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Die Gefl\u00fcgelpest-Verordnung unterscheidet zwischen hochpathogenem Influenza-A-Virus der Subtypen H5 und H7, wenn multiple basische Aminos\u00e4uren im Spaltbereich des H\u00e4magglutininmolek\u00fcls durch Virus-, Antigen- oder Genomnachweis vorliegen, und niedrigpathogenen avi\u00e4ren Influenzaviren der Subtypen H5 und H7, wenn entweder der intraven\u00f6se Pathogenit\u00e4tsindex kleiner als 1,2 ist oder keine basischen Aminos\u00e4uren im Spaltbereich des H\u00e4magglutininmolek\u00fcls vorliegen. Zur klassischen Gefl\u00fcgelpest werden Aspekte der Diagnose, Bek\u00e4mpfung einschlie\u00dflich T\u00f6tung, Therapie und Impfung beschrieben. Derzeitige Optionen und die engen Grenzen einer oralen Therapie der Gefl\u00fcgelpest mit Neuraminidase-Hemmern (z. B. Oseltamivir) werden dargestellt. Auf genehmigten Antrag d\u00fcrfen einzeln gekennzeichnete Zoo- und Zierv\u00f6gel mit zugelassenen Inaktivatimpfstoffen immunisiert werden. Vektorvakzinen kamen in Deutschland bisher nicht zum Einsatz. Influenza-A-Viren mit anderen H\u00e4magglutininen (H1\u2013H4, H6, H8\u2013H18) k\u00f6nnen ebenfalls Infektionen und schwere Krankheitsverl\u00e4ufe hervorrufen. Diese unterliegen keiner gesetzlichen Reglementierung und durch zeitgerechte Impfung mit Inaktivatvakzinen lassen sich Erkrankungen verhindern.<\/jats:p>","DOI":"10.15653\/tpg-140681","type":"journal-article","created":{"date-parts":[[2014,11,17]],"date-time":"2014-11-17T13:57:40Z","timestamp":1416232660000},"page":"375-385","source":"Crossref","is-referenced-by-count":0,"title":["Die klassische Gefl\u00fcgelpest und die Influenza-A-Viren des Hausgefl\u00fcgels und der V\u00f6gel"],"prefix":"10.15653","volume":"42","author":[{"given":"E. 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