{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,22]],"date-time":"2026-07-22T17:57:42Z","timestamp":1784743062896,"version":"3.55.0"},"reference-count":32,"publisher":"FapUNIFESP (SciELO)","issue":"1","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Arq. Neuro-Psiquiatr."],"abstract":"<jats:p>ABSTRACT Normal pressure hydrocephalus (NPH) is characterized by the triad of gait apraxia, dementia and urinary incontinence associated with ventriculomegaly and normal pressure of cerebrospinal fluid. Treatment is accomplished through the implantation of a ventricular shunt (VPS), however some complications are still frequent, like overdrainage due to siphon effect. This study analyses the performance of a valve with anti-siphon device (SPHERA\u00ae) in the treatment of patients with NPH and compares it with another group of patients with NPH who underwent the same procedure without anti-siphon mechanism (PS Medical\u00ae valve). 30 patients were consecutively enrolled in two groups with 15 patients each and followed clinically and radiologically for 1 year. Patients submitted to VPS with SPHERA\u00ae valve had the same clinical improvement as patients submitted to VPS with PS Medical\u00ae. However, complications and symptomatology due to overdrainage were significantly lower in SPHERA\u00ae group, suggesting it as a safe tool to treat NPH.<\/jats:p>","DOI":"10.1590\/0004-282x20150190","type":"journal-article","created":{"date-parts":[[2015,11,20]],"date-time":"2015-11-20T21:57:06Z","timestamp":1448056626000},"page":"55-61","source":"Crossref","is-referenced-by-count":11,"title":["Performance of the fixed pressure valve with antisiphon device SPHERA\u00ae in the treatment of normal pressure hydrocephalus and prevention of overdrainage"],"prefix":"10.1590","volume":"74","author":[{"given":"Renan M.","family":"Pereira","sequence":"first","affiliation":[{"name":"Universidade Anhembi Morumbi, Brazil"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mariane T.","family":"Suguimoto","sequence":"additional","affiliation":[{"name":"Universidade Anhembi Morumbi, Brazil"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Matheus F.","family":"Oliveira","sequence":"additional","affiliation":[{"name":"Hospital do Servidor P\u00fablico Estadual de S\u00e3o Paulo, Brazil"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Juliana B.","family":"Tornai","sequence":"additional","affiliation":[{"name":"Universidade de S\u00e3o Paulo, Brazil"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ricardo A.","family":"Amaral","sequence":"additional","affiliation":[{"name":"Universidade de S\u00e3o Paulo, Brazil"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Manoel Jacobsen","family":"Teixeira","sequence":"additional","affiliation":[{"name":"Universidade de S\u00e3o Paulo, Brazil; Universidade de S\u00e3o Paulo, Brazil"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Fernando Campos Gomes","family":"Pinto","sequence":"additional","affiliation":[{"name":"Universidade de S\u00e3o Paulo, Brazil"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"530","published-online":{"date-parts":[[2015,11,24]]},"reference":[{"key":"ref1","series-title":"Some observations on CSF pressure: hydrocephalic syndrome in adults with \u201cnormal\u201d CSF pressure","author":"Hakim S","year":"1964"},{"issue":"1","key":"ref2","doi-asserted-by":"crossref","first-page":"155","DOI":"10.1227\/01.NEU.0000370058.12120.0E","article-title":"Salom\u00f3n Hakim and the discovery of normal-pressure hydrocephalus","volume":"67","author":"Wallenstein MB","year":"2010","journal-title":"Neurosurgery"},{"issue":"4","key":"ref3","first-page":"307","article-title":"The special clinical problem of symptomatic hydrocephalus with normal cerebrospinal fluid pressure: observations on cerebrospinal fluid hydrodynamics","volume":"2","author":"Hakim S","year":"1965","journal-title":"J NeurolSci"},{"issue":"3 Suppl","key":"ref4","first-page":"S4","article-title":"Diagnosing idiopathic normal-pressure 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