{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,19]],"date-time":"2026-09-19T11:54:31Z","timestamp":1789818871245,"version":"4.0.1"},"reference-count":30,"publisher":"FapUNIFESP (SciELO)","issue":"8","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Mem. Inst. Oswaldo Cruz"],"published-print":{"date-parts":[[2017,8]]},"DOI":"10.1590\/0074-02760160529","type":"journal-article","created":{"date-parts":[[2017,7,29]],"date-time":"2017-07-29T19:15:35Z","timestamp":1501355735000},"page":"561-568","source":"Crossref","is-referenced-by-count":14,"title":["Protection mediated by chemokine CXCL10 in BALB\/c mice infected by Leishmania infantum"],"prefix":"10.1590","volume":"112","author":[{"given":"Webertty Mayk Eufr\u00e1sio","family":"Figueiredo","sequence":"first","affiliation":[{"name":"Universidade Federal do Cear\u00e1,  Brasil"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sayonara de Melo","family":"Viana","sequence":"additional","affiliation":[{"name":"Universidade Federal do Cear\u00e1,  Brasil"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Dorotheia Teixeira","family":"Alves","sequence":"additional","affiliation":[{"name":"Universidade Federal do Cear\u00e1,  Brasil"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Priscila Valera","family":"Guerra","sequence":"additional","affiliation":[{"name":"Universidade Federal do Cear\u00e1,  Brasil"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Zirlane Castelo Branco","family":"Co\u00ealho","sequence":"additional","affiliation":[{"name":"Universidade Federal do Cear\u00e1,  Brasil"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Helene Santos","family":"Barbosa","sequence":"additional","affiliation":[{"name":"Funda\u00e7\u00e3o Oswaldo Cruz-Fiocruz,  Brasil"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Maria Jania","family":"Teixeira","sequence":"additional","affiliation":[{"name":"Universidade Federal do Cear\u00e1,  Brasil"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"530","reference":[{"issue":"10","key":"ref1","doi-asserted-by":"crossref","first-page":"2885","DOI":"10.1002\/eji.200425318","article-title":"A unique pattern of up- and downregulation of chemokine receptor CXCR3 on inflammation-inducing Th1 cells","volume":"34","author":"Chen J","year":"2004","journal-title":"Eur J Immunol"},{"issue":"8","key":"ref2","doi-asserted-by":"crossref","first-page":"1300","DOI":"10.1086\/605895","article-title":"CXC chemokine-mediated protection against visceral leishmaniasis: involvement of the proinflammatory response","volume":"200","author":"Gupta G","year":"2009","journal-title":"J Infect Dis"},{"issue":"4","key":"ref3","doi-asserted-by":"crossref","first-page":"241","DOI":"10.1007\/s00430-011-0197-y","article-title":"Treatment with IP-10 induces host-protective immune response by regulating the T regulatory cell functioning in Leishmania donovani-infected mice","volume":"200","author":"Gupta G","year":"2011","journal-title":"Med Microbiol Immunol"},{"issue":"3-4","key":"ref4","doi-asserted-by":"crossref","first-page":"247","DOI":"10.1016\/j.vetimm.2005.03.001","article-title":"Lymphocytes of dogs immunized with purified excreted-secreted antigens of Leishmania infantum co-incubated with Leishmania infected macrophages produce IFN-gamma resulting in nitric oxide-mediated amastigotes apoptosis","volume":"106","author":"Holzm\u00fcller P","year":"2005","journal-title":"Vet Immunol Immunopathol"},{"key":"ref5","doi-asserted-by":"crossref","first-page":"239","DOI":"10.1111\/j.0105-2896.2004.00188.x","article-title":"The immunopathology of experimental visceral leishmaniasis","volume":"201","author":"Kaye PM","year":"2004","journal-title":"Immunol Rev"},{"issue":"5","key":"ref6","doi-asserted-by":"crossref","first-page":"188","DOI":"10.1016\/S0169-4758(00)01637-9","article-title":"The strange case of Leishmania chagasi","volume":"16","author":"Maur\u00edcio IL","year":"2000","journal-title":"Parasitol Today"},{"issue":"9","key":"ref7","doi-asserted-by":"crossref","first-page":"557","DOI":"10.1016\/S1473-3099(06)70577-1","article-title":"The two faces of interleukin 10 in human infectious diseases","volume":"6","author":"Mege JL","year":"2006","journal-title":"Lancet Infect Dis"},{"issue":"3","key":"ref8","doi-asserted-by":"crossref","first-page":"1912","DOI":"10.4049\/jimmunol.166.3.1912","article-title":"The hamster as a model of human visceral leishmaniasis: progressive disease and impaired generation of nitric oxide in the face of a prominent Th1-like cytokine response","volume":"166","author":"Melby PC","year":"2001","journal-title":"J Immunol"},{"issue":"6","key":"ref9","doi-asserted-by":"crossref","first-page":"1702","DOI":"10.1002\/eji.200425885","article-title":"CXCR3 is required for migration to dermal inflammation by normal and in vivo activated T cells: differential requirements by CD4 and CD8 memory subsets","volume":"35","author":"Mohan K","year":"2005","journal-title":"Eur J Immunol"},{"issue":"12","key":"ref10","first-page":"7302","article-title":"Differences between IL-4- and IL-4 receptor alpha-deficient mice in chronic leishmaniasis reveal a protective role for IL-13 receptor signaling","volume":"162","author":"Mohrs M","year":"1999","journal-title":"J Immunol"},{"issue":"1-2","key":"ref11","doi-asserted-by":"crossref","first-page":"73","DOI":"10.1007\/s004300100084","article-title":"Chemokines, natural killer cells and granulocytes in the early course of Leishmania major infection in mice","volume":"190","author":"M\u00fcller K","year":"2001","journal-title":"Med Microbiol Immunol"},{"issue":"9496","key":"ref12","doi-asserted-by":"crossref","first-page":"1561","DOI":"10.1016\/S0140-6736(05)67629-5","article-title":"Advances in leishmaniasis","volume":"366","author":"Murray HW","year":"2005","journal-title":"Lancet"},{"issue":"11","key":"ref13","doi-asserted-by":"crossref","first-page":"6284","DOI":"10.1128\/IAI.70.11.6284-6293.2002","article-title":"Interleukin-10 (IL-10) in experimental visceral leishmaniasis and IL-10 receptor blockade as immunotherapy","volume":"70","author":"Murray HW","year":"2002","journal-title":"Infect Immun"},{"issue":"1","key":"ref14","first-page":"e00824","article-title":"Gamma interferon-regulated chemokines in Leishmania donovani infection in the liver","volume":"85","author":"Murray HW","year":"2016","journal-title":"Infect Immun"},{"issue":"3","key":"ref15","doi-asserted-by":"crossref","first-page":"458","DOI":"10.1086\/376510","article-title":"Determinants of response to interleukin-10 receptor blockade immunotherapy in experimental visceral leishmaniasis","volume":"188","author":"Murray HW","year":"2003","journal-title":"J Infect Dis"},{"issue":"5","key":"ref16","doi-asserted-by":"crossref","first-page":"249","DOI":"10.1046\/j.1365-2613.2001.00199.x","article-title":"Tissue granuloma structure-function in experimental visceral leishmaniasis","volume":"82","author":"Murray HW","year":"2001","journal-title":"Int J Exp Pathol"},{"key":"ref17","doi-asserted-by":"crossref","first-page":"39","DOI":"10.1186\/1297-9716-42-39","article-title":"Mechanisms of resistance and susceptibility to experimental visceral leishmaniosis: BALB\/c mouse versus syrian hamster model","volume":"42","author":"Nieto A","year":"2011","journal-title":"Vet Res"},{"issue":"972","key":"ref18","doi-asserted-by":"crossref","first-page":"649","DOI":"10.1136\/pgmj.2006.047340","article-title":"Leishmaniasis","volume":"82","author":"Piscopo TV","year":"2006","journal-title":"Postgrad Med J"},{"issue":"6","key":"ref19","doi-asserted-by":"crossref","first-page":"1914","DOI":"10.1172\/JCI114654","article-title":"Modulation of in vitro monocyte cytokine responses to Leishmania donovani. Interferon-gamma prevents parasite-induced inhibition of interleukin 1 production and primes monocytes to respond to Leishmania by producing both tumor necrosis factor-alpha and interleukin 1","volume":"85","author":"Reiner NE","year":"1990","journal-title":"J Clin Invest"},{"issue":"11","key":"ref20","doi-asserted-by":"crossref","first-page":"3111","DOI":"10.1002\/1521-4141(200011)30:11<3111::AID-IMMU3111>3.0.CO;2-O","article-title":"Monocyte chemotactic protein-1 stimulates the killing of Leishmania major by human monocytes, acts synergistically with IFN-gamma and is antagonized by IL-4","volume":"30","author":"Ritter U","year":"2000","journal-title":"Eur J Immunol"},{"key":"ref21","doi-asserted-by":"crossref","first-page":"296","DOI":"10.3389\/fimmu.2014.00296","article-title":"Immunotherapy and targeted therapies in treatment of visceral leishmaniasis: current status and future prospects","volume":"5","author":"Singh OP","year":"2014","journal-title":"Front Immunol"},{"key":"ref22","doi-asserted-by":"crossref","DOI":"10.1186\/1471-2334-10-209","article-title":"Resistance of Leishmania (Viannia) braziliensis to nitric oxide: correlation with antimony therapy and TNF-alpha production","volume":"10","author":"Souza AS","year":"2010","journal-title":"BMC Infect Dis"},{"issue":"8","key":"ref23","doi-asserted-by":"crossref","first-page":"4804","DOI":"10.1128\/IAI.71.8.4804-4807.2003","article-title":"Both interleukin-4 (IL-4) and IL-4 receptor alpha signaling contribute to the development of hepatic granulomas with optimal antileishmanial activity","volume":"71","author":"St\u00e4ger S","year":"2003","journal-title":"Infect Immun"},{"issue":"2","key":"ref24","doi-asserted-by":"crossref","first-page":"138","DOI":"10.1038\/sj.icb7100011","article-title":"Balancing immunity and pathology in visceral leishmaniasis","volume":"85","author":"Stanley AC","year":"2007","journal-title":"Immunol Cell Biol"},{"issue":"1","key":"ref25","doi-asserted-by":"crossref","first-page":"32","DOI":"10.1016\/j.pt.2005.11.010","article-title":"Chemokines in host-parasite interactions in leishmaniasis","volume":"22","author":"Teixeira MJ","year":"2006","journal-title":"Trends Parasitol"},{"issue":"5","key":"ref26","doi-asserted-by":"crossref","first-page":"545","DOI":"10.1111\/j.1365-3024.1985.tb00098.x","article-title":"A limiting dilution assay for quantifying Leishmania major in tissues of infected mice","volume":"7","author":"Titus RG","year":"1985","journal-title":"Parasite Immunol"},{"issue":"2","key":"ref27","doi-asserted-by":"crossref","first-page":"337","DOI":"10.1016\/j.freeradbiomed.2011.05.011","article-title":"Leishmania-macrophage interactions: insights into the redox biology","volume":"51","author":"Van Assche T","year":"2011","journal-title":"Free Radic Biol Med"},{"issue":"12","key":"ref28","doi-asserted-by":"crossref","first-page":"6769","DOI":"10.1128\/IAI.01073-06","article-title":"CXCL10\/gamma interferon-inducible protein 10-mediated protection against Leishmania amazonensis infection in mice","volume":"74","author":"V\u00e1squez RE","year":"2006","journal-title":"Infect Immun"},{"issue":"4","key":"ref29","doi-asserted-by":"crossref","first-page":"860","DOI":"10.1002\/eji.1830270409","article-title":"Interleukin-10 and interleukin-4 inhibit intracellular killing of Leishmania infantum and Leishmania major by human macrophages by decreasing nitric oxide generation","volume":"27","author":"Vouldoukis I","year":"1997","journal-title":"Eur J Immunol"},{"issue":"4","key":"ref30","doi-asserted-by":"crossref","first-page":"147","DOI":"10.1016\/j.micpath.2004.11.002","article-title":"Immunopathogenesis of infection with the visceralizing Leishmania species","volume":"38","author":"Wilson ME","year":"2005","journal-title":"Microb Pathog"}],"container-title":["Mem\u00f3rias do Instituto Oswaldo Cruz"],"original-title":[],"link":[{"URL":"http:\/\/www.scielo.br\/pdf\/mioc\/v112n8\/0074-0276-mioc-112-8-0561.pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2017,8,9]],"date-time":"2017-08-09T12:07:24Z","timestamp":1502280444000},"score":1,"resource":{"primary":{"URL":"http:\/\/www.scielo.br\/scielo.php?script=sci_arttext&pid=S0074-02762017000800561&lng=en&tlng=en"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2017,8]]},"references-count":30,"journal-issue":{"issue":"8","published-print":{"date-parts":[[2017,8]]}},"alternative-id":["S0074-02762017000800561"],"URL":"https:\/\/doi.org\/10.1590\/0074-02760160529","relation":{},"ISSN":["0074-0276"],"issn-type":[{"value":"0074-0276","type":"electronic"}],"subject":[],"published":{"date-parts":[[2017,8]]}}}