{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,7,30]],"date-time":"2025-07-30T15:01:16Z","timestamp":1753887676211,"version":"3.41.2"},"reference-count":45,"publisher":"FapUNIFESP (SciELO)","issue":"4","license":[{"start":{"date-parts":[[2020,1,1]],"date-time":"2020-01-01T00:00:00Z","timestamp":1577836800000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"},{"start":{"date-parts":[[2020,1,1]],"date-time":"2020-01-01T00:00:00Z","timestamp":1577836800000},"content-version":"am","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"},{"start":{"date-parts":[[2020,1,1]],"date-time":"2020-01-01T00:00:00Z","timestamp":1577836800000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["An. Acad. Bras. Ci\u00eanc."],"DOI":"10.1590\/0001-3765202020200519","type":"journal-article","created":{"date-parts":[[2020,12,17]],"date-time":"2020-12-17T21:10:53Z","timestamp":1608239453000},"source":"Crossref","is-referenced-by-count":0,"title":["Oral and uterine leiomyomas exhibit high immunoexpression of Cripto-1 compared to normal myometrium"],"prefix":"10.1590","volume":"92","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-9048-703X","authenticated-orcid":false,"given":"ANDR\u00c9 F.","family":"SILVA","sequence":"first","affiliation":[{"name":"Universidade Federal do Rio Grande do Norte,  Brazil"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-1290-7238","authenticated-orcid":false,"given":"EMMILY C.C. DA","family":"SILVA","sequence":"additional","affiliation":[{"name":"Universidade Federal do Rio Grande do Norte,  Brazil"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-2853-320X","authenticated-orcid":false,"given":"CL\u00c1UDIA N.","family":"OLIVEIRA","sequence":"additional","affiliation":[{"name":"Universidade Federal do Rio Grande do Norte,  Brazil"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-0923-0094","authenticated-orcid":false,"given":"KEYLA B.F.","family":"ROCHA","sequence":"additional","affiliation":[{"name":"Universidade Federal do Rio Grande do Norte,  Brazil"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-6661-2566","authenticated-orcid":false,"given":"MARCIA C.C.","family":"MIGUEL","sequence":"additional","affiliation":[{"name":"Universidade Federal do Rio Grande do Norte,  Brazil"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-9141-6498","authenticated-orcid":false,"given":"JOABE S.","family":"PEREIRA","sequence":"additional","affiliation":[{"name":"Universidade Federal do Rio Grande do Norte,  Brazil"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"530","published-online":{"date-parts":[[2020]]},"reference":[{"key":"ref1","doi-asserted-by":"crossref","first-page":"767","DOI":"10.1016\/S0929-6646(08)60189-8","article-title":"Masson trichrome stain helps differentiate myofibroma from smooth muscle lesions in the head and neck region","volume":"107","author":"CHANG JY","year":"2008","journal-title":"J Formos Med Assoc"},{"key":"ref2","doi-asserted-by":"crossref","first-page":"555","DOI":"10.1530\/ERC-14-0102","article-title":"Regulation of estrogen receptor alpha function in oral squamous cell carcinoma cells by FAK signaling","volume":"21","author":"CHANG YL","year":"2014","journal-title":"Endocr Relat Cancer"},{"key":"ref3","doi-asserted-by":"crossref","first-page":"755","DOI":"10.1210\/jc.2010-0501","article-title":"Activin-A and myostatin response and steroid regulation in human myometrium: disruption of their signalling in uterine fibroid","volume":"96","author":"CIARMELA P","year":"2011","journal-title":"J Clin Endocrinol Metab"},{"key":"ref4","doi-asserted-by":"crossref","first-page":"772","DOI":"10.1093\/humupd\/dmr031","article-title":"Growth factors and myometrium: biological effects in uterine fibroid and possible clinical implications","volume":"17","author":"CIARMELA P","year":"2011","journal-title":"Hum Reprod Update"},{"key":"ref5","doi-asserted-by":"crossref","first-page":"941","DOI":"10.1007\/s11255-016-1248-5","article-title":"Urological complications of uterine leiomyoma: a review of literature","volume":"48","author":"DAGUR G","year":"2016","journal-title":"Int Urol Nephrol"},{"key":"ref6","doi-asserted-by":"crossref","first-page":"1127","DOI":"10.2217\/fon.10.68","article-title":"Cripto-1: an embryonic gene that promotes tumorigenesis","volume":"6","author":"DE CASTRO NP","year":"2010","journal-title":"Future Oncol"},{"year":"2017","series-title":"WHO classification of head and neck tumours","author":"EL-NAGGAR AK","key":"ref7"},{"key":"ref8","doi-asserted-by":"crossref","first-page":"1002","DOI":"10.1016\/S0959-8049(00)00033-2","article-title":"Clinicopathological implication of cripto expression in early stage invasive cervical carcinomas","volume":"36","author":"ERTOY D","year":"2000","journal-title":"Eur J Cancer"},{"key":"ref9","doi-asserted-by":"crossref","first-page":"856","DOI":"10.1097\/AOG.0b013e3182888478","article-title":"Surgical management of leiomyomas for fertility or uterine preservation","volume":"121","author":"FALCONE T","year":"2013","journal-title":"Obstet Gynecol"},{"key":"ref10","article-title":"The natural history of uterine leiomyomas: light and electron microscopic studies of fibroid phases, interstitial ischemia, inanosis, and reclamation","volume":"2013","author":"FLAKE GP","year":"2013","journal-title":"Obstet Gynecol Int"},{"key":"ref11","first-page":"483","article-title":"Vascular leiomyoma of the oral cavity","volume":"13","author":"GAITAN CEPEDA LA","year":"2008","journal-title":"Med Oral Patol Oral Cir Bucal"},{"key":"ref12","first-page":"9","article-title":"Leiomyoma of oral cavity: case report and literature review","volume":"2","author":"GIANLUCA S","year":"2011","journal-title":"Ann Stomatol"},{"key":"ref13","doi-asserted-by":"crossref","first-page":"618","DOI":"10.1016\/j.prp.2011.07.002","article-title":"The role of mast cells and angiogenesis in benign and malignant neoplasms of the uterus","volume":"207","author":"GOKSU EROL AY","year":"2011","journal-title":"Pathol Res Pract"},{"key":"ref14","first-page":"554","article-title":"Estrogen and Progesterone hormone receptor expression in oral cavity cancer","volume":"21","author":"GRIMM M","year":"2016","journal-title":"Med Oral Patol Oral Cir Bucal"},{"key":"ref15","doi-asserted-by":"crossref","first-page":"59","DOI":"10.1093\/humupd\/dmx032","article-title":"Extracellular matrix in uterine leiomyoma pathogenesis: a potential target for future therapeutics","volume":"24","author":"ISLAM MS","year":"2018","journal-title":"Hum Reprod Update"},{"key":"ref16","doi-asserted-by":"crossref","first-page":"25","DOI":"10.1016\/j.bpobgyn.2015.08.018","article-title":"Growth factors and pathogenesis","volume":"34","author":"ISLAM MS","year":"2016","journal-title":"Best Pract Res Clin Obstet Gynaecol"},{"key":"ref17","doi-asserted-by":"crossref","first-page":"921","DOI":"10.1210\/jc.2012-3237","article-title":"Uterine leiomyoma: available medical treatments and new possible therapeutic options","volume":"98","author":"ISLAM MS","year":"2013","journal-title":"J Clin Endocrinol Metab"},{"key":"ref18","doi-asserted-by":"crossref","first-page":"178","DOI":"10.1016\/j.fertnstert.2013.03.007","article-title":"Complex networks of multiple factors in the pathogenesis of uterine leiomyoma","volume":"100","author":"ISLAM MS","year":"2013","journal-title":"Fertil Steril"},{"key":"ref19","doi-asserted-by":"crossref","first-page":"1273","DOI":"10.1242\/dev.01706","article-title":"TGFbeta\/activin\/nodal signaling is necessary for the maintenance of pluripotency in human embryonic stem cells","volume":"132","author":"JAMES D","year":"2005","journal-title":"Development"},{"key":"ref20","doi-asserted-by":"crossref","first-page":"773","DOI":"10.2741\/4140","article-title":"Role of mast cells in gynecological neoplasms","volume":"18","author":"JIANG L","year":"2013","journal-title":"Front Biosci"},{"year":"2014","series-title":"WHO classification of tumours of female reproductive organs","author":"KURMAN RJ","key":"ref21"},{"key":"ref22","doi-asserted-by":"crossref","first-page":"241","DOI":"10.3892\/ol.2014.2124","article-title":"Angioleiomyomas in the head and neck: A retrospective clinical and immunohistochemical analysis","volume":"8","author":"LIU Y","year":"2014","journal-title":"Oncol Lett"},{"key":"ref23","doi-asserted-by":"crossref","first-page":"311","DOI":"10.1007\/s12105-013-0497-1","article-title":"Extensively ossifying oral leiomyoma: a rare histologic finding","volume":"8","author":"MONTAGUE LJ","year":"2014","journal-title":"Head Neck Pathol"},{"key":"ref24","first-page":"192","article-title":"Leiomyoma: Its Variants And Secondary Changes A Five-Year Study","volume":"31","author":"NAZ S","year":"2019","journal-title":"J Ayub Med Coll Abbottabad"},{"year":"2016","series-title":"Oral and maxillofacial pathology","author":"NEVILLE BW","key":"ref25"},{"key":"ref26","doi-asserted-by":"crossref","DOI":"10.1590\/S1808-86942010000400022","article-title":"Oral vascular leiomyoma with extensive calcification areas","volume":"76","author":"NONAKA CF","year":"2010","journal-title":"Braz J Otorhinolaryngol"},{"key":"ref27","doi-asserted-by":"crossref","first-page":"293","DOI":"10.1007\/BF00665981","article-title":"Expression of messenger RNA for amphiregulin, heregulin, and cripto-1, three new members of the epidermal growth factor family, in human breast carcinomas","volume":"35","author":"NORMANNO N","year":"1995","journal-title":"Breast Cancer Res Treat"},{"year":"2009","series-title":"Gynecologic pathology","author":"NUCCI MR","key":"ref28"},{"key":"ref29","doi-asserted-by":"crossref","first-page":"51","DOI":"10.1002\/(SICI)1097-0215(19960103)65:1<51::AID-IJC9>3.0.CO;2-0","article-title":"Differential immunohistochemical detection of transforming growth factor alpha, amphiregulin and CRIPTO in human normal and malignant breast tissues","volume":"65","author":"PANICO L","year":"1996","journal-title":"Int J Cancer"},{"key":"ref30","doi-asserted-by":"crossref","first-page":"415","DOI":"10.1007\/s00441-015-2324-3","article-title":"Possible involvement of inflammatory\/reparative processes in the development of uterine fibroids","volume":"364","author":"PROTIC O","year":"2016","journal-title":"Cell Tissue Res"},{"key":"ref31","doi-asserted-by":"crossref","first-page":"211","DOI":"10.1007\/s10549-016-3746-7","article-title":"Developmental signaling pathways regulating mammary stem cells and contributing to the etiology of triple-negative breast cancer","volume":"156","author":"RANGEL MC","year":"2016","journal-title":"Breast Cancer Res Treat"},{"key":"ref32","doi-asserted-by":"crossref","first-page":"43","DOI":"10.1016\/j.gene.2011.05.007","article-title":"Molecular evolution of the EGF-CFC protein family","volume":"482","author":"RAVISANKAR V","year":"2011","journal-title":"Gene"},{"key":"ref33","doi-asserted-by":"crossref","first-page":"231","DOI":"10.1016\/j.archoralbio.2010.09.020","article-title":"Immunohistochemical expression of mast cell tryptase in giant cell fibroma and inflammatory fibrous hyperplasia of the oral mucosa","volume":"56","author":"SANTOS PP","year":"2011","journal-title":"Arch Oral Biol"},{"key":"ref34","doi-asserted-by":"crossref","first-page":"676","DOI":"10.1038\/nmeth.2019","article-title":"Fiji: an open-source platform for biological-image analysis","volume":"9","author":"SCHINDELIN J","year":"2012","journal-title":"Nat Methods"},{"key":"ref35","doi-asserted-by":"crossref","first-page":"1595","DOI":"10.1007\/s00405-018-4960-1","article-title":"Cripto-1 is overexpressed in carcinoma ex pleomorphic adenoma of salivary gland","volume":"275","author":"SILVA LP","year":"2018","journal-title":"Eur Arch Otorhinolaryngol"},{"key":"ref36","first-page":"1646","article-title":"Clinical practice","volume":"372","author":"STEWART EA","year":"2015","journal-title":"N Engl J Med"},{"key":"ref37","doi-asserted-by":"crossref","first-page":"36","DOI":"10.1002\/path.2083","article-title":"Development of leiomyosarcoma of the uterus in MMTV-CR-1 transgenic mice","volume":"211","author":"STRIZZI L","year":"2007","journal-title":"J Pathol"},{"year":"2013","series-title":"Bancroft\u2019s theory and practice of histological techniques","author":"SUVARNA SK","key":"ref38"},{"key":"ref39","first-page":"4203","article-title":"Immunohistochemical quantification of the vitamin B12 transport protein (TCII), cell surface receptor (TCII-R) and Ki-67 in human tumor xenografts","volume":"33","author":"SYSEL AM","year":"2013","journal-title":"Anticancer Res"},{"key":"ref40","doi-asserted-by":"crossref","first-page":"281","DOI":"10.4103\/0973-029X.119770","article-title":"Leiomyoma: A rare tumor in the head and neck and oral cavity: Report of 3 cases with review","volume":"17","author":"VEERESH M","year":"2013","journal-title":"J Oral Maxillofac Pathol"},{"key":"ref41","doi-asserted-by":"crossref","first-page":"226","DOI":"10.1016\/j.mehy.2012.04.046","article-title":"Are uterine leiomyoma a consequence of a chronically inflammatory immune system","volume":"79","author":"WEGIENKA G","year":"2012","journal-title":"Med Hypotheses"},{"year":"2007","series-title":"Enzinger and Weiss\u2019s Soft Tissue Tumors","author":"WEISS SW","key":"ref42"},{"year":"2020","series-title":"Soft tissue and bone tumours","author":"WHO EJ","key":"ref43"},{"key":"ref44","doi-asserted-by":"crossref","first-page":"830","DOI":"10.1038\/modpathol.2015.35","article-title":"Biomarker resolution of uterine smooth muscle tumor necrosis as benign vs malignant","volume":"28","author":"YANG EJ","year":"2015","journal-title":"Mod Pathol"},{"key":"ref45","doi-asserted-by":"crossref","first-page":"1023","DOI":"10.1016\/j.oraloncology.2011.07.019","article-title":"The role of Cripto-1 in the tumorigenesis and progression of oral squamous cell carcinoma","volume":"47","author":"YOON HJ","year":"2011","journal-title":"Oral Oncol"}],"container-title":["Anais da Academia Brasileira de Ci\u00eancias"],"original-title":[],"link":[{"URL":"http:\/\/www.scielo.br\/pdf\/aabc\/v92n4\/0001-3765-aabc-92-04-e20200519.pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2021,1,24]],"date-time":"2021-01-24T02:36:51Z","timestamp":1611455811000},"score":1,"resource":{"primary":{"URL":"http:\/\/www.scielo.br\/scielo.php?script=sci_arttext&pid=S0001-37652020000700936&tlng=en"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2020]]},"references-count":45,"journal-issue":{"issue":"4","published-online":{"date-parts":[[2020]]}},"alternative-id":["S0001-37652020000700936"],"URL":"https:\/\/doi.org\/10.1590\/0001-3765202020200519","relation":{},"ISSN":["1678-2690","0001-3765"],"issn-type":[{"type":"electronic","value":"1678-2690"},{"type":"print","value":"0001-3765"}],"subject":[],"published":{"date-parts":[[2020]]},"article-number":"e20200519"}}