{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,10]],"date-time":"2026-10-10T02:46:00Z","timestamp":1791600360612,"version":"4.3.4"},"reference-count":22,"publisher":"FapUNIFESP (SciELO)","issue":"1","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["An. Acad. Bras. Ci\u00eanc."],"abstract":"<jats:p>Background: There is no consensus regarding the blood volume that could be safely donated by dogs, ranging from 11 to 25% of its total blood volume (TBV). No previous studies evaluated sedated donors.Aim: To evaluate the hemodynamic effects of blood collection from sedated and non-sedated dogs and to understand if such effects were volume-dependent.Materials and Methods: Fifty three donations of 13% of TBV and 20 donations of 15% TBV were performed in dogs sedated with diazepam and ketamine. Additionally, a total of 30 collections of 13% TBV and 20 collections of 15% TBV were performed in non-sedated dogs. Non-invasive arterial blood pressures and pulse rates were registered before and 15 min after donation. Results: Post-donation pulse rates increased significantly in both sedated groups, with higher differences in the 15% TBV collections. Systolic arterial pressures decreased significantly in these groups, while diastolic pressures increased significantly in 13% TBV donations. Non-sedated groups revealed a slight, but significant, SBP decrease. No clinical signs related to donations were registered.Conclusion: These results suggest that the collection of 15% TBV in sedated donors induces hemodynamic variations that may compromise the harmlessness of the procedure, while it seems to be a safe procedure in non-sedated dogs.<\/jats:p>","DOI":"10.1590\/0001-3765201520140210","type":"journal-article","created":{"date-parts":[[2015,2,2]],"date-time":"2015-02-02T15:44:26Z","timestamp":1422891866000},"page":"381-388","source":"Crossref","is-referenced-by-count":12,"title":["Volume-dependent hemodynamic effects of blood collection in canine donors - evaluation of 13% and 15% of total blood volume depletion"],"prefix":"10.1590","volume":"87","author":[{"given":"RUI R.F.","family":"FERREIRA","sequence":"first","affiliation":[{"name":"Universidade do Porto,  Portugal"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"RAFAEL R.","family":"GOPEGUI","sequence":"additional","affiliation":[{"name":"Universidade Aut\u00f3noma de Barcelona,  Spain"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"AUGUSTO J.F. DE","family":"MATOS","sequence":"additional","affiliation":[{"name":"Instituto de Ci\u00eancias Biom\u00e9dicas Abel Salazar,  Portugal"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"530","published-online":{"date-parts":[[2015,2,3]]},"reference":[{"key":"ref1","doi-asserted-by":"crossref","first-page":"171","DOI":"10.1016\/B978-0-12-039236-0.50011-4","article-title":"Preparation of components","volume":"36","author":"AUTHEMENT JM","year":"1991","journal-title":"Adv Vet Sci Comp Med"},{"key":"ref2","series-title":"Guide to the preparation, use and quality assurance of blood components","first-page":"59","volume-title":"Principles of Component Preparation","year":"2011","edition":"16th"},{"key":"ref3","doi-asserted-by":"crossref","first-page":"845","DOI":"10.1111\/j.1939-1676.2005.tb02775.x","article-title":"Effects of blood donation on arterial blood pressure in retired racing Greyhounds","volume":"19","author":"COUTO CG","year":"2005","journal-title":"J Vet Intern 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