{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,6,11]],"date-time":"2026-06-11T22:24:53Z","timestamp":1781216693307,"version":"3.54.1"},"reference-count":25,"publisher":"FapUNIFESP (SciELO)","issue":"10","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Arq. Neuro-Psiquiatr."],"published-print":{"date-parts":[[2016,10]]},"abstract":"<jats:p>ABSTRACT  Objective  To evaluate the effect of maintenance modified electroconvulsive therapy (MECT) on schizophrenic patients.  Methods  From June 2012 to June 2014, 62 patients with schizophrenia, who had recovered from a successful course of acute MECT, were recruited. Thirty-one patients received maintenance MECT and risperidone, as the experimental group. Another 31 patients were enrolled in the control group, and received risperidone only. The effects on cognitive functions, clinical symptoms and relapse rate were determined.  Results  Patients in the experimental group had a lower relapse rate and longer relapse-free survival time than the controls. Relative to the baseline evaluation, patients showed statistically significant improvement in verbal memory and visual memory. At the final assessment, the scores of verbal and visual memory were remarkably lower in the experimental group than the controls but there was no significant difference in other tests.  Conclusion  Maintenance MECT plus medication is superior to medication alone in preventing relapse and improving cognitive function.<\/jats:p>","DOI":"10.1590\/0004-282x20160130","type":"journal-article","created":{"date-parts":[[2016,10,15]],"date-time":"2016-10-15T17:36:39Z","timestamp":1476552999000},"page":"823-828","source":"Crossref","is-referenced-by-count":25,"title":["The maintenance of modified electroconvulsive therapy combined with risperidone is better than risperidone alone in preventing relapse of schizophrenia and improving cognitive function"],"prefix":"10.1590","volume":"74","author":[{"given":"Ying","family":"Yang","sequence":"first","affiliation":[{"name":"Shandong University,  China; Shandong Mental Health Center,  China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Xiaojing","family":"Cheng","sequence":"additional","affiliation":[{"name":"Shandong Mental Health Center,  China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Qingzhi","family":"Xu","sequence":"additional","affiliation":[{"name":"Shandong Mental Health Center,  China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Renjun","family":"Li","sequence":"additional","affiliation":[{"name":"Shandong Mental Health Center,  China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Zengxun","family":"Liu","sequence":"additional","affiliation":[{"name":"Shandong Mental Health Center,  China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Liping","family":"Wang","sequence":"additional","affiliation":[{"name":"Shandong Mental Health Center,  China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yanqing","family":"Zhang","sequence":"additional","affiliation":[{"name":"Qilu Children\u2019s Hospital of Shandong University,  China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Guoqiang","family":"Ren","sequence":"additional","affiliation":[{"name":"Shandong Mental Health Center,  China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jintong","family":"Liu","sequence":"additional","affiliation":[{"name":"Shandong University,  China; Shandong Mental Health Center,  China"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"530","reference":[{"key":"ref1","series-title":"The ECT handbook: the second report of the Royal College of Psychiatrists\u2019 Special Committee on ECT","author":"Freeman C","year":"1995"},{"key":"ref2","series-title":"Practice guideline for the treatment of patients with borderline personality disorder","year":"2001"},{"issue":"2","key":"ref3","first-page":"85","article-title":"The practice of ECT: recommendations for treatment, training and privileging American psychiatric association, task force on ECT","volume":"6","author":"Fink M","year":"1990","journal-title":"Convuls Ther"},{"key":"ref4","series-title":"The practice of ECT: recommendations for treatment, training and privileging: a task force report of the American Psychiatric Association","author":"Weiner R","year":"2001","edition":"2"},{"issue":"2","key":"ref5","doi-asserted-by":"crossref","first-page":"118","DOI":"10.1097\/00124509-200406000-00008","article-title":"Maintenance ECT for recurrent medication-refractory mania","volume":"20","author":"Tsao CI","year":"2004","journal-title":"J ECT"},{"issue":"6","key":"ref6","first-page":"657","article-title":"Maintenance ECT in treatment-resistant schizophrenia","volume":"83","author":"Chanpattana W","year":"2000","journal-title":"J Med Assoc Thai"},{"issue":"2","key":"ref7","doi-asserted-by":"crossref","first-page":"571","DOI":"10.1016\/j.pnpbp.2006.11.014","article-title":"Maintenance electroconvulsive therapy (ECT) for treatment-resistant disorganized schizophrenia","volume":"31","author":"Shimizu E","year":"2007","journal-title":"Progr Neuropsychopharmacol Biol Psychiatry"},{"issue":"1","key":"ref8","doi-asserted-by":"crossref","first-page":"132","DOI":"10.1046\/j.1440-1614.2001.0865e.x","article-title":"Maintenance electroconvulsive therapy in schizophrenia","volume":"35","author":"Stevens J","year":"2001","journal-title":"Aust N Z J Psychiatry"},{"issue":"3","key":"ref9","doi-asserted-by":"crossref","first-page":"280","DOI":"10.1016\/j.psychres.2008.10.012","article-title":"Maintenance electroconvulsive therapy: an alternative treatment for refractory schizophrenia and schizoaffective disorders","volume":"175","author":"L\u00e9vy-Rueff M","year":"2010","journal-title":"Psychiatry Res"},{"issue":"1","key":"ref10","doi-asserted-by":"crossref","first-page":"4","DOI":"10.1097\/00124509-200603000-00002","article-title":"ECT for treatment-resistant schizophrenia: a response from the far East to the UK. 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