{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,4,29]],"date-time":"2026-04-29T04:55:56Z","timestamp":1777438556849,"version":"3.51.4"},"reference-count":0,"publisher":"Georg Thieme Verlag KG","issue":"05","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Tierarztl Prax Ausg K"],"published-print":{"date-parts":[[2018,10]]},"abstract":"<jats:title>Zusammenfassung<\/jats:title><jats:p>Die kanine Leishmaniose ist eine Infektionskrankheit, die zunehmend an Bedeutung gewinnt, da auch in Deutschland der Hauptvektor der Leishmaniose vorkommt und Einzelf\u00e4lle autochthoner Infektionen beschrieben sind. Der Artikel fasst aktuelle Informationen \u00fcber Therapie und Pr\u00e4vention der Leishmaniose zusammen. K\u00fcrzlich wurden bei Hunden, die unter Allopurinoltherapie ein Rezidiv der Erkrankung erlitten, Allopurinol-resistente Leishmania-infantum-St\u00e4mme gefunden. Daher werden alternative Langzeittherapien erforderlich. Auch die Ergebnisse aus Langzeitstudien zur Effizienz von Miltefosin im Vergleich zu Megluminantimonat k\u00f6nnen die Wahl des leishmaniziden Therapeutikums beeinflussen. Eine Vielzahl verschiedener Repellenzien steht zur \u00dcbertragungsprophylaxe zur Verf\u00fcgung. In Europa sind zwei Impfstoffe f\u00fcr Hunde zugelassen, um das Risiko einer aktiven Infektion und den Schweregrad der klinischen Erkrankung zu reduzieren.<\/jats:p>","DOI":"10.15654\/tpk-180089","type":"journal-article","created":{"date-parts":[[2018,12,12]],"date-time":"2018-12-12T18:31:35Z","timestamp":1544639495000},"page":"315-322","source":"Crossref","is-referenced-by-count":5,"title":["Aktuelle Kenntnisse zu Therapie und Pr\u00e4vention der kaninen Leishmaniose"],"prefix":"10.15654","volume":"46","author":[{"given":"Athanasia","family":"Mitropoulou","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Nina","family":"Thom","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Andreas","family":"Moritz","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Neoklis","family":"Apostolopoulos","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"194","published-online":{"date-parts":[[2018,12,12]]},"container-title":["Tier\u00e4rztliche Praxis Ausgabe K: Kleintiere \/ Heimtiere"],"original-title":[],"language":"de","link":[{"URL":"http:\/\/www.thieme-connect.de\/products\/ejournals\/pdf\/10.15654\/TPK-180089.pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2018,12,12]],"date-time":"2018-12-12T18:31:38Z","timestamp":1544639498000},"score":1,"resource":{"primary":{"URL":"http:\/\/www.thieme-connect.de\/DOI\/DOI?10.15654\/TPK-180089"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2018,10]]},"references-count":0,"journal-issue":{"issue":"05","published-online":{"date-parts":[[2018,12,12]]},"published-print":{"date-parts":[[2018,10]]}},"URL":"https:\/\/doi.org\/10.15654\/tpk-180089","relation":{},"ISSN":["1434-1239","2567-5842"],"issn-type":[{"value":"1434-1239","type":"print"},{"value":"2567-5842","type":"electronic"}],"subject":[],"published":{"date-parts":[[2018,10]]}}}