{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,29]],"date-time":"2026-09-29T20:40:44Z","timestamp":1790714444526,"version":"4.1.0"},"reference-count":183,"publisher":"Informa UK Limited","issue":"9","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Expert Review of Anti-infective Therapy"],"published-print":{"date-parts":[[2011,9]]},"DOI":"10.1586\/eri.11.96","type":"journal-article","created":{"date-parts":[[2011,9,9]],"date-time":"2011-09-09T17:18:46Z","timestamp":1315588726000},"page":"803-819","source":"Crossref","is-referenced-by-count":60,"title":["Immunopathogenesis of falciparum malaria: implications for adjunctive therapy in the management of severe and cerebral malaria"],"prefix":"10.1586","volume":"9","author":[{"given":"Sarah J","family":"Higgins","sequence":"first","affiliation":[{"name":"Department of Laboratory Medicine and Pathobiology, University of Toronto, Toronto, ON, Canada"},{"name":"McLaughlin-Rotman Centre for Global Health and Division of Infectious Diseases Department of Medicine, University Health Network, University of Toronto, Toronto, ON, Canada"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Kevin C","family":"Kain","sequence":"additional","affiliation":[{"name":"McLaughlin-Rotman Centre for Global Health and Division of Infectious Diseases Department of Medicine, University Health Network, University of Toronto, Toronto, ON, Canada"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"W Conrad","family":"Liles","sequence":"additional","affiliation":[{"name":"McLaughlin-Rotman Centre for Global Health and Division of Infectious Diseases Department of Medicine, University Health Network, University of Toronto, Toronto, ON, Canada"},{"name":"Toronto General Hospital, 200 Elizabeth Street, 13EN-220 Toronto, ON, M4E 3L6 Canada"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"301","published-online":{"date-parts":[[2014,1,10]]},"reference":[{"key":"e_1_3_3_3_1","unstructured":"WHO. World Health Organization: World Malaria Report. World Health Organization Geneva Switzerland (2010)."},{"key":"e_1_3_3_4_1","unstructured":"WHO. World Health Organization: Management of Severe Malaria: A Practical Handbook. (2nd Edition). World Health Organization Geneva Switzerland (2000)."},{"key":"e_1_3_3_5_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0140-6736(10)61924-1"},{"key":"e_1_3_3_6_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0140-6736(05)67176-0"},{"key":"e_1_3_3_7_1","doi-asserted-by":"publisher","DOI":"10.1542\/peds.2007-3709"},{"key":"e_1_3_3_8_1","doi-asserted-by":"publisher","DOI":"10.1203\/PDR.0b013e3181eee738"},{"key":"e_1_3_3_9_1","doi-asserted-by":"publisher","DOI":"10.1186\/1756-0500-3-104"},{"key":"e_1_3_3_10_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0140-6736(08)61655-4"},{"key":"e_1_3_3_11_1","unstructured":"Osler W. The Evolution of Modern Medicine; a Series of Lectures Delivered at Yale University on the Silliman Foundation in April 1913. Yale University Press New Haven CT USA (1921)."},{"key":"e_1_3_3_12_1","doi-asserted-by":"publisher","DOI":"10.1073\/pnas.0908451106"},{"key":"e_1_3_3_13_1","doi-asserted-by":"publisher","DOI":"10.1038\/ni.f.205"},{"key":"e_1_3_3_14_1","doi-asserted-by":"publisher","DOI":"10.1128\/CMR.00025-08"},{"key":"e_1_3_3_15_1","doi-asserted-by":"publisher","DOI":"10.1016\/0140-6736(90)92827-5"},{"key":"e_1_3_3_16_1","doi-asserted-by":"publisher","DOI":"10.1016\/S1473-3099(02)00344-4"},{"key":"e_1_3_3_17_1","doi-asserted-by":"publisher","DOI":"10.1128\/IAI.72.10.5630-5637.2004"},{"key":"e_1_3_3_18_1","doi-asserted-by":"publisher","DOI":"10.1086\/315016"},{"key":"e_1_3_3_19_1","doi-asserted-by":"publisher","DOI":"10.4269\/ajtmh.1999.61.467"},{"key":"e_1_3_3_20_1","doi-asserted-by":"publisher","DOI":"10.1179\/136485905X51508"},{"key":"e_1_3_3_21_1","doi-asserted-by":"publisher","DOI":"10.4269\/ajtmh.2001.64.207"},{"key":"e_1_3_3_22_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.tracli.2008.04.013"},{"key":"e_1_3_3_23_1","doi-asserted-by":"publisher","DOI":"10.1073\/pnas.98.4.1805"},{"key":"e_1_3_3_24_1","doi-asserted-by":"publisher","DOI":"10.1038\/nm986"},{"key":"e_1_3_3_25_1","doi-asserted-by":"publisher","DOI":"10.4269\/ajtmh.2003.69.345"},{"key":"e_1_3_3_26_1","doi-asserted-by":"publisher","DOI":"10.1073\/pnas.80.16.5075"},{"key":"e_1_3_3_27_1","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pone.0014741"},{"key":"e_1_3_3_28_1","doi-asserted-by":"publisher","DOI":"10.4269\/ajtmh.1997.57.389"},{"key":"e_1_3_3_29_1","first-page":"385","volume":"119","author":"MacPherson","year":"1985","unstructured":"MacPherson GG, Warrell MJ, White NJ, Looareesuwan S, Warrell DA. Human cerebral malaria. A quantitative ultrastructural analysis of parasitized erythrocyte sequestration. Am. J. Pathol.119(3), 385\u2013401 (1985).","journal-title":"Am. J. Pathol."},{"key":"e_1_3_3_30_1","first-page":"1057","volume":"145","author":"Turner","year":"1994","unstructured":"Turner GD, Morrison H, Jones M et al. An immunohistochemical study of the pathology of fatal malaria. Evidence for widespread endothelial activation and a potential role for intercellular adhesion molecule-1 in cerebral sequestration. Am. J. Pathol.145(5), 1057\u20131069 (1994).","journal-title":"Am. J. Pathol."},{"key":"e_1_3_3_31_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ajpath.2011.01.016"},{"key":"e_1_3_3_32_1","doi-asserted-by":"publisher","DOI":"10.1182\/blood.V78.3.812.812"},{"key":"e_1_3_3_33_1","doi-asserted-by":"publisher","DOI":"10.1128\/iai.63.6.2323-2326.1995"},{"key":"e_1_3_3_34_1","doi-asserted-by":"publisher","DOI":"10.1016\/0140-6736(90)93174-N"},{"key":"e_1_3_3_35_1","doi-asserted-by":"publisher","DOI":"10.1038\/40888"},{"key":"e_1_3_3_36_1","doi-asserted-by":"publisher","DOI":"10.4269\/ajtmh.2009.09-0406"},{"key":"e_1_3_3_37_1","doi-asserted-by":"publisher","DOI":"10.1038\/nm1351"},{"key":"e_1_3_3_38_1","doi-asserted-by":"publisher","DOI":"10.1371\/journal.ppat.1000349"},{"key":"e_1_3_3_39_1","doi-asserted-by":"publisher","DOI":"10.1182\/blood-2010-09-267492"},{"key":"e_1_3_3_40_1","doi-asserted-by":"publisher","DOI":"10.1182\/blood-2009-07-235150"},{"key":"e_1_3_3_41_1","doi-asserted-by":"publisher","DOI":"10.1080\/10739680701451516"},{"key":"e_1_3_3_42_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.molbiopara.2009.03.006"},{"key":"e_1_3_3_43_1","doi-asserted-by":"publisher","DOI":"10.1038\/nri1686"},{"key":"e_1_3_3_44_1","doi-asserted-by":"publisher","DOI":"10.1182\/blood-2007-04-084582"},{"key":"e_1_3_3_45_1","doi-asserted-by":"publisher","DOI":"10.1086\/595735"},{"key":"e_1_3_3_46_1","doi-asserted-by":"publisher","DOI":"10.1086\/523762"},{"key":"e_1_3_3_47_1","doi-asserted-by":"publisher","DOI":"10.1007\/s10278-010-9323-4"},{"key":"e_1_3_3_48_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.pt.2009.10.007"},{"key":"e_1_3_3_49_1","doi-asserted-by":"publisher","DOI":"10.1017\/S0031182009991715"},{"key":"e_1_3_3_50_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.pt.2010.03.002"},{"key":"e_1_3_3_51_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.pt.2010.03.008"},{"key":"e_1_3_3_52_1","doi-asserted-by":"publisher","DOI":"10.1586\/eri.10.90"},{"key":"e_1_3_3_53_1","doi-asserted-by":"publisher","DOI":"10.1038\/nrneurol.2009.23"},{"key":"e_1_3_3_54_1","doi-asserted-by":"publisher","DOI":"10.1056\/NEJMoa1101549"},{"key":"e_1_3_3_55_1","doi-asserted-by":"publisher","DOI":"10.1056\/NEJMe1105490"},{"key":"e_1_3_3_56_1","doi-asserted-by":"publisher","DOI":"10.1210\/me.2002-0106"},{"key":"e_1_3_3_57_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0960-0760(02)00263-7"},{"key":"e_1_3_3_58_1","doi-asserted-by":"publisher","DOI":"10.1136\/bmj.3.5609.31"},{"key":"e_1_3_3_59_1","doi-asserted-by":"publisher","DOI":"10.1001\/jama.1967.03130210053006"},{"key":"e_1_3_3_60_1","doi-asserted-by":"publisher","DOI":"10.1136\/bmj.3.5618.617-b"},{"key":"e_1_3_3_61_1","doi-asserted-by":"publisher","DOI":"10.1093\/infdis\/158.2.325"},{"key":"e_1_3_3_62_1","doi-asserted-by":"publisher","DOI":"10.1056\/NEJM198202113060601"},{"key":"e_1_3_3_63_1","doi-asserted-by":"publisher","DOI":"10.1136\/bmj.285.6355.1652-c"},{"key":"e_1_3_3_64_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1365-2249.1992.tb05851.x"},{"key":"e_1_3_3_65_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.trstmh.2004.05.005"},{"key":"e_1_3_3_66_1","doi-asserted-by":"publisher","DOI":"10.4269\/ajtmh.1991.45.608"},{"key":"e_1_3_3_67_1","doi-asserted-by":"publisher","DOI":"10.1086\/315078"},{"key":"e_1_3_3_68_1","doi-asserted-by":"publisher","DOI":"10.1126\/science.3306918"},{"key":"e_1_3_3_69_1","doi-asserted-by":"publisher","DOI":"10.1093\/infdis\/174.5.1091"},{"key":"e_1_3_3_70_1","doi-asserted-by":"publisher","DOI":"10.1182\/blood.V79.12.3362.bloodjournal79123362"},{"key":"e_1_3_3_71_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0171-2985(11)80356-6"},{"key":"e_1_3_3_72_1","doi-asserted-by":"publisher","DOI":"10.4269\/ajtmh.1998.58.343"},{"key":"e_1_3_3_73_1","doi-asserted-by":"publisher","DOI":"10.1046\/j.1365-3156.2003.01087.x"},{"key":"e_1_3_3_74_1","doi-asserted-by":"publisher","DOI":"10.1093\/infdis\/171.5.1317"},{"key":"e_1_3_3_75_1","doi-asserted-by":"publisher","DOI":"10.4269\/ajtmh.1998.58.348"},{"key":"e_1_3_3_76_1","doi-asserted-by":"publisher","DOI":"10.1186\/1475-2875-9-368"},{"key":"e_1_3_3_77_1","doi-asserted-by":"publisher","DOI":"10.4269\/ajtmh.1997.56.397"},{"key":"e_1_3_3_78_1","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pone.0009867"},{"key":"e_1_3_3_79_1","doi-asserted-by":"publisher","DOI":"10.1084\/jem.20020128"},{"key":"e_1_3_3_80_1","doi-asserted-by":"publisher","DOI":"10.1086\/597258"},{"key":"e_1_3_3_81_1","doi-asserted-by":"publisher","DOI":"10.1056\/NEJM199505253322102"},{"key":"e_1_3_3_82_1","first-page":"441","volume":"71","author":"Molyneux","year":"1989","unstructured":"Molyneux ME, Taylor TE, Wirima JJ, Borgstein A. Clinical features and prognostic indicators in paediatric cerebral malaria: a study of 131 comatose Malawian children. Q. J. Med.71(265), 441\u2013459 (1989).","journal-title":"Q. J. Med."},{"key":"e_1_3_3_83_1","doi-asserted-by":"publisher","DOI":"10.1086\/649928"},{"key":"e_1_3_3_84_1","doi-asserted-by":"publisher","DOI":"10.1086\/648409"},{"key":"e_1_3_3_85_1","doi-asserted-by":"publisher","DOI":"10.4269\/ajtmh.2006.75.790"},{"key":"e_1_3_3_86_1","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pone.0004317"},{"key":"e_1_3_3_87_1","doi-asserted-by":"publisher","DOI":"10.1038\/nrclinonc.2010.43"},{"key":"e_1_3_3_88_1","doi-asserted-by":"publisher","DOI":"10.1586\/eri.10.154"},{"key":"e_1_3_3_89_1","doi-asserted-by":"publisher","DOI":"10.1097\/CCM.0b013e3181a02afc"},{"key":"e_1_3_3_90_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.addr.2009.11.016"},{"key":"e_1_3_3_91_1","doi-asserted-by":"publisher","DOI":"10.1056\/NEJM198906153202404"},{"key":"e_1_3_3_92_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0002-9343(89)80688-6"},{"key":"e_1_3_3_93_1","first-page":"113","volume":"11","author":"Akanmori","year":"2000","unstructured":"Akanmori BD, Kurtzhals JA, Goka BQ et al. Distinct patterns of cytokine regulation in discrete clinical forms of Plasmodium falciparum malaria. Eur. Cytokine. Netw.11(1), 113\u2013118 (2000).","journal-title":"Eur. Cytokine. Netw."},{"key":"e_1_3_3_94_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.actatropica.2007.02.011"},{"key":"e_1_3_3_95_1","doi-asserted-by":"publisher","DOI":"10.1073\/pnas.0805782105"},{"key":"e_1_3_3_96_1","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pone.0017440"},{"key":"e_1_3_3_97_1","first-page":"665","volume":"83","author":"Jakobsen","year":"1994","unstructured":"Jakobsen PH, Morris-Jones S, Ronn A et al. Increased plasma concentrations of sICAM-1, sVCAM-1 and sELAM-1 in patients with Plasmodium falciparum or P. vivax malaria and association with disease severity. Immunology83(4), 665\u2013669 (1994).","journal-title":"Immunology"},{"key":"e_1_3_3_98_1","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pone.0015291"},{"key":"e_1_3_3_99_1","doi-asserted-by":"publisher","DOI":"10.1038\/nri2532"},{"key":"e_1_3_3_100_1","doi-asserted-by":"publisher","DOI":"10.1038\/nri2171"},{"key":"e_1_3_3_101_1","doi-asserted-by":"publisher","DOI":"10.1056\/NEJM199312303292706"},{"key":"e_1_3_3_102_1","doi-asserted-by":"publisher","DOI":"10.1172\/JCI118074"},{"key":"e_1_3_3_103_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0002-9440(10)64299-X"},{"key":"e_1_3_3_104_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0092-8674(03)00803-1"},{"key":"e_1_3_3_105_1","doi-asserted-by":"publisher","DOI":"10.1084\/jem.184.2.557"},{"key":"e_1_3_3_106_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0140-6736(03)12564-0"},{"key":"e_1_3_3_107_1","doi-asserted-by":"publisher","DOI":"10.1084\/jem.20070819"},{"key":"e_1_3_3_108_1","doi-asserted-by":"publisher","DOI":"10.1371\/journal.ppat.1000868"},{"key":"e_1_3_3_109_1","doi-asserted-by":"publisher","DOI":"10.1086\/644641"},{"key":"e_1_3_3_110_1","first-page":"1717","volume":"55","author":"DiBlasi","year":"2010","unstructured":"DiBlasi RM, Myers TR, Hess DR. Evidence-based clinical practice guideline: inhaled nitric oxide for neonates with acute hypoxic respiratory failure. Respir. Care55(12), 1717\u20131745 (2010).","journal-title":"Respir. Care"},{"key":"e_1_3_3_111_1","doi-asserted-by":"publisher","DOI":"10.1038\/nm1499"},{"key":"e_1_3_3_112_1","doi-asserted-by":"publisher","DOI":"10.1093\/infdis\/jir058"},{"key":"e_1_3_3_113_1","doi-asserted-by":"publisher","DOI":"10.1086\/590209"},{"key":"e_1_3_3_114_1","doi-asserted-by":"publisher","DOI":"10.1097\/MOH.0b013e328345a4cf"},{"key":"e_1_3_3_115_1","doi-asserted-by":"publisher","DOI":"10.1055\/s-0037-1615677"},{"key":"e_1_3_3_116_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0092-8674(00)81813-9"},{"key":"e_1_3_3_117_1","doi-asserted-by":"publisher","DOI":"10.1128\/mcb.12.4.1698-1707.1992"},{"key":"e_1_3_3_118_1","doi-asserted-by":"publisher","DOI":"10.1038\/ncb1714"},{"key":"e_1_3_3_119_1","doi-asserted-by":"publisher","DOI":"10.1038\/ncb1715"},{"key":"e_1_3_3_120_1","doi-asserted-by":"publisher","DOI":"10.1161\/hh1801.097034"},{"key":"e_1_3_3_121_1","doi-asserted-by":"publisher","DOI":"10.1007\/s00436-001-0518-y"},{"key":"e_1_3_3_122_1","doi-asserted-by":"publisher","DOI":"10.1182\/blood-2003-10-3685"},{"key":"e_1_3_3_123_1","doi-asserted-by":"publisher","DOI":"10.1126\/science.277.5322.55"},{"key":"e_1_3_3_124_1","doi-asserted-by":"publisher","DOI":"10.1161\/CIRCRESAHA.106.143594"},{"key":"e_1_3_3_125_1","doi-asserted-by":"publisher","DOI":"10.1186\/1475-2875-8-295"},{"key":"e_1_3_3_126_1","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pone.0004912"},{"key":"e_1_3_3_127_1","doi-asserted-by":"publisher","DOI":"10.1038\/ki.2009.387"},{"key":"e_1_3_3_128_1","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pmed.0040269"},{"key":"e_1_3_3_129_1","doi-asserted-by":"publisher","DOI":"10.1038\/74725"},{"key":"e_1_3_3_130_1","doi-asserted-by":"publisher","DOI":"10.2353\/ajpath.2009.090391"},{"key":"e_1_3_3_131_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ccr.2004.09.030"},{"key":"e_1_3_3_132_1","doi-asserted-by":"publisher","DOI":"10.1517\/14728220802626256"},{"key":"e_1_3_3_133_1","doi-asserted-by":"publisher","DOI":"10.1084\/jem.20080406"},{"key":"e_1_3_3_134_1","doi-asserted-by":"publisher","DOI":"10.1161\/01.CIR.0000055324.34758.32"},{"key":"e_1_3_3_135_1","doi-asserted-by":"publisher","DOI":"10.1182\/blood-2004-04-1519"},{"key":"e_1_3_3_136_1","doi-asserted-by":"publisher","DOI":"10.1074\/jbc.274.22.15732"},{"key":"e_1_3_3_137_1","doi-asserted-by":"publisher","DOI":"10.1161\/ATVBAHA.107.150482"},{"key":"e_1_3_3_138_1","doi-asserted-by":"publisher","DOI":"10.1074\/jbc.M009705200"},{"key":"e_1_3_3_139_1","doi-asserted-by":"publisher","DOI":"10.1073\/pnas.0709715105"},{"key":"e_1_3_3_140_1","doi-asserted-by":"publisher","DOI":"10.1371\/journal.ppat.1000916"},{"key":"e_1_3_3_141_1","doi-asserted-by":"publisher","DOI":"10.1186\/1475-2875-7-83"},{"key":"e_1_3_3_142_1","doi-asserted-by":"publisher","DOI":"10.1007\/s10096-010-1122-9"},{"key":"e_1_3_3_143_1","doi-asserted-by":"publisher","DOI":"10.1126\/science.294.5548.1866"},{"key":"e_1_3_3_144_1","doi-asserted-by":"publisher","DOI":"10.1146\/annurev.med.53.082901.104018"},{"key":"e_1_3_3_145_1","doi-asserted-by":"publisher","DOI":"10.1007\/s000110050622"},{"key":"e_1_3_3_146_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.bbalip.2007.04.021"},{"key":"e_1_3_3_147_1","doi-asserted-by":"publisher","DOI":"10.4049\/jimmunol.180.3.1854"},{"key":"e_1_3_3_148_1","doi-asserted-by":"publisher","DOI":"10.1096\/fj.08-121624"},{"key":"e_1_3_3_149_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.phrs.2010.03.002"},{"key":"e_1_3_3_150_1","doi-asserted-by":"publisher","DOI":"10.1161\/01.ATV.0000044461.01844.C9"},{"key":"e_1_3_3_151_1","doi-asserted-by":"publisher","DOI":"10.1161\/01.HYP.0000103629.01745.59"},{"key":"e_1_3_3_152_1","doi-asserted-by":"publisher","DOI":"10.1074\/jbc.M710048200"},{"key":"e_1_3_3_153_1","doi-asserted-by":"publisher","DOI":"10.3233\/CH-2010-1315"},{"key":"e_1_3_3_154_1","doi-asserted-by":"publisher","DOI":"10.1086\/598222"},{"key":"e_1_3_3_155_1","doi-asserted-by":"publisher","DOI":"10.1086\/605431"},{"key":"e_1_3_3_156_1","doi-asserted-by":"publisher","DOI":"10.1086\/605432"},{"key":"e_1_3_3_157_1","doi-asserted-by":"publisher","DOI":"10.1056\/NEJMoa072761"},{"key":"e_1_3_3_158_1","doi-asserted-by":"publisher","DOI":"10.1073\/pnas.0406491101"},{"key":"e_1_3_3_159_1","doi-asserted-by":"publisher","DOI":"10.1046\/j.1460-9568.2003.02987.x"},{"key":"e_1_3_3_160_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.brainres.2007.08.078"},{"key":"e_1_3_3_161_1","doi-asserted-by":"publisher","DOI":"10.1084\/jem.20021067"},{"key":"e_1_3_3_162_1","doi-asserted-by":"publisher","DOI":"10.1073\/pnas.97.19.10526"},{"key":"e_1_3_3_163_1","doi-asserted-by":"publisher","DOI":"10.1073\/pnas.95.8.4635"},{"key":"e_1_3_3_164_1","doi-asserted-by":"publisher","DOI":"10.1186\/1475-2875-8-261"},{"key":"e_1_3_3_165_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.actatropica.2008.02.001"},{"key":"e_1_3_3_166_1","doi-asserted-by":"publisher","DOI":"10.1186\/1475-2875-7-3"},{"key":"e_1_3_3_167_1","doi-asserted-by":"publisher","DOI":"10.1086\/500844"},{"key":"e_1_3_3_168_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ejphar.2011.01.043"},{"key":"e_1_3_3_169_1","doi-asserted-by":"publisher","DOI":"10.1161\/STROKEAHA.109.564872"},{"key":"e_1_3_3_170_1","doi-asserted-by":"publisher","DOI":"10.1016\/S1470-2045(03)01163-X"},{"key":"e_1_3_3_171_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.nurt.2008.10.041"},{"key":"e_1_3_3_172_1","doi-asserted-by":"publisher","DOI":"10.1038\/sj.cdd.4401450"},{"key":"e_1_3_3_173_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1462-5822.2010.01528.x"},{"key":"e_1_3_3_174_1","doi-asserted-by":"publisher","DOI":"10.1086\/519287"},{"key":"e_1_3_3_175_1","doi-asserted-by":"publisher","DOI":"10.1182\/blood.V96.9.3231"},{"key":"e_1_3_3_176_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.pt.2003.08.006"},{"key":"e_1_3_3_177_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1365-3156.2009.02298.x"},{"key":"e_1_3_3_178_1","doi-asserted-by":"publisher","DOI":"10.1038\/71582"},{"key":"e_1_3_3_179_1","doi-asserted-by":"publisher","DOI":"10.4269\/ajtmh.1992.46.595"},{"key":"e_1_3_3_180_1","doi-asserted-by":"publisher","DOI":"10.4269\/ajtmh.1994.51.198"},{"key":"e_1_3_3_181_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0035-9203(98)90969-5"},{"key":"e_1_3_3_182_1","doi-asserted-by":"publisher","DOI":"10.1073\/pnas.1018692108"},{"key":"e_1_3_3_183_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0163-7258(98)00008-4"},{"key":"e_1_3_3_184_1","doi-asserted-by":"publisher","DOI":"10.1128\/AAC.00421-08"},{"key":"e_1_3_3_185_1","doi-asserted-by":"publisher","DOI":"10.1186\/1475-2875-8-169"}],"container-title":["Expert Review of Anti-infective Therapy"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.tandfonline.com\/doi\/pdf\/10.1586\/eri.11.96","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,2,6]],"date-time":"2026-02-06T18:00:41Z","timestamp":1770400841000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.tandfonline.com\/doi\/full\/10.1586\/eri.11.96"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2011,9]]},"references-count":183,"journal-issue":{"issue":"9","published-print":{"date-parts":[[2011,9]]}},"alternative-id":["10.1586\/eri.11.96"],"URL":"https:\/\/doi.org\/10.1586\/eri.11.96","relation":{},"ISSN":["1478-7210","1744-8336"],"issn-type":[{"value":"1478-7210","type":"print"},{"value":"1744-8336","type":"electronic"}],"subject":[],"published":{"date-parts":[[2011,9]]}}}