{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,6,25]],"date-time":"2025-06-25T16:10:07Z","timestamp":1750867807152,"version":"3.41.0"},"reference-count":35,"publisher":"Georg Thieme Verlag KG","issue":"06","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Tierarztl Prax Ausg G"],"published-print":{"date-parts":[[2017]]},"abstract":"<jats:title>Zusammenfassung<\/jats:title><jats:p>Gegenstand und Ziel: Die interstitielle Nephritis als eine Form renaler Erkrankungen tritt bei Schweinen h\u00e4ufig auf. Die nur wenigen Forschungsarbeiten auf diesem Gebiet machen eine weitere Erforschung von Pr\u00e4valenz und \u00c4tiologie dieser Erkrankung notwendig. Material und Methoden: Insgesamt 169 Nieren konventionell und \u00f6kologisch gehaltenener Schweine wurden am Schlachthof zuf\u00e4llig ausgew\u00e4hlt und bez\u00fcglich des Entz\u00fcndungsgrades und des Auftretens von Entz\u00fcndungszellen untersucht. Des Weiteren wurden die Proben mittels Immunhistologie und In-situ-Hybridisierung auf porzines Circovirus Typ 2 (PCV2) als infekti\u00f6ses Agens untersucht. Ergebnisse: Alle untersuchten Nieren wiesen eine geringgradige Form der interstitiellen Nephritis auf und als Entz\u00fcndungszellen fanden sich Lymphozyten, Makrophagen, Plasmazellen, eosinophile und neutrophile Granulozyten in unterschiedlichen H\u00e4ufigkeiten. Hinsichtlich Entz\u00fcndungsgrad und Auftreten von Entz\u00fcndungszellen ergaben sich in Nieren von Schweinen der beiden Haltungsformen signifikante (p \u2264 0,0001) Unterschiede. \u00d6kologisch gehaltene Schweine zeigten im Vergleich zu konventionell gehaltenen Tieren signifikant (p \u2264 0,0001) h\u00e4ufiger eine geringgradige Form der Nephritis sowie ein signifikant (p \u2264 0,0001) h\u00e4ufigeres Vorkommen von Lymphozyten und Makrophagen. Bei Schweinen aus konventioneller Haltung bestand im Vergleich signifikant (p \u2264 0,0001) h\u00e4ufiger eine geringgradige bis mittelgradige Nephritis und es lagen signifikant (p \u2264 0,0001) h\u00e4ufiger Lymphozyten, Plasmazellen, Makrophagen sowie neutrophile Granulozyten vor. Nur in der Niere eines Tieres lie\u00df sich DNS von PCV2 nachweisen. Schlussfolgerung: Die interstitielle Nephritis trat bei \u00f6kologisch und konventionellen Schweinen auf. PCV2 konnte als bedeutendes Pathogen f\u00fcr die interstitielle Nephritis bei Schlachtschweinen ausgeschlossen werden. Klinische Relevanz: Aufgrund der hohen Pr\u00e4valenz der interstitiellen Nephritis und der unbekannten Ursache sind weitere Untersuchungen sinnvoll, um klinische Relevanz und Pathogenese weiter einzugrenzen.<\/jats:p>","DOI":"10.15653\/tpg-170079","type":"journal-article","created":{"date-parts":[[2017,9,5]],"date-time":"2017-09-05T10:38:13Z","timestamp":1504607893000},"page":"350-356","source":"Crossref","is-referenced-by-count":1,"title":["Vorkommen der interstitiellen Nephritis bei Schweinen"],"prefix":"10.15653","volume":"45","author":[{"given":"Mechthild","family":"Freitag","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Wolfgang","family":"Baumg\u00e4rtner","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ines","family":"Spiekermeier","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"194","published-online":{"date-parts":[[2018,1,9]]},"reference":[{"key":"10.15653\/TPG-170079-1","doi-asserted-by":"publisher","DOI":"10.1177\/104063870001200102"},{"issue":"3","key":"10.15653\/TPG-170079-2","first-page":"290","volume":"3","author":"Baker","year":"1989","journal-title":"Can J Vet Res"},{"issue":"2","key":"10.15653\/TPG-170079-3","first-page":"109","volume":"35","author":"B\u00fcngener","year":"1984","journal-title":"Tropenmed Parasitol"},{"key":"10.15653\/TPG-170079-4","doi-asserted-by":"publisher","DOI":"10.1016\/S0378-1135(03)00042-7"},{"key":"10.15653\/TPG-170079-5","doi-asserted-by":"publisher","DOI":"10.1128\/JCM.40.5.1848-1850.2002"},{"issue":"3","key":"10.15653\/TPG-170079-6","doi-asserted-by":"crossref","first-page":"145","DOI":"10.54846\/jshap\/461","volume":"14","author":"Carpenter","year":"2006","journal-title":"J Swine Health Prod"},{"key":"10.15653\/TPG-170079-7","doi-asserted-by":"publisher","DOI":"10.1016\/j.vetpar.2010.11.019"},{"key":"10.15653\/TPG-170079-8","doi-asserted-by":"publisher","DOI":"10.1177\/104063879700900216"},{"key":"10.15653\/TPG-170079-9","unstructured":"De Vries V. Erhebung von Organbefunden und Konfiskatabz\u00fcgen von Schlachtschweinen an Schlachth\u00f6fen in der Schweiz und deren Korrelation mit Betriebs- und Managementdaten. University of Zurich; 2010. Available from: http:\/\/www.zora.uzh.ch\/42567\/1\/Erhebung1.pdf"},{"key":"10.15653\/TPG-170079-10","doi-asserted-by":"publisher","DOI":"10.1136\/vr.150.5.139"},{"issue":"4","key":"10.15653\/TPG-170079-11","first-page":"313","volume":"32","author":"Filho","year":"2012","journal-title":"Braz J Vet Med"},{"key":"10.15653\/TPG-170079-12","doi-asserted-by":"publisher","DOI":"10.1177\/104063870902100425"},{"key":"10.15653\/TPG-170079-13","doi-asserted-by":"publisher","DOI":"10.1016\/j.vetmic.2009.02.005"},{"key":"10.15653\/TPG-170079-14","doi-asserted-by":"publisher","DOI":"10.1111\/j.1439-0442.1992.tb00221.x"},{"key":"10.15653\/TPG-170079-15","doi-asserted-by":"publisher","DOI":"10.1016\/0021-9975(77)90028-7"},{"key":"10.15653\/TPG-170079-16","doi-asserted-by":"publisher","DOI":"10.1099\/vir.0.81586-0"},{"key":"10.15653\/TPG-170079-17","first-page":"35","volume":"6","author":"Larsen","year":"1954","journal-title":"Nord Vet Med"},{"issue":"1","key":"10.15653\/TPG-170079-18","first-page":"175","volume":"34","author":"Lee","year":"2011","journal-title":"Pertanika J Trop Agric Sci"},{"key":"10.15653\/TPG-170079-19","doi-asserted-by":"publisher","DOI":"10.1124\/dmd.105.006791"},{"key":"10.15653\/TPG-170079-20","doi-asserted-by":"publisher","DOI":"10.1136\/vr.165.17.501"},{"key":"10.15653\/TPG-170079-21","doi-asserted-by":"publisher","DOI":"10.1016\/j.rvsc.2005.10.005"},{"key":"10.15653\/TPG-170079-22","doi-asserted-by":"crossref","unstructured":"Maxie MG, Newman SJ. Urinary System. In: Jubb, Kennedy and Palmer\u2019s Pathology of Domestic Animals, 5th ed. Maxie MG, ed. St. Louis: Mosby Elsevier 2007; 425-522","DOI":"10.1016\/B978-070202823-6.50114-7"},{"key":"10.15653\/TPG-170079-23","unstructured":"Newman SJ, Confer AW, Panciera RJ. Urinary System. In: Pathologic Basis of Veterinary Disease, 4th ed. McGavin MD, Zachary JF, eds. St. Louis: Mosby Elsevier 2007; 613-692"},{"key":"10.15653\/TPG-170079-24","doi-asserted-by":"publisher","DOI":"10.1177\/104063879300500223"},{"key":"10.15653\/TPG-170079-25","doi-asserted-by":"publisher","DOI":"10.1177\/0300985812450726"},{"key":"10.15653\/TPG-170079-26","doi-asserted-by":"publisher","DOI":"10.1354\/vp.08-VP-0078-R-FL"},{"key":"10.15653\/TPG-170079-27","doi-asserted-by":"publisher","DOI":"10.1053\/jcpa.1998.0258"},{"key":"10.15653\/TPG-170079-28","doi-asserted-by":"publisher","DOI":"10.1354\/vp.45-1-12"},{"key":"10.15653\/TPG-170079-29","doi-asserted-by":"publisher","DOI":"10.1177\/030098588902600510"},{"key":"10.15653\/TPG-170079-30","doi-asserted-by":"publisher","DOI":"10.1354\/vp.44-5-621"},{"key":"10.15653\/TPG-170079-31","unstructured":"Sheik-Omar AR, Kadir AR, Bahaman AR. A study on the pathology of swine kidneys condemned at slaughter at an abattoir in Malaysia. Proceedings of the 3rd AAAP Animal Sci Congress, May 6-10, 1985; Vol. 1: 516-518"},{"key":"10.15653\/TPG-170079-32","doi-asserted-by":"publisher","DOI":"10.1186\/s12917-016-0817-2"},{"key":"10.15653\/TPG-170079-33","doi-asserted-by":"publisher","DOI":"10.1177\/0192623311406930"},{"key":"10.15653\/TPG-170079-34","unstructured":"Weiss E. Harnorgane. In: Grundriss der speziellen pathologischen Anatomie der Haustiere. 6. Aufl. Dahme E, Weiss E, Hrsg. Stuttgart: Enke 2007; 173-201"},{"key":"10.15653\/TPG-170079-35","doi-asserted-by":"publisher","DOI":"10.3168\/jds.S0022-0302(04)73158-6"}],"container-title":["Tier\u00e4rztliche Praxis Ausgabe G: Gro\u00dftiere \/ Nutztiere"],"original-title":[],"language":"de","link":[{"URL":"http:\/\/www.thieme-connect.de\/products\/ejournals\/pdf\/10.15653\/TPG-170079.pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,6,25]],"date-time":"2025-06-25T15:36:14Z","timestamp":1750865774000},"score":1,"resource":{"primary":{"URL":"http:\/\/www.thieme-connect.de\/DOI\/DOI?10.15653\/TPG-170079"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2017]]},"references-count":35,"journal-issue":{"issue":"06","published-online":{"date-parts":[[2018,1,9]]},"published-print":{"date-parts":[[2017]]}},"URL":"https:\/\/doi.org\/10.15653\/tpg-170079","relation":{},"ISSN":["1434-1220","2567-5834"],"issn-type":[{"type":"print","value":"1434-1220"},{"type":"electronic","value":"2567-5834"}],"subject":[],"published":{"date-parts":[[2017]]}}}