{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,5,12]],"date-time":"2025-05-12T15:46:15Z","timestamp":1747064775434,"version":"3.40.4"},"reference-count":63,"publisher":"FapUNIFESP (SciELO)","issue":"5","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Arq Bras Endocrinol Metab"],"published-print":{"date-parts":[[2014,7]]},"abstract":"<jats:p>Aging is associated with decreases in bone quality and in glomerular filtration. Consequently, osteoporosis and chronic kidney disease (CKD) are common comorbid conditions in the elderly, and often coexist. Biochemical abnormalities in the homeostasis of calcium and phosphorus begin early in CKD, leading to an increase in fracture risk and cardiovascular complications since early stages of the disease. The ability of DXA (dual energy X-ray absorptiometry) to diagnose osteoporosis and to predict fractures in this population remains unclear. The management of the disease is also controversial: calcium and vitamin D, although recommended, must be prescribed with caution, considering vascular calcification risk and the development of adynamic bone disease. Furthermore, safety and effectiveness of osteoporosis drugs are not established in patients with CKD. Thus, risks and benefits of antiosteoporosis treatment must be considered individually.<\/jats:p>","DOI":"10.1590\/0004-2730000003360","type":"journal-article","created":{"date-parts":[[2014,8,20]],"date-time":"2014-08-20T18:56:51Z","timestamp":1408561011000},"page":"530-539","source":"Crossref","is-referenced-by-count":10,"title":["Osteoporosis management in patient with renal function impairment"],"prefix":"10.1590","volume":"58","author":[{"given":"Guilherme Alcantara Cunha","family":"Lima","sequence":"first","affiliation":[{"name":"Universidade Federal do Rio de Janeiro, Brazil"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Francisco de Paula","family":"Paranhos Neto","sequence":"additional","affiliation":[{"name":"Universidade Federal do Rio de Janeiro, Brazil"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Giselly Rosa Modesto","family":"Pereira","sequence":"additional","affiliation":[{"name":"Universidade Federal Fluminense, Brazil"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Carlos Perez","family":"Gomes","sequence":"additional","affiliation":[{"name":"UFRJ, Brazil"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Maria Lucia Fleiuss","family":"Farias","sequence":"additional","affiliation":[{"name":"Universidade Federal do Rio de Janeiro, Brazil"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"530","reference":[{"key":"ref1","first-page":"S1","article-title":"KDIGO 2012 Clinical Practice Guideline for the Evaluation and Management of Chronic Kidney Disease","volume":"3","year":"2013","journal-title":"Kidney Int"},{"key":"ref2","doi-asserted-by":"crossref","first-page":"1310","DOI":"10.1111\/j.1523-1755.2004.00894.x","article-title":"The burden of kidney disease: improving global outcomes (KDIGO)","volume":"66","author":"Eknoyan G","year":"2004","journal-title":"Kidney Int"},{"key":"ref3","doi-asserted-by":"crossref","first-page":"603","DOI":"10.7326\/0003-4819-150-9-200905050-00006","article-title":"CKD-EPI (Chronic Kidney Disease Epidemiology Collaboration). 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