{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,29]],"date-time":"2026-09-29T01:36:48Z","timestamp":1790645808126,"version":"4.1.0"},"reference-count":22,"publisher":"FapUNIFESP (SciELO)","issue":"9","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Mem. Inst. Oswaldo Cruz"],"DOI":"10.1590\/0074-02760180200","type":"journal-article","created":{"date-parts":[[2018,6,27]],"date-time":"2018-06-27T19:50:01Z","timestamp":1530129001000},"source":"Crossref","is-referenced-by-count":22,"title":["Meglumine antimoniate intralesional infiltration for localised cutaneous leishmaniasis: a single arm, open label, phase II clinical trial"],"prefix":"10.1590","volume":"113","author":[{"given":"Dario Brock","family":"Ramalho","sequence":"first","affiliation":[{"name":"Funda\u00e7\u00e3o Hospitalar do Estado de Minas Gerais, Brazil"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Rosiana Est\u00e9fane da","family":"Silva","sequence":"additional","affiliation":[{"name":"Funda\u00e7\u00e3o Oswaldo Cruz, Brazil"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Maria Camilo Ribeiro de","family":"Senna","sequence":"additional","affiliation":[{"name":"Funda\u00e7\u00e3o Oswaldo Cruz, Brazil"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hugo Silva Assis","family":"Moreira","sequence":"additional","affiliation":[{"name":"Funda\u00e7\u00e3o Oswaldo Cruz, Brazil"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mariana Junqueira","family":"Pedras","sequence":"additional","affiliation":[{"name":"Funda\u00e7\u00e3o Oswaldo Cruz, Brazil"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Daniel Moreira de","family":"Avelar","sequence":"additional","affiliation":[{"name":"Funda\u00e7\u00e3o Oswaldo Cruz, Brazil"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Lara","family":"Saraiva","sequence":"additional","affiliation":[{"name":"Funda\u00e7\u00e3o Oswaldo Cruz, Brazil"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ana","family":"Rabello","sequence":"additional","affiliation":[{"name":"Funda\u00e7\u00e3o Oswaldo Cruz, Brazil"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Gl\u00e1ucia","family":"Cota","sequence":"additional","affiliation":[{"name":"Funda\u00e7\u00e3o Oswaldo Cruz, Brazil"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"530","published-online":{"date-parts":[[2018,6,21]]},"reference":[{"issue":"2","key":"ref1","article-title":"The cure rate after placebo or no therapy in American cutaneous leishmaniasis a systematic review and meta-analysis","volume":"11","author":"Cota GF","year":"2016","journal-title":"PLoS One"},{"key":"ref2","series-title":"The leishmaniases: old neglected tropical diseases","author":"Bruschi F","year":"2018","edition":"1"},{"issue":"3","key":"ref3","doi-asserted-by":"crossref","first-page":"153","DOI":"10.1016\/j.inhe.2012.06.004","article-title":"Local or systemic treatment for New World cutaneous leishmaniasis Re-evaluating the evidence for the risk of mucosal leishmaniasis","volume":"4","author":"Blum J","year":"2012","journal-title":"Int Health"},{"issue":"9","key":"ref4","doi-asserted-by":"crossref","DOI":"10.1371\/journal.pone.0184777","article-title":"Efficacy of pentavalent antimoniate intralesional infiltration therapy for cutaneous leishmaniasis a systematic review","volume":"12","author":"Brito NC","year":"2017","journal-title":"PLoS One"},{"key":"ref5","series-title":"Report of a meeting of the WHO Expert Committee on the control of leishmaniases","year":"2010"},{"key":"ref6","series-title":"Leishmaniasis en las Am\u00e9ricas: recomendaciones para el tratamiento. Catalogaci\u00f3n en la Fuente. Organizaci\u00f3n Panamericana de la Salud","year":"2013"},{"issue":"3","key":"ref7","doi-asserted-by":"crossref","DOI":"10.1371\/journal.pntd.0002130","article-title":"Methodology of clinical trials aimed at assessing interventions for cutaneous leishmaniasis","volume":"7","author":"Olliaro P","year":"2013","journal-title":"PLoS Negl Trop Dis"},{"issue":"2","key":"ref8","doi-asserted-by":"crossref","first-page":"71","DOI":"10.1590\/0074-027601700125","article-title":"Towards a standard protocol for antimony intralesional infiltration technique for cutaneous leishmaniasis treatment","volume":"113","author":"da Silva RE","year":"2018","journal-title":"Mem Inst Oswaldo Cruz"},{"key":"ref9","series-title":"Division of AIDS (DAIDS) table for grading the severity of adult and pediatric adverse events","year":"2014"},{"key":"ref10","series-title":"WHO Collaborating Centre for international drug monitoring","year":"2018"},{"issue":"8","key":"ref11","doi-asserted-by":"crossref","first-page":"512","DOI":"10.1590\/0074-02760160183","article-title":"Intralesional meglumine antimoniate for the treatment of localised cutaneous leishmaniasis a retrospective review of a Brazilian referral centre","volume":"111","author":"da Silva RE","year":"2016","journal-title":"Mem Inst Oswaldo Cruz"},{"issue":"6","key":"ref12","doi-asserted-by":"crossref","first-page":"463","DOI":"10.1046\/j.1365-4362.1997.00188.x","article-title":"Intralesional therapy of American cutaneous leishmaniasis with pentavalent antimony in Rio de Janeiro, Brazil - an area of Leishmania (V ) braziliensis transmission","volume":"36","author":"Oliveira-Neto MP","year":"1997","journal-title":"Int J Dermatol"},{"issue":"4","key":"ref13","first-page":"201","article-title":"Tratamento da leishmanise tegumentar americana com inje\u00e7\u00f6es intralesionais de n-metil-glucamina","volume":"65","author":"Gadelha AR","year":"1990","journal-title":"An Bras Dermatol"},{"key":"ref14","series-title":"Avalia\u00e7\u00e3o da resposta terap\u00eautica de 272 pacientes com leishmaniose tegumentar americana tratados com baixas doses de antim\u00f4nio pentavalente","year":"2006"},{"issue":"2","key":"ref15","doi-asserted-by":"crossref","first-page":"257","DOI":"10.4269\/ajtmh.2012.11-0612","article-title":"Intralesional meglumine antimoniate for treatment of cutaneous leishmaniasis patients with contraindication to systemic therapy from Rio de Janeiro (2000 to 2006)","volume":"87","author":"Vasconcellos EC","year":"2012","journal-title":"Am J Trop Med Hyg"},{"issue":"9","key":"ref16","doi-asserted-by":"crossref","first-page":"1255","DOI":"10.1093\/cid\/cit049","article-title":"Intralesional antimony for single lesions of bolivian cutaneous leishmaniasis","volume":"56","author":"Soto J","year":"2013","journal-title":"Clin Infect Dis"},{"issue":"4","key":"ref17","doi-asserted-by":"crossref","first-page":"852","DOI":"10.4269\/ajtmh.15-0640","article-title":"Intralesional pentamidine a novel therapy for single lesions of Bolivian cutaneous leishmaniasis","volume":"94","year":"2016","journal-title":"Am J Trop Med Hyg"},{"issue":"2","key":"ref18","doi-asserted-by":"crossref","first-page":"109","DOI":"10.1111\/j.1365-4632.2008.03417.x","article-title":"Treatment of New World cutaneous leishmaniasis - a systematic review with a meta-analysis","volume":"47","author":"Tuon FF","year":"2008","journal-title":"Int J Dermatol"},{"issue":"2","key":"ref19","doi-asserted-by":"crossref","first-page":"210","DOI":"10.4269\/ajtmh.2008.78.210","article-title":"Efficacy of miltefosine for Bolivian cutaneous leishmaniasis","volume":"78","author":"Soto J","year":"2008","journal-title":"Am J Trop Med Hyg"},{"issue":"1","key":"ref20","doi-asserted-by":"crossref","DOI":"10.1371\/journal.pntd.0006141","article-title":"Harmonized clinical trial methodologies for localized cutaneous leishmaniasis and potential for extensive network with capacities for clinical evaluation","volume":"12","author":"Olliaro P","year":"2018","journal-title":"PLoS Negl Trop Dis"},{"key":"ref21","doi-asserted-by":"crossref","first-page":"3126","DOI":"10.1128\/JCM.41.7.3126-3132.2003","article-title":"Genetic polymorphism and molecular epidemiology of Leishmania (Viannia) braziliensis from different hosts and geographic areas in Brazil","volume":"41","author":"Cupolillo E","year":"2003","journal-title":"J Clin Microbiol"},{"key":"ref22","series-title":"An\u00e1lise temporal, espacial e avalia\u00e7\u00e3o dos fatores associados a mortalidade por leishmaniose tegumentar no Brasil","author":"Senra CSA","year":"2018"}],"container-title":["Mem\u00f3rias do Instituto Oswaldo Cruz"],"original-title":[],"link":[{"URL":"http:\/\/www.scielo.br\/pdf\/mioc\/v113n9\/1678-8060-mioc-113-09-e180200.pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2019,10,20]],"date-time":"2019-10-20T02:24:10Z","timestamp":1571538250000},"score":1,"resource":{"primary":{"URL":"http:\/\/www.scielo.br\/scielo.php?script=sci_arttext&pid=S0074-02762018000900300&lng=en&tlng=en"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2018,6,21]]},"references-count":22,"journal-issue":{"issue":"9","published-online":{"date-parts":[[2018]]}},"alternative-id":["S0074-02762018000900300"],"URL":"https:\/\/doi.org\/10.1590\/0074-02760180200","relation":{},"ISSN":["1678-8060","0074-0276"],"issn-type":[{"value":"1678-8060","type":"electronic"},{"value":"0074-0276","type":"print"}],"subject":[],"published":{"date-parts":[[2018,6,21]]}}}