              Inchingolo\n              AD,\n            \n            et al.\n          \n          Innovative concepts and recent breakthrough for engineered graft and constructs for bone regeneration: a literature systematic review. 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Gen Dent. 2020;68:56\u201360."},{"key":"i1548-1336-50-5-514-b10","series-title":"JOI","first-page":"43","article-title":"Implant site preparation application of injectable platelet-rich fibrin for vertical and horizontal bone regeneration: a clinical report","volume":"48","author":"Thanasrisuebwong","year":"2022","unstructured":"Thanasrisuebwong\n              P,\n            \n            \n              Kiattavorncharoen\n              S,\n            \n            \n              Deeb\n              GR,\n            \n            \n              Bencharit\n              S.\n            \n          \n          Implant site preparation application of injectable platelet-rich fibrin for vertical and horizontal bone regeneration: a clinical report. 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Oral Surg Oral Med Oral Pathol Oral Radiol Endod. 2006;101:e37\u2013e44."},{"key":"i1548-1336-50-5-514-b13","series-title":"Periodontol 2000","first-page":"213","article-title":"Horizontal bone-augmentation procedures in implant dentistry: prosthetically guided regeneration","volume":"77","author":"Chiapasco","year":"2018","unstructured":"Chiapasco\n              M,\n            \n            \n              Casentini\n              P.\n            \n          \n          Horizontal bone-augmentation procedures in implant dentistry: prosthetically guided regeneration. 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J Int Oral Health. 2023;14:543\u2013550."},{"key":"i1548-1336-50-5-514-b16","series-title":"Clin Oral Investig","first-page":"553","article-title":"Clinical results of implant placement in resorbed ridges using simultaneous guided bone regeneration: a multicenter case series","volume":"19","author":"Konstantinidis","year":"2015","unstructured":"Konstantinidis\n              I,\n            \n            \n              Kumar\n              T,\n            \n            \n              Kher\n              U,\n            \n            \n              Stanitsas\n              PD,\n            \n            \n              Hinrichs\n              JE,\n            \n            \n              Kotsakis\n              GA.\n            \n          \n          Clinical results of implant placement in resorbed ridges using simultaneous guided bone regeneration: a multicenter case series. 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Biomed Res Int. 2016;2016:8901253."},{"key":"i1548-1336-50-5-514-b31","series-title":"Ann Maxillofac Surg","first-page":"28","article-title":"Wound healing and bone regeneration in postextraction sockets with and without platelet-rich fibrin","volume":"8","author":"Srinivas","year":"2018","unstructured":"Srinivas\n              B,\n            \n            \n              Das\n              P,\n            \n            \n              Rana\n              MM,\n            \n            \n              Qureshi\n              AQ,\n            \n            \n              Vaidya\n              KC,\n            \n            \n              Ahmed Raziuddin\n              SJ.\n            \n          \n          Wound healing and bone regeneration in postextraction sockets with and without platelet-rich fibrin. 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