{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,7]],"date-time":"2026-07-07T01:37:00Z","timestamp":1783388220546,"version":"3.54.6"},"reference-count":60,"publisher":"FapUNIFESP (SciELO)","issue":"1","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Arq Bras Endocrinol Metab"],"published-print":{"date-parts":[[2014,2]]},"abstract":"<jats:p>Vitamin D deficiency and diabetes mellitus are two common conditions and they are widely prevalent across all ages, races, geographical regions, and socioeconomic conditions. Epidemiologic studies have shown association of vitamin D deficiency and increased risk of chronic diseases, such as cancer, cardiovascular disease, type 2 diabetes, and autoimmune diseases, such as multiple sclerosis and type 1 diabetes mellitus. The identification of 1,25(OH)2D receptors and 1-\u03b1-hydroxilase expression in pancreatic beta cells, in cells of the immune system, and in various others tissues, besides the bone system support the role of vitamin D in the pathogenesis of type 2 diabetes. Observational studies have revealed an association between 25(OH) D deficiency and the prevalence of type 1 diabetes in children and adolescents. This review will focus on the concept of vitamin D deficiency, its prevalence, and its role in the pathogenesis and risk of diabetes mellitus and cardiovascular diseases.<\/jats:p>","DOI":"10.1590\/0004-2730000002535","type":"journal-article","created":{"date-parts":[[2014,3,31]],"date-time":"2014-03-31T15:15:50Z","timestamp":1396278950000},"page":"1-8","source":"Crossref","is-referenced-by-count":28,"title":["Vitamin D and diabetes mellitus: an update 2013"],"prefix":"10.1590","volume":"58","author":[{"given":"Luiz Henrique Maciel","family":"Griz","sequence":"first","affiliation":[{"name":"Universidade Federal de Pernambuco, Brazil"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Francisco","family":"Bandeira","sequence":"additional","affiliation":[{"name":"Universidade Federal de Pernambuco, Brazil"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"M\u00f4nica Andrade Lima","family":"Gabbay","sequence":"additional","affiliation":[{"name":"Universidade 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