{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,4,5]],"date-time":"2026-04-05T05:34:27Z","timestamp":1775367267240,"version":"3.50.1"},"reference-count":25,"publisher":"FapUNIFESP (SciELO)","issue":"7","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Arq. Neuro-Psiquiatr."],"published-print":{"date-parts":[[2013,7]]},"abstract":"<jats:p>ObjectiveIt was to investigate visual field (VF) abnormalities in a group of multiple sclerosis (MS) patients in the remission phase and the presence of magnetic resonance imaging (MRI) lesions in the optic radiations.MethodsVF was assessed in 60 participants (age range 20-51 years): 35 relapsing-remitting MS patients [20 optic neuritis (+), 15 optic neuritis (-)] and 25 controls. MRI (3-Tesla) was obtained in all patients.ResultsVisual parameters were abnormal in MS patients as compared to controls. The majority of VF defects were diffuse. All patients except one had posterior visual pathways lesions. No significant difference in lesion number, length and distribution was noted between patients with and without history of optic neuritis. One patient presented homonymous hemianopsia.ConclusionPosterior visual pathway abnormalities were found in most MS patients despite history of previous optic neuritis.<\/jats:p>","DOI":"10.1590\/0004-282x20130058","type":"journal-article","created":{"date-parts":[[2013,8,14]],"date-time":"2013-08-14T20:27:06Z","timestamp":1376512026000},"page":"437-441","source":"Crossref","is-referenced-by-count":15,"title":["Visual pathway abnormalities were found in most multiple sclerosis patients despite history of previous optic neuritis"],"prefix":"10.1590","volume":"71","author":[{"given":"Stella Maris Costa","family":"Castro","sequence":"first","affiliation":[{"name":"Universidade Estadual de Campinas,  Brazil"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Alfredo","family":"Damasceno","sequence":"additional","affiliation":[{"name":"UNICAMP,  Brazil"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Benito Pereira","family":"Damasceno","sequence":"additional","affiliation":[{"name":"UNICAMP,  Brazil"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jose Paulo de","family":"Vasconcellos","sequence":"additional","affiliation":[{"name":"Universidade Estadual de Campinas,  Brazil"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Fabiano","family":"Reis","sequence":"additional","affiliation":[{"name":"UNICAMP,  Brazil"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Josie Naomi","family":"Iyeyasu","sequence":"additional","affiliation":[{"name":"Universidade Estadual de Campinas,  Brazil"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Keila Monteiro de","family":"Carvalho","sequence":"additional","affiliation":[{"name":"Universidade Estadual de Campinas,  Brazil"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"530","reference":[{"key":"ref1","doi-asserted-by":"crossref","first-page":"81","DOI":"10.1016\/j.pathophys.2010.04.009","article-title":"Optic neuritis: a mechanistic view","volume":"18","author":"Burton EV","year":"2011","journal-title":"Pathophysiology"},{"key":"ref2","doi-asserted-by":"crossref","first-page":"315","DOI":"10.1136\/jnnp.25.4.315","article-title":"The distribution of plaques in the cerebrum in multiple sclerosis","volume":"25","author":"Brownell B","year":"1962","journal-title":"J Neurol Neurosurg Psychiatry"},{"key":"ref3","doi-asserted-by":"crossref","first-page":"77","DOI":"10.1212\/WNL.42.1.77","article-title":"Frequent involvement of the optic radiation in patients with acute isolated optic neuritis","volume":"42","author":"Hornabrook RS","year":"1992","journal-title":"Neurology"},{"key":"ref4","doi-asserted-by":"crossref","first-page":"68","DOI":"10.1212\/WNL.42.1.68","article-title":"Symptomatic retrochiasmal lesions in multiple sclerosis: clinical features, visual evoked potentials, and magnetic resonance imaging","volume":"42","author":"Plant GT","year":"1992","journal-title":"Neurology"},{"key":"ref5","first-page":"1079","year":"2008"},{"key":"ref6","doi-asserted-by":"crossref","first-page":"1162","DOI":"10.1001\/archopht.120.9.1162","article-title":"Can Swedish interactive thresholding algorithm fast perimetry be used as an alternative to goldmann perimetry in neuro-ophthalmic practice?","volume":"120","author":"Szatmary G","year":"2002","journal-title":"Arch Ophthalmol"},{"key":"ref7","doi-asserted-by":"crossref","first-page":"946","DOI":"10.1001\/archopht.1994.01090190094027","article-title":"Visual field profile of optic neuritis. 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