{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,2,7]],"date-time":"2026-02-07T04:08:10Z","timestamp":1770437290989,"version":"3.49.0"},"reference-count":73,"publisher":"Informa UK Limited","issue":"2","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Expert Review of Anti-infective Therapy"],"published-print":{"date-parts":[[2008,4]]},"DOI":"10.1586\/14787210.6.2.241","type":"journal-article","created":{"date-parts":[[2008,4,2]],"date-time":"2008-04-02T07:41:04Z","timestamp":1207122064000},"page":"241-250","source":"Crossref","is-referenced-by-count":0,"title":["Management of Lyme disease"],"prefix":"10.1586","volume":"6","author":[{"given":"Kristin M","family":"Corapi","sequence":"first","affiliation":[{"name":"Royal College of Surgeons in Ireland, 123 St Stephen\u2019s Green, Dublin 2, Ireland."}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Samardeep","family":"Gupta","sequence":"additional","affiliation":[{"name":"Instructor in Medicine, Harvard Medical School, Brigham & Women\u2019s Hospital Division of Rheumatology, Immunology and Allergy, 25 Shattuck Street, Boston, MA 02115, USA."}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Matthew H","family":"Liang","sequence":"additional","affiliation":[{"name":"Professor of Medicine at Harvard Medical School and Professor of Health Policy and Management at the Harvard School of Public Health, Brigham & Women\u2019s Hospital Division of Rheumatology, Immunology and Allergy, 25 Shattuck Street, Boston, MA 02115, USA."}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"301","published-online":{"date-parts":[[2014,1,10]]},"reference":[{"key":"e_1_3_2_3_1","doi-asserted-by":"publisher","DOI":"10.7326\/0003-4819-86-6-685"},{"key":"e_1_3_2_4_1","first-page":"573","volume":"56","year":"2007","unstructured":"US CDC. Lyme disease \u2013 United States, 2003\u20132005. MMWR Morb. Mortal. Wkly Rep.56(23), 573\u2013576 (2007).","journal-title":"MMWR Morb. Mortal. Wkly Rep."},{"key":"e_1_3_2_5_1","first-page":"365","volume":"53","year":"2004","unstructured":"Centers for Disease Control and Prevention (CDC). Lyme disease \u2013 United States, 2001\u20132002. MMWR Morb. Mortal. Wkly Rep.53(17), 365\u2013369 (2004).","journal-title":"MMWR Morb. Mortal. Wkly Rep."},{"key":"e_1_3_2_6_1","doi-asserted-by":"publisher","DOI":"10.4065\/76.7.713"},{"key":"e_1_3_2_7_1","doi-asserted-by":"publisher","DOI":"10.1385\/COMP:31:4:284"},{"key":"e_1_3_2_8_1","first-page":"79","volume":"40","author":"Burgdorfer","year":"1983","unstructured":"Burgdorfer W, Barbour AG, Hayes SF, P\u00e9ter O, Aeschlimann A. Erythema chronicum migrans \u2013 a tick-borne spirochetosis. Acta Trop.40(1), 79\u201383 (1983).","journal-title":"Acta Trop."},{"key":"e_1_3_2_9_1","doi-asserted-by":"publisher","DOI":"10.1007\/s00508-005-0363-6"},{"key":"e_1_3_2_10_1","first-page":"247","volume":"46","author":"Hu","year":"2001","unstructured":"Hu LT, Klempner MS. Update on the prevention, diagnosis, and treatment of Lyme disease. Adv. Intern. Med.46, 247\u2013275 (2001).","journal-title":"Adv. Intern. Med."},{"key":"e_1_3_2_11_1","doi-asserted-by":"publisher","DOI":"10.1007\/s00508-006-0687-x"},{"key":"e_1_3_2_12_1","doi-asserted-by":"publisher","DOI":"10.1016\/S1473-3099(03)00722-9"},{"key":"e_1_3_2_13_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0966-842X(01)02298-3"},{"key":"e_1_3_2_14_1","doi-asserted-by":"publisher","DOI":"10.1017\/S0031182003004694"},{"key":"e_1_3_2_15_1","doi-asserted-by":"publisher","DOI":"10.1056\/NEJMcpc079005"},{"key":"e_1_3_2_16_1","doi-asserted-by":"publisher","DOI":"10.7326\/0003-4819-136-6-200203190-00005"},{"key":"e_1_3_2_17_1","doi-asserted-by":"publisher","DOI":"10.7326\/0003-4819-99-1-76"},{"key":"e_1_3_2_18_1","doi-asserted-by":"publisher","DOI":"10.1179\/joc.2005.17.Supplement-2.3"},{"key":"e_1_3_2_19_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0140-6736(03)14798-8"},{"key":"e_1_3_2_20_1","doi-asserted-by":"publisher","DOI":"10.7326\/0003-4819-142-9-200505030-00011"},{"key":"e_1_3_2_21_1","doi-asserted-by":"publisher","DOI":"10.1016\/S1474-4422(07)70128-X"},{"key":"e_1_3_2_22_1","first-page":"71","volume":"8","author":"Perkins","year":"2006","unstructured":"Perkins MP, Shumway N, Jackson WL. Lyme neuroborreliosis presenting as the syndrome of inappropriate antidiuretic hormone secretion. MedGenMed8(3), 71 (2006).","journal-title":"MedGenMed"},{"key":"e_1_3_2_23_1","doi-asserted-by":"publisher","DOI":"10.1001\/archneur.62.4.671"},{"key":"e_1_3_2_24_1","doi-asserted-by":"publisher","DOI":"10.1586\/14787210.2.1.1"},{"key":"e_1_3_2_25_1","doi-asserted-by":"publisher","DOI":"10.1086\/508667"},{"key":"e_1_3_2_26_1","doi-asserted-by":"publisher","DOI":"10.1586\/14787210.3.2.155"},{"key":"e_1_3_2_27_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.micinf.2006.03.008"},{"key":"e_1_3_2_28_1","doi-asserted-by":"publisher","DOI":"10.1056\/NEJM200111083451913"},{"key":"e_1_3_2_29_1","first-page":"1439","volume":"34","author":"Phillips","year":"2005","unstructured":"Phillips SE, Burrascano JJ, Harris NS, Johnson L, Smith PV, Stricker RB. Chronic infection in \u2018post-Lyme borreliosis syndrome.\u2019 Int. J. Epidemiol.34(6), 1439\u20131440 (2005).","journal-title":"J. Epidemiol."},{"key":"e_1_3_2_30_1","doi-asserted-by":"publisher","DOI":"10.1093\/ije\/dyi129"},{"key":"e_1_3_2_31_1","doi-asserted-by":"publisher","DOI":"10.1093\/ije\/dyi241"},{"key":"e_1_3_2_32_1","doi-asserted-by":"publisher","DOI":"10.1007\/s001340100968"},{"key":"e_1_3_2_33_1","doi-asserted-by":"publisher","DOI":"10.1001\/jama.1988.03720180063034"},{"key":"e_1_3_2_34_1","doi-asserted-by":"publisher","DOI":"10.7326\/0003-4819-103-3-374"},{"key":"e_1_3_2_35_1","first-page":"297","volume":"72","author":"Depietropaolo","year":"2005","unstructured":"Depietropaolo DL, Powers JH, Gill JM. Diagnosis of Lyme disease. Am. Fam. Physician72(2), 297\u2013304 (2005).","journal-title":"Am. Fam. Physician"},{"key":"e_1_3_2_36_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.clindermatol.2006.07.012"},{"key":"e_1_3_2_37_1","doi-asserted-by":"publisher","DOI":"10.1056\/NEJMcp061181"},{"key":"e_1_3_2_38_1","doi-asserted-by":"publisher","DOI":"10.1128\/jcm.35.3.537-543.1997"},{"key":"e_1_3_2_39_1","doi-asserted-by":"publisher","DOI":"10.1128\/CMR.18.3.484-509.2005"},{"key":"e_1_3_2_40_1","doi-asserted-by":"publisher","DOI":"10.2165\/00066982-200106010-00001"},{"key":"e_1_3_2_41_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1574-695X.2006.00139.x"},{"key":"e_1_3_2_42_1","doi-asserted-by":"publisher","DOI":"10.1093\/infdis\/174.3.623"},{"key":"e_1_3_2_43_1","doi-asserted-by":"publisher","DOI":"10.1212\/WNL.42.1.32"},{"key":"e_1_3_2_44_1","doi-asserted-by":"publisher","DOI":"10.1128\/CMR.10.1.185"},{"key":"e_1_3_2_45_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1365-2753.2006.00734.x"},{"key":"e_1_3_2_46_1","doi-asserted-by":"publisher","DOI":"10.1056\/NEJM200107123450201"},{"key":"e_1_3_2_47_1","doi-asserted-by":"publisher","DOI":"10.1016\/S1473-3099(07)70117-2"},{"key":"e_1_3_2_48_1","doi-asserted-by":"publisher","DOI":"10.1136\/ard.2004.027367"},{"key":"e_1_3_2_49_1","doi-asserted-by":"publisher","DOI":"10.1086\/314053"},{"key":"e_1_3_2_50_1","first-page":"41","volume":"46","year":"2005","unstructured":"The Medical Letter. Treatment of Lyme disease. Med. Lett. Drugs Ther.46(1209), 41\u201343 (2005).","journal-title":"Med. Lett. Drugs Ther."},{"key":"e_1_3_2_51_1","doi-asserted-by":"publisher","DOI":"10.7326\/0003-4819-138-9-200305060-00005"},{"key":"e_1_3_2_52_1","doi-asserted-by":"publisher","DOI":"10.1007\/s00508-006-0693-z"},{"key":"e_1_3_2_53_1","doi-asserted-by":"publisher","DOI":"10.1007\/s00508-006-0698-7"},{"key":"e_1_3_2_54_1","doi-asserted-by":"publisher","DOI":"10.1212\/01.wnl.0000265517.66976.28"},{"key":"e_1_3_2_55_1","doi-asserted-by":"publisher","DOI":"10.1007\/s10096-007-0340-2"},{"key":"e_1_3_2_56_1","doi-asserted-by":"publisher","DOI":"10.1002\/art.22131"},{"key":"e_1_3_2_57_1","first-page":"461","volume":"12","author":"Cimmino","year":"1994","unstructured":"Cimmino MA, Sambri V, Massaria F, Accardo S. An in-vitro study of the susceptibility of Borrelia burgdorferi to hydroxychloroquine sulfate. Clin. Exp. Rheumatol.12, 461\u2013462 (1994).","journal-title":"Clin. Exp. Rheumatol."},{"key":"e_1_3_2_58_1","doi-asserted-by":"publisher","DOI":"10.1007\/s10123-002-0055-2"},{"key":"e_1_3_2_59_1","doi-asserted-by":"publisher","DOI":"10.1007\/s00508-005-0361-8"},{"key":"e_1_3_2_60_1","doi-asserted-by":"publisher","DOI":"10.1212\/01.WNL.0000071227.23769.9E"},{"key":"e_1_3_2_61_1","doi-asserted-by":"publisher","DOI":"10.1056\/NEJM200107123450202"},{"key":"e_1_3_2_62_1","doi-asserted-by":"publisher","DOI":"10.1056\/NEJM200111083451913"},{"key":"e_1_3_2_63_1","doi-asserted-by":"publisher","DOI":"10.1056\/NEJMra072023"},{"key":"e_1_3_2_64_1","doi-asserted-by":"publisher","DOI":"10.1586\/14787210.5.5.759"},{"key":"e_1_3_2_65_1","doi-asserted-by":"publisher","DOI":"10.1056\/NEJMra021397"},{"key":"e_1_3_2_66_1","doi-asserted-by":"publisher","DOI":"10.1038\/ncprheum0374"},{"key":"e_1_3_2_67_1","first-page":"1164","volume":"49","author":"Couch","year":"1992","unstructured":"Couch P, Johnson CE. Prevention of Lyme disease. Am. J. Hosp. Pharm.49(5), 1164\u20131173 (1992).","journal-title":"Am. J. Hosp. Pharm."},{"key":"e_1_3_2_68_1","doi-asserted-by":"publisher","DOI":"10.1542\/peds.105.1.142"},{"key":"e_1_3_2_69_1","doi-asserted-by":"publisher","DOI":"10.1177\/1090198106294646"},{"key":"e_1_3_2_70_1","doi-asserted-by":"publisher","DOI":"10.1002\/art.10270"},{"key":"e_1_3_2_71_1","doi-asserted-by":"publisher","DOI":"10.1002\/art.10283"},{"key":"e_1_3_2_72_1","doi-asserted-by":"publisher","DOI":"10.1038\/439524a"},{"key":"e_1_3_2_73_1","first-page":"1","volume":"48","year":"1999","unstructured":"US CDC. Recommendations for the use of Lyme disease vaccine: recommendations of the Advisory Committee on Immunization Practices (ACIP). MMWR Recomm. Rep.48(RR-7), 1\u201317, 21\u201325 (1999).","journal-title":"MMWR Recomm. Rep."},{"key":"e_1_3_2_74_1","doi-asserted-by":"publisher","DOI":"10.1001\/archinte.161.4.554"},{"key":"e_1_3_2_75_2_1","unstructured":"US FDA consumer magazine. Manufacturer discontinues only Lyme disease vaccine www.fda.gov\/fdac\/departs\/2002\/302_upd.html#lyme"}],"container-title":["Expert Review of Anti-infective Therapy"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.tandfonline.com\/doi\/pdf\/10.1586\/14787210.6.2.241","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,2,6]],"date-time":"2026-02-06T13:58:03Z","timestamp":1770386283000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.tandfonline.com\/doi\/full\/10.1586\/14787210.6.2.241"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2008,4]]},"references-count":73,"journal-issue":{"issue":"2","published-print":{"date-parts":[[2008,4]]}},"alternative-id":["10.1586\/14787210.6.2.241"],"URL":"https:\/\/doi.org\/10.1586\/14787210.6.2.241","relation":{},"ISSN":["1478-7210","1744-8336"],"issn-type":[{"value":"1478-7210","type":"print"},{"value":"1744-8336","type":"electronic"}],"subject":[],"published":{"date-parts":[[2008,4]]}}}