{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,5]],"date-time":"2026-10-05T13:53:46Z","timestamp":1791208426032,"version":"4.1.0"},"reference-count":67,"publisher":"FapUNIFESP (SciELO)","issue":"5","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Arq Bras Endocrinol Metab"],"published-print":{"date-parts":[[2014,7]]},"abstract":"<jats:p>Until recently obesity was believed to be protective against fractures. However, a report from a Fracture Liaison Clinic in the UK (2010) reported a surprisingly high proportion of obese postmenopausal women attending the clinic with fractures, and in the GLOW study (2011), a similar prevalence and incidence of fractures in obese and non-obese postmenopausal women was observed. Subsequently, other studies have demonstrated the importance of obesity in the epidemiology of fractures. Obese women are at increased risk of fracture in ankle, leg, humerus, and vertebral column and at lower risk of wrist, hip and pelvis fracture when compared to non-obese women. In men, it has been reported that multiple rib fractures are associated with obesity. Furthermore, falls appear to play an important role in the pathogenesis of fractures in obese subjects. Regarding hip fracture and major fractures, the FRAX algorithm has proven to be a useful predictor in obese individuals. Obese people are less likely to receive bone protective treatment; they have a longer hospital stay and a lower quality of life both before and after fracture. Moreover, the efficacy of antiresorptive therapies is not well established in obese people. The latter is a field for future research.<\/jats:p>","DOI":"10.1590\/0004-2730000003274","type":"journal-article","created":{"date-parts":[[2014,8,20]],"date-time":"2014-08-20T18:57:27Z","timestamp":1408561047000},"page":"470-477","source":"Crossref","is-referenced-by-count":54,"title":["Obesity and fractures"],"prefix":"10.1590","volume":"58","author":[{"given":"Melissa Orlandin","family":"Premaor","sequence":"first","affiliation":[{"name":"Federal University of Santa Maria, Brazil"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Fabio Vasconcellos","family":"Comim","sequence":"additional","affiliation":[{"name":"Federal University of Santa Maria, Brazil"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Juliet E.","family":"Compston","sequence":"additional","affiliation":[{"name":"Cambridge Biomedical Campus, United Kingdom"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"530","reference":[{"issue":"9765","key":"ref1","doi-asserted-by":"crossref","first-page":"557","DOI":"10.1016\/S0140-6736(10)62037-5","article-title":"National, regional, and global trends in body-mass index since 1980: systematic analysis of health examination surveys and epidemiological studies with 960 country-years and 9.1 million participants","volume":"377","author":"Finucane MM","year":"2011","journal-title":"Lancet"},{"key":"ref2","article-title":"The incidence of co-morbidities related to obesity and overweight: a systematic review and meta-analysis","volume":"9","author":"Guh DP","year":"2009","journal-title":"BMC public health"},{"issue":"1-2","key":"ref3","doi-asserted-by":"crossref","DOI":"10.1007\/s11657-013-0136-1","article-title":"Osteoporosis in the European Union: medical management, epidemiology and economic burden. 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