{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,4,29]],"date-time":"2026-04-29T00:11:48Z","timestamp":1777421508913,"version":"3.51.4"},"reference-count":45,"publisher":"Georg Thieme Verlag KG","issue":"02","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Tierarztl Prax Ausg K"],"published-print":{"date-parts":[[2016]]},"abstract":"<jats:title>Zusammenfassung<\/jats:title><jats:p>Gegenstand: Berner Sennenhunde (BSH) haben h\u00e4ufiger Antik\u00f6rper gegen Borrelia burgdorferi sensu lato (Bbsl) als andere Hunderassen, aber es ist nicht bekannt, ob dies auch f\u00fcr andere Erreger gilt. Das Ziel dieser Studie war zu untersuchen, ob BSH h\u00e4ufiger und h\u00f6here Antik\u00f6rpertiter gegen Bbsl, Anaplasma phagocytophilum (Ap) und verschiedene Serovare von Leptospira (L.) interrogans zeigen. Material und Methoden: In die Studie wurden 171 BSH und 57 Kontrollhunde eingeschlossen. Als Kontrollgruppe dienten gro\u00dfe (&lt; 30 kg), langhaarige Hunde mit dunklem Fell. Alle Blutproben wurden mithilfe eines Zwei-Stufen-Tests (kinetischer computergest\u00fctzter enzymgekoppelter Immunadsorptionstest [KELA] und Western Blot) auf das Vorliegen spezifischer Antik\u00f6rper gegen Bbsl, mit einem Immunfluorenzenztest auf die Anwesenheit von spezifischen Antik\u00f6rpern gegen Ap und mit einem Mikroagglutinationstest auf das Vorliegen spezifischer Antik\u00f6rper gegen verschiedene Serovare von L. interrogans untersucht. Ergebnisse: BSH wiesen eine signifikant h\u00f6here Pr\u00e4valenz von Antik\u00f6rpern gegen Bbsl auf als die Kontrollhunde (43,3% vs. 17,5%; p &gt; 0,001). Impfantik\u00f6rper gegen Bbsl blieben bei der Pr\u00e4valenzberechnung unber\u00fccksichtigt. Bei 50,3% der BSH fanden sich Antik\u00f6rper gegen Ap, w\u00e4hrend dies nur bei 24,6% der Kontrollhunde der Fall war (p &gt; 0,001). F\u00fcr BSH ergab sich dagegen im Vergleich zu den Kontrollhunden keine h\u00f6here Pr\u00e4valenz von Antik\u00f6rpern gegen alle 18 Serovare von L. interrogans au\u00dfer gegen L. copenhageni. Schlussfolgerung und klinische Relevanz: BSH zeigten eine h\u00f6here Pr\u00e4valenz von Antik\u00f6rpern gegen Bbsl und Ap sowie h\u00f6here Antik\u00f6rpertiter gegen Bbsl und Ap. Au\u00dferdem wiesen BSH signifikant h\u00f6here Antik\u00f6rpertiter gegen L. canicola (p = 0,003), L. copenhageni (p = 0,005), L. grippothyphosa (p = 0,029) und L. vanderhoedoni (p = 0,035) auf. Die Ursache daf\u00fcr und eventuelle klinische Auswirkungen sind bisher unbekannt.<\/jats:p>","DOI":"10.15654\/tpk-140962","type":"journal-article","created":{"date-parts":[[2016,3,23]],"date-time":"2016-03-23T12:26:30Z","timestamp":1458735990000},"page":"77-85","source":"Crossref","is-referenced-by-count":10,"title":["Pr\u00e4valenz von Antik\u00f6rpern gegen Borrelia burgdorferi, Anaplasma phagocytophilum und bestimmte Leptospira-interrogans-Serovare bei Berner Sennenhunden"],"prefix":"10.15654","volume":"44","author":[{"given":"E.","family":"M\u00fcller","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"R. 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