{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,2,22]],"date-time":"2026-02-22T22:22:18Z","timestamp":1771798938153,"version":"3.50.1"},"reference-count":37,"publisher":"FapUNIFESP (SciELO)","issue":"3","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Rev. Bras. Enferm."],"published-print":{"date-parts":[[2017,6]]},"abstract":"<jats:p>ABSTRACT  Objective: To identify scientific evidence regarding the influence of hormonal contraceptive use and the occurrence of stroke.  Method: Integrative review of the literature, through database search using the descriptors \"contraceptive agents\", \"contraceptive devices\", \"contraceptives, Oral\" and \"Stroke\". Original studies in Portuguese, Spanish and English, published in full and available online were included. Studies that did not answer our guiding questions and duplicated studies were excluded.  Results: Women using combined oral contraceptives have higher risk of stroke, even with a lower hormonal dosage and different types of progestogen, regardless of the duration of use. The use of contraceptives associated with smoking, hypertension, migraine, hypercholesterolemia, obesity and sedentary lifestyle increases the chance of stroke. Contraceptive patch and vaginal ring are associated to increased risk.  Conclusion: Use of combined hormonal contraceptives, except for the injectable and the transdermal ones, increases the chance of occurrence of the event. Progestogen-only contraceptives were considered safe.<\/jats:p>","DOI":"10.1590\/0034-7167-2016-0056","type":"journal-article","created":{"date-parts":[[2017,5,28]],"date-time":"2017-05-28T15:22:07Z","timestamp":1495984927000},"page":"647-655","source":"Crossref","is-referenced-by-count":21,"title":["Influence of hormonal contraceptives and the occurrence of stroke: integrative review"],"prefix":"10.1590","volume":"70","author":[{"given":"Adman C\u00e2mara Soares","family":"Lima","sequence":"first","affiliation":[{"name":"Universidade Federal do Cear\u00e1,  Brazil"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Larissa Castelo Guedes","family":"Martins","sequence":"additional","affiliation":[{"name":"Universidade Federal do Cear\u00e1,  Brazil"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Marcos Ven\u00edcios de Oliveira","family":"Lopes","sequence":"additional","affiliation":[{"name":"Universidade Federal do Cear\u00e1,  Brazil"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Thelma Leite de","family":"Ara\u00fajo","sequence":"additional","affiliation":[{"name":"Universidade Federal do Cear\u00e1,  Brazil"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Francisca Elis\u00e2ngela Teixeira","family":"Lima","sequence":"additional","affiliation":[{"name":"Universidade Federal do Cear\u00e1,  Brazil"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Priscila de Souza","family":"Aquino","sequence":"additional","affiliation":[{"name":"Universidade Federal do Cear\u00e1,  Brazil"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Escol\u00e1stica Rejane Ferreira","family":"Moura","sequence":"additional","affiliation":[{"name":"Universidade Federal do Cear\u00e1,  Brazil"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"530","reference":[{"issue":"4","key":"ref1","doi-asserted-by":"crossref","first-page":"e81","DOI":"10.1590\/S0066-782X2011005000022","article-title":"Contracep\u00e7\u00e3o Hormonal e Sistema Cardiovascular","volume":"96","author":"Brito MB","year":"2011","journal-title":"Arq Bras Cardiol"},{"key":"ref2","first-page":"120","article-title":"Risk factors for venous and arterial thrombosis","volume":"9","author":"Previtali E","year":"2011","journal-title":"Blood Transfus"},{"key":"ref3","doi-asserted-by":"crossref","first-page":"35","DOI":"10.1016\/j.contraception.2011.08.017","article-title":"A combined oral contraceptive containing drospirenone changes neither endothelial function nor hemodynamic parameters in healthy Young women: a prospective clinical trial","volume":"86","author":"Giribela CRG","year":"2012","journal-title":"Contraception"},{"key":"ref4","series-title":"Stroke, Cerebrovascular accident","year":"2011"},{"key":"ref5","series-title":"Criterios m\u00e9dicos de elegibilidad para el uso de anticonceptivos","year":"2012","edition":"4\u00aa ed"},{"key":"ref6","series-title":"Sa\u00fade sexual e sa\u00fade reprodutiva","year":"2013"},{"issue":"24","key":"ref7","doi-asserted-by":"crossref","first-page":"2257","DOI":"10.1056\/NEJMoa1111840","article-title":"Thrombotic stroke and myocardial infarction with hormonal contraception","volume":"366","author":"Lidegaard O","year":"2012","journal-title":"N Engl J Med"},{"issue":"8","key":"ref8","doi-asserted-by":"crossref","DOI":"10.1002\/14651858.CD011054.pub2","article-title":"Combined oral contraceptives: the risk of myocardial infarction and ischemic stroke","volume":"27","author":"Roach RE","year":"2015","journal-title":"Cochrane Database Syst Rev"},{"issue":"2","key":"ref9","doi-asserted-by":"crossref","first-page":"380","DOI":"10.1097\/AOG.0b013e3182994c43","article-title":"Risk of acute thromboembolic events with oral contraceptive use","volume":"122","author":"Peragallo Urrutia R","year":"2013","journal-title":"Obstet Gynecol"},{"issue":"5","key":"ref10","doi-asserted-by":"crossref","first-page":"546","DOI":"10.1111\/j.1365-2648.2005.03621.x","article-title":"The integrative review: updated methodology","volume":"52","author":"Whittemore R","year":"2005","journal-title":"J Adv Nurs"},{"key":"ref11","series-title":"Melnyk BM, Fineout-Overholt E. 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