{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,3,3]],"date-time":"2026-03-03T14:44:16Z","timestamp":1772549056611,"version":"3.50.1"},"reference-count":31,"publisher":"FapUNIFESP (SciELO)","issue":"7","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Arq. Neuro-Psiquiatr."],"abstract":"<jats:p>ABSTRACT Transcranial sonography (TCS) is an emerging ancillary examination for diagnosing Parkinson\u2019s disease (PD).  Objective  To evaluate TCS features in patients with PD and its mimics, and establish their accuracy in predicting the final clinical diagnosis after follow-up.  Methods  We retrospectively studied 85 patients with an initial clinical suspicion of PD, atypical parkinsonism or essential tremor, all of whom underwent TCS. Two specialists reviewed the follow-up clinical visit records and determined the final clinical diagnosis. The accuracy analysis of the TCS was determined using Bayesian statistical methods.  Results  The finding of substantia nigra hyperechogenicity (&gt; 20 mm2) showed high sensitivity (93.4%) and specificity (86.6%). The positive likelihood ratio showed 6.93-fold greater odds for diagnosing PD than an alternative condition when this finding was present.  Conclusions  This study revealed the practical usefulness of TCS in differentiating PD from its prevalent mimics when the clinical diagnosis was initially unclear.<\/jats:p>","DOI":"10.1590\/0004-282x20180067","type":"journal-article","created":{"date-parts":[[2018,7,27]],"date-time":"2018-07-27T18:59:44Z","timestamp":1532717984000},"page":"459-466","source":"Crossref","is-referenced-by-count":4,"title":["Is transcranial sonography useful for diagnosing Parkinson\u2019s disease in clinical practice?"],"prefix":"10.1590","volume":"76","author":[{"given":"Talyta Cortez","family":"Grippe","sequence":"first","affiliation":[{"name":"Universidade de Bras\u00edlia,  Brasil; Hospital de Base do Distrito Federal,  Brasil"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Nasser","family":"Allam","sequence":"additional","affiliation":[{"name":"Hospital de Base do Distrito Federal,  Brasil"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Pedro Renato de Paula","family":"Brand\u00e3o","sequence":"additional","affiliation":[{"name":"Hospital de Base do Distrito Federal,  Brasil; C\u00e2mara dos Deputados,  Brasil"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Danilo Assis","family":"Pereira","sequence":"additional","affiliation":[{"name":"Instituto Brasileiro de Neuropsicologia e Ci\u00eancias Cognitivas,  Brasil"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Francisco Eduardo Costa","family":"Cardoso","sequence":"additional","affiliation":[{"name":"Universidade Federal de Minas Gerais,  Brasil"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ana Carolina Rodrigues","family":"Aguilar","sequence":"additional","affiliation":[{"name":"Hospital de Base do Distrito Federal,  Brasil"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Iruena Moraes","family":"Kessler","sequence":"additional","affiliation":[{"name":"Universidade de Bras\u00edlia,  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