{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,7]],"date-time":"2026-10-07T18:43:00Z","timestamp":1791398580409,"version":"4.3.3"},"reference-count":38,"publisher":"International Society of Endovascular Specialists","issue":"3","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Journal of Endovascular Therapy"],"published-print":{"date-parts":[[2005,6]]},"DOI":"10.1583\/05-1525.1","type":"journal-article","created":{"date-parts":[[2005,6,8]],"date-time":"2005-06-08T14:16:29Z","timestamp":1118240189000},"page":"371-379","source":"Crossref","is-referenced-by-count":56,"title":["<b>Drug-Eluting Biodegradable Poly-D\/L-Lactic Acid Vascular Stents:<\/b>\n                    An Experimental Pilot Study"],"prefix":"10.1583","volume":"12","author":[{"given":"Ilkka","family":"Uurto","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Joonas","family":"Mikkonen","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jyrki","family":"Parkkinen","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Leo","family":"Keski-Nisula","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Timo","family":"Nevalainen","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Minna","family":"Kellom\u00e4ki","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Pertti","family":"T\u00f6rm\u00e4l\u00e4","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Juha-Pekka","family":"Salenius","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"527","reference":[{"key":"i1545-1550-12-3-371-b1","doi-asserted-by":"crossref","unstructured":"D. L. Fischman, M. B. Leon, and D. S. Baim .et al.A randomized comparison of coronary stent placement and balloon angioplasty in treatment of coronary artery disease., N Engl J Med, 1994 .331 :496 \u2013501 .","DOI":"10.1056\/NEJM199408253310802"},{"key":"i1545-1550-12-3-371-b2","doi-asserted-by":"crossref","unstructured":"P. W. Serruys, P. de Jaegere, and F. Kiemeneij .et al.A comparison of balloon-expandable-stent implantation with balloon angioplasty in patients with coronary artery disease. Benestent Study Group., N Engl J Med, 1994 .331 :489 \u2013495 .","DOI":"10.1056\/NEJM199408253310801"},{"key":"i1545-1550-12-3-371-b3","doi-asserted-by":"crossref","unstructured":"J. W. Moses, N. Kipshidze, and M. B. Leon .Perspective of drug-eluting stents. The next revolution., Am J Cardiovasc Drugs, 2002 .2 :163 \u2013172 .","DOI":"10.2165\/00129784-200202030-00004"},{"key":"i1545-1550-12-3-371-b4","doi-asserted-by":"crossref","unstructured":"S. H. Duda, T. C. Poerner, and B. Wiesinger .et al.Drug-eluting stents: potential applications for peripheral arterial occlusive disease., J Vasc Interv Radiol, 2003 .14 :291 \u2013301 .","DOI":"10.1097\/01.RVI.0000058423.01661.57"},{"key":"i1545-1550-12-3-371-b5","doi-asserted-by":"crossref","unstructured":"C. T. Woods, and A. R. Marks .Drug-eluting stents., Annu Rev Med, 2004 .55 :169 \u2013178 .","DOI":"10.1146\/annurev.med.55.091902.105243"},{"key":"i1545-1550-12-3-371-b6","doi-asserted-by":"crossref","unstructured":"M. N. Babapulle, L. Joseph, and P. Belisle .et al.A hierarchical Bayesian meta-analysis of randomised clinical trials of drug-eluting stents., Lancet, 2004 .364 :583 \u2013591 .","DOI":"10.1016\/S0140-6736(04)16850-5"},{"key":"i1545-1550-12-3-371-b7","doi-asserted-by":"crossref","unstructured":"W. J. Van der Giessen, A. M. Lincoff, and R. S. Schwartz .et al.Coronary heart disease\/thromboses\/myocardial-infarction: marked inflammatory sequelae to implantation of biodegradable and nonbiodegradable polymers in porcine coronary arteries., Circulation, 1996 .94 :1690 \u20131697 .","DOI":"10.1161\/01.CIR.94.7.1690"},{"key":"i1545-1550-12-3-371-b8","doi-asserted-by":"crossref","unstructured":"T. Isotalo, E. Alarakkola, and M. Talja .et al.Biocompatibility testing of a new bioabsorbable X-ray positive SR-PLA 96\/4 urethral stent., J Urol, 1999 .162 :1764 \u20131767 .","DOI":"10.1016\/S0022-5347(05)68235-3"},{"key":"i1545-1550-12-3-371-b9","doi-asserted-by":"crossref","unstructured":"H. Tamai, K. Igaki, and T. Tsuji .et al.A biodegradable poly-l-lactic acid coronary stent in the porcine coronary artery., J Intervent Cardiol, 1999 .12 :443 \u2013450 .","DOI":"10.1111\/j.1540-8183.1999.tb00673.x"},{"key":"i1545-1550-12-3-371-b10","doi-asserted-by":"crossref","unstructured":"J. P. Nuutinen, C. Clerc, and R. Reinikainen .et al.Mechanical properties and in vitro degradation of bioabsorbable self-expandable braided stents., J Biomater Sci Polym Ed, 2003 .14 :255 \u2013266 .","DOI":"10.1163\/156856203763572707"},{"key":"i1545-1550-12-3-371-b11","doi-asserted-by":"crossref","unstructured":"H. Tamai, K. Igaki, and E. Kyo .et al.Initial and 6-month results of biodegradable poly-\n                      l\n                      -lactic acid coronary stent in humans., Circulation, 2000 .102 :399 \u2013404 .","DOI":"10.1161\/01.CIR.102.4.399"},{"key":"i1545-1550-12-3-371-b12","doi-asserted-by":"crossref","unstructured":"I. Uurto, H. Juuti, and J. Parkkinen .et al.Biodegradable self-expandable poly-L\/D-lactic acid vascular stent: a pilot study in canine and porcine iliac arteries., J Endovasc Ther, 2004 .11 :712 \u2013718 .","DOI":"10.1583\/04-127MR.1"},{"key":"i1545-1550-12-3-371-b13","doi-asserted-by":"crossref","unstructured":"I. Uurto, H. Juuti, and J. Parkkinen .et al.Requirements for quantitative analysis of intimal reaction in arteries treated with intraluminal stents., J Endovasc Ther, 2003 .10 :1110 \u20131116 .","DOI":"10.1177\/152660280301000614"},{"key":"i1545-1550-12-3-371-b14","doi-asserted-by":"crossref","unstructured":"R. Kornowski, M. K. Hong, and F. O. Tio .et al.In-stent restenosis: contributions of inflammatory responses and arterial injury to neointimal hyperplasia., J Am Coll Cardiol, 1998 .31 :224 \u2013230 .","DOI":"10.1016\/S0735-1097(97)00450-6"},{"key":"i1545-1550-12-3-371-b15","doi-asserted-by":"crossref","unstructured":"R. S. Schwartz, K. C. Huber, and J. G. Murphy .et al.Restenosis and the proportional neointimal response to coronary artery injury: results in a porcine model., J Am Coll Cardiol, 1992 .19 :267 \u2013274 .","DOI":"10.1016\/0735-1097(92)90476-4"},{"key":"i1545-1550-12-3-371-b16","doi-asserted-by":"crossref","unstructured":"M. R. Bennett, In-stent restenosis: pathology and implications for the development of drug-eluting stents., Heart, 2003 .89 :218 \u2013224 .","DOI":"10.1136\/heart.89.2.218"},{"key":"i1545-1550-12-3-371-b17","doi-asserted-by":"crossref","unstructured":"T. Christen, V. Verin, and M. Bochaton-Piallat .et al.Mechanisms of neointimal formation and remodeling in the porcine coronary artery., Circulation, 2001 .103 :882 \u2013888 .","DOI":"10.1161\/01.CIR.103.6.882"},{"key":"i1545-1550-12-3-371-b18","doi-asserted-by":"crossref","unstructured":"R. S. Schwartz, E. R. Edelman, and A. Carter .et al.Drug-eluting stents in preclinical studies: recommended evaluation from a consensus group., Circulation, 2002 .106 :1867 \u20131873 .","DOI":"10.1161\/01.CIR.0000033485.20594.6F"},{"key":"i1545-1550-12-3-371-b19","doi-asserted-by":"crossref","unstructured":"R. Virmani, F. D. Kolodgie, and A. Farb .et al.Drug-eluting stents: are human and animal studies comparable? Heart, 2003 .89 :133 \u2013138 .","DOI":"10.1136\/heart.89.2.133"},{"key":"i1545-1550-12-3-371-b20","doi-asserted-by":"crossref","unstructured":"R. Hoffmann, G. S. Mintz, and J. J. Popma .et al.Chronic arterial response to stent implantation: a serial intravascular ultrasound analysis of Palmaz-Schatz stents in native coronary arteries., J Am Coll Cardiol, 1996 .28 :1134 \u20131139 .","DOI":"10.1016\/S0735-1097(96)00278-1"},{"key":"i1545-1550-12-3-371-b21","doi-asserted-by":"crossref","unstructured":"E. M. Hietala, P. Maasilta, and A. St\u00e5hls .et al.Magnetic resonance evaluation of luminal patency after polylactide stent implantation: an experimental study in a rabbit aorta model., Eur Radiol, 2003 .13 :1025 \u20131032 .","DOI":"10.1007\/s00330-002-1540-x"},{"key":"i1545-1550-12-3-371-b22","doi-asserted-by":"crossref","unstructured":"M. Unverdorben, A. Spielberger, and M. Schywalsky .et al.A polyhydroxybutyrate biodegradable stent: preliminary experience in the rabbit., Cardiovasc Intervent Radiol, 2002 .25 :127 \u2013132 .","DOI":"10.1007\/s00270-001-0118-3"},{"key":"i1545-1550-12-3-371-b23","doi-asserted-by":"crossref","unstructured":"A. M. Lincoff, J. G. Furst, and S. G. Ellis .et al.Sustained local delivery of dexamethasone by a novel intravascular eluting stent to prevent restenosis in the porcine coronary injury model., J Am Coll Cardiol, 1997 .29 :808 \u2013816 .","DOI":"10.1016\/S0735-1097(96)00584-0"},{"key":"i1545-1550-12-3-371-b24","doi-asserted-by":"crossref","unstructured":"S. H. Su, R. Y. Chao, and C. L. Landau .et al.Expandable bioresorbable endovascular stent. I. Fabrication and properties., Ann Biomed Eng, 2003 .31 :667 \u2013677 .","DOI":"10.1114\/1.1575756"},{"key":"i1545-1550-12-3-371-b25","doi-asserted-by":"crossref","unstructured":"E. M. Hietala, U. S. Salminen, and A. Stahls .et al.Biodegradation of the copylomeric polylactide stent., J Vasc Res, 2001 .38 :361 \u2013369 .","DOI":"10.1159\/000051067"},{"key":"i1545-1550-12-3-371-b26","doi-asserted-by":"crossref","unstructured":"T. Yamawaki, H. Shimokawa, and T. Kozai .et al.Intramural delivery of a specific tyrosine kinase inhibitor with biodegradable stent suppresses the restenotic changes of the coronary artery in pigs in vivo., J Am Coll Cardiol, 1998 .32 :780 \u2013786 .","DOI":"10.1016\/S0735-1097(98)00312-X"},{"key":"i1545-1550-12-3-371-b27","doi-asserted-by":"crossref","unstructured":"F. Vogt, A. Stein, and G. Rettemeirr .et al.Long-term assessment of a novel biodegradable paclitaxel-eluting coronary polylactide stent., Eur Heart J, 2004 .25 :1330 \u20131340 .","DOI":"10.1016\/j.ehj.2004.06.010"},{"key":"i1545-1550-12-3-371-b28","doi-asserted-by":"crossref","unstructured":"P. Peeters, M. Bosiers, and J. Verbist .et al.Preliminary results after application of absorbable metal stents in patients with critical limb ischemia., J Endovasc Ther, 2005 .12 :1 \u20135 .","DOI":"10.1583\/04-1349R.1"},{"key":"i1545-1550-12-3-371-b29","doi-asserted-by":"crossref","unstructured":"M. C. Morice, P. W. Serruys, and J. E. Sousa .et al.A randomized comparison of a sirolimus-eluting stent with a standard stent for coronary revascularization., N Engl J Med, 2002 .346 :1773 \u20131780 .","DOI":"10.1056\/NEJMoa012843"},{"key":"i1545-1550-12-3-371-b30","doi-asserted-by":"crossref","unstructured":"J. W. Moses, M. B. Leon, and J. J. Popma .et al.Sirolimus-eluting stents versus standard stents in patients with stenosis in a native coronary artery., N Engl J Med, 2003 .349 :1315 \u20131323 .","DOI":"10.1056\/NEJMoa035071"},{"key":"i1545-1550-12-3-371-b31","doi-asserted-by":"crossref","unstructured":"A. Halkin, and G. Stone .Polymer-based paclitaxel-eluting stents in percutaneous coronary intervention: a review of the TAXUS trials., J Interv Cardiol, 2004 .17 :271 \u2013282 .","DOI":"10.1111\/j.1540-8183.2004.04040.x"},{"key":"i1545-1550-12-3-371-b32","doi-asserted-by":"crossref","unstructured":"S. H. Duda, B. Pusich, and G. Richter .et al.Sirolimus-eluting stents for the treatment of obstructive superficial femoral artery disease. Six-months results., Circulation, 2002 .106 :1505 \u20131509 .","DOI":"10.1161\/01.CIR.0000029746.10018.36"},{"key":"i1545-1550-12-3-371-b33","doi-asserted-by":"crossref","unstructured":"P. W. Radke, C. Weber, and A. Kaiser .et al.Dexamethasone and restenosis after coronary stent implantation: new indication for an old drug? Curr Pharm Des, 2004 .10 :349 \u2013355 .","DOI":"10.2174\/1381612043453324"},{"key":"i1545-1550-12-3-371-b34","doi-asserted-by":"crossref","unstructured":"E. P. Strecker, A. Gabelmann, and I. Boos .et al.Effect on intimal hyperplasia of dexamethasone released from coated metal stents compared with non-coated stents in canine femoral arteries., Cardiovasc Intervent Radiol, 1998 .21 :487 \u2013496 .","DOI":"10.1007\/s002709900309"},{"key":"i1545-1550-12-3-371-b35","doi-asserted-by":"crossref","unstructured":"D. H. Walter, V. Sch\u00e4chinger, and M. Elsner .et al.Effect of statin therapy on restenosis after coronary stent implantation., Am J Cardiol, 2000 .85 :962 \u2013968 .","DOI":"10.1016\/S0002-9149(99)00910-8"},{"key":"i1545-1550-12-3-371-b36","doi-asserted-by":"crossref","unstructured":"P. O. Bonetti, L. O. Lerman, and C. Napoli .et al.Statin effects beyond lipid lowering\u2014are they clinically relevant? Eur Heart J, 2003 .24 :225 \u2013248 .","DOI":"10.1016\/S0195-668X(02)00419-0"},{"key":"i1545-1550-12-3-371-b37","doi-asserted-by":"crossref","unstructured":"K. E. Porter, J. Naik, and N. A. Turner .et al.Simvastatin inhibits human saphenous vein neointima formation via inhibition of smooth muscle cell proliferation and migration., J Vasc Surg, 2002 .36 :150 \u2013157 .","DOI":"10.1067\/mva.2002.122029"},{"key":"i1545-1550-12-3-371-b38","doi-asserted-by":"crossref","unstructured":"B. Scheller, A. Schmitt, and M. B\u00f6hm .et al.Atorvastatin stent coating does not reduce neointimal proliferation after coronary stenting., Z Kardiol, 2003 .92 :1025 \u20131028 .","DOI":"10.1007\/s00392-003-1022-4"}],"container-title":["Journal of Endovascular Therapy"],"original-title":[],"language":"en","deposited":{"date-parts":[[2026,4,29]],"date-time":"2026-04-29T21:27:40Z","timestamp":1777498060000},"score":1,"resource":{"primary":{"URL":"http:\/\/jet.sagepub.com\/lookup\/doi\/10.1583\/05-1525.1"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2005,6]]},"references-count":38,"journal-issue":{"issue":"3","published-print":{"date-parts":[[2005,6]]}},"alternative-id":["10.1583\/05-1525.1"],"URL":"https:\/\/doi.org\/10.1583\/05-1525.1","relation":{},"ISSN":["1526-6028","1545-1550"],"issn-type":[{"value":"1526-6028","type":"print"},{"value":"1545-1550","type":"electronic"}],"subject":[],"published":{"date-parts":[[2005,6]]}}}