{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,11]],"date-time":"2026-09-11T20:08:47Z","timestamp":1789157327564,"version":"build-2803163510"},"reference-count":35,"publisher":"FapUNIFESP (SciELO)","issue":"3","license":[{"start":{"date-parts":[[2019,3,1]],"date-time":"2019-03-01T00:00:00Z","timestamp":1551398400000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"},{"start":{"date-parts":[[2019,3,1]],"date-time":"2019-03-01T00:00:00Z","timestamp":1551398400000},"content-version":"am","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"},{"start":{"date-parts":[[2019,3,1]],"date-time":"2019-03-01T00:00:00Z","timestamp":1551398400000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Arq. Neuro-Psiquiatr."],"abstract":"<jats:p>ABSTRACT Tension-type headaches (TTH) and irritable bowel syndrome (IBS) are comorbid diseases affecting, especially, women. One of the underlying mechanisms for both is autonomic dysfunction in the brain-gut axis. We aimed to evaluate the factors accompanying TTH and their relation to functional gastrointestinal disorders. Methods: Women diagnosed with TTH were questioned about headache pattern and severity, and accompanying factors, as well as being screened for IBS according to the Rome III criteria. The participants were divided into two groups: constipation-dominant IBS (IBS-C) group and \u201cothers\u201d, with a total of 115 individuals included in the study. Results: Of the 115 patients; 48 (41.8%) of the women had IBS-C criteria while 67 (58.2%) described mixed-type IBS or diarrhea-dominant IBS. There were no significant differences in terms of mean age (p = 0.290), body mass index (p = 0.212), visual analog scale (p = 0.965), duration of attacks (p = 0.692), and episodic\/chronic type (p = 0.553). Osmophobia was seen in 43.5%; phonophobia in 68.7%, and photophobia in 47.0% of the patients, and only osmophobia was significantly associated in women in the IBS-C group (p = 0.001). Conclusion: In female patients with TTH, a higher level of constipation was detected. The relationship of these two diseases suggests that they may share common mechanisms. This is the first study showing the relationship of osmophobia with constipation.<\/jats:p>","DOI":"10.1590\/0004-282x20190015","type":"journal-article","created":{"date-parts":[[2019,4,3]],"date-time":"2019-04-03T23:35:58Z","timestamp":1554334558000},"page":"161-165","source":"Crossref","is-referenced-by-count":5,"title":["Constipation is associated with tension type headache in women"],"prefix":"10.1590","volume":"77","author":[{"given":"Zeynep Tugba","family":"Ozan","sequence":"first","affiliation":[{"name":"Bozok University, Turkey"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Nermin","family":"Tanik","sequence":"additional","affiliation":[{"name":"Bozok University, Turkey"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-2441-0624","authenticated-orcid":false,"given":"Levent Ertugrul","family":"Inan","sequence":"additional","affiliation":[{"name":"Bozok University, Turkey"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"530","published-online":{"date-parts":[[2019,3]]},"reference":[{"issue":"1","key":"ref1","doi-asserted-by":"crossref","first-page":"58","DOI":"10.1186\/s10194-015-0544-2","article-title":"Headache disorders are third cause of disability worldwide","volume":"16","author":"Steiner TJ","year":"2015","journal-title":"J Headache Pain"},{"issue":"11","key":"ref2","doi-asserted-by":"crossref","first-page":"1274","DOI":"10.3109\/00365521.2012.688215","article-title":"Prevalence, comorbidity, and risk factors for functional bowel symptoms: a population-based survey in Northern Norway","volume":"47","author":"Breckan RK","year":"2012","journal-title":"Scand J Gastroenterol"},{"issue":"3","key":"ref3","doi-asserted-by":"crossref","first-page":"446","DOI":"10.1007\/s10620-006-3153-8","article-title":"Prevalence, sociodemography, and quality of life of older versus younger patients with irritable bowel syndrome: a population-based study","volume":"51","author":"Minocha A","year":"2006","journal-title":"Dig Dis Sci"},{"issue":"2","key":"ref4","first-page":"144","article-title":"Comorbidity of headache and gastrointestinal complaints. 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