{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2024,7,31]],"date-time":"2024-07-31T14:34:56Z","timestamp":1722436496284},"reference-count":33,"publisher":"FapUNIFESP (SciELO)","issue":"5","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Arq. Neuro-Psiquiatr."],"published-print":{"date-parts":[[2013,5]]},"abstract":"<jats:p>Objective:It was to assess the main characteristics of patients undergoing pituitary tumor surgery.Method:Eighty-seven patients (44 men; 44.8\u00b113 years old) were included.Results:The main symptoms were visual alterations (87.3%), headache (70.1%), diminished libido (34.4%), galactorrhea (22.9%) and hair loss (19.5%). The axes affected were gonadotropic (72.6%), thyrotropic (48.4%) and corticotropic (38.7%), without significant changes after surgery. The average largest tumor diameter was 3.1 cm before surgery and 1.56 cm after surgery. The most frequent postoperative complications were hydro-electrolyte and acid-base disorders (12%), diabetes insipidus (9%), visual field alterations (9%), liquoric fistula (8%) and nasal obstruction (7%). The patients were affected by more than one complication.Conclusion:Although a decrease in tumor volume was achieved through surgery, hormonal deficiencies persisted in most of the patients and new surgical approaches were necessary for dealing with tumor recurrence or persistence.<\/jats:p>","DOI":"10.1590\/0004-282x20130026","type":"journal-article","created":{"date-parts":[[2013,8,14]],"date-time":"2013-08-14T20:26:53Z","timestamp":1376512013000},"page":"307-312","source":"Crossref","is-referenced-by-count":7,"title":["Clinical and laboratorial characterization and post-surgical follow-up of 87 patients with non-functioning pituitary macroadenomas"],"prefix":"10.1590","volume":"71","author":[{"given":"Paulo Andrade de","family":"Mello","sequence":"first","affiliation":[{"name":"Universidade de Bras\u00edlia,  Brazil"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Luciana Ansaneli","family":"Naves","sequence":"additional","affiliation":[{"name":"UnB,  Brazil"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Aldo","family":"Pereira Neto","sequence":"additional","affiliation":[{"name":"Universidade de Bras\u00edlia,  Brazil"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Eduardo Henrique","family":"Oliveira","sequence":"additional","affiliation":[{"name":"UnB,  Brazil"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ivan Coelho","family":"Ferreira","sequence":"additional","affiliation":[{"name":"UnB,  Brazil"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ant\u00f4nio Santos de","family":"Ara\u00fajo J\u00fanior","sequence":"additional","affiliation":[{"name":"UnB,  Brazil"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Franz Jooji","family":"Onishi","sequence":"additional","affiliation":[{"name":"UnB,  Brazil"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Luiz Augusto","family":"Casulari","sequence":"additional","affiliation":[{"name":"UnB,  Brazil"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"530","reference":[{"key":"ref1","series-title":"Endocrinologia Cl\u00ednica.","first-page":"101","volume-title":"Adenomas hipofis\u00e1rios cl\u00ednicamente n\u00e3o-funcionantes","author":"Naves LA","year":"2009","edition":"4. ed"},{"key":"ref2","doi-asserted-by":"crossref","first-page":"455","DOI":"10.1590\/S0004-27302000000600004","article-title":"Tratamento medicamentoso dos tumores hipofis\u00e1rios. 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