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Umetsu: Recent trend in agrochemical development focusing on fungicides, insecticides, acaricides, and nematicides. <i>Plant Protection<\/i> <b>77<\/b>, 666\u2013674 (2023), and <b>78<\/b>, 56\u201363 (2024) (in Japanese)."},{"key":"6","unstructured":"6) N. Umetsu and Y. Shirai: Recent trend in herbicide discovery studies. <i>Fine Chemical<\/i>s <b>53<\/b>, 38\u201347, 57\u201366 (2024) (in Japanese)."},{"key":"7","doi-asserted-by":"crossref","unstructured":"7) T. Yoneda, Y. Nakamura, S. Tsukuda, Y. Abe, M. Matsumoto and S. Mitani: Isofetamid: Discovery and optimization of a novel fungicide. In \u201cRecent Highlights in the Discovery and Optimization of Crop Protection Products,\u201d ed. by P. Maienfisch and S. Mangelinckx, Academic Press, pp. 391\u2013399, 2021.","DOI":"10.1016\/B978-0-12-821035-2.00027-9"},{"key":"8","doi-asserted-by":"crossref","unstructured":"8) K. Kikutake, T. Furuya, M. Hasebe, H. Nagai and M. Oda: Development of a novel fungicide, pyraziflumid. <i>J. Pestic. Sci.<\/i> <b>45<\/b>, 184\u2013190 (2020).","DOI":"10.1584\/jpestics.J20-02"},{"key":"9","unstructured":"9) https:\/\/investors.fmc.com\/news\/news-details\/2021\/FMC-Corporations-fluindapyr-fungicide-receives-U.S.-EPA-registration\/default.aspx (Accessed June 6, 2025)"},{"key":"10","unstructured":"10) https:\/\/www.fmc.com\/en\/articles\/fmc-corporation-and-corteva-agriscience-collaborate-provide-fluindapyr-fungicide (Accessed 6 June, 2025)"},{"key":"11","unstructured":"11) Sumitomo Chemical News Release, Feb. 25, 2019. https:\/\/www.sumitomo-chem.co.jp\/english\/news\/detail\/20190225e.html (Accessed 4 June, 2025)"},{"key":"12","doi-asserted-by":"crossref","unstructured":"12) S. Kiguchi, T. Inoue, Y. Matsuzaki, F. Iwahashi and H. Sakaguchi: Discovery and biological profile of inpyrfluxam: A new broad-spectrum succinate dehydrogenase inhibitor fungicide. In \u201cRecent Highlights in the Discovery and Optimization of Crop Protection Products,\u201d ed. by P. Maienfisch and S. Mangelinckx, Academic Press, pp. 381\u2013389, 2021.","DOI":"10.1016\/B978-0-12-821035-2.00026-7"},{"key":"13","doi-asserted-by":"crossref","unstructured":"13) A. Bartholomaeus, P. Dahmen, P. Desbordes, B. Essigmann, S. Gary, O. Gutbrod, J. Kleemann, P. Lancashire, M. Maue, H.-G. Schwarz and H. Tinwell: Isoflucypram\u2014the next-generation succinate dehydrogenase inhibitor fungicide. In \u201cRecent Highlights in the Discovery and Optimization of Crop Protection Products,\u201d ed. by P. Maienfisch and S. Mangelinckx, Academic Press, pp. 367\u2013380, 2021.","DOI":"10.1016\/B978-0-12-821035-2.00025-5"},{"key":"14","doi-asserted-by":"crossref","unstructured":"14) D. Stierli, H. U. Haas, R. Rajan, D. Bartlett, H. Sierotzki, F. Cederbaum, H. Walter and C. Lamberth: ADEPIDYN\u2014The first <i>N<\/i>-methoxy-substituted carboxamide among the succinate dehydrogenase inhibitors. In \u201cRecent Highlights in the Discovery and Optimization of Crop Protection Products,\u201d ed. by P. Maienfisch and S. Mangelinckx, Academic Press, pp. 357\u2013366, 2021.","DOI":"10.1016\/B978-0-12-821035-2.00024-3"},{"key":"15","unstructured":"15) Adepidyn<sup>\u00ae<\/sup> technology: a new generation fungicide\u2013Syngenta. https:\/\/www.syngenta.com\/products\/protecting-crops\/adepidyn (Accessed 5 June, 2025)"},{"key":"16","doi-asserted-by":"crossref","unstructured":"16) F. Ji, J. Zhang, X. Chen, B. Liu, A. Zhou, Y. Feng, J. Zhao, L. Huang, Z. Kang and G. Zhan: Effects of flubeneteram on inhibiting the development of <i>Puccinia striiformis<\/i> f. sp. <i>tritici<\/i> in wheat leaves. <i>J. Agric. Food Chem.<\/i> <b>71<\/b>, 5162\u20135171 (2023).","DOI":"10.1021\/acs.jafc.3c00499"},{"key":"17","unstructured":"17) A. Nishimura: Characteristics of the versatile fungicide picoxystrobin. <i>Plant Protection<\/i> <b>70<\/b>, 836\u2013838 (2016) (in Japanese)."},{"key":"18","unstructured":"18) K. Imanishi: Characteristics and usage of the fungicide mandestrobin. <i>Plant Protection<\/i> <b>70<\/b>, 710\u2013711 (2016) (in Japanese)."},{"key":"19","unstructured":"19) D. Hirotomi, N. Ueda, S. Kiguchi, M. Hirota, K. Iwashita and R. Kodaka: Research and development of a novel fungicide \u2018Mandestrobin.\u2019 <i>Sumitomo Kagaku<\/i> <b>2016<\/b>, 4\u201316 (2016) (in Japanese)."},{"key":"20","unstructured":"20) Y. Masuzaki, Y. Yoshimoto, S. Arimori, F. Iwahashi, M. Kurahashi, T. Toriumi, R. Ito, M. Kondo and M. Tabuchi: Discovery and development of a novel fungicide, Metyltetraprole, <i>Sumitomo Kagaku<\/i> (English Edition) <b>2024<\/b>, Report 2, 1\u201314 (2024). https:\/\/www.sumitomo-chem.co.jp\/english\/rd\/report\/2024E_2.pdf (Accessed 7 June, 2025)"},{"key":"21","doi-asserted-by":"crossref","unstructured":"21) Y. Matszaki, Y. Yoshimoto, S. Arimori and F. Iwahashi: The discovery of metyltetraprole: Reconstruction of the quinone outside inhibitor extended pharmacophore to overcome QoI-resistant Strains. In \u201cRecent Highlights in the Discovery and Optimization of Crop Protection Products,\u201d ed. by P. Maienfisch and S. Mangelinckx, Academic Press, pp. 425\u2013432, 2021.","DOI":"10.1016\/B978-0-12-821035-2.00029-2"},{"key":"22","unstructured":"22) https:\/\/chemrobotics.in\/agrochemical-discovery-update-june-2024-sumitomos-new-strobilurin-fungicide-bifemetstrobin-granted-provisional-iso-status\/ (Accessed 9 June, 2025)"},{"key":"23","unstructured":"23) https:\/\/chemrobotics.in\/new-iso-may-2025-metcyclofenstrobin-a-strobilurin-fungicide-by-syngenta\/ (Accessed 9 June, 2025)"},{"key":"24","doi-asserted-by":"crossref","unstructured":"24) W. J. Owen, C. Yao, K. Myung, G. Kemmitt, A. Leader, K. G. Meyer, A. J. Bowling, T. Slanec and V. J. Kramer: Biological characterization of fenpicoxamid, a new fungicide with utility in cereals and other crops. <i>Pest Manag. Sci.<\/i> <b>73<\/b>, 2005\u20132016 (2017).","DOI":"10.1002\/ps.4588"},{"key":"25","unstructured":"25) https:\/\/www.corteva.co.uk\/news-and-resources\/Corteva-Agriscience-Inatreq-Active-Approved-in-UK.html (Accessed 9 June, 2025)"},{"key":"26","doi-asserted-by":"crossref","unstructured":"26) K. G. Meyer, C. Yao, Y. Lu, K. Bravo-Altamirano, Z. Buchan, J. F. Daeuble, K. DeKorever, J. DeLorbe, R. Heemstra, J. Herrick, D. Jones, B. A. Loy, J. Rigoli, N. X. Wang, J. Wilmot and D. Young: The discovery of florylpicoxamid, a new picolinamide for disease control. In \u201cRecent Highlights in the Discovery and Optimization of Crop Protection Products,\u201d ed. by P. Maienfisch and S. Mangelinckx, Academic Press, pp. 433\u2013442, 2021.","DOI":"10.1016\/B978-0-12-821035-2.00030-9"},{"key":"27","unstructured":"27) March 28, 2023\/PRNewswire. https:\/\/investors.corteva.com\/news-releases\/news-release-details\/corteva-agriscience-launches-adavelttm-active-bringing-farmer (Accessed 11 June, 2025)"},{"key":"28","unstructured":"28) EPA 2025\/1\/16. https:\/\/www.epa.gov\/pesticides\/epa-announces-proposed-registration-new-pesticide-florylpicoxamid (Accessed 11 June, 2025)"},{"key":"29","unstructured":"29) Corteva News release 2022\/2\/10. https:\/\/www.corteva.com\/resources\/media-center\/corteva-announces-haviza-active-as-global-trademark-for-newest-active-ingredient-in-its-innovation-pipeline.html (Accessed 11 June, 2025)"},{"key":"30","unstructured":"30) https:\/\/homologa.com\/blog\/news\/argentina-new-fungicide\/ (Accessed June 11, 2025)"},{"key":"31","unstructured":"31) Y. Kuchii: The biological property on a new fungicide, mefentrifluconazole (Belanty<sup>\u00ae<\/sup> Flowable). <i>Plant Protection<\/i> <b>78<\/b>, 175\u2013177 (2024) (in Japanese)."},{"key":"32","unstructured":"32) M. Semar, D. Strobel, M. Coquiller, G. Stammler, J. Barnes, L. de Paula Collette and J. Lee: Revysol<sup>\u00ae<\/sup>: The new broad-spectrum fungicide of BASF SE. <i>Comm. Appl. Biol. Sci.<\/i> <i>Ghent University<\/i> <b>84<\/b>, 251 (2019)."},{"key":"33","unstructured":"33) S. Uchida: Properties of prothioconazole, a novel fungicide. <i>Plant Protection<\/i> <b>77<\/b>, 230\u2013235 (2023) (in Japanese)."},{"key":"34","doi-asserted-by":"crossref","unstructured":"34) B. Jiao, Y. Zhu, J. Xu, F. Dong, X. Wu, X. Liu and Y. Zheng: Identification and ecotoxicity prediction of pyrisoxazole transformation products formed in soil and water using an effective HRMS workflow. <i>J. Hazard. Mater.<\/i> <b>424<\/b>(Pt A), 127223 (2022).","DOI":"10.1016\/j.jhazmat.2021.127223"},{"key":"35","unstructured":"35) R. Kuwahara: Characteristics of the fungicide picarbutrazox. <i>Plant Protection<\/i> <b>72<\/b>, 208\u2013211 (2018) (in Japanese)."},{"key":"36","unstructured":"36) S. Watanabe, I. Urihara, T. Fujii, H. Yamanaka and H. Sano: Picarbutrazox: A novel fungicide for the control of oomycete disease. <i>Comm. Appl. Biol. Sci.<\/i> <i>Ghent University<\/i> <b>84<\/b>, 321 (2019)."},{"key":"37","doi-asserted-by":"crossref","unstructured":"37) H. Hagiwara, R. Ezaki, T. Hamada, M. Tsuda and K. Ebihara: Development of a novel fungicide, tolprocarb. <i>J. Pestic. Sci.<\/i> <b>44<\/b>, 208\u2013213 (2019).","DOI":"10.1584\/jpestics.J19-01"},{"key":"38","unstructured":"38) Y. Kuchii: Characteristics of the fungicide oxathiapiprolin. <i>Plant Protection<\/i> <b>70<\/b>, 418\u2013419 (2016) (in Japanese)."},{"key":"39","unstructured":"39) Zorvec\u2122 active Technical Bulletin. https:\/\/www.corteva.com\/content\/dam\/dpagco\/corteva\/global\/corporate\/general\/files\/active-ingredients\/ZOR.035.Corteva.Zorvec.Global.Technical.Bulletin.pdf (Accessed 17 May, 2025)"},{"key":"40","unstructured":"40) https:\/\/news.agropages.com\/News\/NewsDetail---42499.htm#:~:text=Bayer Australia and New Zealand&amp;text=The Australian Pesticides and Veterinary, in a suspension concentrate formulation (Accessed 17 June, 2025)"},{"key":"41","unstructured":"41) N. Myojo: Properties of dichlobentiazox (DISARTA\u2122), a novel fungicide. <i>Plant Protection<\/i> <b>74<\/b>, 671\u2013674 (2020) (in Japanese)."},{"key":"42","unstructured":"42) Agricultural Chemicals and Agriculture-Related Business (Japan). https:\/\/ir.kumiai-chem.co.jp\/en\/library\/csr\/main\/00\/teaserItems1\/06\/linkList\/04\/link\/P37-38_en.pdf (Accessed 17 June, 2025)"},{"key":"43","unstructured":"43) S. Fujii: Characteristics of KINOPROL<sup>\u00ae<\/sup> (ipflufenoquin), a novel fungicide. <i>Plant Protection<\/i> <b>77<\/b>, 164\u2013166 (2023) (in Japanese)."},{"key":"44","unstructured":"44) Nisso Press Release, Oct. 2023. https:\/\/www.nikkan.co.jp\/releases\/view\/163440 (in Japanese) (Accessed 17 June, 2025)"},{"key":"45","unstructured":"45) US EPA: Pesticide Product Label, Kinoprol 20 SC,03\/29\/2022. https:\/\/www3.epa.gov\/pesticides\/chem_search\/ppls\/008033-00139-20220329.pdf (Accessed 17 June, 2025)"},{"key":"46","doi-asserted-by":"crossref","unstructured":"46) H. Ito, T. Takada, M. Morimoto, H. Komai, F. Kajino, T. Ohara, Y. Tamagawa, M. Tsuda and S. Banba: Design and biological activity of a novel fungicide, quinofumelin. <i>J. Pestic. Sci.<\/i> <b>48<\/b>, 22\u201327 (2023).","DOI":"10.1584\/jpestics.D22-042"},{"key":"47","doi-asserted-by":"crossref","unstructured":"47) N. Higashimura, A. Hamada, T. Ohara, S. Sakurai, H. Ito and S. Banba: The target site of the novel fungicide quinofumelin, <i>Pyricularia oryzae<\/i> class II dihydroorotate dehydrogenase. <i>J. Pestic. Sci.<\/i> <b>47<\/b>, 190\u2013196 (2022).","DOI":"10.1584\/jpestics.D22-027"},{"key":"48","doi-asserted-by":"crossref","unstructured":"48) N. Higashimura, A. Hamada and S. Banba: Novel fungicide quinofumelin shows selectivity for fungal dihydroorotate dehydrogenase over the corresponding human enzyme. <i>J. Pestic. Sci.<\/i> <b>48<\/b>, 17\u201321 (2023).","DOI":"10.1584\/jpestics.D22-035"},{"key":"49","unstructured":"49) Mitsui Chemical News Release. https:\/\/jp.mitsuichemicals.com\/jp\/release\/2025\/2025_0212\/index.htm (in Japanese) (Accessed 17 June, 2025)"},{"key":"50","unstructured":"50) M. Kurahashi, Y. Matsuzaki, A. Manabe, M. Kawamura, F. Iwahashi, M. Yamane, R. Matsuyama and Y. Handa: Discovery and development of pyridachlometyl. <i>SUMITOMO KAGAKU<\/i> (English Edition) <b>Report 3<\/b>, 1\u201314 (2023)."},{"key":"51","doi-asserted-by":"crossref","unstructured":"51) Y. Matsuzaki, M. Kurahashi, S. Watanabe, S. Kiguchi, T. Harada and F. Iwahashi: Discovery and development of pyridachlometyl. <i>Pest Manag. Sci.<\/i> <b>81<\/b>, 2442\u20132449 (2025).","DOI":"10.1002\/ps.8239"},{"key":"52","unstructured":"52) Trade News, June 2, 2025. https:\/\/www.basf.com\/global\/en\/media\/news-releases\/2025\/06\/p-25-100 (Accessed 17 June, 2025)"},{"key":"53","unstructured":"53) Fluopimomide\u2014PubChem. https:\/\/pubchem.ncbi.nlm.nih.gov\/compound\/Fluopimomide"},{"key":"54","unstructured":"54) Fluopimomide\u2014AERU\u2014University of Hertfordshire. https:\/\/sitem.herts.ac.uk\/aeru\/ppdb\/en\/Reports\/3204.htm (Accessed 17 June, 2025)"},{"key":"55","unstructured":"55) M. Miyashita: Trends in exploratory study on peptide pesticides. In \u201cTrend in Research and Development of Chemical Pesticides, Biopesticides and Biostimulants,\u201d supervised by N. Umetsu, CMC Publishing, pp. 303-311, 2023 (in Japanese)."},{"key":"56","unstructured":"56) CEV, SA. https:\/\/www.agropages.com\/companydirectory\/Detail-18394.htm (Accessed 14 July, 2025)"},{"key":"57","unstructured":"57) ProBlad<sup>\u00ae<\/sup> Verde\u2014SymAgro. https:\/\/sym-agro.com\/our-products\/problad (Accessed 14 July, 2025)"},{"key":"58","unstructured":"58) CEV and Ceradis Sign Biofungicide R&amp;D Agreement. https:\/\/ceradis.com\/2020\/09\/29\/cev-and-ceradis-sign-biofungicide-rd-agreement\/ (Accessed 13 July, 2025)"},{"key":"59","unstructured":"59) Products-Plant Health Care plc. https:\/\/www.planthealthcare.com\/products (Accessed 19 June, 2025)"},{"key":"60","unstructured":"60) Plant Health Care: Biofungicide PHC279 Approved by US EPA. https:\/\/www.fmp-tv.co.uk\/2023\/03\/01\/plant-health-care-biofungicide-phc279-approved-by-us-epa\/ (Accessed 19 June, 2025)"},{"key":"61","unstructured":"61) Saori-Plant Health Care plc. https:\/\/www.planthealthcare.com\/products\/Saori (Accessed 19 June, 2025)"},{"key":"62","doi-asserted-by":"crossref","unstructured":"62) C.-Y. Huang, K. Araujo, J. N. S\u00e1nchez, G. Kund, J. Trumble, C. Roper, K. E. Godfrey and H. Jin: A stable antimicrobial peptide with dual functions of treating and preventing citrus Huanglongbing. <i>Proc. Natl. Acad. Sci. U.S.A.<\/i> <b>118<\/b>, e2019628118 (2021).","DOI":"10.1073\/pnas.2019628118"},{"key":"63","unstructured":"63) ADAMA Media Releases 06 May, 2025. https:\/\/www.adama.com\/en\/media-releases\/novel-active-ingredient-gilboa-introduces-new-mode-action (Accessed 22 June, 2025)"},{"key":"64","unstructured":"64) https:\/\/www.bcpc.org\/latest-news\/technical-news\/new-pesticide-names-added-to-bcpcs-online-pesticide-manual (Accessed 22 June, 2025)"},{"key":"65","unstructured":"65) https:\/\/chemrobotics.in\/iso-update-march-2021-9-new-agrochemical-candidates-published-including-benquitrione-shandong-cynda-herbicide-bipyrazone-qingdao-qingyuan-herbicide-cypyrafluone-kingagroot-herbicide\/ (Accessed 22 June, 2025)"},{"key":"66","doi-asserted-by":"crossref","unstructured":"66) L. Jin, X. Chen, C. Pang, L. Zhou, Y. Liu, Y. Sun, L. Xu, Y. Wang and Y. Chen: Investigation of the antibacterial mechanism of the novel bactericide dioctyldiethylenetriamine (Xinjunan). <i>Pest Manag. Sci.<\/i> <b>79<\/b>, 2780\u20132791 (2023).","DOI":"10.1002\/ps.7456"},{"key":"67","doi-asserted-by":"crossref","unstructured":"67) F. Li, K. Wang, X. Zhu, W. Liu, Y. Wu, D. Lv, Y. Han, X. Wang, D. Cheng, T. Chen, C. Xu and X. Sun: Chloroinconazide inhibits <i>Pseudomonas syringae<\/i> pv. <i>tabaci<\/i> causing tobacco wildfire disease by directly destroying bacteria and inducing oxidative damage. <i>Pestic. Biochem. Physiol.<\/i> <b>213<\/b>, 106476 (2025).","DOI":"10.1016\/j.pestbp.2025.106476"},{"key":"68","unstructured":"68) https:\/\/news.agropages.com\/news\/NewsDetail---52971.htm (Accessed 22 June, 2025)"},{"key":"69","doi-asserted-by":"crossref","unstructured":"69) S. Mochizuki, T. Fukumoto, T. Ohara, K. Ohtani, A. Yoshihara, Y. Shigematsu, K. Tanaka, K. Ebihara, S. Tajima, K. Gomi, K. Ichimura, K. Izumori and K. Akimitsu: The rare sugar d-tagatose protects plants from downy mildews and is a safe fungicidal agrochemical. <i>Commun. Biol.<\/i> <b>3<\/b>, 423 (2020).","DOI":"10.1038\/s42003-020-01133-7"},{"key":"70","unstructured":"70) https:\/\/chemrobotics.in\/agrochemical-discovery-1update-silvateams-new-pesticide-galquin-granted-provisional-iso-status\/ (Accessed 24 June, 2025)"},{"key":"71","unstructured":"71) https:\/\/chemrobotics.in\/agrochemical-discovery-update-july-2024-shandong-uniteds-new-quinolinone-bactericide-fluquinometoate-granted-provisional-iso-status-chemrobo\/ (Accessed 23 June, 2025)"},{"key":"72","unstructured":"72) R. Horikoshi and M. Tomizawa: Trend in development of nicotinic insecticides. In \u201cTrend in Pesticide Discovery Research\u2014Development of Safer and Environmentally Friendly Pesticides\u2014,\u201d supervised by N. Umetsu, CMC Publishing, pp. 104\u2013112, 2018 (in Japanese)."},{"key":"73","doi-asserted-by":"crossref","unstructured":"73) Y. Onozaki, R. Horikoshi, I. Ohno, S. Kitsuda, K. A. Durkin, T. Suzuki, C. Asahara, N. Hiroki, R. Komabashiri, R. Shimizu, M. Furutani, M. Ihara, K. Matsuda, M. Mitomi, S. Kagabu, K. Uomoto and M. Tomizawa: Flupyrimin: A novel insecticide acting at the nicotinic acetylcholine receptors. <i>J. Agric. Food Chem.<\/i> <b>65<\/b>, 7865\u20137873 (2017).","DOI":"10.1021\/acs.jafc.7b02924"},{"key":"74","unstructured":"74) M. Nakano, K. Fukatsu, R. Tanaka, H. Inui and Y. Yamashita: General trends in insecticide research and development. In \u201cTrend in Research and Development of Chemical Pesticides, Biopesticides and Biostimulants,\u201d supervised by N. Umetsu, CMC Publishing, pp. 69\u201383, 2023 (in Japanese)."},{"key":"75","unstructured":"75) Neonicotinoids\u2014European Commission. https:\/\/food.ec.europa.eu\/plants\/pesticides\/approval-active-substances-safeners-and-synergists\/renewal-approval\/neonicotinoids_en (Accessed 30 June, 2025)"},{"key":"76","doi-asserted-by":"crossref","unstructured":"76) G. B. Watson, M. W. Siebert, N. X. Wang, M. R. Loso and T. C. Sparks: Sulfoxaflor\u2014A sulfoximine insecticide: Review and analysis of mode of action, resistance and cross-resistance. <i>Pestic. Biochem. Physiol.<\/i> <b>178<\/b>, 104924 (2021).","DOI":"10.1016\/j.pestbp.2021.104924"},{"key":"77","unstructured":"77) Let\u2019s Talk About Flupyradifurone, Bayer Global. https:\/\/www.bayer.com\/en\/agriculture\/lets-talk-about-flupyradifurone (Accessed 30 June, 2025)"},{"key":"78","doi-asserted-by":"crossref","unstructured":"78) R. Nauen, P. Jeschke, R. Velten, M. E. Beck, U. Ebbinghaus-Kintscher, W. Thielert, K. W\u00f6lfel, M. Haas, K. Kunz and G. Raupach: Flupyradifurone: A brief profile of a new butenolide insecticide. <i>Pest Manag. Sci.<\/i> <b>71<\/b>, 850\u2013862 (2015).","DOI":"10.1002\/ps.3932"},{"key":"79","unstructured":"79) Pyraxalt\u2122 active Technical Bulletin. https:\/\/www.corteva.com\/content\/dam\/dpagco\/corteva\/global\/corporate\/general\/files\/active-ingredients\/Pyraxalt_Tech_Bulletin_2019_FINAL.pdf (Accessed 30 June, 2025)"},{"key":"80","unstructured":"80) https:\/\/www.corteva.jp\/content\/dam\/dpagco\/corteva\/as\/jp\/ja\/files\/flyer\/DOC-Lumispance_brochure_AP-JP.pdf (in Japanese) (Accessed 12 Sep., 2025)"},{"key":"81","unstructured":"81) T. Yamaga: Characteristics of the new insecticide \u201cDichloromezothiaz.\u201d <i>Plant Protection<\/i> <b>79<\/b>, 172\u2013176 (2025) (in Japanese)."},{"key":"82","unstructured":"82) https:\/\/www.zennoh.or.jp\/operation\/nouyaku\/fieldmast\/index.html (in Japanese) (Accessed 12 Sep., 2025)"},{"key":"83","unstructured":"83) Notice regarding launch of termite control agent \u201cNexus<sup>\u00ae<\/sup> Z800\u201d. https:\/\/www.nichino.co.jp\/contents\/000003556.pdf (in Japanese)"},{"key":"84","unstructured":"84) Trade News|February 6, 2025. https:\/\/www.basf.com\/global\/en\/media\/news-releases\/2025\/02\/p-25-002 (Accessed 1 July, 2025)"},{"key":"85","unstructured":"85) India Makes Landmark Registration of FENMEZODITIAZ. https:\/\/homologa.com\/blog\/news\/india-makes-landmark-registration-of-fenmezoditiaz-a-novel-technical-active-ingredient\/ (Accessed 1 July, 2025)"},{"key":"86","unstructured":"86) https:\/\/www.kingagroot.com\/En\/html\/news-25Aug05.html (Accessed 2 Sep., 2025)"},{"key":"87","unstructured":"87) Flupyrimin\/Mitsui Chemicals Crop &amp; Life Solutions, Inc. https:\/\/www.mc-croplifesolutions.com\/en\/randd\/active-ingredients\/flupyrimin\/ (Accessed 1 July, 2025)"},{"key":"88","doi-asserted-by":"crossref","unstructured":"88) M. Tsukamoto, T. Hamamoto, M. Morita, K. Nakamoto, A. Hisamatsu and T. Koyanagi: Cyclaniliprole: A novel diamide insecticide. In \u201cRecent highlights in the Discovery and Optimization of Crop Protection Products,\u201d ed. by P. Maienfisch and S. Mangelinckx, Academic Press, pp. 213\u2013219, 2021.","DOI":"10.1016\/B978-0-12-821035-2.00009-7"},{"key":"89","unstructured":"89) Insecticide-Cyclaniliprole (CYCLAPRYN\u2122). https:\/\/www.iskweb.co.jp\/eng\/products\/pdf\/international_Cyclaniliprole.pdf?0418 (Accessed 1 July, 2025)"},{"key":"90","unstructured":"90) M. Ataka: Characteristics of tetraniliprole, a novelinsecticide. <i>Plant Protection<\/i> <b>74<\/b>, 545\u2013550 (2020) (in Japanese)."},{"key":"91","unstructured":"91) R. Fischer, C. Funke, E. R. Gesing, N. Godley, C. Grondal, M. Heil, A. Hense, S. Kuebbeler, P. Loesel, O. Malsam, <i>et al<\/i>.: Discovery, synthesis and structure-activity relationship of tetraniliprole (Vayego\u2122), a novel diamide insecticide. <i>Comm. Appl. Biol. Sci<\/i>. <i>Ghent University<\/i> <b>84<\/b>, 227 (2019)."},{"key":"92","unstructured":"92) Tetraniliprole\u2014Minnesota Department of Agriculture. https:\/\/www.mda.state.mn.us\/sites\/default\/files\/docs\/2023-10\/tetraniliprolereview.pdf (Accessed 1 July, 2025)"},{"key":"93","doi-asserted-by":"crossref","unstructured":"93) Y. Liu, Y. Zhang, S. Liu, Y. L\u00fc, R. Lin, M. Li, X. Liao and X. Li: Distribution and degradation kinetics of cyhalodiamide in Chinese rice field environment. <i>Chin. J. Chem. Eng.<\/i> <b>26<\/b>, 2185\u20132191 (2018).","DOI":"10.1016\/j.cjche.2018.07.003"},{"key":"94","unstructured":"94) https:\/\/news.agropages.com\/News\/NewsDetail---45768.htm"},{"key":"95","doi-asserted-by":"crossref","unstructured":"95) M. Asahi, M. Kobayashi, T. Kagami, K. Nakahira, Y. Furukawa and Y. Ozoe: Fluxametamide: A novel isoxazoline insecticide that acts <i>via<\/i> distinctive antagonism of insect ligand-gated chloride channels. <i>Pestic. Biochem. Physiol.<\/i> <b>151<\/b>, 67\u201372 (2018).","DOI":"10.1016\/j.pestbp.2018.02.002"},{"key":"96","unstructured":"96) M. Inada and M. Asahi: Development trends of GABA-gated chloride channel allosteric modulators. In \u201cTrend in Research and Development of Chemical Pesticides, Biopesticides and Biostimulants,\u201d supervised by N. Umetsu, CMC Publishing, pp. 98\u2013107, 2023 (in Japanese)."},{"key":"97","unstructured":"97) M. Ando and H. Haruyama: Characteristics of the new insecticide, fluxametamide. <i>Plant Protection<\/i> <b>73<\/b>, 465\u2013468 (2019) (in Japanese)."},{"key":"98","doi-asserted-by":"crossref","unstructured":"98) T. Mita, Y. Furukawa, M. Iwasa, T. Kikuchi and M. Komoda: Studies on a novel insecticide, fluxametamide. In \u201cRecent highlights in the Discovery and Optimization of Crop Protection Products,\u201d ed. by P. Maienfisch and S. Mangelinckx, Academic Press, pp. 157\u2013163, 2021.","DOI":"10.1016\/B978-0-12-821035-2.00007-3"},{"key":"99","doi-asserted-by":"crossref","unstructured":"99) T. Nakao, H. Katsuta, M. Nomura, T. Wakita, H. Daido, Y. Kobayashi, A. Kawahara and S. Banba: Discovery and optimization of a novel insecticide, broflanilide. In \u201cRecent Highlights in the Discovery and Optimization of Crop Protection Products,\u201d ed. by P. Maienfisch and S. Mangelinckx, Academic Press, pp. 145\u2013155, 2021.","DOI":"10.1016\/B978-0-12-821035-2.00006-1"},{"key":"100","unstructured":"100) A. Naoi: Features of TENEBENAL<sup>\u00ae<\/sup> (broflanilide), A novel insecticide. <i>Plant Protection<\/i> <b>75<\/b>, 462\u2013467 (2021) (in Japanese)."},{"key":"101","unstructured":"101) Tenebenal\u2122\/Mitsui Chemicals Crop &amp; Life Solutions, Inc. https:\/\/www.mc-croplifesolutions.com\/en\/randd\/active-ingredients\/tenebenal\/ (Accessed 5 July, 2025)"},{"key":"102","unstructured":"102) Mitsui Chemicals, Inc. Press Releases. https:\/\/jp.mitsuichemicals.com\/en\/release\/2020\/2020_0917\/index.htm (Accessed 5 July, 2025)"},{"key":"103","doi-asserted-by":"crossref","unstructured":"103) J. Cassayre, T. Smejkal, J. Blythe, P. Hoegger, P. Renol, T. Pitterna, C. S. Prasanna, H. Smits, E. Godineau, T. Luksch, G. Berthon, G. Rawal, R. Patre, M. Lal, M. Boussemghoune, S. Masala, F. Barreteau, M. Flaeschel, J. Vogt and M. E. Qacemi: The discovery of isocycloseram: A novel isooxazoline insecticide. In \u201cRecent Highlights in the Discovery and Optimization of Crop Protection Products,\u201d ed. by P. Maienfisch and S. Mangelinckx, Academic Press, pp. 165\u2013212, 2021.","DOI":"10.1016\/B978-0-12-821035-2.00008-5"},{"key":"104","unstructured":"104) Syngenta US News. https:\/\/www.syngenta-us.com\/newsroom\/news_release_detail?id=227926 (Accessed 6 July, 2025)"},{"key":"105","unstructured":"105) https:\/\/news.agropages.com\/News\/NewsDetail---50726.htm#:~:text=Cyproflanilide was granted a patent,with a promising market prospect (Accessed 6 July, 2025)"},{"key":"106","unstructured":"106) https:\/\/www.uplcorp.com\/files\/corp_press_pdfs\/cd25b014150107183f55969d5cdfab37.pdf (Accessed 6 July, 2025)"},{"key":"107","unstructured":"107) Isoflualanam\u2014KingAgroot. https:\/\/www.kingagroot.com\/en\/html\/pdfShow.html?pdfUrl=Isoflualanam (Accessed 6 July, 2025)"},{"key":"108","unstructured":"108) T. Kashima, T. Kitamura, J. Ohnishi and T. Furuie: A novel insect behavior regulator, the feature and usage of acetylated glyceride. <i>Plant Protection<\/i> <b>73<\/b>, 594\u2013597 (2019) (in Japanese)."},{"key":"109","unstructured":"109) T. Kashima: Development of acetylated glyceride. In \u201cTrend in Research and Development of Chemical Pesticides, Biopesticides and Biostimulants,\u201d supervised by N. Umetsu, CMC Publishing, pp. 282\u2013293, 2023 (in Japanese)."},{"key":"110","doi-asserted-by":"crossref","unstructured":"110) M. Muehlebach, J. Schaetzer, A. Buchholz, A. J. Flemming, C. R. Godfrey, E. Godineau, M. Hamer, F. Vock-Hatt, O. Hueter, D. P. Kloer and Peter Maienfisch, S. Oliver, F. Perruccio, T. Pitterna, C. Popp, R. Senn, R. Slater, Tomas Smejkal, D. Stafford, J. Wenger, L. Wildsmith and W. Zambach: Spiropidion discovery: Broad spectrum control of sucking insects and mites for multicrop utility. In \u201cRecent Highlights in the Discovery and Optimization of Crop Protection Products,\u201d ed. by P. Maienfisch and S. Mangelinckx, Academic Press, pp. 241\u2013260, 2021.","DOI":"10.1016\/B978-0-12-821035-2.00012-7"},{"key":"111","unstructured":"111) https:\/\/www.syngenta.com\/media\/media-releases\/2020\/syngenta-crop-protection-announces-launch-spiropidion-new-insecticide (Accessed 7 July, 2025)"},{"key":"112","unstructured":"112) The first ketoenol crop protection product for foliar and soil uses. https:\/\/www.bayer.com\/en\/agriculture\/plenexos (Accessed 7 July, 2025)"},{"key":"113","unstructured":"113) Brazil\u2019s MAPA requests urgent review of Spidoxamat for citrus greening control. https:\/\/news.agropages.com\/News\/Detail-51897.htm (Accessed 7 July, 2025)"},{"key":"114","doi-asserted-by":"crossref","unstructured":"114) E. Satoh, R. Kasahara, K. Fukatsu, T. Aoki, H. Harayama and T. Murata: Benzpyrimoxan: Design, synthesis, and biological activity of a novel insecticide. <i>J. Pestic. Sci.<\/i> <b>46<\/b>, 109\u2013114 (2021).","DOI":"10.1584\/jpestics.D20-069"},{"key":"115","unstructured":"115) Mode of Action of Benzpyrimoxan\/IRAC. https:\/\/irac-online.org\/content\/uploads\/Mode-of-Action-of-Benzpyrimoxan-for-IRAC-proposal.pdf (Accessed 7 July, 2025)"},{"key":"116","unstructured":"116) T. Spear: Bioinsecticide-Evergreen Growers Supply, LLC. https:\/\/www.evergreengrowers.com\/spear-t-bioinsecticide.html (Accessed 8 July, 2025)"},{"key":"117","doi-asserted-by":"crossref","unstructured":"117) C. Chambers, P. Cutler, Y.-H. Huang, J. A. Goodchild, J. Blythe, C. K. Wang, A. Bigot, Q. Kaas, D. J. Craik, D. Sabbadin and F. G. Earley: Insecticidal spider toxins are high affinity positive allosteric modulators of the nicotinic acetylcholine receptor. <i>FEBS Lett.<\/i> <b>593<\/b>, 1336\u20131350 (2019).","DOI":"10.1002\/1873-3468.13435"},{"key":"118","unstructured":"118) Sero-X-Innovate Ag. https:\/\/innovate-ag.com.au\/sero-x\/ (Accessed 16 July, 2025)"},{"key":"119","doi-asserted-by":"crossref","unstructured":"119) T. Kobayashi, H. Hotta, T. Miyake, M. Nomura, R. Horikoshi and K. Yamamoto: Discovery of flometoquin, a novel quinoline insecticide. <i>J. Pestic. Sci.<\/i> <b>48<\/b>, 168\u2013174 (2023).","DOI":"10.1584\/jpestics.D23-035"},{"key":"120","doi-asserted-by":"crossref","unstructured":"120) H. Takeuchi, M. Nomura, R. Horikoshi, S. Aasano, T. Miyake, T. Kobayashi, M. Murai, Y. J. Chen, F. Earley, J. Mina and A. Crossthwaite: Y.-Ju Chen, F. Earley, J. Mina, J. Mina and A. Crossthwaite: Flometoquin, a novel insecticide, acts on mitochondrial complex III as a Qi inhibitor. <i>J. Pestic. Sci.<\/i> <b>49<\/b>, 203\u2013209 (2024).","DOI":"10.1584\/jpestics.D24-008"},{"key":"121","doi-asserted-by":"crossref","unstructured":"121) C. Koradin, H. Schr\u00f6der, K. Oyama and S. \u014cmura: Chemistry and biology connected: The development of Inscalis. In \u201cRecent Highlights in the Discovery and Optimization of Crop Protection Products,\u201d ed. by P. Maienfisch and S. Mangelinckx, Academic Press, pp. 231\u2013239, 2021.","DOI":"10.1016\/B978-0-12-821035-2.00011-5"},{"key":"122","doi-asserted-by":"crossref","unstructured":"122) R. Horikoshi, K. Goto, M. Mitomi, T. Sunazuka and S. \u014cmura: Research and development of an insecticide, afidopyropen. <i>J. Pestic. Sci.<\/i> <b>50<\/b>, 14\u201317 (2025).","DOI":"10.1584\/jpestics.J25-01"},{"key":"123","doi-asserted-by":"crossref","unstructured":"123) M. Kamezaki, J. Otsuki and K. Natsuhara: Insecticidal activity against rice pest of oxazosulfyl, a novel sulfyl insecticide. <i>J. Pestic. Sci.<\/i> <b>49<\/b>, 31\u201337 (2024).","DOI":"10.1584\/jpestics.D23-057"},{"key":"124","doi-asserted-by":"crossref","unstructured":"124) M. Ito, Y. Nokura, M. Takahashi, M. Kamezaki, E. Sakamoto and S. Nishimura: Development of the insecticide oxazosulfyl. <i>J. Pestic. Sci.<\/i> <b>50<\/b>, 96\u2013101 (2025).","DOI":"10.1584\/jpestics.J25-02"},{"key":"125","doi-asserted-by":"crossref","unstructured":"125) J. Goodchild, Y. J. Chen, J. Blythe, L. C. Firth, E. Hirst, K. Bess, J. Bristow, J. Willis, R. Baines, F. Cash, M. Muehlebach, A. Buchholz, S. Rendler, F. Earley and A. Crossthwaite: A novel class of insecticidal alkylsulfones are potent inhibitors of vesicular acetylcholine transport. <i>Pestic. Biochem. Physiol.<\/i> <b>201<\/b>, 105854 (2024).","DOI":"10.1016\/j.pestbp.2024.105854"},{"key":"126","doi-asserted-by":"crossref","unstructured":"126) R. Yasunaga, M. Nakano, T. Kyuma, K. Fujii, H. Inui, J. Akutsu, I. Yonemura, T. Inoue, A. Suwa, T. Yoshizane, A. Nakao and Y. Mori: A novel insecticide cybenzoxasulfyl potently binds to vesicular acetylcholine transporter and disrupts the storage and release of acetylcholine in insects. <i>Biochem. Biophys. Res. Commun.<\/i> <b>763<\/b>, 151792 (2025).","DOI":"10.1016\/j.bbrc.2025.151792"},{"key":"127","doi-asserted-by":"crossref","unstructured":"127) J. D. Eckelbarger, M. H. Parker, M. C. Yap, A. M. Buysse, J. M. Babcock, R. Hunter, Y. Adelfinskaya, J. G. Samaritoni, N. Garizi and T. K. Trullinger: Synthesis and biological activity of a new class of insecticides: the N-(5-aryl-1,3,4-thiadiazol-2-yl)amides. <i>Pest Manag. Sci.<\/i> <b>73<\/b>, 761\u2013773 (2017).","DOI":"10.1002\/ps.4359"},{"key":"128","unstructured":"128) Tyclopyrazoflor is expected to do very well when it comes to market. https:\/\/www.echemi.com\/cms\/1747858.html (Accepted 22 May, 2025)"},{"key":"129","doi-asserted-by":"crossref","unstructured":"129) W. Zhang, R. D. Slack, M. A. Rossi, J. Hamm, D. Cordova, D. Clark, G. Lahm, M. Kar, K. Sana, M. Xu, A. DeAngelis and B. Frag: The discovery of indazapyroxamet: A novel 3-pyridinyl insecticide targeting piercing\/sucking insects. <i>Pest Manag. Sci.<\/i> <b>81<\/b>, 2419\u20132423 (2024).","DOI":"10.1002\/ps.8259"},{"key":"130","unstructured":"130) FMC highlights new products in meeting with shareholders. https:\/\/revistacultivar.com\/news\/fmc-highlights-new-products-in-meeting-with-shareholders (Accepted 22 May, 2025)"},{"key":"131","doi-asserted-by":"crossref","unstructured":"131) P. Maienfisch and K. Koerber: Recent innovations in crop protection research. <i>Pest Manag. Sci.<\/i> <b>81<\/b>, 2406\u20132418 (2025).","DOI":"10.1002\/ps.8441"},{"key":"132","doi-asserted-by":"crossref","unstructured":"132) D. Hodges: Discovery, research and development of axalion<sup>\u00ae<\/sup> active insecticide: Dimpropyridaz. <i>Pest Manag. Sci.<\/i> <b>81<\/b>, 2529\u20132534 (2025).","DOI":"10.1002\/ps.8385"},{"key":"133","doi-asserted-by":"crossref","unstructured":"133) C. Spalthoff, V. L. Salgado, N. Balu, M. D. David, P. Hehlert, H. Huang, J. E. Jones, R. Kandasamy, G. A. Knudsen, K. R. Lelito, J. B. Machamer, A. Nesterov, M. Tomalski, G. D. Wahl, B. J. Wedel and M. C. G\u00f6pfert: The novel pyridazine pyrazolecarboxamide insecticide dimpropyridaz inhibits chordotonal organ function upstream of TRPV channels. <i>Pest Manag. Sci.<\/i> <b>79<\/b>, 1635\u20131649 (2023).","DOI":"10.1002\/ps.7352"},{"key":"134","doi-asserted-by":"crossref","unstructured":"134) C. Parmentier, A. Baze, M. Untrau, A. Kampkoetter, D. Lasserre and L. Richert: Evaluation of human relevance of nicofluprole-induced rat thyroid disruption. <i>Toxicol. Appl. Pharmacol.<\/i> <b>435<\/b>, 115831 (2022).","DOI":"10.1016\/j.taap.2021.115831"},{"key":"135","doi-asserted-by":"crossref","unstructured":"135) S. Hashiro and H. Yasueda: RNA interference-based pesticides and antiviral agents: Microbial overproduction systems for double-stranded RNA for applications in agriculture and aquaculture. <i>Appl. Sci. (Basel)<\/i> <b>12<\/b>, 2954 (2022).","DOI":"10.3390\/app12062954"},{"key":"136","unstructured":"136) Index of New ISO Common Names \u201cledprona\u201d. http:\/\/www.bcpcpesticidecompendium.org\/index_new_frame.html (Accepted 22 Jun, 2025)"},{"key":"137","unstructured":"137) https:\/\/www.epa.gov\/pesticides\/epa-registers-novel-pesticide-technology-potato-crops (Accessed 1 July, 2025)"},{"key":"138","doi-asserted-by":"crossref","unstructured":"138) T. Furuya, K. Machiya, S. Fujioka, M. Nakano and K. Inagaki: Development of a novel acaricide, pyflubumide. <i>J. Pestic. Sci.<\/i> <b>42<\/b>, 132\u2013136 (2017).","DOI":"10.1584\/jpestics.J17-02"},{"key":"139","unstructured":"139) Technical information. https:\/\/www.nichino.co.jp\/contents\/000003079.pdf (Accessed 16 July, 2025)"},{"key":"140","doi-asserted-by":"crossref","unstructured":"140) J. Ouyang, Y. Tian, C. Jiang, Q. Yang, H. Wang and Q. Li: Laboratory assays on the effects of a novel acaricide, SYP-9625 on <i>Tetranychus cinnabarinus<\/i> (Boisduval) and its natural enemy, <i>Neoseiulus californicus<\/i> (McGregor). <i>PLoS One<\/i> <b>13<\/b>, e0199269 (2018).","DOI":"10.1371\/journal.pone.0199269"},{"key":"141","unstructured":"141) N. Hayashi: Development of formulated oil. In \u201cTrend in Research and Development of Chemical Pesticides, Biopesticides and Biostimulants,\u201d supervised by N. Umetsu, CMC Publishing, pp. 294\u2013302, 2023 (in Japanese)."},{"key":"142","doi-asserted-by":"crossref","unstructured":"142) N. Takeda, A. Takata, Y. Arai, K. Sasaya, S. Noyama, S. Wakisaka, N. A. Ghazy, D. Voigt and T. Suzuki: A vegetable oil-based biopesticide with ovicidal activity against the two-spotted spidermite, <i>Tetranychus urticae<\/i> Koch. <i>Eng. Life Sci.<\/i> <b>20<\/b>, 525\u2013534 (2020).","DOI":"10.1002\/elsc.202000042"},{"key":"143","unstructured":"143) Agrochemicals Business. https:\/\/www.nipponkayaku.co.jp\/english\/business\/life-science\/agrochemicals\/ (Accessed 25 July, 2025)"},{"key":"144","doi-asserted-by":"crossref","unstructured":"144) I. Hamamoto, M. Kawaguchi, T. Nakamura, M. Yano, K. Koizumi and J. Takahashi: Discovery of a novel acaricide, acynonapyr. <i>J. Pestic. Sci.<\/i> <b>48<\/b>, 202\u2013210 (2023).","DOI":"10.1584\/jpestics.D23-028"},{"key":"145","doi-asserted-by":"crossref","unstructured":"145) K. Hirata, K. Kudo, T. Amano and M. Kawaguchi: Effects of the novel acaricide acynonapyr on the calcium-activated potassium channel. <i>Pestic. Biochem. Physiol.<\/i> <b>204<\/b>, 106074 (2024).","DOI":"10.1016\/j.pestbp.2024.106074"},{"key":"146","doi-asserted-by":"crossref","unstructured":"146) S. Yoshimura and S. Mukawa: Characteristics biological activities of the novel acaricide flupentiofenox against phytophagous mites. <i>J. Pestic. Sci.<\/i> <b>48<\/b>, 211\u2013217 (2023).","DOI":"10.1584\/jpestics.D23-033"},{"key":"147","doi-asserted-by":"crossref","unstructured":"147) C. Uchiyama, S. Yoshimura, S. Yamamoto, M. Ogawa and K. Kawai: Acaricide flupentiofenox inhibits the mitochondrial \u03b2-oxidation pathway of fatty acids. <i>J. Agric. Food Chem.<\/i> <b>72<\/b>, 18391\u201318400 (2024).","DOI":"10.1021\/acs.jafc.4c03076"},{"key":"148","unstructured":"148) Index of New ISO Common Names \u201cvadescana\u201d. http:\/\/www.bcpcpesticidecompendium.org\/index_new_frame.html (Accessed 25 July, 2025)"},{"key":"149","unstructured":"149) EPA Proposes to Register New Pesticide for Varroa Mite Control. https:\/\/www.epa.gov\/pesticides\/epa-proposes-register-new-pesticide-varroa-mite-control (Accessed 10 Aug., 2025)"},{"key":"150","unstructured":"150) T. Sasami: Trends in the development of nematicides and the practice of nematode control. In \u201cTrend in Research and Development of Chemical Pesticides, Biopesticides and Biostimulants,\u201d supervised by N. Umetsu, CMC Publishing, pp. 140\u2013160, 2023 (in Japanese)."},{"key":"151","doi-asserted-by":"crossref","unstructured":"151) A. S. S. Schleker, M. Rist, C. Matera, A. Damijonaitis, U. Collienne, K. Matsuoka, S. S. Habash, K. Twelker, O. Gutbrod, C. Saalw\u00e4chter, M. Windau, S. Matthiesen, T. Stefanovska, M. Scharwey, M. T. Marx, S. Geibel and F. M. W. Grundler: Mode of action of fluopyram in plant-parasitic nematodes. <i>Sci. Rep.<\/i> <b>12<\/b>, 11954 (2022).","DOI":"10.1038\/s41598-022-15782-7"},{"key":"152","unstructured":"152) Bayer stops sale of NemaStrike for 2020. https:\/\/www.farmprogress.com\/business\/bayer-stops-sale-of-nemastrike-for-2020 (Accessed 28 July, 2025)"},{"key":"153","unstructured":"153) Reklemel active Technical bulletin. https:\/\/www.corteva.com\/content\/dam\/dpagco\/corteva\/global\/corporate\/files\/products-and-services\/DOC-Reklemel_active_tech_bull_2022_Final_Print-Global.pdf (Accessed 28 July, 2025)"},{"key":"154","doi-asserted-by":"crossref","unstructured":"154) J. Kearn, E. Ludlow, J. Dillon, V. O\u2019Connor and L. Holden-Dye: Fluensulfone is a nematicide with a mode of action distinct from anticholinesterases and macrocyclic lactones. <i>Pestic. Biochem. Physiol.<\/i> <b>109<\/b>, 44\u201357 (2014).","DOI":"10.1016\/j.pestbp.2014.01.004"},{"key":"155","unstructured":"155) NIMITZ<sup>\u00ae<\/sup>-ADAMA Ltd. https:\/\/www.adama.com\/new-zealand\/sites\/adama_new_zealand\/files\/product-documents\/2024-08\/Nimitz TechNote_Final_24.pdf (Accessed 28 July, 2025)"},{"key":"156","unstructured":"156) Nemguard SC, Ecospray. https:\/\/ecospray.com\/wp-content\/uploads\/2019\/07\/Ecospray-Nemguard-SC-Brochure.pdf (Accessed 28 July, 2025)"},{"key":"157","unstructured":"157) Cedroz\/Eastman. https:\/\/www.eastman.com\/en\/products\/product-detail\/71111396\/cedroz (Accessed 28 July, 2025)"},{"key":"158","doi-asserted-by":"crossref","unstructured":"158) H. Thompson, F. J. Peris-Felipo, N. Peranginangin, M. Pocock and A. L. Gayan-Quijano: Cyclobutrifluram (TYMIRIUM<sup>\u00ae<\/sup> technology): Low risks of a soil applied nematicide and fungicide to non-target soil invertebrates and bees. <i>Crop Prot.<\/i> <b>184<\/b>, 106822 (2024).","DOI":"10.1016\/j.cropro.2024.106822"},{"key":"159","doi-asserted-by":"crossref","unstructured":"159) A. Flemming, M. Guest, T. Luksch, A. O\u2019Sullivan, C. Screpanti, R. Dumeunier, M. Gaberth\u00fcel, E. Godineau, P. Harlow, A. Jeanguenat, B. Kurtz, P. Maienfisch, R. Mondi\u00e8re, A. Pierce, B. Slaats, T. Smejkal and O. Loiseleur: The discovery of Cyclobutrifluram, a new molecule with powerful activity against nematodes and diseases. <i>Pest Manag. Sci.<\/i> <b>81<\/b>, 2480\u20132490 (2025).","DOI":"10.1002\/ps.8730"},{"key":"160","unstructured":"160) https:\/\/news.agropages.com\/News\/Detail-47875.htm (Accessed 28 July, 2025)"},{"key":"161","unstructured":"161) The new HRAC Mode of Action Classification System for Herbicides. https:\/\/hracglobal.com\/europe\/files\/HRAC-Classification-System-2021_English.pdf (Accessed 3 Aug., 2025)"},{"key":"162","unstructured":"162) S. Murakami, D. Itaya, Y. Lyu and Ki. Kawai: Trend of herbicide development. In \u201cTrend in Research and Development of Chemical Pesticides, Biopesticides and Biostimulants,\u201d supervised by N. Umetsu, CMC Publishing, pp.161\u2013192, 2023 (in Japanese)."},{"key":"163","unstructured":"163) 2024-hrac-global-herbicide-moa-classification. https:\/\/hracglobal.com\/files\/2024-HRAC-GLOBAL-HERBICIDE-MOA-CLASSIFICATION-POSTERold.pdf (Accessed 3 Aug., 2025)"},{"key":"164","doi-asserted-by":"crossref","unstructured":"164) K. Sugiura, T. Yamaoka, M. Ito, R. Okabayashi, S. Shirakura and B. Shakudo: Development of a rice herbicide, triafamone. <i>J. Weed Sci. Tech<\/i> <b>66<\/b>, 72\u201376 (2021) (in Japanese).","DOI":"10.3719\/weed.66.72"},{"key":"165","doi-asserted-by":"crossref","unstructured":"165) A. Nagamatsu, K. Ueda, R. Tamai, S. Tani and S. Yamamoto: Development of a rice herbicide, fenquinotrione. <i>J. Pestic. Sci.<\/i> <b>47<\/b>, 139\u2013145 (2022).","DOI":"10.1584\/jpestics.J22-02"},{"key":"166","doi-asserted-by":"crossref","unstructured":"166) S. Yamamoto, Y. Tanetani, C. Uchiyama, A. Nagamatsu, M. Kobayashi, M. Ikeda and K. Kawai: Mechanism of action and selectivity of a novel herbicide, fenquinotrione. <i>J. Pestic. Sci.<\/i> <b>46<\/b>, 249\u2013257 (2021).","DOI":"10.1584\/jpestics.D21-019"},{"key":"167","unstructured":"167) M. Miyashita, T. Suganuma, Y. Kobayshi, K. Izakura and M. Sano: Studies on a new herbicide, lancotrione-sodium salt, Part 1. <i>Abstracts of the 45th Annual Meeting of the Pesticide Science Society of Japan<\/i>, p. 79 (2020) (in Japanese)."},{"key":"168","doi-asserted-by":"crossref","unstructured":"168) M. Tsukamoto, H. Kikugawa, S. Nagayama, T. Suganuma, T. Okita and H. Miyamoto: Discovery and structure optimization of a novel corn herbicide, tolpyralate. <i>J. Pestic. Sci.<\/i> <b>46<\/b>, 152\u2013159 (2021).","DOI":"10.1584\/jpestics.D20-031"},{"key":"169","unstructured":"169) Tolpyralate. https:\/\/www.iskweb.co.jp\/eng\/products\/pdf\/international_Tolpyralate.pdf?0418 (Accessed 12 Aug., 2025)"},{"key":"170","unstructured":"170) Bipyrazone\u2014KingAgroot. https:\/\/www.kingagroot.com\/en\/html\/pdfShow.html?pdfUrl=Bipyrazone (Accessed 13 Aug., 2025)"},{"key":"171","unstructured":"171) Cypyrafluone\u2014KingAgroot. https:\/\/www.kingagroot.com\/en\/assets\/pdf\/Cypyrafluone.pdf (Accessed 13 Aug., 2025)"},{"key":"172","unstructured":"172) Fenpyrazone\u2014KingAgroot. https:\/\/www.kingagroot.com\/en\/assets\/pdf\/Fenpyrazone.pdf (Accessed 15 Aug., 2025)"},{"key":"173","unstructured":"173) Tripyrasulfone\u2014KingAgroot. https:\/\/www.kingagroot.com\/en\/assets\/pdf\/Tripyrasulfone.pdf (Accessed 15 Aug., 2025)"},{"key":"174","doi-asserted-by":"crossref","unstructured":"174) R.-Yu Qu, J.-Xu Nan, Y.-Chao Yan, H.-Yan Lin, W.-Chao Yang and G.-Fu Yang: \u201cQuinazoline-2,4-dione: A promising scaffold for herbicide discovery. In \u201cRecent Highlights in the Discovery and Optimization of Crop Protection Products,\u201d ed. by P. Maienfisch and S. Mangelinckx, Academic Press, pp. 483\u2013499, 2021.","DOI":"10.1016\/B978-0-12-821035-2.00036-X"},{"key":"175","doi-asserted-by":"crossref","unstructured":"175) T. Nishio, N. Nishijima, T. Kubota, Y. Furuhata, Y. Nanao, H. Permana, T. Furuhashi and Y. Kato: Mechanism of herbicidal action and rice selectivity of iptriazopyrid: A novel azole carboxamide-based inhibitor of 4-hydroxyphenylpyruvate dioxygenase. <i>J. Agric. Food Chem.<\/i> <b>73<\/b>, 15950\u201315958 (2025).","DOI":"10.1021\/acs.jafc.4c11831"},{"key":"176","unstructured":"176) Mechanism of action of the rice herbicide \u201ciptriazopyrid\u201d elucidated. https:\/\/www.nissanchem.co.jp\/eng\/news_release\/release\/en2025_06_11.pdf (Accessed 15 Aug., 2025)"},{"key":"177","unstructured":"177) Flusulfinam\u2014KingAgroot. https:\/\/www.kingagroot.com\/en\/assets\/pdf\/Flusulfinam.pdf (Accessed 15 Aug., 2025)"},{"key":"178","unstructured":"178) https:\/\/news.agropages.com\/News\/NewsDetail---47391.htm (Accessed 15 Aug., 2025)"},{"key":"179","unstructured":"179) Cynda\u2019s patented herbicide pyraquinate released to market. https:\/\/news.agropages.com\/News\/NewsDetail---53281.htm (Accessed 15 Aug., 2025)"},{"key":"180","unstructured":"180) FarmHannong launches novel nonselective herbicide Tiafenacil in South Korea. https:\/\/news.agropages.com\/News\/NewsDetail---28263.htm (Accessed 16 Aug., 2025)"},{"key":"181","doi-asserted-by":"crossref","unstructured":"181) M. Witschel, R. Aponte, G. Armel, P. Bowerman, T. Mietzner, T. Newton, A. Porri, A. Simon and T. Seitz: Tirexor<sup>\u00ae<\/sup>\u2014design of a new resistance breaking protoporphyrinogen IX oxidase inhibitor. In \u201cRecent Highlights in the Discovery and Optimization of Crop Protection Products,\u201d ed. by P. Maienfisch and S. Mangelinckx, Academic Press, pp. 501\u2013509, 2021.","DOI":"10.1016\/B978-0-12-821035-2.00037-1"},{"key":"182","unstructured":"182) https:\/\/biologicaldiversity.org\/w\/news\/press-releases\/basf-to-stop-selling-pesticide-trifludimoxazin-rather-than-continue-litigation-2022-02-23\/ (Accessed 16 Aug., 2025)"},{"key":"183","unstructured":"183) https:\/\/www.epa.gov\/pesticides\/epa-announces-proposed-registration-pesticide-trifludimoxazin (Accessed 16 Aug., 2025)"},{"key":"184","doi-asserted-by":"crossref","unstructured":"184) Y. Sada, Y. Jin, M. Hikosaka and K. Ido: Epyrifenacil, a new systemic PPO-inhibiting herbicide for broad-spectrum weed control. <i>Pest Manag. Sci.<\/i> <b>81<\/b>, 2463\u20132468 (2024).","DOI":"10.1002\/ps.8244"},{"key":"185","unstructured":"185) Business &amp; Products\/SUMITOMO CHEMICAL. https:\/\/www.sumitomo-chem.co.jp\/english\/news\/detail\/20240725e.html (Accessed 17 Aug., 2025)"},{"key":"186","unstructured":"186) Flufenoximacil\u2013KingAgroot. https:\/\/www.kingagroot.com\/en\/assets\/pdf\/Flufenoximacil.pdf (Accessed 17 Aug., 2025)"},{"key":"187","doi-asserted-by":"crossref","unstructured":"187) M. Fujinami, Y. Takahashi, Y. Tanetani, M. Ito and M. Nasu: Development of a rice herbicide, fenoxasulfone. <i>J. Pestic. Sci.<\/i> <b>44<\/b>, 282\u2013289 (2019).","DOI":"10.1584\/jpestics.J19-04"},{"key":"188","doi-asserted-by":"crossref","unstructured":"188) T. Furuhashi, M. Otani and M. Iwasa: Dimesulfazet, a novel rice paddy herbicide, is an inhibitor of very long-chain fatty acid biosynthesis. <i>J. Pestic. Sci.<\/i> <b>49<\/b>, 77\u201386 (2024).","DOI":"10.1584\/jpestics.D23-036"},{"key":"189","unstructured":"189) Presentation for R&amp;D. https:\/\/www.nissanchem.co.jp\/eng\/news_release\/release\/en2025_06_16.pdf (Accessed 18 Aug., 2025)"},{"key":"190","unstructured":"190) Technical Bulletin. https:\/\/www.corteva.com\/content\/dam\/dpagco\/corteva\/global\/corporate\/general\/files\/active-ingredients\/DF_Arylex-TechBulletin_1-29-19.pdf (Accessed 20 Aug., 2025)"},{"key":"191","unstructured":"191) Broadleaf Weed Control in Multiple Crops\/Arylex Active. https:\/\/www.corteva.com\/products-and-services\/arylex.html (Accessed 20 Aug., 2025)"},{"key":"192","doi-asserted-by":"crossref","unstructured":"192) R. Herrera, M. R. Weimer, M. Morell, P. L. Havens, G. Meregalli, S. Papineni, L. A. Laughlin and G. Shan: Rinskor active herbicide-A new environment-friendly tool for weed management in rice and aquatic environments. In \u201cRecent Highlights in the Discovery and Optimization of Crop Protection Products,\u201d ed. by P. Maienfisch and S. Mangelinckx, Academic Press, pp. 511\u2013523, 2021.","DOI":"10.1016\/B978-0-12-821035-2.00038-3"},{"key":"193","doi-asserted-by":"crossref","unstructured":"193) V. V. Zakharychev and A. M. Martsynkevich: Development of novel pyridine-based agrochemicals: A review. <i>Adv. Agrochem.<\/i> <b>4<\/b>, 30\u201348 (2025).","DOI":"10.1016\/j.aac.2024.10.002"},{"key":"194","unstructured":"194) https:\/\/www.corteva.com\/resources\/media-center\/corteva-announces-bexoveld-active-as-global-brand-for-newest-active-ingredient.html (Accessed 20 Aug., 2025)"},{"key":"195","unstructured":"195) Fluchloraminopyr-tefuryl-KingAgroot. https:\/\/www.kingagroot.com\/en\/assets\/pdf\/Fluchloraminopyr-tefuryl.pdf (Accessed 20 Aug., 2025)"},{"key":"196","unstructured":"196) https:\/\/news.agropages.com\/News\/NewsDetail---45926.htm (Accessed August 20, 2025)"},{"key":"197","unstructured":"197) Isoflex\u2122 Active Overview\/FMC Crop. https:\/\/www.fmc.com\/en\/isoflexactive (Accessed 21 Aug., 2025)"},{"key":"198","unstructured":"198) Broclozone-KingAgroot. https:\/\/www.kingagroot.com\/en\/assets\/pdf\/Broclozone.pdf (Accessed 21 Aug., 2025)"},{"key":"199","doi-asserted-by":"crossref","unstructured":"199) J. Leipner and N. Ruta: Discovery of anisiflupurin, an inhibitor of cytokinin dehydrogenase that mitigates heat-induced yield reduction in rice. <i>Pest Manag. Sci.<\/i> <b>81<\/b>, 2662\u20132670 (2025).","DOI":"10.1002\/ps.8350"},{"key":"200","unstructured":"200) https:\/\/news.agropages.com\/News\/NewsDetail---48009.htm (Accessed 21 Aug., 2025)"},{"key":"201","doi-asserted-by":"crossref","unstructured":"201) J. N. Scutt, N. J. Willetts, B. F. Campos, S. Oliver, A. Hennessy, P. M. Joyce, S.-J. Hutchings, G. le Goupil, W. L. Colombo and S. S. Kaundun: Metproxybicyclone, a novel carbocyclic aryl-dione acetyl-CoA carboxylase-inhibiting herbicide for the management of sensitive and resistant grass weeds. <i>J. Agric. Food Chem.<\/i> <b>72<\/b>, 21380\u201321392 (2024).","DOI":"10.1021\/acs.jafc.4c02729"},{"key":"202","unstructured":"202) Major breakthrough in fight against resistant grass weeds. https:\/\/www.syngenta.com\/media\/media-releases\/2025\/major-breakthrough-fight-against-resistant-grass-weeds (Accessed 24 Aug., 2025)"},{"key":"203","unstructured":"203) CYNDA\u2019s innovative herbicide Feproxydim officially obtained the ISO general name, is expected to be launched in 2024. https:\/\/www.echemi.com\/cms\/1877498.html (Accessed 24 Aug., 2025)"},{"key":"204","doi-asserted-by":"crossref","unstructured":"204) K.-B. Haaf, O. Peters, B. Laber, G. Lange, E. Gatzweiler, S. Geibel, D. Passon, A. Endler, S. Lange, S. Kahlau, T. Eroschenko, P. Waldraff and P. L\u00fcmmen: The novel herbicide icafolin-methyl is a plant-specific inhibitor of tubulin polymerization. <i>Pest Manag. Sci.<\/i> <b>81<\/b>, 2652\u20132661 (2024).","DOI":"10.1002\/ps.8415"},{"key":"205","unstructured":"205) https:\/\/www.bayer.com\/media\/en-us\/bayer-submits-registration-applications-for-novel-herbicide-in-four-major-markets\/ (Accessed 24 Aug., 2025)"},{"key":"206","doi-asserted-by":"crossref","unstructured":"206) R. Campe, E. Hollenbach, L. K\u00e4mmerer, J. Hendriks, H. W. H\u00f6ffken, H. Kraus, J. Lerchl, T. Mietzner, S. Tresch, M. Witschel and J. Hutzler: A new herbicidal site of action: Cinmethylin binds to acyl-ACP thioesterase and inhibits plant fatty acid biosynthesis. <i>Pestic. Biochem. Physiol.<\/i> <b>148<\/b>, 116\u2013125 (2018).","DOI":"10.1016\/j.pestbp.2018.04.006"},{"key":"207","unstructured":"207) https:\/\/www.basf.com\/hk\/en\/media\/news-releases\/anz\/2019\/11\/BASF-introduces-Luximax-to-Australian-farmers.html (Accessed 25 Aug., 2025)"},{"key":"208","unstructured":"208) https:\/\/www.echemi.com\/cms\/1245590.html (Accessed 24 Aug., 2025)"},{"key":"209","unstructured":"209) https:\/\/www.basf.com\/global\/en\/media\/news-releases\/2020\/06\/p-20-168.html (Accessed 25 Aug., 2025)"},{"key":"210","unstructured":"210) PoaCure\/Product Information. https:\/\/www.sdsbio.co.jp\/products\/turf\/23809.html (in Japanese) (Accessed 25 Aug., 2025)"},{"key":"211","doi-asserted-by":"crossref","unstructured":"211) C. Brabham, P. Johnen, J. Hendriks, M. Betz, A. Zimmermann, J. Gollihue, W. Serson, C. Kempinski and M. Barrett: Herbicide symptomology and the mechanism of action of methiozolin. <i>Weed Sci.<\/i> <b>69<\/b>, 18\u201330 (2021).","DOI":"10.1017\/wsc.2020.87"},{"key":"212","unstructured":"212) Cinflubrolin\u2014KingAgroot. https:\/\/www.kingagroot.com\/en\/assets\/pdf\/Cinflubrolin.pdf (Accessed 25 Aug., 2025)"},{"key":"213","doi-asserted-by":"crossref","unstructured":"213) S. Kahlau, F. Schr\u00f6der, J. Freigang, B. Laber, G. Lange, D. Passon, S. Klee\u00dfen, M. Lohse, A. Schulz, P. von Koskull-D\u00f6ring, S. Klie and S. Gill: Aclonifen targets solanesyl diphosphate synthase, representing a novel mode of action for herbicides. <i>Pest Manag. Sci.<\/i> <b>76<\/b>, 3377\u20133388 (2020).","DOI":"10.1002\/ps.5781"},{"key":"214","doi-asserted-by":"crossref","unstructured":"214) I. H. Kang, C. Brabham, J. Lee, L. Wu, Q. Lu, M. Yan, P.-S. Lai, D. F. Rhoades, D. Nesnow, S. Jeffrey, B. McGonigle, S.-I. Kim, J. L. Andreassi, S. O. Pember, S. Gutteridge and R. P. Emptage: Dual mode of action herbicide rimisoxafen targets both phytoene desaturase and solanesyl diphosphate synthase. <i>Pest Manag. Sci.<\/i> <b>81<\/b>, 6330\u20136339 (2025).","DOI":"10.1002\/ps.8972"},{"key":"215","doi-asserted-by":"crossref","unstructured":"215) S. Tresch, J. Schmotz and K. Grossmann: Probing mode of action in plant cell cycle by the herbicide endothall, a protein phosphatase inhibitor. <i>Pestic. Biochem. Physiol.<\/i> <b>99<\/b>, 86\u201395 (2011).","DOI":"10.1016\/j.pestbp.2010.11.004"},{"key":"216","doi-asserted-by":"crossref","unstructured":"216) M. Shino, T. Hamada, Y. Shigematsu, K. Hirase and S. Banba: Action mechanism of bleaching herbicide cyclopyrimorate, a novel homogentisate solanesyltransferase inhibitor. <i>J. Pestic. Sci.<\/i> <b>43<\/b>, 233\u2013239 (2018).","DOI":"10.1584\/jpestics.D18-008"},{"key":"217","doi-asserted-by":"crossref","unstructured":"217) M. Shino, T. Hamada, Y. Shigematsu, K. Hirase, S. Banba, Y. Tsukamoto and J. Kadotani: Discovery and mode of action of cyclopyrimorate: A new paddy rice herbicide. In \u201cRecent Highlights in the Discovery and Optimization of Crop Protection Products,\u201d ed. by P. Maienfisch and S. Mangelinckx, Academic Press, pp. 451\u2013457, 2021.","DOI":"10.1016\/B978-0-12-821035-2.00033-4"},{"key":"218","doi-asserted-by":"crossref","unstructured":"218) R. Sadre, M. Frentzen, M. Saeed and T. Hawkes: Catalytic reactions of the homogentisate prenyl transferase involved in plastoquinone-9 biosynthesis. <i>J. Biol. Chem.<\/i> <b>285<\/b>, 18191\u201318198 (2010).","DOI":"10.1074\/jbc.M110.117929"},{"key":"219","unstructured":"219) Dodhylex\u2122 active\/FMC Corp. https:\/\/www.fmc.com\/en\/dodhylexactive (Accessed 27 Aug., 2025)"},{"key":"220","doi-asserted-by":"crossref","unstructured":"220) I. H. Kang, R. P. Emptage, S. I. Kim and S. Gutteridge: A novel mechanism of herbicide action through disruption of pyrimidine biosynthesis. <i>Proc. Natl. Acad. Sci. U.S.A.<\/i> <b>120<\/b>, e2313197120 (2023).","DOI":"10.1073\/pnas.2313197120"},{"key":"221","unstructured":"221) https:\/\/www.syngenta.com\/media\/media-releases\/2023\/syngenta-and-fmc-commercialize-breakthrough-technology-transforms-grass (Accessed 27 Aug., 2025)"},{"key":"222","unstructured":"222) New pesticides for BCPC\u2019s global database. https:\/\/www.bcpc.org\/latest-news\/new-actives-and-new-fields-for-bcpcs-global-database-2 (Accessed 27 Aug., 2025)"},{"key":"223","unstructured":"223) Ledprona: EPA Greenlights Innovative Biopesticide for Potato Crops. https:\/\/www.useforesight.io\/news\/ledprona-epa-greenlights-innovative-biopesticide-for-potato-crops (Accessed 7 Sep., 2025)"}],"container-title":["Journal of Pesticide Science"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.jstage.jst.go.jp\/article\/jpestics\/51\/1\/51_D25-078\/_pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,3,21]],"date-time":"2026-03-21T03:26:44Z","timestamp":1774063604000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.jstage.jst.go.jp\/article\/jpestics\/51\/1\/51_D25-078\/_article"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2026,2,20]]},"references-count":223,"journal-issue":{"issue":"1","published-print":{"date-parts":[[2026]]}},"URL":"https:\/\/doi.org\/10.1584\/jpestics.d25-078","relation":{},"ISSN":["1348-589X","1349-0923"],"issn-type":[{"value":"1348-589X","type":"print"},{"value":"1349-0923","type":"electronic"}],"subject":[],"published":{"date-parts":[[2026,2,20]]},"article-number":"D25-078"}}