{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,16]],"date-time":"2026-10-16T21:07:57Z","timestamp":1792184877945,"version":"4.4.0"},"reference-count":26,"publisher":"FapUNIFESP (SciELO)","issue":"4","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Arq. Neuro-Psiquiatr."],"published-print":{"date-parts":[[2015,4]]},"abstract":"<jats:p>Spine is the most common site for skeletal metastasis in patients with malignancy. Vertebral involvement quantification, neurological status, general health status and primary tumor histology are factors to set surgical planning and therapeutic targets. We evaluated the impact of general clinical and neurological status, histologic type and surgery in survival. Method : The study sample consisted of consecutive patients admitted from July 2010 to January 2013 for treatment. Results : Sixty eight patients were evaluated. 23 were female and 45 were male. Main primary neoplasic sites were: breast, prostate, lung\/pleura and linfoproliferative. Thirty three out of 68 received surgical treatment, 2 received percutaneous biopsy and 33 had nonsurgical treatment. Survival : Log Rank curves revealed no statistical significant difference according to histological type, surgical approach and Frankel Score. Karnofsky Score was statistically different. Conclusion : Histological type and clinical status were statistically associated with life expectancy in vertebral metastatic disease.<\/jats:p>","DOI":"10.1590\/0004-282x20150003","type":"journal-article","created":{"date-parts":[[2015,5,8]],"date-time":"2015-05-08T20:40:14Z","timestamp":1431117614000},"page":"330-335","source":"Crossref","is-referenced-by-count":14,"title":["Survival analysis in patients with metastatic spinal disease: the influence of surgery, histology, clinical and neurologic status"],"prefix":"10.1590","volume":"73","author":[{"given":"Matheus Fernandes de","family":"Oliveira","sequence":"first","affiliation":[{"name":"Hospital do Servidor P\u00fablico Estadual de S\u00e3o Paulo,  Brazil"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jose Marcus","family":"Rotta","sequence":"additional","affiliation":[{"name":"Hospital do Servidor P\u00fablico Estadual de S\u00e3o Paulo,  Brazil"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ricardo Vieira","family":"Botelho","sequence":"additional","affiliation":[{"name":"Hospital do Servidor P\u00fablico Estadual de S\u00e3o Paulo,  Brazil"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"530","reference":[{"issue":"8","key":"ref1","first-page":"632","article-title":"Management of spinal metastases, strategies and surgical indications","volume":"41","author":"Akbar M","year":"2012","journal-title":"Orthopade"},{"issue":"1","key":"ref2","first-page":"90","article-title":"The diagnosis and treatment of metastatic spinal tumor","volume":"177","author":"Bilsky MH","year":"1992","journal-title":"J Neurosurg"},{"issue":"7","key":"ref3","doi-asserted-by":"crossref","first-page":"286","DOI":"10.2174\/1874325001307010286","article-title":"Quantification of vertebral involvement in metastatic spinal disease","volume":"7","author":"Botelho RV","year":"2013","journal-title":"Open Orthop J"},{"issue":"6","key":"ref4","doi-asserted-by":"crossref","first-page":"523","DOI":"10.1007\/s005860000163","article-title":"Surgery in spinal metastasis without spinal cord compression: indications and strategy related to the risk of recurrence","volume":"9","author":"Chataigner H","year":"2000","journal-title":"Eur Spine J"},{"issue":"5","key":"ref5","doi-asserted-by":"crossref","first-page":"431","DOI":"10.1097\/BRS.0b013e318193a25b","article-title":"Selecting treatment for patients with malignant epidural spinal cord compression-does age matter?: results from a randomized clinical trial","volume":"34","author":"Chi JH","year":"2009","journal-title":"Spine. 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