{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,14]],"date-time":"2026-09-14T06:02:21Z","timestamp":1789365741713,"version":"build-2803163510"},"reference-count":21,"publisher":"FapUNIFESP (SciELO)","issue":"1","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Arq. Neuro-Psiquiatr."],"published-print":{"date-parts":[[2015,1]]},"abstract":"<jats:p>ObjectiveAnalyze the cases of posterior reversible encephalopathy syndrome (PRES) admitted in a Neurology Department during an 8-year period.MethodRetrospective observational study in a central hospital in the north of Portugal.Results14 patients were identified, mean age 52.3 years. Precipitating factors included: eclampsia, isolated arterial hypertension, spinal trauma and autonomic dysreflexia, Guillain-Barr\u00e9 syndrome, sepsis, sarcoidosis and pulmonary cryptococcosis and drugs. Most patients presented posterior-predominant vasogenic edema lesions, however 64.2% presented frontal lesions and in 42.8% cerebellum was involved. Four patients also had acute ischemic lesions and 1 had hemorrhagic lesions. During follow-up 10 patients recovered fully, 2 recovered partially, 1 suffered a recurrence and 2 died in hospital.ConclusionPRES has many etiological factors. The terms posterior and reversible should be revised because PRES frequently involves other brain regions and it is not always reversible. PRES patients may develop life-threatening complications and mortality is not negligible.<\/jats:p>","DOI":"10.1590\/0004-282x20140176","type":"journal-article","created":{"date-parts":[[2015,1,17]],"date-time":"2015-01-17T20:47:08Z","timestamp":1421527628000},"page":"36-40","source":"Crossref","is-referenced-by-count":19,"title":["Clinical, imagiological and etiological spectrum of posterior reversible encephalopathy syndrome"],"prefix":"10.1590","volume":"73","author":[{"given":"P Ricardo","family":"Pereira","sequence":"first","affiliation":[{"name":"Hospital Pedro Hispano,  Portugal"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jo\u00e3o","family":"Pinho","sequence":"additional","affiliation":[{"name":"Hospital de Braga,  Portugal"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Margarida","family":"Rodrigues","sequence":"additional","affiliation":[{"name":"Hospital de Braga,  Portugal"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jo\u00e3o","family":"Rocha","sequence":"additional","affiliation":[{"name":"Hospital de Braga,  Portugal"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Filipa","family":"Sousa","sequence":"additional","affiliation":[{"name":"Hospital de Braga,  Portugal"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jos\u00e9","family":"Amorim","sequence":"additional","affiliation":[{"name":"Hospital de Braga,  Portugal"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Manuel","family":"Ribeiro","sequence":"additional","affiliation":[{"name":"Hospital de Braga,  Portugal"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jaime","family":"Rocha","sequence":"additional","affiliation":[{"name":"Hospital de Braga,  Portugal"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Carla","family":"Ferreira","sequence":"additional","affiliation":[{"name":"Hospital 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Neuroimaging"},{"key":"ref8","doi-asserted-by":"crossref","first-page":"1320","DOI":"10.3174\/ajnr.A0549","article-title":"Distinct imaging patterns and lesion distribution in posterior reversible encephalopathy syndrome","volume":"28","author":"Bartynski WS","year":"2007","journal-title":"Am J Neuroradiol"},{"key":"ref9","doi-asserted-by":"crossref","first-page":"453","DOI":"10.1097\/PHM.0b013e3182744889","article-title":"Autonomic dysreflexia and posterior reversible encephalopathy syndrome","volume":"92","author":"Matias AC","year":"2013","journal-title":"Am J Phys Med Rehabil"},{"key":"ref10","doi-asserted-by":"crossref","DOI":"10.1111\/j.1445-5994.2004.00750.x","article-title":"Reversible posterior leukoencephalopathy syndrome: a misnomer reviewed","volume":"35","author":"Stott VL","year":"2005","journal-title":"Intern Med J"},{"key":"ref11","doi-asserted-by":"crossref","first-page":"155","DOI":"10.1007\/s00415-011-6152-4","article-title":"The clinical and radiological spectrum of posterior reversible encephalopathy syndrome: the retrospective Berlin PRES study","volume":"259","author":"Liman TG","year":"2012","journal-title":"J Neurol"},{"key":"ref12","doi-asserted-by":"crossref","first-page":"1566","DOI":"10.1259\/bjr\/25273221","article-title":"The many faces of posterior reversible encephalopathy syndrome","volume":"85","author":"Stevens CJ","year":"2012","journal-title":"Br J Radiol"},{"key":"ref13","doi-asserted-by":"crossref","first-page":"427","DOI":"10.4065\/mcp.2009.0590","article-title":"Posterior reversible encephalopathy syndrome: associated clinical and radiological findings","volume":"85","author":"Fugate JE","year":"2010","journal-title":"Mayo Clin Proc"},{"key":"ref14","doi-asserted-by":"crossref","first-page":"411","DOI":"10.1016\/S0140-6736(00)02539-3","article-title":"Hypertensive emergencies","volume":"356","author":"Vaughan CJ","year":"2000","journal-title":"Lancet"},{"key":"ref15","doi-asserted-by":"crossref","first-page":"1174","DOI":"10.1212\/WNL.49.4.1174","article-title":"Post-transfusion reversible posterior leukoencephalopathy syndrome with cerebral vasoconstriction","volume":"49","author":"Ito Y","year":"1997","journal-title":"Neurology"},{"key":"ref16","doi-asserted-by":"crossref","first-page":"54","DOI":"10.2169\/internalmedicine.38.54","article-title":"Two similar cases of encephalopathy, possibly a reversible posterior leukoencephalopathy syndrome: serial findings of magnetic resonance imaging, SPECT and angiography","volume":"38","author":"Tajima Y","year":"1999","journal-title":"Intern Med"},{"key":"ref17","series-title":"Critical care neurology and neurosurgery","first-page":"247","volume-title":"Blood pressure management in the neurocritical care patient","author":"Ziai WC","year":"2004"},{"key":"ref18","doi-asserted-by":"crossref","first-page":"253","DOI":"10.1007\/s11523-011-0201-x","article-title":"Posterior reversible encephalopathy syndrome induced by anti-VEGF agents","volume":"6","author":"Tlemsani C","year":"2011","journal-title":"Targ Oncol"},{"key":"ref19","doi-asserted-by":"crossref","first-page":"25","DOI":"10.1159\/000117195","article-title":"Parietal occipital edema in hypertensive encephalopathy: a pathogenic mechanism","volume":"36","author":"Sheth RD","year":"1996","journal-title":"Eur Neurol"},{"key":"ref20","doi-asserted-by":"crossref","first-page":"447","DOI":"10.3174\/ajnr.A0839","article-title":"Catheter angiography, MR angiography, and MR perfusion in posterior reversible encephalopathy syndrome","volume":"29","author":"Bartynski WS","year":"2008","journal-title":"AJNR Am J Neuroradiol"},{"key":"ref21","doi-asserted-by":"crossref","first-page":"24","DOI":"10.1136\/pmj.77.903.24","article-title":"Posterior leukoencephalopathy 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