{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,9,21]],"date-time":"2025-09-21T17:26:54Z","timestamp":1758475614464,"version":"3.41.2"},"reference-count":55,"publisher":"American Academy of Implant Dentistry","issue":"4","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2015,8]]},"abstract":"Narrow diameter implants may be at increased risk of overload due to occlusal forces; therefore, implants with higher fatigue strength may be beneficial. The aim of this observational study was to evaluate survival and success of narrow diameter (\u00d8 3.3 mm) TiZr alloy (Roxolid, Institut Straumann AG, Basel, Switzerland) implants for 2 years in daily dental practice. This was a prospective, non-interventional, multicenter study; no specific patient inclusion or exclusion criteria were applied. Each patient received at least one TiZr implant; the treatment plan, including implant loading and final restoration, was at the investigator's discretion. The primary outcome was implant survival and success after 1 year. Secondary outcomes included 2-year survival and success and marginal bone level change. A total of 603 implants were placed in 357 patients. Cumulative survival and success rates were 97.8% and 97.6%, respectively, after 1 year and 97.6% and 97.4%, respectively, after 2 years. Bone levels remained stable in the majority of patients, and soft tissue remained stable up to 2 years. Within the limitations of a non-interventional study design, TiZr implants showed excellent survival and success with minimal bone loss up to 2 years in daily dental practice. The results compare favorably with those of small-diameter implants in controlled clinical trials.<\/jats:p>","DOI":"10.1563\/aaid-joi-d-13-00149","type":"journal-article","created":{"date-parts":[[2014,3,25]],"date-time":"2014-03-25T18:24:25Z","timestamp":1395771865000},"page":"e118-e125","source":"Crossref","is-referenced-by-count":30,"title":["A Prospective Noninterventional Study to Evaluate Survival and Success of Reduced Diameter Implants Made From Titanium-Zirconium Alloy"],"prefix":"10.1563","volume":"41","author":[{"given":"Bilal","family":"Al-Nawas","sequence":"first","affiliation":[{"name":"Oral and Maxillofacial Surgery, University Medical Center of the Johannes Gutenberg-University Mainz, Germany."}]},{"given":"Peter","family":"Domagala","sequence":"additional","affiliation":[{"name":"Institute of Dental Implants and Periodontics, Gurnee, Ill."}]},{"given":"Giuliano","family":"Fragola","sequence":"additional","affiliation":[{"name":"Private practice, Puerto de Los Leones, Madrid, Spain."}]},{"given":"Philip","family":"Freiberger","sequence":"additional","affiliation":[{"name":"Freiberger Dental Practice, London, UK."}]},{"given":"Alberto","family":"Ortiz-Vig\u00f3n","sequence":"additional","affiliation":[{"name":"Cl\u00ednica Ortiz-Vig\u00f3n S.L., Vizcaya, Spain."}]},{"given":"Paul","family":"Rousseau","sequence":"additional","affiliation":[{"name":"Private practice, Paris, France."}]},{"given":"Jo\u00e3o","family":"Tondela","sequence":"additional","affiliation":[{"name":"Faculty of Medicine of University of Coimbra (FMUC), Coimbra, Portugal."}]}],"member":"434","reference":[{"key":"i1548-1336-41-4-e118-b01","series-title":"Clin Oral Implants Res","first-page":"39","article-title":"A systematic review on survival and success rates of implants placed immediately into fresh extraction sockets after at least 1 year","volume":"23","author":"Lang\n NP,","year":"2012","unstructured":"Lang\n NP, \n \n Pun\n L, \n \n Lau\n KY, \n \n Li\n KY, \n \n Wong\n MC.\n \n \n A systematic review on survival and success rates of implants placed immediately into fresh extraction sockets after at least 1 year. Clin Oral Implants Res. 2012;23:39\u201366."},{"key":"i1548-1336-41-4-e118-b02","series-title":"J Clin Periodontol","first-page":"216","article-title":"A systematic review of the success of sinus floor elevation and survival of implants inserted in combination with sinus floor elevation","volume":"35","author":"Pjetursson\n BE,","year":"2008","unstructured":"Pjetursson\n BE, \n \n Tan\n WC, \n \n Zwahlen\n M, \n \n Lang\n NP.\n \n \n A systematic review of the success of sinus floor elevation and survival of implants inserted in combination with sinus floor elevation. J Clin Periodontol. 2008;35:216\u2013240."},{"key":"i1548-1336-41-4-e118-b03","series-title":"Implant Den.t","first-page":"5","article-title":"Implant success, survival and failure: the International Congress of Oral Implantologists (ICOI) Pisa Consensus Conference","volume":"17","author":"Misch\n CE,","year":"2008","unstructured":"Misch\n CE, \n \n Perel\n ML, \n \n Wang\n HL, \n et al\n . Implant success, survival and failure: the International Congress of Oral Implantologists (ICOI) Pisa Consensus Conference. Implant Den.t2008;17:5\u201315."},{"key":"i1548-1336-41-4-e118-b04","series-title":"Int J Prosthodont","first-page":"109","article-title":"Survival rates of teeth, implants, and double crown-retained removable prostheses: a systematic literature review","volume":"24","author":"Koller\n B,","year":"2011","unstructured":"Koller\n B, \n \n Att\n W, \n \n Strub\n JR.\n \n \n Survival rates of teeth, implants, and double crown-retained removable prostheses: a systematic literature review. Int J Prosthodont. 2011;24:109\u2013117."},{"key":"i1548-1336-41-4-e118-b05","series-title":"Clin Oral Implants Res","first-page":"1117","article-title":"Morse taper connection implants supporting \u201cplanned\u201d maxillary and mandibular bar-retained overdentures: a 5-year prospective multicenter study","volume":"22","author":"Mangano\n C,","year":"2011","unstructured":"Mangano\n C, \n \n Mangano\n F, \n \n Shibli\n JA, \n \n Ricci\n M, \n \n Sammons\n RL, \n \n Figliuzzi\n M.\n \n \n Morse taper connection implants supporting \u201cplanned\u201d maxillary and mandibular bar-retained overdentures: a 5-year prospective multicenter study. Clin Oral Implants Res. 2011;22:1117\u20131124."},{"key":"i1548-1336-41-4-e118-b06","series-title":"Int Dent J","first-page":"363","article-title":"Assessing the evidence supporting the claims of select dental implant surfaces: a systematic review","volume":"58","author":"Bhatavadekar\n N.","year":"2008","unstructured":"Bhatavadekar\n N.\n \n \n Assessing the evidence supporting the claims of select dental implant surfaces: a systematic review. Int Dent J. 2008;58:363\u2013370."},{"key":"i1548-1336-41-4-e118-b07","series-title":"Int Dent J","first-page":"359","article-title":"Helping the clinician make evidence-based implant selections. A systematic review and qualitative analysis of dental implant studies over a 20 year period","volume":"60","author":"Bhatavadekar\n N.","year":"2010","unstructured":"Bhatavadekar\n N.\n \n \n Helping the clinician make evidence-based implant selections. A systematic review and qualitative analysis of dental implant studies over a 20 year period. Int Dent J. 2010;60:359\u2013369."},{"key":"i1548-1336-41-4-e118-b08","series-title":"J Prosthet Dent","first-page":"108","article-title":"Structural aspects of the interface between tissue and titanium implants","volume":"50","author":"Hansson\n HA,","year":"1983","unstructured":"Hansson\n HA, \n \n Albrektsson\n T, \n \n Branemark\n PI.\n \n \n Structural aspects of the interface between tissue and titanium implants. J Prosthet Dent. 1983;50:108\u2013113."},{"issue":"suppl 5","key":"i1548-1336-41-4-e118-b09","series-title":"J R Soc Interface","first-page":"S515","article-title":"Titanium oral implants: surface characteristics, interface biology and clinical outcome","volume":"7","author":"Palmquist\n A,","year":"2010","unstructured":"Palmquist\n A, \n \n Omar\n OM, \n \n Esposito\n M, \n \n Lausmaa\n J, \n \n Thomsen\n P.\n \n \n Titanium oral implants: surface characteristics, interface biology and clinical outcome. J R Soc Interface. 2010;7(suppl 5):S515\u2013S527."},{"key":"i1548-1336-41-4-e118-b10","series-title":"Int J Oral Maxillofac Implants","first-page":"63","article-title":"On implant surfaces: a review of current knowledge and opinions","volume":"25","author":"Wennerberg\n A,","year":"2010","unstructured":"Wennerberg\n A, \n \n Albrektsson\n T.\n \n \n On implant surfaces: a review of current knowledge and opinions. Int J Oral Maxillofac Implants. 2010;25:63\u201374."},{"key":"i1548-1336-41-4-e118-b11","series-title":"J Biomed Mater Res B Appl Biomater","first-page":"544","article-title":"Potential of chemically modified hydrophilic surface characteristics to support tissue integration of titanium dental implants","volume":"88","author":"Schwarz\n F,","year":"2009","unstructured":"Schwarz\n F, \n \n Wieland\n M, \n \n Schwartz\n Z\n \n et al\n . Potential of chemically modified hydrophilic surface characteristics to support tissue integration of titanium dental implants. 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Dent Mater J. 2007;26:260\u2013267."},{"key":"i1548-1336-41-4-e118-b15","series-title":"Expert Rev Med Devices","first-page":"241","article-title":"Improving osseointegration of dental implants","volume":"7","author":"Elias\n CN,","year":"2010","unstructured":"Elias\n CN, \n \n Meirelles\n L.\n \n \n Improving osseointegration of dental implants. Expert Rev Med Devices. 2010;7:241\u2013256."},{"key":"i1548-1336-41-4-e118-b16","series-title":"Clin Oral Implants Res","first-page":"873","article-title":"A pilot study to evaluate the success and survival rate of titanium-zirconium implants in partially edentulous patients: results after 24 months of follow-up","volume":"23","author":"Barter\n S,","year":"2012","unstructured":"Barter\n S, \n \n Stone\n P, \n \n Br\u00e4gger\n U.\n \n \n A pilot study to evaluate the success and survival rate of titanium-zirconium implants in partially edentulous patients: results after 24 months of follow-up. Clin Oral Implants Res. 2012;23:873\u2013881."},{"key":"i1548-1336-41-4-e118-b17","series-title":"Clin Oral Implants Res","first-page":"349","article-title":"Early osseointegration to hydrophilic and hydrophobic implant surfaces in humans","volume":"22","author":"Lang\n NP,","year":"2011","unstructured":"Lang\n NP, \n \n Salvi\n GE, \n \n Huynh-Ba\n G, \n \n Ivanovski\n S, \n \n Donos\n N, \n \n Bosshardt\n DD.\n \n \n Early osseointegration to hydrophilic and hydrophobic implant surfaces in humans. Clin Oral Implants Res. 2011;22:349\u2013356."},{"key":"i1548-1336-41-4-e118-b18","series-title":"J Dent Res","first-page":"529","article-title":"Enhanced bone apposition to a chemically modified SLA titanium surface","volume":"83","author":"Buser\n D,","year":"2004","unstructured":"Buser\n D, \n \n Broggini\n N, \n \n Wieland\n M, \n et al\n . Enhanced bone apposition to a chemically modified SLA titanium surface. J Dent Res. 2004;83:529\u2013533."},{"key":"i1548-1336-41-4-e118-b19","series-title":"Eur Cell Mater","first-page":"273","article-title":"Bone apposition to a titanium-zirconium alloy implant, as compared to two other titanium-containing implants","volume":"23","author":"Saulacic\n N,","year":"2012","unstructured":"Saulacic\n N, \n \n Bosshardt\n DD, \n \n Bornstein\n MM, \n \n Berner\n S, \n \n Buser\n D.\n \n \n Bone apposition to a titanium-zirconium alloy implant, as compared to two other titanium-containing implants. Eur Cell Mater. 2012;23:273\u2013286."},{"key":"i1548-1336-41-4-e118-b20","series-title":"J Periodontol","first-page":"1453","article-title":"Tissue integration of a new titanium-zirconium dental implant: a comparative histologic and radiographic study in the canine","volume":"82","author":"Thoma\n DS,","year":"2011","unstructured":"Thoma\n DS, \n \n Jones\n AA, \n \n Dard\n M, \n \n Grize\n L, \n \n Obrecht\n M, \n \n Cochran\n DL.\n \n \n Tissue integration of a new titanium-zirconium dental implant: a comparative histologic and radiographic study in the canine. J Periodontol. 2011;82:1453\u20131461."},{"key":"i1548-1336-41-4-e118-b21","series-title":"Materials","first-page":"1348","article-title":"A review of titanium zirconium (TiZr) alloys for use in endosseous dental implants","volume":"5","author":"Grandin\n HM,","year":"2012","unstructured":"Grandin\n HM, \n \n Berner\n S, \n \n Dard\n M.\n \n \n A review of titanium zirconium (TiZr) alloys for use in endosseous dental implants. Materials. 2012;5:1348\u20131360."},{"key":"i1548-1336-41-4-e118-b22","series-title":"Clin Oral Implants Res","first-page":"515","article-title":"How successful are small-diameter implants? A literature review","volume":"23","author":"Sohrabi\n K,","year":"2012","unstructured":"Sohrabi\n K, \n \n Mushantat\n A, \n \n Esfandiari\n S, \n \n Feine\n J.\n \n \n How successful are small-diameter implants? A literature review. Clin Oral Implants Res. 2012;23:515\u2013525."},{"issue":"suppl","key":"i1548-1336-41-4-e118-b23","series-title":"Int J Oral Maxillofac Implants","first-page":"43","article-title":"Systematic review on success of narrow diameter dental implants","volume":"29","author":"Klein\n MO,","year":"2014","unstructured":"Klein\n MO, \n \n Schiegnitz\n E, \n \n Al-Nawas\n B.\n \n \n Systematic review on success of narrow diameter dental implants. Int J Oral Maxillofac Implants. 2014;29(suppl):43\u201354."},{"key":"i1548-1336-41-4-e118-b24","series-title":"Clin Oral Implants Res","first-page":"553","article-title":"The impact of loads on standard diameter, small diameter and mini implants: a comparative laboratory study","volume":"19","author":"Allum\n SR,","year":"2008","unstructured":"Allum\n SR, \n \n Tomlinson\n RA, \n \n Joshi\n R.\n \n \n The impact of loads on standard diameter, small diameter and mini implants: a comparative laboratory study. Clin Oral Implants Res. 2008;19:553\u2013559."},{"key":"i1548-1336-41-4-e118-b25","series-title":"Int J Oral Maxillofac Implants","first-page":"929","article-title":"Load fatigue performance of a single-tooth implant abutment system: effect of diameter","volume":"21","author":"Quek\n CE,","year":"2006","unstructured":"Quek\n CE, \n \n Tan\n KB, \n \n Nicholls\n JI.\n \n \n Load fatigue performance of a single-tooth implant abutment system: effect of diameter. Int J Oral Maxillofac Implants. 2006;21:929\u2013936."},{"key":"i1548-1336-41-4-e118-b26","series-title":"Clin Implant Dent Relat Res","first-page":"896","article-title":"A double-blind randomized controlled trial (RCT) of titanium-13zirconium versus titanium grade IV small-diameter bone level implants in edentulous mandibles \u2013 results from a 1-year observation period","volume":"14","author":"Al-Nawas\n B,","year":"2012","unstructured":"Al-Nawas\n B, \n \n Br\u00e4gger\n U, \n \n Meijer\n HJ, \n et al\n . A double-blind randomized controlled trial (RCT) of titanium-13zirconium versus titanium grade IV small-diameter bone level implants in edentulous mandibles \u2013 results from a 1-year observation period. Clin Implant Dent Relat Res. 2012;14:896\u2013904."},{"key":"i1548-1336-41-4-e118-b27","series-title":"Clin Oral Implants Res","first-page":"33","article-title":"Tissue integration of non-submerged implants. 1-year results of a prospective study with 100 ITI hollow-cylinder and hollow-screw implants","volume":"1","author":"Buser\n D,","year":"1990","unstructured":"Buser\n D, \n \n Weber\n HP, \n \n Lang\n NP.\n \n \n Tissue integration of non-submerged implants. 1-year results of a prospective study with 100 ITI hollow-cylinder and hollow-screw implants. Clin Oral Implants Res. 1990;1:33\u201340."},{"key":"i1548-1336-41-4-e118-b28","series-title":"Clin Oral Implants Res","first-page":"351","article-title":"Implant-supported fixed prostheses in the edentulous maxilla. A 2-year clinical and radiographic follow-up of treatment with non-submerged ITI implants","volume":"15","author":"Bergkvist\n G,","year":"2004","unstructured":"Bergkvist\n G, \n \n Sahlholm\n S, \n \n Nilner\n K, \n \n Lindh\n C.\n \n \n Implant-supported fixed prostheses in the edentulous maxilla. A 2-year clinical and radiographic follow-up of treatment with non-submerged ITI implants. Clin Oral Implants Res. 2004;15:351\u2013359."},{"key":"i1548-1336-41-4-e118-b29","series-title":"Clin Oral Implants Res","first-page":"94","article-title":"Prosthetic treatment of maxillary lateral incisor agenesis with osseointegrated implants: a 24-39-month prospective clinical study","volume":"17","author":"Zarone\n F,","year":"2006","unstructured":"Zarone\n F, \n \n Sorrentino\n R, \n \n Vaccaro\n F, \n \n Russo\n S.\n \n \n Prosthetic treatment of maxillary lateral incisor agenesis with osseointegrated implants: a 24-39-month prospective clinical study. Clin Oral Implants Res. 2006;17:94\u2013101."},{"key":"i1548-1336-41-4-e118-b30","series-title":"Eur J Dent Educ","first-page":"4","article-title":"Periodontal health in Europe: future trends based on treatment needs and the provision of periodontal services \u2013 position paper 1","volume":"14","author":"K\u00f6nig\n J,","year":"2010","unstructured":"K\u00f6nig\n J, \n \n Holtfreter\n B, \n \n Kocher\n T.\n \n \n Periodontal health in Europe: future trends based on treatment needs and the provision of periodontal services \u2013 position paper 1. Eur J Dent Educ. 2010;14:4\u201324."},{"key":"i1548-1336-41-4-e118-b31","series-title":"J Periodontol","first-page":"1406","article-title":"Research, Science and Therapy Committee of the American Academy of Periodontology. Position paper: epidemiology of periodontal diseases","volume":"76","author":"Burt\n B;","year":"2005","unstructured":"Burt\n B; \n \n Research, Science and Therapy Committee of the American Academy of Periodontology. Position paper: epidemiology of periodontal diseases. J Periodontol. 2005;76:1406\u20131419."},{"key":"i1548-1336-41-4-e118-b32","series-title":"J Clin Periodontol","first-page":"338","article-title":"Has the prevalence of periodontitis changed during the last 30 years?","volume":"35","author":"Hugoson\n A,","year":"2008","unstructured":"Hugoson\n A, \n \n Nordeyrd\n O.\n \n \n Has the prevalence of periodontitis changed during the last 30 years?\n J Clin Periodontol. 2008;35:338\u2013345."},{"key":"i1548-1336-41-4-e118-b33","series-title":"J Clin Periodontol","first-page":"9","article-title":"Periodontitis as a potential risk factor for peri-implantitis","volume":"36","author":"Renvert\n S,","year":"2009","unstructured":"Renvert\n S, \n \n Persson\n GR.\n \n \n Periodontitis as a potential risk factor for peri-implantitis. J Clin Periodontol. 2009;36:9\u201314."},{"key":"i1548-1336-41-4-e118-b34","series-title":"Int J Oral Maxillofac Implants","first-page":"39","article-title":"History of treated periodontitis and smoking as risks for implant therapy","volume":"24","author":"Heitz-Mayfield\n LJ,","year":"2009","unstructured":"Heitz-Mayfield\n LJ, \n \n Huynh-Ba\n G.\n \n \n History of treated periodontitis and smoking as risks for implant therapy. Int J Oral Maxillofac Implants. 2009;24:39\u201368."},{"key":"i1548-1336-41-4-e118-b35","series-title":"J Clin Periodontol","first-page":"173","article-title":"Peri-implant disease in subjects with and without preventive maintenance: a 5-year follow-up","volume":"39","author":"Costa\n FO,","year":"2012","unstructured":"Costa\n FO, \n \n Takenaka-Martinez\n S, \n \n Cota\n LO, \n \n Ferreira\n SD, \n \n Silva\n GL, \n \n Coste\n JE.\n \n \n Peri-implant disease in subjects with and without preventive maintenance: a 5-year follow-up. J Clin Periodontol. 2012;39:173\u2013181."},{"key":"i1548-1336-41-4-e118-b36","series-title":"Eur J Oral Implantol","first-page":"307","article-title":"Outcome of dental implants in patients with and without a history of periodontitis: a 5-year pragmatic multicenter retrospective cohort study of 1727 patients","volume":"3","author":"Gianserra\n R,","year":"2010","unstructured":"Gianserra\n R, \n \n Cavalcanti\n R, \n \n Oreglia\n F, \n \n Manfredonia\n MF, \n \n Esposito\n M.\n \n \n Outcome of dental implants in patients with and without a history of periodontitis: a 5-year pragmatic multicenter retrospective cohort study of 1727 patients. Eur J Oral Implantol. 2010;3:307\u2013314."},{"issue":"4","key":"i1548-1336-41-4-e118-b37","series-title":"Cochrane Database Syst Rev","article-title":"Interventions for replacing missing teeth: horizontal and vertical bone augmentation techniques for dental implant treatment","author":"Esposito\n M,","year":"2009","unstructured":"Esposito\n M, \n \n Grusovin\n MG, \n \n Felice\n P, \n \n Karatzopoulos\n G, \n \n Worthington\n HV, \n \n Coulthard\n P.\n \n \n Interventions for replacing missing teeth: horizontal and vertical bone augmentation techniques for dental implant treatment. Cochrane Database Syst Rev. 2009;4:CD003607."},{"key":"i1548-1336-41-4-e118-b38","series-title":"Clin Implant Dent Relat Res","first-page":"517","article-title":"Four modalities of single implant treatment in the anterior maxilla: a clinical, radiographic, and aesthetic evaluation","volume":"15","author":"Cosyn\n J,","year":"2013","unstructured":"Cosyn\n J, \n \n Eghbali\n A, \n \n Hanselaer\n L, \n et al\n . Four modalities of single implant treatment in the anterior maxilla: a clinical, radiographic, and aesthetic evaluation. 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Int J Oral Maxillofac Surg. 2012;41:847\u2013852."},{"key":"i1548-1336-41-4-e118-b40","series-title":"Med Biol Eng Comput","first-page":"681","article-title":"Influence of graft quality and marginal bone loss on implants placed in the maxillary grafted sinus: a finite element study","volume":"48","author":"Inglam\n S,","year":"2010","unstructured":"Inglam\n S, \n \n Suebnukarn\n S, \n \n Tharanon\n W, \n \n Apatananon\n T, \n \n Sitthiseripratip\n K.\n \n \n Influence of graft quality and marginal bone loss on implants placed in the maxillary grafted sinus: a finite element study. Med Biol Eng Comput. 2010;48:681\u2013689."},{"key":"i1548-1336-41-4-e118-b41","series-title":"Clin Implant Dent Relat Res","first-page":"9","article-title":"Cutting torque measurements in conjunction with implant placement in grafted and nongrafted maxillas as an objective evaluation of bone density: a possible method for identifying early implant failures?","volume":"6","author":"Johansson\n B,","year":"2004","unstructured":"Johansson\n B, \n \n B\u00e4ck\n T, \n \n Hirsch\n JM.\n \n \n Cutting torque measurements in conjunction with implant placement in grafted and nongrafted maxillas as an objective evaluation of bone density: a possible method for identifying early implant failures?\n Clin Implant Dent Relat Res. 2004;6:9\u201315."},{"key":"i1548-1336-41-4-e118-b42","series-title":"Clin Implant Dent Relat Res","first-page":"279","article-title":"Effect of diameter and length on stress distribution of the alveolar crest around immediate loading implants","volume":"11","author":"Ding\n X,","year":"2009","unstructured":"Ding\n X, \n \n Liao\n SH, \n \n Zhi\n XH, \n \n Zhang\n XH, \n \n Zhang\n L.\n \n \n Effect of diameter and length on stress distribution of the alveolar crest around immediate loading implants. Clin Implant Dent Relat Res. 2009;11:279\u2013287."},{"key":"i1548-1336-41-4-e118-b43","series-title":"Biomed Tech (Berl)","first-page":"21","article-title":"Biomechanical finite element analysis of small diameter and short dental implants: extensive study of commercial implants","volume":"57","author":"Bourauel\n C,","year":"2012","unstructured":"Bourauel\n C, \n \n Aitlahrach\n M, \n \n Heinemann\n F, \n \n Hasan\n I.\n \n \n Biomechanical finite element analysis of small diameter and short dental implants: extensive study of commercial implants. Biomed Tech (Berl). 2012;57:21\u201332."},{"key":"i1548-1336-41-4-e118-b44","series-title":"Mater Trans","first-page":"2260","article-title":"Improved biocompatibility of titanium-zirconium alloy (Ti-Zr): tissue reaction and sensitization to Ti-Zr alloy compared with pure Ti and Zr in rat implantation study","volume":"46","author":"Ikarashi\n Y,","year":"2005","unstructured":"Ikarashi\n Y, \n \n Toyoda\n K, \n \n Kobayashi\n E, \n et al\n . Improved biocompatibility of titanium-zirconium alloy (Ti-Zr): tissue reaction and sensitization to Ti-Zr alloy compared with pure Ti and Zr in rat implantation study. Mater Trans. 2005;46:2260\u20132267."},{"key":"i1548-1336-41-4-e118-b45","series-title":"J Biomed Mater Res","first-page":"943","article-title":"Mechanical properties of the binary titanium-zirconium alloys and their potential for biomedical materials","volume":"29","author":"Kobayashi\n E,","year":"1995","unstructured":"Kobayashi\n E, \n \n Matsumoto\n S, \n \n Doi\n H, \n \n Yoneyama\n T, \n \n Hamanaka\n H.\n \n \n Mechanical properties of the binary titanium-zirconium alloys and their potential for biomedical materials. J Biomed Mater Res. 1995;29:943\u2013950."},{"key":"i1548-1336-41-4-e118-b46","series-title":"Int J Oral Maxillofac Implants","first-page":"662","article-title":"Analysis of incidence and associated factors with fractured implants: a retrospective study","volume":"15","author":"Eckert\n SE,","year":"2000","unstructured":"Eckert\n SE, \n \n Meraw\n SJ, \n \n Cal\n E, \n \n Ow\n RK.\n \n \n Analysis of incidence and associated factors with fractured implants: a retrospective study. Int J Oral Maxillofac Implants. 2000;15:662\u2013667."},{"key":"i1548-1336-41-4-e118-b47","series-title":"Dent Mater J","first-page":"633","article-title":"Nonlinear stress analysis of titanium implants by finite element method","volume":"27","author":"Nagasawa\n S,","year":"2008","unstructured":"Nagasawa\n S, \n \n Hayano\n K, \n \n Niino\n T, \n et al\n . Nonlinear stress analysis of titanium implants by finite element method. Dent Mater J. 2008;27:633\u2013639."},{"key":"i1548-1336-41-4-e118-b48","series-title":"J Prosthodont","first-page":"286","article-title":"Bivariate evaluation of cylinder implant diameter and length: a three-dimensional finite element analysis","volume":"17","author":"Kong\n L,","year":"2008","unstructured":"Kong\n L, \n \n Sun\n Y, \n \n Hu\n K, \n et al\n . Bivariate evaluation of cylinder implant diameter and length: a three-dimensional finite element analysis. J Prosthodont. 2008;17:286\u2013293."},{"key":"i1548-1336-41-4-e118-b49","series-title":"Clin Implant Dent Relat Res","first-page":"538","article-title":"Evaluation of a new titanium-zirconium dental implant: a biomechanical and histological comparative study in the mini pig","volume":"14","author":"Gottlow\n J,","year":"2012","unstructured":"Gottlow\n J, \n \n Dard\n M, \n \n Kjellson\n F, \n \n Obrecht\n M, \n \n Sennerby\n L.\n \n \n Evaluation of a new titanium-zirconium dental implant: a biomechanical and histological comparative study in the mini pig. Clin Implant Dent Relat Res. 2012;14:538\u2013545."},{"key":"i1548-1336-41-4-e118-b50","series-title":"Acta Radiol","first-page":"179","article-title":"Safety and diagnostic image quality of iopromide: results of a large non-interventional observational study of European and Asian patients (IMAGE)","volume":"53","author":"Palkowitsch\n P,","year":"2012","unstructured":"Palkowitsch\n P, \n \n Lengsfeld\n P, \n \n Stauch\n K, \n et al\n . Safety and diagnostic image quality of iopromide: results of a large non-interventional observational study of European and Asian patients (IMAGE). Acta Radiol. 2012;53:179\u2013186."},{"key":"i1548-1336-41-4-e118-b51","series-title":"Int J Clin Pract","first-page":"675","article-title":"First interim analysis of the GIDEON (Global Investigation of therapeutic Decisions about hepatocellular carcinoma and Of its treatment with sorafeNib) non-interventional study","volume":"66","author":"Lencioni\n R,","year":"2012","unstructured":"Lencioni\n R, \n \n Kudo\n M, \n \n Ye\n SL, \n et al\n . First interim analysis of the GIDEON (Global Investigation of therapeutic Decisions about hepatocellular carcinoma and Of its treatment with sorafeNib) non-interventional study. Int J Clin Pract. 2012;66:675\u2013683."},{"key":"i1548-1336-41-4-e118-b52","series-title":"Clin Drug Invest","first-page":"99","article-title":"SUPRA Study Group. Monthly administration of a continuous erythropoietin receptor activator provides efficient haemoglobin control in non-dialysis patients during routine clinical practice: results from the non-interventional, single-cohort, multicenter, SUPRA study","volume":"32","author":"Heidenreich\n S,","year":"2012","unstructured":"Heidenreich\n S, \n \n Leistikow\n F, \n \n Zinn\n S, \n et al;\n \n SUPRA Study Group. Monthly administration of a continuous erythropoietin receptor activator provides efficient haemoglobin control in non-dialysis patients during routine clinical practice: results from the non-interventional, single-cohort, multicenter, SUPRA study. Clin Drug Invest. 2012;32:99\u2013110."},{"key":"i1548-1336-41-4-e118-b53","series-title":"Wien Klin Wochenschr","first-page":"25","article-title":"Use of OROS hydromorphone in the treatment of osteoarthritis and osteoporosis: a pooled analysis of three non-interventional studies focusing on different starting doses","volume":"124","author":"Ringe\n SD,","year":"2012","unstructured":"Ringe\n SD, \n \n Sch\u00e4fer\n S, \n \n Wimmer\n AM, \n \n Giesecke\n T.\n \n \n Use of OROS hydromorphone in the treatment of osteoarthritis and osteoporosis: a pooled analysis of three non-interventional studies focusing on different starting doses. Wien Klin Wochenschr. 2012;124:25\u201331."},{"key":"i1548-1336-41-4-e118-b54","series-title":"BMC Public Health","first-page":"249","article-title":"A systematic review of retention methods in population-based cohort studies","volume":"11","author":"Booker\n CL,","year":"2011","unstructured":"Booker\n CL, \n \n Harding\n S, \n \n Benzeval\n M.\n \n \n A systematic review of retention methods in population-based cohort studies. BMC Public Health. 2011;11:249."},{"key":"i1548-1336-41-4-e118-b55","series-title":"BMJ","first-page":"969","article-title":"Reporting attrition in randomised controlled trials","volume":"232","author":"Dumville\n JC,","year":"2006","unstructured":"Dumville\n JC, \n \n Torgerson\n DJ, \n \n Hewitt\n CE.\n \n \n Reporting attrition in randomised controlled trials. 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