{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,6,11]],"date-time":"2025-06-11T04:13:51Z","timestamp":1749615231762,"version":"3.41.0"},"reference-count":41,"publisher":"Georg Thieme Verlag KG","issue":"01","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Tierarztl Prax Ausg K"],"published-print":{"date-parts":[[2017]]},"abstract":"<jats:title>Zusammenfassung<\/jats:title><jats:p>Ziel: Vergleich von Epiduralan\u00e4sthesie und ultraschallgesteuerter Nervenblockade bez\u00fcglich analgetischer Effektivit\u00e4t, klinischer Anwendbarkeit sowie Nebenwirkungen bei orthop\u00e4dischen Eingriffen an der Hintergliedma\u00dfe des Hundes. Material und Methoden: In die prospektive, geblindete, randomisierte klinische Studie gingen 22 Hunde der ASA(American Society of Anesthesiologists)-Stufen I und II ein, bei denen ein orthop\u00e4discher Eingriff ab dem distalen Drittel des Femurs erfolgte. Den Hunden wurden randomisiert 0,5 mg\/kg Bupivacainhydrochlorid (0,5%) und 0,1 mg\/kg Morphinsulfat (1%) epidural (EPI) oder unter Ultraschallkontrolle perineural (LA) verabreicht. Intraoperativ wurden Herzfrequenz, Atemfrequenz, mittlerer arterieller Blutdruck (MAP), endexspiratorische Isoflurankonzentration und die Anzahl der zus\u00e4tzlich ben\u00f6tigten Fentanyl-Boli (5 \u00b5g\/kg i. v.) als Rescue-Analgesie protokolliert. Pr\u00e4operativ sowie postoperativ zu Stunde 2, 4, 6, 12 und 24 nach Extubation wurde der Schmerzgrad mittels der Kurzform des Glasgow Composite Measure Pain Scale (GCMPS) bestimmt. Bei einem GCMPS &gt; 6 erhielten die Hunde Methadon (0,2 mg\/kg i. v.) als Rescue-Analgesie. Zur statistischen Auswertung dienten Chi-Quadrat-Test, Fisher-Test, Wilcoxon-Test sowie ein- und zweifaktorielle ANOVA mit Signifikanz bei p &lt; 0,05. Ergebnisse: W\u00e4hrend der An\u00e4sthesie betrug der mittlere MAP in Gruppe EPI 86,6 \u00b1 8,7 mmHg und in Gruppe LA 111,2 \u00b1 11,2 mmHg. Postoperativ lag der MAP in Gruppe EPI bei 95,2 \u00b113,1 mmHg und in Gruppe LA bei 119,3 \u00b1 18,2 mmHg. Der MAP der Gruppe EPI war durchgehend signifikant niedriger als der der Gruppe LA (p = 0,0421). Weitere signifikante Unterschiede ergaben sich nicht. Urinretention oder motorische Beeintr\u00e4chtigungen wurden nicht beobachtet. Schlussfolgerung: Die ultraschallgesteuerte Nervenblockade des N. femoralis und des N. ischiadicus garantieren eine zur Epiduralan\u00e4sthesie vergleichbare perioperative Analgesie. Die Unterschiede des MAP zeigten klinisch keine Relevanz. Unter station\u00e4ren Bedingungen ergab sich kein Nachteil bez\u00fcglich der Gliedma\u00dfen- und Blasenfunktion.<\/jats:p>","DOI":"10.15654\/tpk-151087","type":"journal-article","created":{"date-parts":[[2016,9,27]],"date-time":"2016-09-27T12:59:06Z","timestamp":1474981146000},"page":"5-14","source":"Crossref","is-referenced-by-count":0,"title":["Ultraschallgesteuerte Nervenblockade des Nervus femoralis und ischiadicus im Vergleich zur Epiduralan\u00e4sthesie bei orthop\u00e4dischen Eingriffen am Hund"],"prefix":"10.15654","volume":"45","author":[{"given":"Stephan","family":"Hungerb\u00fchler","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Clarissa","family":"Weil","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Alexandra","family":"Sch\u00fctter","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Karl","family":"Rohn","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Julia","family":"T\u00fcnsmeyer","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Sabine","family":"K\u00e4stner","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Mareike","family":"Arnholz","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"194","published-online":{"date-parts":[[2018,1,8]]},"reference":[{"key":"10.15654\/TPK-151087-1","first-page":"237","volume":"37","author":"Bonath","year":"1983","journal-title":"Fortschr Vetmed"},{"issue":"3-4","key":"10.15654\/TPK-151087-2","first-page":"111","volume":"29","author":"Bonath","year":"1987","journal-title":"Z Versuchstierkd"},{"key":"10.15654\/TPK-151087-3","doi-asserted-by":"publisher","DOI":"10.1111\/j.1467-2995.2011.00595.x"},{"key":"10.15654\/TPK-151087-4","doi-asserted-by":"publisher","DOI":"10.1111\/j.1467-2995.2007.00390.x"},{"key":"10.15654\/TPK-151087-5","unstructured":"Campoy L. Fundamentals of Regional Anaesthesia Using Nerve Stimulation in the Dog. In: Recent Advances in Veterinary Anesthesia and Analgesia: Companion Animals [e-book]. Gleed RD, Ludder JW, eds. Ithaca (NY, USA): International Veterinary Information Service; Letzte Aktualisierung 16. April 2008 [zitiert am 15.12.2015]. Zugang: http:\/\/www.ivis.org\/advances\/Anesthesia_Gleed\/campoy\/chapter.asp"},{"key":"10.15654\/TPK-151087-6","doi-asserted-by":"publisher","DOI":"10.1111\/j.1467-2995.2009.00518.x"},{"key":"10.15654\/TPK-151087-7","doi-asserted-by":"publisher","DOI":"10.1111\/j.1467-2995.2011.00673.x"},{"key":"10.15654\/TPK-151087-8","doi-asserted-by":"publisher","DOI":"10.2460\/javma.241.12.1605"},{"key":"10.15654\/TPK-151087-9","doi-asserted-by":"publisher","DOI":"10.2460\/ajvr.67.2.219"},{"key":"10.15654\/TPK-151087-10","doi-asserted-by":"publisher","DOI":"10.1093\/bja\/aeh224"},{"key":"10.15654\/TPK-151087-11","doi-asserted-by":"publisher","DOI":"10.1097\/00000542-198803000-00002"},{"key":"10.15654\/TPK-151087-12","doi-asserted-by":"publisher","DOI":"10.1016\/j.tvjl.2009.08.005"},{"key":"10.15654\/TPK-151087-13","doi-asserted-by":"publisher","DOI":"10.1016\/j.tvjl.2011.06.043"},{"key":"10.15654\/TPK-151087-14","doi-asserted-by":"publisher","DOI":"10.1093\/bja\/aem373"},{"key":"10.15654\/TPK-151087-15","doi-asserted-by":"publisher","DOI":"10.5326\/15473317-35-1-13"},{"key":"10.15654\/TPK-151087-16","doi-asserted-by":"publisher","DOI":"10.1093\/bja\/63.1.87"},{"key":"10.15654\/TPK-151087-17","doi-asserted-by":"publisher","DOI":"10.1093\/bjaceaccp\/mkn007"},{"key":"10.15654\/TPK-151087-18","first-page":"211","volume":"70","author":"Haberman","year":"2006","journal-title":"Can J Vet Res"},{"key":"10.15654\/TPK-151087-19","doi-asserted-by":"publisher","DOI":"10.1111\/j.1467-2987.2007.00373.x"},{"key":"10.15654\/TPK-151087-20","doi-asserted-by":"publisher","DOI":"10.1213\/01.ANE.0000184187.02887.24"},{"key":"10.15654\/TPK-151087-21","doi-asserted-by":"publisher","DOI":"10.1097\/AAP.0b013e318270bb8a"},{"key":"10.15654\/TPK-151087-22","doi-asserted-by":"publisher","DOI":"10.1111\/j.1467-2987.2004.00149.x"},{"key":"10.15654\/TPK-151087-23","doi-asserted-by":"publisher","DOI":"10.1016\/S0195-5616(08)70010-X"},{"key":"10.15654\/TPK-151087-24","doi-asserted-by":"publisher","DOI":"10.7863\/ultra.32.5.779"},{"key":"10.15654\/TPK-151087-25","doi-asserted-by":"crossref","first-page":"80","DOI":"10.1111\/j.1467-2995.2007.00356.x","volume":"35","author":"Mahler","year":"2008","journal-title":"Vet Anaesth Analg"},{"key":"10.15654\/TPK-151087-26","doi-asserted-by":"publisher","DOI":"10.1111\/j.1467-2995.2012.00731.x"},{"key":"10.15654\/TPK-151087-27","doi-asserted-by":"publisher","DOI":"10.1111\/j.1467-2995.2006.00290.x"},{"key":"10.15654\/TPK-151087-28","doi-asserted-by":"publisher","DOI":"10.1111\/j.1467-2995.2010.00572.x"},{"key":"10.15654\/TPK-151087-29","doi-asserted-by":"publisher","DOI":"10.1111\/j.1467-2995.2012.00765.x"},{"key":"10.15654\/TPK-151087-30","doi-asserted-by":"publisher","DOI":"10.1111\/j.1740-8261.2006.00171.x"},{"key":"10.15654\/TPK-151087-31","doi-asserted-by":"publisher","DOI":"10.1213\/00000539-198307000-00004"},{"key":"10.15654\/TPK-151087-32","first-page":"97","volume":"16","author":"Reid","year":"2007","journal-title":"Animal"},{"key":"10.15654\/TPK-151087-33","doi-asserted-by":"publisher","DOI":"10.1111\/j.1467-2995.2011.00608.x"},{"key":"10.15654\/TPK-151087-34","doi-asserted-by":"publisher","DOI":"10.1111\/j.1467-2995.2004.00141.x"},{"key":"10.15654\/TPK-151087-35","doi-asserted-by":"publisher","DOI":"10.1007\/s00101-013-2150-5"},{"key":"10.15654\/TPK-151087-36","doi-asserted-by":"publisher","DOI":"10.1111\/j.1467-2995.2010.00560.x"},{"key":"10.15654\/TPK-151087-37","doi-asserted-by":"crossref","first-page":"1833","DOI":"10.2460\/ajvr.1977.38.11.1833","volume":"38","author":"Steffey","year":"1977","journal-title":"Am J Vet Res"},{"key":"10.15654\/TPK-151087-38","doi-asserted-by":"publisher","DOI":"10.1016\/S0195-5616(08)70011-1"},{"key":"10.15654\/TPK-151087-39","doi-asserted-by":"publisher","DOI":"10.2460\/javma.2002.221.666"},{"key":"10.15654\/TPK-151087-40","doi-asserted-by":"publisher","DOI":"10.3415\/VCOT-11-08-0111"},{"key":"10.15654\/TPK-151087-41","doi-asserted-by":"publisher","DOI":"10.1001\/jama.1965.03080040017003"}],"container-title":["Tier\u00e4rztliche Praxis Ausgabe K: Kleintiere \/ Heimtiere"],"original-title":[],"language":"de","link":[{"URL":"http:\/\/www.thieme-connect.de\/products\/ejournals\/pdf\/10.15654\/TPK-151087.pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,6,10]],"date-time":"2025-06-10T21:34:16Z","timestamp":1749591256000},"score":1,"resource":{"primary":{"URL":"http:\/\/www.thieme-connect.de\/DOI\/DOI?10.15654\/TPK-151087"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2017]]},"references-count":41,"journal-issue":{"issue":"01","published-online":{"date-parts":[[2018,1,8]]},"published-print":{"date-parts":[[2017]]}},"URL":"https:\/\/doi.org\/10.15654\/tpk-151087","relation":{},"ISSN":["1434-1239","2567-5842"],"issn-type":[{"type":"print","value":"1434-1239"},{"type":"electronic","value":"2567-5842"}],"subject":[],"published":{"date-parts":[[2017]]}}}