{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,10,2]],"date-time":"2025-10-02T13:43:49Z","timestamp":1759412629256,"version":"3.41.2"},"reference-count":26,"publisher":"FapUNIFESP (SciELO)","license":[{"start":{"date-parts":[[2019,1,1]],"date-time":"2019-01-01T00:00:00Z","timestamp":1546300800000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"},{"start":{"date-parts":[[2019,1,1]],"date-time":"2019-01-01T00:00:00Z","timestamp":1546300800000},"content-version":"am","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"},{"start":{"date-parts":[[2019,1,1]],"date-time":"2019-01-01T00:00:00Z","timestamp":1546300800000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Mem. Inst. Oswaldo Cruz"],"DOI":"10.1590\/0074-02760180517","type":"journal-article","created":{"date-parts":[[2019,2,28]],"date-time":"2019-02-28T03:03:44Z","timestamp":1551323024000},"source":"Crossref","is-referenced-by-count":4,"title":["Immunogenicity and safety of the combined vaccine for measles, mumps, and rubella isolated or combined with the varicella component administered at 3-month intervals: randomised study"],"prefix":"10.1590","volume":"114","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-9484-9926","authenticated-orcid":false,"given":"Eliane Matos dos","family":"Santos","sequence":"first","affiliation":[{"name":"Funda\u00e7\u00e3o Oswaldo Cruz-Fiocruz,  Brazil"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Tatiana Guimar\u00e3es","family":"Noronha","sequence":"additional","affiliation":[{"name":"Funda\u00e7\u00e3o Oswaldo Cruz-Fiocruz,  Brazil"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Isabelle Soares","family":"Alves","sequence":"additional","affiliation":[{"name":"Funda\u00e7\u00e3o Oswaldo Cruz-Fiocruz,  Brazil"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Robson Leite de Souza","family":"Cruz","sequence":"additional","affiliation":[{"name":"Funda\u00e7\u00e3o Oswaldo Cruz-Fiocruz,  Brazil"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Clara Lucy de Vasconcellos","family":"Ferroco","sequence":"additional","affiliation":[{"name":"Funda\u00e7\u00e3o Oswaldo Cruz-Fiocruz,  Brazil"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ricardo Cristiano","family":"Brum","sequence":"additional","affiliation":[{"name":"Funda\u00e7\u00e3o Oswaldo Cruz-Fiocruz,  Brazil"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Patricia Mouta Nunes de","family":"Oliveira","sequence":"additional","affiliation":[{"name":"Funda\u00e7\u00e3o Oswaldo Cruz-Fiocruz,  Brazil"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Marilda Mendon\u00e7a","family":"Siqueira","sequence":"additional","affiliation":[{"name":"Funda\u00e7\u00e3o Oswaldo Cruz-Fiocruz,  Brazil"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Mariza Cristina","family":"Lima","sequence":"additional","affiliation":[{"name":"Funda\u00e7\u00e3o Oswaldo Cruz-Fiocruz,  Brazil"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Francisco Luzio de Paula","family":"Ramos","sequence":"additional","affiliation":[{"name":"Instituto Evandro Chagas,  Brasil"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Camila de Marco","family":"Bragagnolo","sequence":"additional","affiliation":[{"name":"Instituto Evandro Chagas,  Brasil"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Luiz Antonio Bastos","family":"Camacho","sequence":"additional","affiliation":[{"name":"Funda\u00e7\u00e3o Oswaldo Cruz-Fiocruz,  Brazil"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Maria de Lourdes de Sousa","family":"Maia","sequence":"additional","affiliation":[{"name":"Funda\u00e7\u00e3o Oswaldo Cruz-Fiocruz,  Brazil"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"530","published-online":{"date-parts":[[2019]]},"reference":[{"year":"2013","author":"Imuniza\u00e7\u00f5es Minist\u00e9rio da Sa\u00fade\/Secretaria de Vigil\u00e2ncia em Sa\u00fade\/Departamento de Vigil\u00e2ncia Epidemiol\u00f3gica\/Coordena\u00e7\u00e3o-Geral do Programa Nacional de","key":"ref1"},{"issue":"3","key":"ref2","doi-asserted-by":"crossref","first-page":"335","DOI":"10.1590\/0074-0276130351","article-title":"Immune response to the mumps component of the MMR vaccine in the routine of immunisation services in the Brazilian National Immunisation Program","volume":"109","author":"dos Santos EM","year":"2014","journal-title":"Mem Inst Oswaldo Cruz"},{"key":"ref3","article-title":"Mumps vaccine. In SA Plotkin, WA Orestein, PA Offit, editors.","author":"Rubin SA","year":"2013","journal-title":"Vaccines"},{"key":"ref4","doi-asserted-by":"crossref","first-page":"6327","DOI":"10.1016\/j.vaccine.2011.05.019","article-title":"Mutual interference on the immune response to yellow fever vaccine and a combined vaccine against measles, mumps and rubella","volume":"29","author":"Silva JRN","year":"2011","journal-title":"Vaccine"},{"issue":"1","key":"ref5","doi-asserted-by":"crossref","first-page":"52","DOI":"10.1016\/S0197-2456(01)00202-1","article-title":"Showing a treatment is good because it is not bad when does \"noninferiority\" imply effectiveness","volume":"23","author":"Blackwelder WC","year":"2002","journal-title":"Control Clin Trials"},{"key":"ref6","doi-asserted-by":"crossref","first-page":"429","DOI":"10.1080\/10543400600719251","article-title":"Statistical considerations for noninferiority\/equivalence trials in vaccine development","volume":"16","author":"Wang WWB","year":"2006","journal-title":"J Biopharm Stat"},{"key":"ref7","article-title":"Measles vaccine. In SA Plotkin, WA Orestein, PA Offit, editors.","author":"Rubin SA","year":"2013","journal-title":"Vaccines"},{"key":"ref8","first-page":"113","article-title":"Concomitant administration of varicella vaccine with combined measles, mumps, and rubella vaccine in healthy children aged 12 to 24 months of age","volume":"20","author":"Stuck B","year":"2002","journal-title":"Asian Pac J Allergy Immunol"},{"issue":"1","key":"ref9","doi-asserted-by":"crossref","first-page":"91","DOI":"10.7774\/cevr.2014.3.1.91","article-title":"Immunogenicity and safety of a tetravalent measles-mumps-rubella-varicella vaccine an open-labeled, randomized trial in healthy Korean children","volume":"3","author":"Cha SH","year":"2014","journal-title":"Clin Exp Vaccine Res"},{"issue":"3-4","key":"ref10","doi-asserted-by":"crossref","first-page":"281","DOI":"10.1016\/S0264-410X(02)00459-0","article-title":"Reactogenicity and immunogenicity of a live attenuated tetravalent measles-mumps-rubella-varicella (MMRV) vaccine","volume":"21","author":"Nolan T","year":"2002","journal-title":"Vaccine"},{"issue":"25","key":"ref11","doi-asserted-by":"crossref","first-page":"2796","DOI":"10.1016\/S0264-410X(00)00081-5","article-title":"Reactogenicity and immunogenicity of a new combined measles-mumps-rubella vaccine results of a multicentre trial","volume":"18","author":"Crovari P","year":"2000","journal-title":"Vaccine"},{"issue":"44","key":"ref12","article-title":"Combination measles-mumps-rubella-varicella vaccine in healthy children","volume":"94","author":"Ma S-J","year":"2015","journal-title":"Medicine (Baltimore)"},{"key":"ref13","doi-asserted-by":"crossref","first-page":"222","DOI":"10.1007\/BF02962367","article-title":"Comparative study of reactogenicity and immunogenicity of new and established measles, mumps and rubella vaccines in healthy children","volume":"26","author":"Usonis V","year":"1998","journal-title":"Infection"},{"key":"ref14","doi-asserted-by":"crossref","first-page":"326","DOI":"10.1007\/s15010-007-6337-z","article-title":"Safety and immunogenicity of early vaccination with two doses of tetravalent measles-mumps-rubella-varicella (MMRV) vaccine in healthy children from 9 months of age","volume":"35","author":"Goh P","year":"2007","journal-title":"Infection"},{"key":"ref15","first-page":"1","article-title":"Comtemp","volume":"41","author":"Martins RM","year":"2015","journal-title":"ClinTrials"},{"issue":"8","key":"ref16","doi-asserted-by":"crossref","first-page":"724","DOI":"10.1097\/INF.0b013e318170bb22","article-title":"Immunogenicity and safety assessments after one and two doses of a refrigerator-stable tetravalent measles-mumps-rubella-varicella vaccine in healthy children during the second year of life","volume":"27","author":"Schuster V","year":"2008","journal-title":"Pediatric Infect Dis J"},{"issue":"47","key":"ref17","doi-asserted-by":"crossref","first-page":"6504","DOI":"10.1016\/j.vaccine.2009.07.076","article-title":"A combined measles, mumps, rubella and varicella vaccine (Priorix-Tetra) immunogenicity and safety profile","volume":"27","author":"Czajka H","year":"2009","journal-title":"Vaccine"},{"issue":"6","key":"ref18","doi-asserted-by":"crossref","first-page":"1308","DOI":"10.4161\/hv.24035","article-title":"Immunogenicity and safety of combined measles-mumps-rubella-varicella vaccine using new measles and rubella working seeds in healthy children in Taiwan and Singapore a phase II, randomized, double-blind trial","volume":"9","author":"Huang LM","year":"2013","journal-title":"Hum Vaccin Immunother"},{"key":"ref19","doi-asserted-by":"crossref","DOI":"10.1136\/bmjopen-2014-007202","article-title":"Immunogenicity and safety of early vaccination with two doses of a combined measles-mumps-rubella-varicella vaccine in healthy Indian children from 9 months of age a phase III, randomised, non-inferiority trial","volume":"5","author":"Lalwani S","year":"2015","journal-title":"BMJ Open"},{"issue":"3","key":"ref20","doi-asserted-by":"crossref","first-page":"446","DOI":"10.1016\/j.vaccine.2008.10.064","article-title":"Immunogenicity and safety of measles-mumps-rubella-varicella (MMRV) vaccine followed by one dose of varicella vaccine in children aged 15 months-2years or 2-6 years primed with measles-mumps-rubella (MMR) vaccine","volume":"27","author":"Gillet Y","year":"2009","journal-title":"Vaccine"},{"key":"ref21","article-title":"Current mumps vaccination recommendations and epidemiology in the United States.","author":"Marin M","year":"2017","journal-title":"In Advisory Committee on Immunization Practices (ACIP) Meeting"},{"author":"Information. Varilrix(r) Product","key":"ref22"},{"issue":"36","key":"ref23","doi-asserted-by":"crossref","first-page":"4278","DOI":"10.1016\/j.vaccine.2016.07.009","article-title":"The immunogenicity and safety of a tetravalent measles-mumps-rubella-varicella vaccine when co-administered with conjugated meningococcal C vaccine to healthy children A phase IIIb, randomized, multi-center study in Italy","volume":"34","author":"Durando P","year":"2016","journal-title":"Vaccine"},{"journal-title":"Interpreting laboratory tests","article-title":"Chickenpox (Varicella)","author":"Prevention Centers for Disease Control and","key":"ref24"},{"edition":"2","year":"2008","series-title":"Manual de vigil\u00e2ncia epidemiol\u00f3gica de eventos adversos p\u00f3s-vacina\u00e7\u00e3o","key":"ref25"},{"year":"2017","series-title":"Nota Informativa N\u00ba 135 - SEI\/2017-CGPNI\/DEVIT\/SVS\/MS","author":"Sa\u00fade Minist\u00e9rio da","key":"ref26"}],"container-title":["Mem\u00f3rias do Instituto Oswaldo Cruz"],"original-title":[],"link":[{"URL":"http:\/\/www.scielo.br\/pdf\/mioc\/v114\/1678-8060-mioc-114-e180517.pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2020,1,24]],"date-time":"2020-01-24T19:34:45Z","timestamp":1579894485000},"score":1,"resource":{"primary":{"URL":"http:\/\/www.scielo.br\/scielo.php?script=sci_arttext&pid=S0074-02762019000100314&tlng=en"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2019]]},"references-count":26,"alternative-id":["S0074-02762019000100314"],"URL":"https:\/\/doi.org\/10.1590\/0074-02760180517","relation":{},"ISSN":["1678-8060","0074-0276"],"issn-type":[{"type":"electronic","value":"1678-8060"},{"type":"print","value":"0074-0276"}],"subject":[],"published":{"date-parts":[[2019]]},"article-number":"e180517"}}