{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,3]],"date-time":"2026-10-03T04:10:20Z","timestamp":1791000620731,"version":"4.1.0"},"reference-count":60,"publisher":"FapUNIFESP (SciELO)","issue":"4","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Arq Bras Endocrinol Metab"],"published-print":{"date-parts":[[2014,6]]},"abstract":"<jats:p>A microbiota intestinal, adquirida no per\u00edodo p\u00f3s-natal, \u00e9 composta por grande diversidade de bact\u00e9rias que desempenham diferentes fun\u00e7\u00f5es no hospedeiro humano, entre elas a absor\u00e7\u00e3o de nutrientes, prote\u00e7\u00e3o contra pat\u00f3genos e modula\u00e7\u00e3o do sistema imune. O conte\u00fado bacteriano intestinal ainda n\u00e3o \u00e9 totalmente conhecido, mas sabe-se que \u00e9 influenciado por fatores internos e principalmente externos que modulam sua composi\u00e7\u00e3o e fun\u00e7\u00e3o. Estudos indicam que a microbiota intestinal difere em indiv\u00edduos magros e obesos e ainda naqueles que mant\u00eam h\u00e1bitos alimentares diferentes. H\u00e1 evid\u00eancias de que as rela\u00e7\u00f5es entre dieta, inflama\u00e7\u00e3o, resist\u00eancia \u00e0 insulina e risco cardiometab\u00f3lico s\u00e3o em parte mediadas pela composi\u00e7\u00e3o de bact\u00e9rias intestinais. Conhecimentos sobre a microbiota poder\u00e3o reverter em diferentes estrat\u00e9gias para manipular as popula\u00e7\u00f5es bacterianas e promover sa\u00fade. Esta revis\u00e3o aborda a relev\u00e2ncia do conhecimento sobre o papel de fatores ou padr\u00f5es alimentares na composi\u00e7\u00e3o da microbiota, assim como mecanismos fisiopatol\u00f3gicos de doen\u00e7as metab\u00f3licas cr\u00f4nicas e as potencialidades de prebi\u00f3ticos e probi\u00f3ticos sobre o perfil de risco cardiometab\u00f3lico.<\/jats:p>","DOI":"10.1590\/0004-2730000002940","type":"journal-article","created":{"date-parts":[[2014,6,16]],"date-time":"2014-06-16T20:26:53Z","timestamp":1402950413000},"page":"317-327","source":"Crossref","is-referenced-by-count":28,"title":["Microbiota intestinal e risco cardiometab\u00f3lico: mecanismos e modula\u00e7\u00e3o diet\u00e9tica"],"prefix":"10.1590","volume":"58","author":[{"given":"Ana Carolina Franco de","family":"Moraes","sequence":"first","affiliation":[{"name":"Universidade de S\u00e3o Paulo, Brasil"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Isis Tande 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