{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,1,12]],"date-time":"2026-01-12T20:52:42Z","timestamp":1768251162177,"version":"3.49.0"},"reference-count":22,"publisher":"Georg Thieme Verlag KG","issue":"03","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Tierarztl Prax Ausg K"],"published-print":{"date-parts":[[2016]]},"abstract":"<jats:title>Zusammenfassung<\/jats:title><jats:p>Ein 8-j\u00e4hriger Australian-Shepherd-R\u00fcde wurde mit Blutung aus der Lefze und H\u00e4moabdomen vorgestellt. H\u00e4matologisch fielen eine mittelgradige Thrombopenie und An\u00e4mie auf. Mittels Sonographie des Abdomens und Laparotomie wurde keine Blutungsursache gefunden. Nach einer Plasmatransfusion stabilisierte sich der Zustand des Hundes zun\u00e4chst. Im weiteren Verlauf wurden ein hochgradiger Von-Willebrand- Faktor-Mangel und ein Faktor-VIII-Mangel diagnostiziert. Nach Auftreten erneuter Blutungen wurde mittels parasitologischer Kot - untersuchung und PCR aus EDTA-Blut eine Angiostrongylus-vasorum-Infektion nachgewiesen. Im Anschluss an eine erfolgreiche Therapie mit Fenbendazol lagen Von-Willebrand-Faktor und Faktor-VIII im Referenzbereich. Es handelt sich um den zweiten Fallbericht eines Hundes mit Angiostrongylose-assoziertem Von-Willebrand-Faktor-Mangel und um den ersten Fallbericht mit gleichzeitigem Nachweis eines Faktor- VIII-Mangels.<\/jats:p>","DOI":"10.15654\/tpk-150743","type":"journal-article","created":{"date-parts":[[2016,5,18]],"date-time":"2016-05-18T04:07:34Z","timestamp":1463544454000},"page":"189-193","source":"Crossref","is-referenced-by-count":1,"title":["Erworbener Von-Willebrand-Faktor- und Faktor-VIIIMangel durch eine Angiostrongylose bei einem Hund"],"prefix":"10.15654","volume":"44","author":[{"given":"Alexander","family":"Pack","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Sylvia","family":"Hausmann","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Reto","family":"Neiger","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Lisa","family":"Hausmann","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"194","published-online":{"date-parts":[[2017,12,18]]},"reference":[{"key":"10.15654\/TPK-150743-1","doi-asserted-by":"publisher","DOI":"10.1111\/jsap.12370"},{"key":"10.15654\/TPK-150743-2","doi-asserted-by":"publisher","DOI":"10.1007\/s00436-009-1494-x"},{"issue":"5","key":"10.15654\/TPK-150743-3","first-page":"326","volume":"41","author":"Barutzki","year":"2013","journal-title":"Tier\u00e4rztl Prax"},{"key":"10.15654\/TPK-150743-4","doi-asserted-by":"publisher","DOI":"10.1111\/j.1748-5827.2005.tb00297.x"},{"key":"10.15654\/TPK-150743-5","doi-asserted-by":"publisher","DOI":"10.1016\/S0304-4017(01)00616-1"},{"key":"10.15654\/TPK-150743-6","doi-asserted-by":"publisher","DOI":"10.1016\/S0304-4017(96)00991-0"},{"issue":"2","key":"10.15654\/TPK-150743-7","first-page":"345","volume":"84","author":"Federici","year":"2000","journal-title":"Thromb Haemost"},{"key":"10.15654\/TPK-150743-8","doi-asserted-by":"publisher","DOI":"10.1111\/j.1748-5827.1999.tb03068.x"},{"key":"10.15654\/TPK-150743-9","doi-asserted-by":"publisher","DOI":"10.1016\/j.tvjl.2007.11.014"},{"issue":"6","key":"10.15654\/TPK-150743-10","doi-asserted-by":"crossref","first-page":"401","DOI":"10.1055\/s-0038-1623728","volume":"41","author":"Kruse","year":"2013","journal-title":"Tier\u00e4rztl Prax"},{"issue":"K","key":"10.15654\/TPK-150743-11","first-page":"44","volume":"40","author":"Mischke","year":"2012","journal-title":"Tier\u00e4rztl Prax"},{"key":"10.15654\/TPK-150743-12","doi-asserted-by":"publisher","DOI":"10.1016\/j.vetpar.2010.06.037"},{"key":"10.15654\/TPK-150743-13","doi-asserted-by":"publisher","DOI":"10.1016\/j.pt.2004.11.006"},{"key":"10.15654\/TPK-150743-14","doi-asserted-by":"publisher","DOI":"10.1186\/2046-0481-63-7-434"},{"key":"10.15654\/TPK-150743-15","doi-asserted-by":"publisher","DOI":"10.5326\/0440250"},{"issue":"10","key":"10.15654\/TPK-150743-16","first-page":"448","volume":"64","author":"Rafaj","year":"2009","journal-title":"Tierarztl Umsch"},{"key":"10.15654\/TPK-150743-17","doi-asserted-by":"publisher","DOI":"10.1136\/vr.138.15.360"},{"key":"10.15654\/TPK-150743-18","doi-asserted-by":"publisher","DOI":"10.1024\/0036-7281.151.6.281"},{"key":"10.15654\/TPK-150743-19","doi-asserted-by":"publisher","DOI":"10.1159\/000214858"},{"key":"10.15654\/TPK-150743-20","doi-asserted-by":"publisher","DOI":"10.1111\/j.1748-5827.2005.tb00296.x"},{"key":"10.15654\/TPK-150743-21","doi-asserted-by":"publisher","DOI":"10.1016\/j.tvjl.2007.10.018"},{"key":"10.15654\/TPK-150743-22","doi-asserted-by":"publisher","DOI":"10.5326\/15473317-31-1-70"}],"container-title":["Tier\u00e4rztliche Praxis Ausgabe K: Kleintiere \/ Heimtiere"],"original-title":[],"language":"de","link":[{"URL":"http:\/\/www.thieme-connect.de\/products\/ejournals\/pdf\/10.15654\/TPK-150743.pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2019,9,7]],"date-time":"2019-09-07T15:56:29Z","timestamp":1567871789000},"score":1,"resource":{"primary":{"URL":"http:\/\/www.thieme-connect.de\/DOI\/DOI?10.15654\/TPK-150743"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2016]]},"references-count":22,"journal-issue":{"issue":"03","published-online":{"date-parts":[[2017,12,23]]},"published-print":{"date-parts":[[2016]]}},"URL":"https:\/\/doi.org\/10.15654\/tpk-150743","relation":{},"ISSN":["1434-1239","2567-5842"],"issn-type":[{"value":"1434-1239","type":"print"},{"value":"2567-5842","type":"electronic"}],"subject":[],"published":{"date-parts":[[2016]]}}}