{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,26]],"date-time":"2026-08-26T14:43:30Z","timestamp":1787755410277,"version":"build-2784847793"},"reference-count":31,"publisher":"FapUNIFESP (SciELO)","license":[{"start":{"date-parts":[[2019,1,1]],"date-time":"2019-01-01T00:00:00Z","timestamp":1546300800000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"},{"start":{"date-parts":[[2019,1,1]],"date-time":"2019-01-01T00:00:00Z","timestamp":1546300800000},"content-version":"am","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"},{"start":{"date-parts":[[2019,1,1]],"date-time":"2019-01-01T00:00:00Z","timestamp":1546300800000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Mem. Inst. Oswaldo Cruz"],"DOI":"10.1590\/0074-02760180450","type":"journal-article","created":{"date-parts":[[2018,12,15]],"date-time":"2018-12-15T18:54:19Z","timestamp":1544900059000},"source":"Crossref","is-referenced-by-count":12,"title":["Importance of cerebrospinal fluid investigation during dengue infection in Brazilian Amazonia Region"],"prefix":"10.1590","volume":"114","author":[{"given":"Michele de Souza","family":"Bastos","sequence":"first","affiliation":[{"name":"Funda\u00e7\u00e3o de Medicina Tropical Dr Heitor Vieira Dourado,  Brazil"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Valquiria do Carmo Alves","family":"Martins","sequence":"additional","affiliation":[{"name":"Funda\u00e7\u00e3o Centro de Controle de Oncologia do Estado do Amazonas,  Brasil"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Nat\u00e1lia Lessa da","family":"Silva","sequence":"additional","affiliation":[{"name":"Funda\u00e7\u00e3o de Medicina Tropical Dr Heitor Vieira Dourado,  Brazil"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Samya","family":"Jezine","sequence":"additional","affiliation":[{"name":"Funda\u00e7\u00e3o de Medicina Tropical Dr Heitor Vieira Dourado,  Brazil"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"S\u00e9rgio","family":"Pinto","sequence":"additional","affiliation":[{"name":"Funda\u00e7\u00e3o de Medicina Tropical Dr Heitor Vieira Dourado,  Brazil"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Valderjane","family":"Aprigio","sequence":"additional","affiliation":[{"name":"Funda\u00e7\u00e3o de Medicina Tropical Dr Heitor Vieira Dourado,  Brazil"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Rossicleia Lins","family":"Monte","sequence":"additional","affiliation":[{"name":"Funda\u00e7\u00e3o de Medicina Tropical Dr Heitor Vieira Dourado,  Brazil"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Silvio","family":"Fragoso","sequence":"additional","affiliation":[{"name":"Funda\u00e7\u00e3o de Medicina Tropical Dr Heitor Vieira Dourado,  Brazil"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Marzia","family":"Puccioni-Sohler","sequence":"additional","affiliation":[{"name":"Universidade Federal do Estado do Rio de Janeiro,  Brazil"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"530","published-online":{"date-parts":[[2019]]},"reference":[{"key":"ref1","series-title":"Dengue guidelines for diagnosis, treatment, prevention and control","year":"2009"},{"issue":"2","key":"ref2","first-page":"311","article-title":"The indigenous contribution to the formation of the population of the Brazilian Amazon region","volume":"18","author":"Santos SEB","year":"1995","journal-title":"Rev Bras Gen"},{"issue":"6","key":"ref3","first-page":"476","article-title":"Exanthematous diseases and the first epidemic of dengue to occur in Manaus, Amazonas, state, Brazil, during 1998-1999","volume":"37","author":"Figueiredo RM","year":"2004","journal-title":"Rev Soc Bras Med Trop"},{"issue":"1","key":"ref4","doi-asserted-by":"crossref","first-page":"18","DOI":"10.1590\/S0037-86822009000100005","article-title":"Dengue em crian\u00e7a aspectos cl\u00ednicos e epidemiol\u00f3gicos, Manaus, estado do Amazonas, no per\u00edodo de 2006 e 2007","volume":"42","author":"Rocha LA","year":"2009","journal-title":"Rev Soc Bras Med Trop"},{"issue":"3","key":"ref5","doi-asserted-by":"crossref","first-page":"393","DOI":"10.1590\/S0037-86822012000300022","article-title":"Simultaneous circulation of all four dengue serotypes in Manaus, state of Amazonas, Brazil in 2011","volume":"45","author":"Bastos MS","year":"2012","journal-title":"Rev Soc Bras Med Trop"},{"issue":"2","key":"ref6","doi-asserted-by":"crossref","first-page":"123","DOI":"10.1590\/0004-282x20160189","article-title":"Dengue infection in the nervous system lessons learned for Zika and Chikungunya","volume":"75","author":"Puccioni-Sohler M","year":"2017","journal-title":"Arq Neuropsiquiatr"},{"issue":"6","key":"ref7","doi-asserted-by":"crossref","DOI":"10.1371\/journal.pone.0100535","article-title":"Clinical and virological descriptive study in the 2011 outbreak of dengue in the Amazonas, Brazil","volume":"9","author":"Martins VC","year":"2014","journal-title":"PLoS One"},{"key":"ref8","series-title":"Manual de vigil\u00e2ncia sentinela de doen\u00e7as neuroinvasivas por arbov\u00edrus (Sentinel Surveillance Manual for Neuroinvasive Arboviral Diseases)","year":"2017","edition":"1"},{"key":"ref9","series-title":"Diagn\u00f3stico de neuroinfec\u00e7\u00e3o com abordagem dos exames do l\u00edquido cefalorraquidiano e neuroimagem","first-page":"95","volume-title":"Infec\u00e7\u00f5es virais do sistema nervoso central","author":"Puccioni-Sohler M","year":"2008","edition":"1"},{"issue":"1","key":"ref10","doi-asserted-by":"crossref","first-page":"153","DOI":"10.4269\/ajtmh.1987.36.153","article-title":"Detecting artificial antidengue IgM immune complexes using an enzyme-linked immunosorbent assay","volume":"36","author":"Kuno G","year":"1987","journal-title":"Am J Trop Med Hyg"},{"issue":"3","key":"ref11","doi-asserted-by":"crossref","first-page":"545","DOI":"10.1128\/JCM.30.3.545-551.1992","article-title":"Rapid detection and typing of dengue viruses from clinical samples by using reverse transcriptase-polymerase chain reaction","volume":"30","author":"Lanciotti RS","year":"1992","journal-title":"J Clin Microbiol"},{"key":"ref12","first-page":"95","article-title":"BioEdit a user-friendly biological sequence alignment editor and analysis program for Windows 95\/98\/NT","volume":"41","author":"Hall TA","year":"1999","journal-title":"Nucl Acids Symp Ser"},{"issue":"10","key":"ref13","doi-asserted-by":"crossref","first-page":"2731","DOI":"10.1093\/molbev\/msr121","article-title":"MEGA5 molecular evolutionary genetics analysis using maximum likelihood, evolutionary distance, and maximum parsimony methods","volume":"28","author":"Tamura K","year":"2011","journal-title":"Mol Biol Evol"},{"issue":"12","key":"ref14","doi-asserted-by":"crossref","first-page":"4426","DOI":"10.1128\/JCM.39.12.4426-4432.2001","article-title":"Laboratory diagnosis of common herpesvirus infections of the central nervous system by a multiplex PCR assay","volume":"39","author":"Markoulatos P","year":"2001","journal-title":"J Clin Microbiol"},{"issue":"2","key":"ref15","doi-asserted-by":"crossref","first-page":"696","DOI":"10.1128\/JCM.43.2.696-702.2005","article-title":"Duplex reverse transcription PCR followed by nested PCR assays for detection and identification of Brazilian alphaviruses and flaviviruses","volume":"43","author":"Bronzoni RVM","year":"2005","journal-title":"J Clin Microbiol"},{"issue":"8","key":"ref16","doi-asserted-by":"crossref","first-page":"1232","DOI":"10.3201\/eid1408.080287","article-title":"Genetic and serologic properties of Zika virus associated with an epidemic, Yap state, Micronesia, 2007","volume":"14","author":"Lanciotti RS","year":"2008","journal-title":"Emerg Infect Dis"},{"issue":"1","key":"ref17","doi-asserted-by":"crossref","first-page":"49","DOI":"10.1046\/j.1439-0450.2002.00535.x","article-title":"Specific detection of chikungunya virus using a RT-PCR\/nested PCR combination","volume":"49","author":"Pfeffer M","year":"2002","journal-title":"J Vet Med B Infect Dis Vet Public Health"},{"issue":"1","key":"ref18","doi-asserted-by":"crossref","first-page":"160","DOI":"10.1128\/JCM.30.1.160-165.1992","article-title":"General primer-mediated polymerase chain reaction for detection of enteroviruses application for diagnostic routine and persistent infections","volume":"30","author":"Zoll GJ","year":"1992","journal-title":"J Clin Microbiol"},{"key":"ref19","series-title":"Acute encephalopathy associated with dengue infection","author":"Sanguansermsri T","year":"1976"},{"key":"ref20","doi-asserted-by":"crossref","first-page":"1053","DOI":"10.1016\/S0140-6736(00)02036-5","article-title":"Neurological manifestations of dengue infection","volume":"355","author":"Solomon T","year":"2000","journal-title":"Lancet"},{"key":"ref21","doi-asserted-by":"crossref","first-page":"848","DOI":"10.4269\/ajtmh.2001.65.848","article-title":"Prospective case-control study of encephalopathy in children with dengue hemorrhagic fever","volume":"65","author":"Cam BV","year":"2001","journal-title":"Am J Trop Med Hyg"},{"issue":"1-2","key":"ref22","doi-asserted-by":"crossref","first-page":"36","DOI":"10.1016\/j.jns.2007.09.040","article-title":"Involvement of the central nervous system in patients with dengue virus infection","volume":"267","author":"Domingues RB","year":"2008","journal-title":"J Neurol Sci"},{"issue":"9","key":"ref23","doi-asserted-by":"crossref","first-page":"906","DOI":"10.1016\/S1474-4422(13)70150-9","article-title":"Neurological complications of dengue virus infection","volume":"12","author":"Carod-Artal FJ","year":"2013","journal-title":"Lancet Neurol"},{"key":"ref24","first-page":"677","author":"Ara\u00fajo F","year":"2012"},{"issue":"1","key":"ref25","doi-asserted-by":"crossref","first-page":"115","DOI":"10.3201\/eid2301.160817","article-title":"Meningitis associated with simultaneous infection by multiple dengue virus serotypes in Children, Brazil","volume":"23","author":"Marinho PE","year":"2017","journal-title":"Emerg Infect Dis"},{"issue":"9","key":"ref26","doi-asserted-by":"crossref","first-page":"1522","DOI":"10.1002\/jmv.23953","article-title":"Detection of herpesvirus, enterovirus, and arbovirus infection in patients with suspected central nervous system viral infection in the Western Brazilian Amazon","volume":"86","author":"Bastos MS","year":"2014","journal-title":"J Med Virol"},{"issue":"1","key":"ref27","doi-asserted-by":"crossref","first-page":"19","DOI":"10.1016\/j.jns.2006.05.068","article-title":"Dengue infection neurological manifestations and cerebrospinal fluid (CSF) analysis","volume":"249","author":"Soares CN","year":"2006","journal-title":"J Neurol Sci"},{"issue":"375","key":"ref28","doi-asserted-by":"crossref","first-page":"390","DOI":"10.1016\/j.jns.2017.02.025","article-title":"Etiological agents of viral meningitis in children from a dengue-endemic area, Southeast region of Brazil","volume":"15","author":"de Oliveira DB","year":"2017","journal-title":"J Neurol Sci"},{"issue":"Suppl. 1","key":"ref29","doi-asserted-by":"crossref","first-page":"20","DOI":"10.1590\/0037-8682-0133-2013","article-title":"Arboviral diseases in the Western Brazilian Amazon: a perspective and analysis from a tertiary health & research center in Manaus, state of Amazonas","volume":"48","author":"Mour\u00e3o MP","year":"2015","journal-title":"Rev Soc Bras Med Trop"},{"issue":"2","key":"ref30","doi-asserted-by":"crossref","first-page":"127","DOI":"10.1002\/ajpa.1330580204","article-title":"Blood polymorphisms and racial admixture in two Brazilian populations","volume":"58","author":"Franco MH","year":"1982","journal-title":"Am J Phys Anthrop"},{"issue":"4","key":"ref31","doi-asserted-by":"crossref","first-page":"607","DOI":"10.1353\/hub.2002.0041","article-title":"Ethnic admixture composition of two Western Amazonian Populations","volume":"74","author":"Ferreira RGM","year":"2002","journal-title":"Hum Biol"}],"container-title":["Mem\u00f3rias do Instituto Oswaldo Cruz"],"original-title":[],"link":[{"URL":"http:\/\/www.scielo.br\/pdf\/mioc\/v114\/1678-8060-mioc-114-e180450.pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2020,1,24]],"date-time":"2020-01-24T13:24:27Z","timestamp":1579872267000},"score":1,"resource":{"primary":{"URL":"http:\/\/www.scielo.br\/scielo.php?script=sci_arttext&pid=S0074-02762019000100300&tlng=en"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2019]]},"references-count":31,"alternative-id":["S0074-02762019000100300"],"URL":"https:\/\/doi.org\/10.1590\/0074-02760180450","relation":{},"ISSN":["1678-8060","0074-0276"],"issn-type":[{"value":"1678-8060","type":"electronic"},{"value":"0074-0276","type":"print"}],"subject":[],"published":{"date-parts":[[2019]]},"article-number":"e180450"}}