{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,5,15]],"date-time":"2026-05-15T02:07:47Z","timestamp":1778810867125,"version":"3.51.4"},"reference-count":77,"publisher":"FapUNIFESP (SciELO)","issue":"2","license":[{"start":{"date-parts":[[2019,1,1]],"date-time":"2019-01-01T00:00:00Z","timestamp":1546300800000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"},{"start":{"date-parts":[[2019,1,1]],"date-time":"2019-01-01T00:00:00Z","timestamp":1546300800000},"content-version":"am","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"},{"start":{"date-parts":[[2019,1,1]],"date-time":"2019-01-01T00:00:00Z","timestamp":1546300800000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["An. Acad. Bras. Ci\u00eanc."],"DOI":"10.1590\/0001-3765201920180248","type":"journal-article","created":{"date-parts":[[2019,7,2]],"date-time":"2019-07-02T17:13:04Z","timestamp":1562087584000},"source":"Crossref","is-referenced-by-count":7,"title":["Jabuticaba (Plinia jaboticaba) skin extracts as inhibitors of phospholipases A2 and proteases"],"prefix":"10.1590","volume":"91","author":[{"given":"TAMARA R.","family":"MARQUES","sequence":"first","affiliation":[{"name":"Universidade Federal de Lavras\/UFLA, Brazil"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"MARIANA A.","family":"BRAGA","sequence":"additional","affiliation":[{"name":"Universidade Federal de Lavras\/UFLA, Brazil"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"PEDRO H.S.","family":"CESAR","sequence":"additional","affiliation":[{"name":"Universidade Federal de Lavras\/UFLA, Brazil"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-4674-6911","authenticated-orcid":false,"given":"SILVANA","family":"MARCUSSI","sequence":"additional","affiliation":[{"name":"Universidade Federal de Lavras\/UFLA, Brazil"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"ANGELITA D.","family":"CORR\u00caA","sequence":"additional","affiliation":[{"name":"Universidade Federal de Lavras\/UFLA, Brazil"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"530","published-online":{"date-parts":[[2019]]},"reference":[{"key":"ref1","doi-asserted-by":"crossref","first-page":"1679","DOI":"10.1002\/jsfa.5531","article-title":"Potential dietary sources of ellagic acid and other antioxidants among fruits consumed in Brazil: jabuticaba (Myrciaria jaboticaba (Vell","volume":"92","author":"ABE LT","year":"2012","journal-title":"J Sci Food Agric"},{"key":"ref2","first-page":"526","article-title":"Lp-PLA2 et sPLA2 Biomarqueurs cardiovasculaires","volume":"30","author":"AIT-OUFELLA H","year":"2014","journal-title":"Med Sciences"},{"key":"ref3","doi-asserted-by":"crossref","first-page":"721","DOI":"10.4025\/actascitechnol.v36i4.19305","article-title":"Influence of drying temperature on the chemical constituents of jaboticaba (Plinia Jaboticaba (Vell","volume":"36","author":"ALVES APC","year":"2014","journal-title":"Acta Sci Technol"},{"key":"ref4","first-page":"2007","article-title":"Flour and anthocyanin extracts of jaboticaba skins used as a natural dye in yogurt","volume":"48","author":"ALVES APC","year":"2013","journal-title":"IJFST"},{"key":"ref5","doi-asserted-by":"crossref","first-page":"232","DOI":"10.1590\/1678-457x.19016","article-title":"Elaboration and acceptability of restructured hams added with jabuticaba skin","volume":"37","author":"ALVES APC","year":"2017","journal-title":"Food Sci Technol"},{"key":"ref6","series-title":"Official methods of analysis, 19 ed","year":"2016"},{"key":"ref7","doi-asserted-by":"crossref","first-page":"897","DOI":"10.1590\/S0101-20612006000400029","article-title":"Caracteriza\u00e7\u00e3o da farinha de baga\u00e7o de jabuticaba e propriedades funcionais dos extrusados","volume":"26","author":"ASCHERI DPR","year":"2006","journal-title":"Food Sci Technol"},{"key":"ref8","doi-asserted-by":"crossref","first-page":"319","DOI":"10.1080\/10408398.2011.653734","article-title":"Therapeutic and nutraceutical potential of bioactive compounds extracted from fruit residues","volume":"55","author":"BABBAR N","year":"2015","journal-title":"J Crit Rev Food Sci Nutr"},{"key":"ref9","doi-asserted-by":"crossref","first-page":"450","DOI":"10.1016\/j.jff.2013.11.011","article-title":"Intake of jaboticaba peel attenuates oxidative stress in tissues and reduces circulating saturated lipids of rats with high-fat diet-induced obesity","volume":"6","author":"BATISTA \u00c2G","year":"2014","journal-title":"J Funct Foods"},{"key":"ref10","doi-asserted-by":"crossref","DOI":"10.1017\/S0029665116000938","article-title":"Four-weeks intervention with jaboticaba peel lowers MDA levels after post-prandial challenge in healthy adults","volume":"75","author":"BATISTA \u00c2G","year":"2016","journal-title":"Proc Nut Soc"},{"key":"ref11","doi-asserted-by":"crossref","first-page":"2613","DOI":"10.1021\/cr990139w","article-title":"Interfacial enzymology: the secreted phospholipase A2-Paradigm","volume":"101","author":"BERG OG","year":"2001","journal-title":"Chem Rev"},{"key":"ref12","doi-asserted-by":"crossref","first-page":"811","DOI":"10.1016\/j.fitote.2011.04.017","article-title":"Anticoagulant effect of polyphenols-rich extracts from black chokeberry and grape seeds","volume":"82","author":"BIJAK M","year":"2011","journal-title":"Fitoterapia"},{"key":"ref13","doi-asserted-by":"crossref","first-page":"851","DOI":"10.1016\/S0300-9084(00)01178-0","article-title":"Snake venom proteins acting on hemostasis","volume":"82","author":"BRAUD SB","year":"2000","journal-title":"Biochimie"},{"key":"ref14","doi-asserted-by":"crossref","first-page":"1265","DOI":"10.1160\/TH17-02-0079","article-title":"Coagulation factor and protease pathways in thrombosis and cardiovascular disease","volume":"117","author":"CATE HT","year":"2017","journal-title":"J Thromb Haemost"},{"key":"ref15","first-page":"53","article-title":"Phospholipases: at the crossroads of the immune system and the pathogenesis of HIV-1 infection","volume":"101","author":"CECHETTI S","year":"2017","journal-title":"JLB"},{"key":"ref16","doi-asserted-by":"crossref","first-page":"70","DOI":"10.1016\/j.toxicon.2012.03.018","article-title":"Batroxase, a new metalloproteinase from Bothrops atrox snake venom with strong fibrinolytic activity","volume":"60","author":"CINTRA ACO","year":"2012","journal-title":"Toxicon"},{"key":"ref17","doi-asserted-by":"crossref","first-page":"343","DOI":"10.1590\/S0100-29452010000200001","article-title":"Jabuticabeiras","volume":"32","author":"CITADIN I","year":"2010","journal-title":"Rev Bras Frutic"},{"issue":"Suppl 1","key":"ref18","doi-asserted-by":"crossref","first-page":"95","DOI":"10.1111\/j.1538-7836.2007.02500.x","article-title":"The central role of thrombin in hemostasis","volume":"5","author":"CRAWLEY JT","year":"2007","journal-title":"J Thromb Haemost"},{"key":"ref19","doi-asserted-by":"crossref","first-page":"7313","DOI":"10.3390\/molecules15107313","article-title":"Plant phenolics: extraction, analysis and their antioxidant and anticancer properties","volume":"15","author":"DAI J","year":"2010","journal-title":"Molecules"},{"key":"ref20","first-page":"134","article-title":"Screening of thrombolytic activity os Bougainvillea glabra leaves extracts by in-vitro","volume":"2","author":"ELUMALAI A","year":"2012","journal-title":"Asian J Res Pharm Sci"},{"key":"ref21","doi-asserted-by":"crossref","DOI":"10.3390\/nu8030150","article-title":"Clinical evaluation of effects of chronic resveratrol supplementation on cerebrovascular function, cognition, mood, physical function and general well-being in postmenopausal women-rationale and study design","volume":"8","author":"EVANS HM","year":"2016","journal-title":"Nutrients"},{"key":"ref22","doi-asserted-by":"crossref","first-page":"974","DOI":"10.3923\/ajft.2011.974.984","article-title":"Assessment of a maturity index in jabuticaba fruit by the evaluation of phenolic compounds, essential oil components, sugar content and total acidity","volume":"6","author":"FORTES GAC","year":"2011","journal-title":"American J Food Technol"},{"key":"ref23","doi-asserted-by":"crossref","first-page":"1655","DOI":"10.1016\/S1734-1140(13)71527-5","article-title":"Cytokines, prostaglandins and nitric oxide in the regulation of stress-response systems","volume":"65","author":"G\u0104DEK-MICHALSKA A","year":"2013","journal-title":"Pharmacol Rep"},{"key":"ref24","doi-asserted-by":"crossref","first-page":"64","DOI":"10.1016\/j.toxicon.2010.02.031","article-title":"Isolation and functional characterization of a new acidic PLA2 Ba SpII RP4 of the Bothrops alternatus snake venom from Argentina","volume":"56","author":"GARCIA DENEGRI ME","year":"2010","journal-title":"Toxicon"},{"key":"ref25","doi-asserted-by":"crossref","first-page":"411","DOI":"10.1016\/0041-0101(88)90010-4","article-title":"An alternative in vitro method for testing the potency of the polyvalent antivenom produced in Costa Rica","volume":"26","author":"GUTI\u00c9RREZ JM","year":"1988","journal-title":"Toxicon"},{"key":"ref26","doi-asserted-by":"crossref","first-page":"27","DOI":"10.1016\/j.toxicon.2012.09.006","article-title":"Phospholipases A2: unveiling the secrets of a functionally versatile group of snake venom toxins","volume":"2","author":"GUTI\u00c9RREZ JM","year":"2013","journal-title":"Toxicon"},{"key":"ref27","doi-asserted-by":"crossref","first-page":"163","DOI":"10.1016\/0003-2697(72)90495-2","article-title":"A sensitive and specific plate test for the quantitation of phospholipases","volume":"50","author":"HABERMANN E","year":"1972","journal-title":"Anal Biochem"},{"key":"ref28","doi-asserted-by":"crossref","first-page":"323","DOI":"10.1016\/S0896-6273(04)00003-0","article-title":"Cytosolic phospholipase A2 plays a key role in the pathogenesis of multiple sclerosis-like disease","volume":"41","author":"KALYVAS A","year":"2004","journal-title":"Neuron"},{"key":"ref29","doi-asserted-by":"crossref","first-page":"213","DOI":"10.4103\/0974-8490.182916","article-title":"Inhibition of group IIA secretory phospholipase A2 and its inflammatory reactions in mice by ethanolic extract of Andrographis paniculata, a well-known medicinal food","volume":"8","author":"KISHORE V","year":"2016","journal-title":"Pharmacognosy Res"},{"key":"ref30","doi-asserted-by":"crossref","first-page":"7523","DOI":"10.1021\/jm500192s","article-title":"Inhibition of group IVA cytosolic phospholipase A2 by thiazolyl ketones in vitro, ex vivo, and in vivo","volume":"57","author":"KOKOTOS G","year":"2014","journal-title":"J Med Chem"},{"key":"ref31","first-page":"70","article-title":"Antioxidant and anti-inflammatory activities of peels, pulps and seed kernels of three common mango (Mangifera indical L","volume":"8","author":"KUGANESAN G","year":"2017","journal-title":"IJPSR"},{"key":"ref32","doi-asserted-by":"crossref","first-page":"211","DOI":"10.46370\/sajfte.2015.v01i03and04.02","article-title":"Role of edible mushrooms as functional foods - a review","volume":"1","author":"KUMAR K","year":"2015","journal-title":"South Asian J Food Technol Environment"},{"key":"ref33","doi-asserted-by":"crossref","first-page":"116","DOI":"10.46370\/sajfte.2015.v01i02.02","article-title":"Role of nutraceuticals in health and disease prevention: a review","volume":"1","author":"KUMAR K","year":"2015","journal-title":"South Asian J Food Technol Environment"},{"key":"ref34","first-page":"1295","article-title":"Jabuticaba [Pliniajaboticaba (Vell","volume":"13","author":"LAGE FF","year":"2014","journal-title":"African J Biotechnol"},{"key":"ref35","doi-asserted-by":"crossref","first-page":"613","DOI":"10.1007\/s11064-009-0106-6","article-title":"Brain arachidonic acid cascade enzymes are upregulated in a rat model of unilateral Parkinson disease","volume":"35","author":"LEE HJ","year":"2010","journal-title":"Neurochem Res"},{"key":"ref36","doi-asserted-by":"crossref","first-page":"162","DOI":"10.1016\/j.foodres.2015.07.023","article-title":"Jaboticaba peel and jaboticaba peel aqueous extract shows in vitro and in vivo antioxidant properties in obesity model","volume":"77","author":"LENQUISTE SA","year":"2015","journal-title":"Food Res Int"},{"key":"ref37","article-title":"Pharmacology of ginsenosides: a literature review","volume":"5","author":"LEUNG KW","year":"2010","journal-title":"American J Chin Med"},{"key":"ref38","doi-asserted-by":"crossref","first-page":"11","DOI":"10.1111\/j.1476-4431.2009.00383.x","article-title":"Thrombin physiology and pathophysiology","volume":"19","author":"LICARI LG","year":"2009","journal-title":"J Vet Emerg Crit Care"},{"key":"ref39","first-page":"556","article-title":"Interactions of polyphenols with carbohydrates, lipids and proteins","volume":"15","author":"LIDIJA J","year":"2015","journal-title":"Food Chem"},{"key":"ref40","first-page":"416","article-title":"Caracteriza\u00e7\u00e3o qu\u00edmica da fruta jabuticaba (M. cauliflora Berg) e de suas fra\u00e7\u00f5es","volume":"58","author":"LIMA AJB","year":"2008","journal-title":"Arch Latinoam Nutr"},{"key":"ref41","doi-asserted-by":"crossref","first-page":"1226","DOI":"10.1111\/bph.13627","article-title":"Effects of anthocyanins on the prevention and treatment of cancer","volume":"174","author":"LIN BW","year":"2017","journal-title":"Br J Pharmacol"},{"key":"ref42","doi-asserted-by":"crossref","first-page":"50","DOI":"10.1016\/j.biochi.2014.04.002","article-title":"Characterization, mechanism of anticoagulant action and asessment of therapeutic potential of a fibrinolytic serine protease (Brevithrombolase) purified from Brevibacillus brevis strain FF02B","volume":"103","author":"MAJUMDAR S","year":"2014","journal-title":"Biochimie"},{"issue":"1 Suppl","key":"ref43","doi-asserted-by":"crossref","first-page":"230S","DOI":"10.1093\/ajcn\/81.1.230S","article-title":"Bioavailability and bioefficacy of polyphenols in humans","volume":"81","author":"MANACH C","year":"2005","journal-title":"Am J Clin Nutr"},{"key":"ref44","doi-asserted-by":"crossref","first-page":"191","DOI":"10.1016\/j.bjp.2015.08.015","article-title":"Metanolic extract of Malpighia emarginata bagasse: phenolic compounds and inhibitory potential on digestive enzymes","volume":"26","author":"MARQUES TR","year":"2016","journal-title":"Rev Bras Farmacogn"},{"key":"ref45","doi-asserted-by":"crossref","first-page":"655","DOI":"10.1111\/j.1742-4658.2004.04489.x","article-title":"Various secretory phospholipase A2 enzymes are expressed in rheumatoid arthritis and augment prostaglandin production in cultured synovial cells","volume":"272","author":"MASUDA S","year":"2005","journal-title":"FEBS Journal"},{"key":"ref46","series-title":"Introdu\u00e7\u00e3o \u00e0 fitoqu\u00edmica experimental","author":"MATOS FJA","year":"1997"},{"key":"ref47","doi-asserted-by":"crossref","first-page":"136","DOI":"10.1016\/j.jep.2016.02.047","article-title":"The inhibitory potential of the condensed-tannin-rich fraction of Plathymenia reticulata Benth","volume":"13","author":"MOURA VM","year":"2016","journal-title":"J Ethnopharmacology"},{"key":"ref48","doi-asserted-by":"crossref","first-page":"168","DOI":"10.1016\/j.jep.2016.12.031","article-title":"The potential of aqueous extracts of Bellucia dichotoma Cogn. (Melastomataceae) to inhibit the biological activities of Bothrops atrox venom: A comparison of specimens collected in the states of Par\u00e1 and Amazonas, Brazil","volume":"196","author":"MOURA VM","year":"2017","journal-title":"J Ethnopharmacology"},{"key":"ref49","doi-asserted-by":"crossref","first-page":"1297","DOI":"10.1016\/j.biochi.2006.04.007","article-title":"Flavonoids inhibit the amidolytic activity of human thrombin","volume":"88","author":"MOZZICAFREDDO M","year":"2006","journal-title":"Biochimie"},{"key":"ref50","first-page":"1","article-title":"Implications of phytochemicals in snakebite management: presente status and future prospective","volume":"33","author":"NANJARAJ UAN","year":"2013","journal-title":"Toxin Reviews"},{"key":"ref51","doi-asserted-by":"crossref","first-page":"52","DOI":"10.4314\/ajtcam.v12i6.3S","article-title":"Anti-inflammatory medicinal plants and the molecular mechanisms underlying their activities","volume":"12","author":"NWORU CS","year":"2015","journal-title":"Afr J Tradit Complement Altern Med"},{"key":"ref52","doi-asserted-by":"crossref","first-page":"185","DOI":"10.5897\/AJFS2015.1402","article-title":"The role of nutraceuticals, functional foods and value added food products in the prevention and treatment of chronic diseases","volume":"10","author":"OLAIYA CO","year":"2016","journal-title":"African J Food Sci"},{"key":"ref53","doi-asserted-by":"crossref","first-page":"954","DOI":"10.1016\/j.foodres.2013.02.009","article-title":"A review on protein\u2013phenolic interactions and associated changes","volume":"51","author":"OZDAL T","year":"2013","journal-title":"Food Res Int"},{"issue":"11","key":"ref54","doi-asserted-by":"crossref","first-page":"1195","DOI":"10.1111\/bph.13649","article-title":"Antioxidants from black and green tea: from dietary modulation of oxidative stress to pharmacological mechanisms","volume":"174","author":"PELUSO SERAFINI M","year":"2017","journal-title":"British J Pharmacology"},{"key":"ref55","doi-asserted-by":"crossref","DOI":"10.1155\/2014\/670814","article-title":"The step further to understand the role of cytosolic phospholipase A2 alpha and group X secretory phospholipase A2 in allergic inflammation: pilot study","volume":"2014","author":"PNIEWSKA E","year":"2014","journal-title":"BioMed Res Int"},{"key":"ref56","doi-asserted-by":"crossref","first-page":"6071","DOI":"10.1074\/jbc.M115.700401","article-title":"How the linker connecting the two kringles influences activation and conformational plasticity of prothrombin","volume":"291","author":"POZZI N","year":"2016","journal-title":"J Biol Chem"},{"key":"ref57","first-page":"70","article-title":"Importance of Phytochemicals in nutraceuticals","volume":"1","author":"PRAKASH D","year":"2012","journal-title":"J Med Res Development"},{"key":"ref58","series-title":"R: A Language and Environment for Statistical Computing","year":"2012"},{"key":"ref59","doi-asserted-by":"crossref","first-page":"918","DOI":"10.1021\/bi035536m","article-title":"Apoptosis of insulin-secreting cells induced by endoplasmic reticulum stress is amplified by overexpression of group VIA calcium-independent phospholipase A2 (iPLA2 beta) and suppressed by inhibition of iPLA2 beta","volume":"3","author":"RAMANADHAM S","year":"2004","journal-title":"Biochemistry"},{"key":"ref60","doi-asserted-by":"crossref","first-page":"213","DOI":"10.1006\/abbi.2000.1958","article-title":"Structural and functional characterization of neuwiedase, a nonhemorrhagic fibrin (ogen)olytic metalloprotease from Bothrops neuwiedi snake venom","volume":"381","author":"RODRIGUES VM","year":"2000","journal-title":"Arch Biochem Biophys"},{"key":"ref61","first-page":"559","article-title":"The role of cytosolic phospholipase A2\u03b1 in amyloid precursor protein induction by amyloid beta1\u221242: implication for neurodegeneration","volume":"42","author":"SAGY-BROSS C","year":"2014","journal-title":"J Neurochem"},{"key":"ref62","doi-asserted-by":"crossref","first-page":"627","DOI":"10.1016\/j.toxicon.2011.01.006","article-title":"Haemostatically active proteins in snake venoms","volume":"57","author":"SAJEVIC T","year":"2011","journal-title":"Toxicon"},{"key":"ref63","doi-asserted-by":"crossref","first-page":"106","DOI":"10.2174\/138955713804484730","article-title":"Snake venom induced local toxicities, plant secondary metabolites as an auxiliary therapy","volume":"13","author":"SANTHOSH MS","year":"2013","journal-title":"Mini Rev Med Chem"},{"key":"ref64","doi-asserted-by":"crossref","first-page":"566","DOI":"10.1016\/j.jfoodeng.2008.10.005","article-title":"Effect of particle size on rheological properties of jaboticaba pulp","volume":"91","author":"SATO ACK","year":"2009","journal-title":"J Food Engineering"},{"key":"ref65","series-title":"Farmacognosia: Da Planta ao Medicamento. 6. Ed","volume-title":"Saponinas","author":"SCHENKEL EP","year":"2007"},{"key":"ref66","doi-asserted-by":"crossref","first-page":"261","DOI":"10.1016\/0041-0101(90)90062-C","article-title":"Isolation and characterization of hemorrhagic, myonecrotic and edema-inducing toxins from Bothrops insularis (jararaca ilhoa) snake venom","volume":"28","author":"SELISTRE HS","year":"1990","journal-title":"Toxicon"},{"key":"ref67","series-title":"Boca raton (FL)","volume-title":"HEATH BENEFITS OF TEA","author":"SERAFINI M","year":"2011"},{"key":"ref68","doi-asserted-by":"crossref","first-page":"95","DOI":"10.1021\/jm1013117","article-title":"Flavonoids with an oligopolysulfated moiety: a new class of anticoagulant agents","volume":"54","author":"SILVA MC","year":"2011","journal-title":"J Med Chem"},{"key":"ref69","doi-asserted-by":"crossref","first-page":"166","DOI":"10.1016\/j.jep.2016.02.043","article-title":"Connarus favosus Planch.: An inhibitor of the hemorrhagic activity of Bothrops atrox venom and a potential antioxidant and antibacterial agent","volume":"183","author":"SILVA TP","year":"2016","journal-title":"J Ethnopharmacology"},{"key":"ref70","doi-asserted-by":"crossref","first-page":"476","DOI":"10.1089\/wound.2014.0523","article-title":"Eicosanoids and Keratinocytes in Wound Healing","volume":"3","author":"SIVAMANI RK","year":"2014","journal-title":"Adv Wound Care"},{"key":"ref71","series-title":"Flavonoids and Related Compounds: Bioavailability and Function. Oxidative Stress and Disease, Vol. 30, edited by Packer L and Cadenas H","author":"SPENCER JPE","year":"2012"},{"key":"ref72","doi-asserted-by":"crossref","first-page":"15638","DOI":"10.3390\/ijms150915638","article-title":"Natural bioactive compounds from winery by-products as health promoters: a review","volume":"15","author":"TEIXEIRA A","year":"2014","journal-title":"Int J Mol Sci"},{"key":"ref73","series-title":"Encyclopedia of food sciences and nutrition. 2nd ed","first-page":"3623","volume-title":"Lupin","author":"TRUGO LC","year":"2003"},{"key":"ref74","doi-asserted-by":"crossref","first-page":"2983","DOI":"10.2174\/1381612821666150514104800","article-title":"Proteases and their receptors as mediators of inflammation-associated colon cancer","volume":"21","author":"TRUSEVYCH EH","year":"2015","journal-title":"Curr Pharm Des"},{"key":"ref75","doi-asserted-by":"crossref","first-page":"445","DOI":"10.1097\/01.fjc.0000176727.67066.1c","article-title":"Grape seed and skin extracts inhibit platelet function and release of reactive oxygen intermediates","volume":"46","author":"VITSEVA O","year":"2005","journal-title":"J Cardiovasc Pharmacol"},{"key":"ref76","first-page":"916","article-title":"Menopause: Resveratrol supplementation reduces pain experience by postmenopausal women","volume":"24","author":"WONG RHX","year":"2017","journal-title":"BioMed Sci"},{"key":"ref77","doi-asserted-by":"crossref","first-page":"33","DOI":"10.1016\/j.cofs.2016.02.002","article-title":"Dietary polyphenols, oxidative stress and antioxidant and anti-inflammatory effects","volume":"8","author":"ZHANG H","year":"2016","journal-title":"Current Opinion Food Sci"}],"container-title":["Anais da Academia Brasileira de Ci\u00eancias"],"original-title":[],"link":[{"URL":"http:\/\/www.scielo.br\/pdf\/aabc\/v91n2\/0001-3765-aabc-91-02-e20180248.pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2021,1,9]],"date-time":"2021-01-09T09:35:56Z","timestamp":1610184956000},"score":1,"resource":{"primary":{"URL":"http:\/\/www.scielo.br\/scielo.php?script=sci_arttext&pid=S0001-37652019000300613&tlng=en"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2019]]},"references-count":77,"journal-issue":{"issue":"2","published-online":{"date-parts":[[2019]]}},"alternative-id":["S0001-37652019000300613"],"URL":"https:\/\/doi.org\/10.1590\/0001-3765201920180248","relation":{},"ISSN":["1678-2690","0001-3765"],"issn-type":[{"value":"1678-2690","type":"electronic"},{"value":"0001-3765","type":"print"}],"subject":[],"published":{"date-parts":[[2019]]},"article-number":"e20180248"}}