{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,12]],"date-time":"2026-10-12T14:04:55Z","timestamp":1791813895184,"version":"4.3.4"},"reference-count":32,"publisher":"FapUNIFESP (SciELO)","issue":"3","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Mem. Inst. Oswaldo Cruz"],"DOI":"10.1590\/0074-02760150307","type":"journal-article","created":{"date-parts":[[2016,2,17]],"date-time":"2016-02-17T23:40:12Z","timestamp":1455752412000},"page":"147-154","source":"Crossref","is-referenced-by-count":10,"title":["In vivo antileishmanial activity and chemical profile of polar extract from Selaginella sellowii"],"prefix":"10.1590","volume":"111","author":[{"given":"Dayane Priscilla de Souza","family":"Queiroz","sequence":"first","affiliation":[{"name":"Universidade Federal de Mato Grosso do Sul, Brasil"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Carlos Alexandre","family":"Carollo","sequence":"additional","affiliation":[{"name":"Universidade Federal de Mato Grosso do Sul, Brasil"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"M\u00f4nica Cristina Toffoli","family":"Kadri","sequence":"additional","affiliation":[{"name":"Universidade Federal de Mato Grosso do Sul, Brasil"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yasmin Silva","family":"Rizk","sequence":"additional","affiliation":[{"name":"Universidade Federal de Mato Grosso do Sul, Brasil"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Vanessa Carneiro Pereira de","family":"Araujo","sequence":"additional","affiliation":[{"name":"Universidade Federal de Mato Grosso do Sul, Brasil"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Paulo Eduardo de Oliveira","family":"Monteiro","sequence":"additional","affiliation":[{"name":"Universidade Federal de Mato Grosso do Sul, Brasil"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Patrik Oening","family":"Rodrigues","sequence":"additional","affiliation":[{"name":"Universidade Federal de Mato Grosso do Sul, Brasil"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Elisa Teruya","family":"Oshiro","sequence":"additional","affiliation":[{"name":"Universidade Federal de Mato Grosso do Sul, Brasil"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Maria de F\u00e1tima Cepa","family":"Matos","sequence":"additional","affiliation":[{"name":"Universidade Federal de Mato Grosso do Sul, Brasil"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Carla Cardozo Pinto de","family":"Arruda","sequence":"additional","affiliation":[{"name":"Universidade Federal de Mato Grosso do Sul, Brasil"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"530","published-online":{"date-parts":[[2016,2,19]]},"reference":[{"key":"ref1","doi-asserted-by":"crossref","first-page":"500","DOI":"10.1016\/j.fitote.2011.12.025","article-title":"Antiparasitic antioxidant phenylpropanoids and iridoid glycosides from Tecoma mollis","volume":"83","author":"Abdel-Mageed WM","year":"2012","journal-title":"Fitoterapia"},{"key":"ref2","doi-asserted-by":"crossref","first-page":"712","DOI":"10.5740\/jaoacint.11-029","article-title":"Determination of biflavonoids in four Mexican species of Selaginella by HPLC","volume":"96","author":"Aguilar MI","year":"2013","journal-title":"J AOAC Int"},{"key":"ref3","doi-asserted-by":"crossref","first-page":"6994","DOI":"10.1021\/jf8010432","article-title":"Biflavonoids isolated from Selaginella lepidophylla inhibit photosynthesis in spinach chloroplasts","volume":"56","author":"Aguilar MI","year":"2008","journal-title":"J Agric Food Chem"},{"key":"ref4","doi-asserted-by":"crossref","first-page":"643","DOI":"10.1016\/j.biopha.2009.02.004","article-title":"Inhibitory activity of limonene against Leishmania parasites in vitro and in vivo","volume":"63","author":"Arruda DC","year":"2009","journal-title":"Biomed Pharmacother"},{"key":"ref5","doi-asserted-by":"crossref","first-page":"2407","DOI":"10.4049\/jimmunol.141.7.2407","article-title":"Release of reactive nitrogen intermediates and reactive oxygen intermediates from mouse peritoneal macrophages: comparison of activating cytokines and evidence for independent production","volume":"141","author":"Ding AH","year":"1988","journal-title":"J Immunol"},{"key":"ref6","doi-asserted-by":"crossref","first-page":"196","DOI":"10.1016\/j.phytochem.2014.10.005","article-title":"Retention time prediction for dereplication of natural products (CxHyOz) in LC-MS metabolite profiling","volume":"108","author":"Eugster PJ","year":"2014","journal-title":"Phytochemistry"},{"key":"ref7","article-title":"In vitro and in vivo antileishmanial effects of Pistacia khinjuk against Leishmania tropica and Leishmania major","author":"Ezatpour B","year":"2015","journal-title":"eCAM"},{"key":"ref8","doi-asserted-by":"crossref","first-page":"2447","DOI":"10.1128\/AAC.40.11.2447","article-title":"In vivo efficacy of oral and intralesional administration of 2-substituted quinolines in experimental treatment of new world cutaneous leishmaniasis caused by Leishmania amazonensis","volume":"40","author":"Fournet A","year":"1996","journal-title":"Antimicrob Agents Chemother"},{"key":"ref9","doi-asserted-by":"crossref","first-page":"1215","DOI":"10.2174\/1568026023393011","article-title":"Natural products as trypanocidal, antileishmanial, and antimalarial drugs","volume":"2","author":"Fournet A","year":"2002","journal-title":"Curr Top Med Chem"},{"key":"ref10","doi-asserted-by":"crossref","first-page":"575","DOI":"10.1590\/S0102-695X2010000400017","article-title":"Comparative profiles of Achyrocline alata (Kunth) DC. and A. satureioides (Lam.) DC., Asteraceae, applying HPLC-DAD-MS","volume":"20","author":"Grassi-Zampieron R","year":"2010","journal-title":"Rev Bras Farmacogn"},{"key":"ref11","first-page":"1","article-title":"Antileshmanial drug testing: appraisal on existing techniques","volume":"16","author":"Gupta S","year":"1992","journal-title":"Indian J Parasitol"},{"key":"ref12","doi-asserted-by":"crossref","first-page":"1927","DOI":"10.1016\/j.phytochem.2005.06.019","article-title":"Phenylpropanoid glucosides from leaves of Coussarea hydrangeifolia (Rubiaceae)","volume":"66","author":"Hamerski L","year":"2005","journal-title":"Phytochemistry"},{"key":"ref13","doi-asserted-by":"crossref","first-page":"171","DOI":"10.1016\/j.phytol.2008.09.003","article-title":"Antiplasmodial and leishmanicidal activity of biflavonoids from Indian Selaginella bryopteris","volume":"1","author":"Kunert O","year":"2008","journal-title":"Phytochem Lett"},{"key":"ref14","doi-asserted-by":"crossref","first-page":"732","DOI":"10.1016\/j.bmc.2007.10.036","article-title":"Biflavonoids isolated from Selaginella tamariscina regulate the expression of matrix metalloproteinase in human skin fibroblasts","volume":"16","author":"Lee CW","year":"2008","journal-title":"Bioorg Med Chem"},{"key":"ref15","doi-asserted-by":"crossref","first-page":"168","DOI":"10.1055\/s-2006-959443","article-title":"Phenolic constituents of Selaginella doederleinii","volume":"60","author":"Lin RC","year":"1994","journal-title":"Planta Med"},{"key":"ref16","doi-asserted-by":"crossref","first-page":"309","DOI":"10.1016\/j.jaad.2009.06.088","article-title":"New World cutaneous leishmaniasis: updated review of current and future diagnosis and treatment","volume":"63","author":"Mitropoulos P","year":"2010","journal-title":"J Am Acad Dermatol"},{"key":"ref17","doi-asserted-by":"crossref","first-page":"313","DOI":"10.1016\/j.jep.2007.10.009","article-title":"Eficacy of the intralesional treatment with Chenopodium ambrosioides in the murine infection by Leishmania amazonensis","volume":"115","author":"Patr\u00edcio FJ","year":"2008","journal-title":"J Ethnopharmacol"},{"key":"ref18","doi-asserted-by":"crossref","first-page":"157","DOI":"10.1016\/j.jinf.2004.09.009","article-title":"Immunomodulatory effect of Canova medication on experimental Leishmania amazonensis infection","volume":"51","author":"Pereira WKV","year":"2005","journal-title":"J Infect"},{"key":"ref19","doi-asserted-by":"crossref","first-page":"487","DOI":"10.1007\/s00436-008-0970-z","article-title":"In vitro and in vivo antileishmanial activities of a Brazilian green propolis extract","volume":"103","author":"Pontin K","year":"2008","journal-title":"Parasitol Res"},{"key":"ref20","doi-asserted-by":"crossref","first-page":"581","DOI":"10.1016\/S1473-3099(07)70209-8","article-title":"Cutaneous leishmaniasis","volume":"7","author":"Reithinger R","year":"2007","journal-title":"Lancet Infect Dis"},{"key":"ref21","doi-asserted-by":"crossref","first-page":"1050","DOI":"10.1590\/0074-0276140312","article-title":"In vitro activity of the hydroethanolic extract and biflavonoids isolated from Selaginella sellowii on Leishmania (Leishmania) amazonensis","volume":"109","author":"Rizk YS","year":"2014","journal-title":"Mem Inst Oswaldo Cruz"},{"key":"ref22","doi-asserted-by":"crossref","first-page":"469","DOI":"10.1007\/BF02492011","article-title":"HPLC quantification of flavonoids and biflavonoids in Cupressaceae leaves","volume":"56","author":"Romani A","year":"2002","journal-title":"Chromatographia"},{"key":"ref23","doi-asserted-by":"crossref","first-page":"908","DOI":"10.4049\/jimmunol.138.3.908","article-title":"An analysis of T-cell responsiveness in Indian kala-azar","volume":"138","author":"Sacks DL","year":"1987","journal-title":"J Immunol"},{"key":"ref24","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1007\/s00436-008-0943-2","article-title":"Leishmaniasis treatment - a challenge that remains: a review","volume":"103","author":"Santos DO","year":"2008","journal-title":"Parasitol Res"},{"key":"ref25","doi-asserted-by":"crossref","first-page":"5","DOI":"10.1600\/036364413X661935","article-title":"Taxonomic revision of Selaginella subg","volume":"38","author":"Schulz C","year":"2013","journal-title":"Ericetorum Syst Bot"},{"key":"ref26","doi-asserted-by":"crossref","first-page":"285","DOI":"10.1002\/ddr.10324","article-title":"Antileishmanial action of a plant Tephrosia pupurea Linn, extracts and its fractions against experimental visceral leishmaniasis","volume":"60","author":"Sharma P","year":"2003","journal-title":"Drug Dev Res"},{"key":"ref27","doi-asserted-by":"crossref","first-page":"129","DOI":"10.1016\/0031-9422(95)00212-P","article-title":"Cytotoxic biflavonoids from Selaginell willdenowii","volume":"40","author":"Silva GL","year":"1995","journal-title":"Phytochemistry"},{"key":"ref28","doi-asserted-by":"crossref","first-page":"382","DOI":"10.1021\/np960608e","article-title":"Selective cytotoxicity of ginkgetin from Selaginella moellendorffii","volume":"60","author":"Sun C-M","year":"1997","journal-title":"J Nat Prod"},{"key":"ref29","doi-asserted-by":"crossref","first-page":"9135","DOI":"10.1021\/ac901723y","article-title":"Modeling the retention of neutral compounds in gradient elution RP-HPLC by means of polarity parameter models","volume":"81","author":"Tellez A","year":"2009","journal-title":"Anal Chem"},{"key":"ref30","doi-asserted-by":"crossref","first-page":"545","DOI":"10.1111\/j.1365-3024.1985.tb00098.x","article-title":"A limiting dilution assay for quantifying Leishmania major in tissues of infected mice","volume":"7","author":"Titus RG","year":"1985","journal-title":"Parasite Immunol"},{"key":"ref31","doi-asserted-by":"crossref","first-page":"176","DOI":"10.1016\/j.phymed.2004.10.008","article-title":"Comparative antiplasmodial, leishmanicidal, and antitrypanosomal activities of several biflavonoids","volume":"13","author":"Weniger B","year":"2006","journal-title":"Phytomedicine"},{"key":"ref32","doi-asserted-by":"crossref","first-page":"1707","DOI":"10.1016\/j.intimp.2008.07.016","article-title":"Immunopotentiation of caffeoyl glycoside from Picrorhiza scrophulariiflora on activation and cytokines secretion of immunocyte in vitro","volume":"8","author":"Zeng S","year":"2008","journal-title":"Int Immunopharmacol"}],"container-title":["Mem\u00f3rias do Instituto Oswaldo Cruz"],"original-title":[],"link":[{"URL":"http:\/\/www.scielo.br\/pdf\/mioc\/v111n3\/0074-0276-mioc-0074-02760150307.pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,8,16]],"date-time":"2023-08-16T22:32:32Z","timestamp":1692225152000},"score":1,"resource":{"primary":{"URL":"http:\/\/www.scielo.br\/scielo.php?script=sci_arttext&pid=S0074-02762016000300147&lng=en&tlng=en"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2016,2,19]]},"references-count":32,"journal-issue":{"issue":"3","published-online":{"date-parts":[[2016,3]]}},"alternative-id":["S0074-02762016000300147"],"URL":"https:\/\/doi.org\/10.1590\/0074-02760150307","relation":{},"ISSN":["1678-8060","0074-0276"],"issn-type":[{"value":"1678-8060","type":"electronic"},{"value":"0074-0276","type":"print"}],"subject":[],"published":{"date-parts":[[2016,2,19]]}}}